FR15C0028I1 - - Google Patents

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Publication number
FR15C0028I1
FR15C0028I1 FR15C0028C FR15C0028I1 FR 15C0028 I1 FR15C0028 I1 FR 15C0028I1 FR 15C0028 C FR15C0028 C FR 15C0028C FR 15C0028 I1 FR15C0028 I1 FR 15C0028I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of FR15C0028I1 publication Critical patent/FR15C0028I1/fr
Application granted granted Critical
Publication of FR15C0028I2 publication Critical patent/FR15C0028I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
FR15C0028C 2002-07-29 2015-03-27 Fabrication de tiacumicine Active FR15C0028I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39995602P 2002-07-29 2002-07-29
PCT/US2003/021977 WO2004014295A2 (en) 2002-07-29 2003-07-15 Tiacumicin production

Publications (2)

Publication Number Publication Date
FR15C0028I1 true FR15C0028I1 (bs) 2015-05-15
FR15C0028I2 FR15C0028I2 (fr) 2015-11-13

Family

ID=31715689

Family Applications (1)

Application Number Title Priority Date Filing Date
FR15C0028C Active FR15C0028I2 (fr) 2002-07-29 2015-03-27 Fabrication de tiacumicine

Country Status (18)

Country Link
US (4) US7507564B2 (bs)
EP (2) EP1539977B1 (bs)
JP (3) JP2005534332A (bs)
KR (1) KR100972542B1 (bs)
CN (1) CN100519757C (bs)
AU (1) AU2003251902B2 (bs)
BE (1) BE2015C017I2 (bs)
CA (1) CA2494742C (bs)
CY (1) CY2015015I1 (bs)
DK (1) DK1539977T3 (bs)
ES (1) ES2527052T3 (bs)
FR (1) FR15C0028I2 (bs)
HU (1) HUS1500016I1 (bs)
LU (1) LU92684I2 (bs)
NL (1) NL300727I2 (bs)
PT (1) PT1539977E (bs)
SI (1) SI1539977T1 (bs)
WO (1) WO2004014295A2 (bs)

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US20070105791A1 (en) * 2002-07-29 2007-05-10 Optimer Pharmaceuticals, Inc. Method of treating clostridium difficile-associated diarrhea
JP2005534332A (ja) * 2002-07-29 2005-11-17 オプティマー ファーマシューティカルズ、インコーポレイテッド チアクマイシン生産
US7906489B2 (en) * 2004-05-14 2011-03-15 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof
PL2070530T3 (pl) * 2004-05-14 2016-06-30 Merck Sharp & Dohme Leczenie chorób związanych ze stosowaniem antybiotyków
JP5166040B2 (ja) * 2005-01-31 2013-03-21 オプティマー ファーマシューティカルズ、インコーポレイテッド １８員大環状化合物及びその類似化合物
US7378508B2 (en) * 2007-01-22 2008-05-27 Optimer Pharmaceuticals, Inc. Polymorphic crystalline forms of tiacumicin B
AU2012200784B2 (en) * 2005-01-31 2013-07-11 Merck Sharp & Dohme Llc 18-membered macrocycles and analogs thereof
AU2006304868B2 (en) * 2005-10-21 2013-02-21 Merck Sharp & Dohme Corp. Method of treating clostridium difficile-associated diarrhea
US20080176927A1 (en) * 2007-01-19 2008-07-24 Optimer Pharmaceuticals, Inc. Compositions of stable tiacumicins
KR100891313B1 (ko) * 2007-08-17 2009-03-31 (주) 제노텍 담체로 작용하는 흡착성 수지의 제공에 의한 트리사이클로화합물의 생산 및 추출 방법
TWI326284B (en) * 2007-10-26 2010-06-21 Echem Hightech Co Ltd Derivatives of tiacumicin b as anti-cancer agents
TWI523654B (zh) 2007-11-27 2016-03-01 默沙東藥廠 抗生素巨環化合物以及其製造及使用之方法
EP2545023A4 (en) * 2010-02-15 2017-04-12 Abbvie Inc. Process for the preparation of scyllo-inositol
CN103402954A (zh) 2010-10-13 2013-11-20 依兰制药公司 鲨肌醇和相关化合物的合成方法
CN102115757B (zh) * 2010-12-14 2015-10-28 中国科学院南海海洋研究所 台勾霉素的生物合成基因簇及其应用
ITMI20120560A1 (it) 2012-04-05 2013-10-06 Olon Spa Procedimento per la purificazione della tiacumicina b
ITMI20120559A1 (it) * 2012-04-05 2013-10-06 Olon Spa Procedimento migliorato per la produzione di tiacumicina b
EP2855499A1 (en) * 2012-05-10 2015-04-08 Teva Pharmaceutical Works Ltd. Solid state forms of fidaxomycin and processes for preparation thereof
WO2014023616A1 (en) 2012-08-07 2014-02-13 Olon Spa Procedure for the production of tiacumicin b
ITMI20121406A1 (it) * 2012-08-07 2014-02-08 Olon Spa Procedimento per la produzione di tiacumicina b
ITMI20130856A1 (it) * 2013-05-27 2014-11-28 Olon Spa Procedimento per la produzione di tiacumicina b
CN102993251B (zh) * 2012-12-17 2016-03-16 苏州纳微科技有限公司 一种用高效液相色谱纯化台勾霉素b的方法
JO3464B1 (ar) 2013-01-15 2020-07-05 Astellas Pharma Europe Ltd التركيبات الخاصة بمركبات التياكوميسين
US10119158B2 (en) * 2013-04-23 2018-11-06 Concord Biotech Limited Process for the preparation of fidaxomicin
CN103275152B (zh) * 2013-05-29 2015-11-18 华北制药集团新药研究开发有限责任公司 一种高纯度非达霉素的制备方法
CN103275153B (zh) * 2013-06-27 2016-03-23 华北制药集团新药研究开发有限责任公司 一种非达霉素晶体的制备方法
CN104418925B (zh) * 2013-09-05 2018-09-28 重庆乾泰生物医药有限公司 一种制备高纯度非达霉素的方法
CN104513286B (zh) * 2013-09-27 2018-08-17 博瑞生物医药（苏州）股份有限公司 一种分离纯化非达米星的方法
CN104560766B (zh) 2013-10-16 2017-07-28 浙江海正药业股份有限公司 一种游动放线菌菌株及其应用
CN104561198B (zh) * 2013-10-18 2019-04-12 重庆乾泰生物医药有限公司 一种发酵生产非达霉素的方法
KR102355450B1 (ko) 2013-12-20 2022-01-24 셀리아 파마슈티칼즈 에이피에스 티아쿠미신의 제조를 위한 방법
CN104846044B (zh) * 2014-02-17 2019-02-01 上海医药工业研究院 一种提高非达霉素产量的发酵培养基
WO2015127955A1 (en) 2014-02-25 2015-09-03 Olon S.P.A. A new polymorph of tiacumicin b and process for preparation thereof
KR20160134719A (ko) 2014-03-18 2016-11-23 셀리아 파마슈티칼즈 에이피에스 신규한 다형체 및 신규한 고체 상태의 티아쿠미신 ｂ
CN104946708B (zh) * 2014-03-28 2018-06-12 上海医药工业研究院 一种生产非达霉素的发酵培养基以及发酵方法
CN103880904B (zh) * 2014-03-28 2016-08-24 华北制药集团新药研究开发有限责任公司 非达霉素晶型i及其制备方法
US10137141B2 (en) 2014-05-09 2018-11-27 Astellas Pharma Europe Ltd. Treatment regimen tiacumicin compound
CN104098637B (zh) * 2014-07-09 2017-01-04 浙江海正药业股份有限公司 一种纯化非达霉素的方法
US10548912B2 (en) 2015-07-03 2020-02-04 Astellas Pharma Europe Ltd. Dosage regimen for a tiacumicin compound
IL251499B (en) * 2017-04-02 2019-02-28 Efraty Avi Reverse osmosis installation in a closed circuit with a hydraulic arm for desalination with low energy consumption and a high recovery ratio
CN107236686B (zh) * 2017-06-21 2019-10-15 杭州华东医药集团新药研究院有限公司 一种桔橙指孢囊菌及其在调控微生物代谢物非达霉素中的应用
CN114084964B (zh) * 2020-08-24 2023-02-24 中国石油化工股份有限公司 一种芳香有机化合物废水生物处理促进剂及制备方法和应用

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JP2005534332A (ja) * 2002-07-29 2005-11-17 オプティマー ファーマシューティカルズ、インコーポレイテッド チアクマイシン生産

Also Published As

Publication number Publication date
NL300727I2 (bs) 2016-05-17
AU2003251902A1 (en) 2004-02-25
SI1539977T1 (sl) 2015-01-30
CN100519757C (zh) 2009-07-29
CY2015015I1 (el) 2020-05-29
KR100972542B1 (ko) 2010-07-28
ES2527052T3 (es) 2015-01-20
CA2494742C (en) 2015-05-12
JP2013208131A (ja) 2013-10-10
US20060257981A1 (en) 2006-11-16
WO2004014295A3 (en) 2005-04-14
BE2015C017I2 (bs) 2022-09-22
US20100028970A1 (en) 2010-02-04
DK1539977T3 (en) 2014-11-17
EP1539977B1 (en) 2014-10-08
KR20050053598A (ko) 2005-06-08
US7507564B2 (en) 2009-03-24
JP5729919B2 (ja) 2015-06-03
LU92684I2 (fr) 2015-11-02
CA2494742A1 (en) 2004-02-19
AU2003251902B2 (en) 2008-03-06
CN1688707A (zh) 2005-10-26
HUS1500016I1 (hu) 2017-10-30
FR15C0028I2 (fr) 2015-11-13
JP2010178760A (ja) 2010-08-19
EP1539977A4 (en) 2006-10-11
US8728796B2 (en) 2014-05-20
WO2004014295A2 (en) 2004-02-19
US20130123477A1 (en) 2013-05-16
JP2005534332A (ja) 2005-11-17
JP5907931B2 (ja) 2016-04-26
EP2860241A1 (en) 2015-04-15
US20140296498A1 (en) 2014-10-02
EP1539977A2 (en) 2005-06-15
PT1539977E (pt) 2015-01-14

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