JO3464B1 - التركيبات الخاصة بمركبات التياكوميسين - Google Patents
التركيبات الخاصة بمركبات التياكوميسينInfo
- Publication number
- JO3464B1 JO3464B1 JOP/2014/0006A JOP20140006A JO3464B1 JO 3464 B1 JO3464 B1 JO 3464B1 JO P20140006 A JOP20140006 A JO P20140006A JO 3464 B1 JO3464 B1 JO 3464B1
- Authority
- JO
- Jordan
- Prior art keywords
- compositions
- polymorph
- carrageenan
- solvate
- isomer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
<span dir="RTL">يوفر الاختراع الحالي تركيبة تشتمل على مركب تباكوميسين واحد أو أكثر كمكون فعال، و متجاسم منه، أو صورة متبلرة منه أو ذوابة منه، في توليفة مع سواغ، مختار من المجموعة التي تتكون من صمغ زانتان، كاراجينان، ألجينات صوديوم، صمغ الجوار، سليلوز قابل للتشتيت في الماء (سيليلوز دقيق التبلر و صوديوم كربوكسي ميثيل سليلوز) و خلائط من ذلك. و أيضا، يوفر الاختراع استخدام سواغ، مختار من المجموعة التي تتكون من صمغ زانتان، كاراجينان، ألجينات صوديوم، صمغ الجوار، سيليلوز قابل للتشتيت في الماء (سيليلوز دقيق التبلر و صوديوم كربوكسي ميثيل سليلوز) و خلائط من ذلك كعامل مضاد للرغوة في تركيبة تشتمل كمكون فعال على مركب تياكوميسين، متجاسم منه، صورة متبلرة منه أو ذوابة منه.</span>
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13075002 | 2013-01-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
JO3464B1 true JO3464B1 (ar) | 2020-07-05 |
Family
ID=47563169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2014/0006A JO3464B1 (ar) | 2013-01-15 | 2014-01-13 | التركيبات الخاصة بمركبات التياكوميسين |
Country Status (28)
Country | Link |
---|---|
US (1) | US9808530B2 (ar) |
EP (1) | EP2945613B1 (ar) |
JP (1) | JP6338598B2 (ar) |
KR (1) | KR102181474B1 (ar) |
CN (1) | CN105120840B (ar) |
AR (1) | AR094495A1 (ar) |
AU (1) | AU2014207083B2 (ar) |
CA (1) | CA2904808A1 (ar) |
CY (1) | CY1121459T1 (ar) |
DK (1) | DK2945613T3 (ar) |
EA (1) | EA030049B1 (ar) |
ES (1) | ES2705238T3 (ar) |
GE (1) | GEP201706769B (ar) |
HR (1) | HRP20182110T1 (ar) |
HU (1) | HUE041421T2 (ar) |
IL (1) | IL239899A0 (ar) |
JO (1) | JO3464B1 (ar) |
LT (1) | LT2945613T (ar) |
MD (1) | MD4588C1 (ar) |
NZ (1) | NZ710875A (ar) |
PL (1) | PL2945613T3 (ar) |
PT (1) | PT2945613T (ar) |
RS (1) | RS58119B1 (ar) |
SI (1) | SI2945613T1 (ar) |
TW (1) | TWI646962B (ar) |
UA (1) | UA117004C2 (ar) |
WO (1) | WO2014111254A1 (ar) |
ZA (1) | ZA201505048B (ar) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10137141B2 (en) * | 2014-05-09 | 2018-11-27 | Astellas Pharma Europe Ltd. | Treatment regimen tiacumicin compound |
CN110037992B (zh) * | 2019-05-28 | 2021-05-28 | 杭州华东医药集团新药研究院有限公司 | 一种稳定的非达霉素组合物 |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3000792A (en) | 1957-05-21 | 1961-09-19 | Merck & Co Inc | Antibiotic adsorption process |
GB1458512A (en) | 1973-11-22 | 1976-12-15 | Lepetit Spa | Antibiotic substance |
US4632902A (en) | 1981-08-20 | 1986-12-30 | Becton, Dickinson And Company | Method for detecting biological activity in a body fluid |
US4918174A (en) | 1986-09-26 | 1990-04-17 | Abbott Laboratories | Tiacumicin compounds |
CA2384519C (en) | 1991-03-04 | 2006-08-15 | Bayer Corporation | Automated analyzer |
US5583115A (en) | 1995-05-09 | 1996-12-10 | Abbott Laboratories | Dialkyltiacumicin compounds |
US5767096A (en) | 1996-07-12 | 1998-06-16 | Abbott Laboratories | Bromotiacumicin compounds |
NZ335383A (en) | 1996-11-18 | 2000-10-27 | Biotechnolog Forschung Gmbh | Epothilone C,D,E and F for plant protection and cytostatic effects shown in kidney cells |
JP2000072760A (ja) | 1998-06-19 | 2000-03-07 | Ajinomoto Co Inc | 新規シストチアゾール類縁体 |
JP2000053514A (ja) | 1998-08-06 | 2000-02-22 | Aquas Corp | レジオネラ属細菌が生産する殺菌性物質、これを用いた殺菌剤、水処理剤、スライム抑制剤、及びこれらの製造方法 |
JP2000239266A (ja) | 1999-02-17 | 2000-09-05 | Ajinomoto Co Inc | 新規ポリエン系抗生物質 |
ATE309369T1 (de) | 2000-04-28 | 2005-11-15 | Kosan Biosciences Inc | Heterologe herstellung von polyketiden |
AU2001211213A1 (en) | 2000-10-20 | 2002-04-29 | Galephar M/F | Stable oral formulation containing benzimidazole derivative |
US20030099699A1 (en) | 2001-11-13 | 2003-05-29 | Hanshew Dwight D. | Storage stable thyroxine active drug formulations and methods for their production |
US20070105791A1 (en) | 2002-07-29 | 2007-05-10 | Optimer Pharmaceuticals, Inc. | Method of treating clostridium difficile-associated diarrhea |
US7507564B2 (en) | 2002-07-29 | 2009-03-24 | Optimer Pharmaceuticals, Inc. | Tiacumicin production |
US20080206161A1 (en) * | 2002-10-25 | 2008-08-28 | Dov Tamarkin | Quiescent foamable compositions, steroids, kits and uses thereof |
US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
CA2510465A1 (en) | 2002-12-18 | 2004-07-08 | Pain Therapeutics | Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats |
JP4640821B2 (ja) | 2003-07-24 | 2011-03-02 | 塩野義製薬株式会社 | 難水溶性薬物を含むドライシロップ剤 |
JP3881640B2 (ja) | 2003-08-08 | 2007-02-14 | 塩野義製薬株式会社 | ロラタジンを含むドライシロップ剤 |
LT2305245T (lt) | 2004-05-14 | 2019-03-12 | Merck Sharp & Dohme Corp. | Su antibiotikų vartojimu susijusių ligų gydymas |
US7906489B2 (en) | 2004-05-14 | 2011-03-15 | Optimer Pharmaceuticals, Inc. | 18-membered macrocycles and analogs thereof |
US7378508B2 (en) | 2007-01-22 | 2008-05-27 | Optimer Pharmaceuticals, Inc. | Polymorphic crystalline forms of tiacumicin B |
MX340742B (es) | 2005-01-31 | 2016-07-21 | Merck Sharp & Dohme | Compuestos macrociclicos de 18 miembros y analogos de los mismos. |
US20110104267A1 (en) * | 2005-04-25 | 2011-05-05 | Aurobindo Pharma Limited | Pharmaceutical compositions of antiretrovirals |
CN102503994A (zh) | 2005-10-21 | 2012-06-20 | 奥普蒂姆药物公司 | 治疗艰难梭菌相关的腹泻的方法 |
US20080176927A1 (en) * | 2007-01-19 | 2008-07-24 | Optimer Pharmaceuticals, Inc. | Compositions of stable tiacumicins |
ZA200905337B (en) | 2007-01-22 | 2010-10-27 | Optimer Pharmaceuticals Inc | Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof |
US8999395B2 (en) * | 2007-02-09 | 2015-04-07 | Ceva Sante Animale | Pharmaceutical compositions for oral administration in the form of stabilised aqueous suspensions |
TWI523654B (zh) | 2007-11-27 | 2016-03-01 | 默沙東藥廠 | 抗生素巨環化合物以及其製造及使用之方法 |
JP5608880B2 (ja) * | 2010-02-09 | 2014-10-22 | 林兼産業株式会社 | 嚥下困難者用高栄養ゼリー食品 |
CN102030791B (zh) | 2010-10-28 | 2013-01-23 | 中国科学院南海海洋研究所 | 四种台勾霉素类化合物及其制备方法和在制备抗菌药物中的应用 |
CN102115757B (zh) | 2010-12-14 | 2015-10-28 | 中国科学院南海海洋研究所 | 台勾霉素的生物合成基因簇及其应用 |
-
2014
- 2014-01-13 JO JOP/2014/0006A patent/JO3464B1/ar active
- 2014-01-14 KR KR1020157021986A patent/KR102181474B1/ko active IP Right Grant
- 2014-01-14 JP JP2015553034A patent/JP6338598B2/ja active Active
- 2014-01-14 LT LTEP14701907.9T patent/LT2945613T/lt unknown
- 2014-01-14 ES ES14701907T patent/ES2705238T3/es active Active
- 2014-01-14 CA CA2904808A patent/CA2904808A1/en not_active Abandoned
- 2014-01-14 NZ NZ71087514A patent/NZ710875A/en not_active IP Right Cessation
- 2014-01-14 PT PT14701907T patent/PT2945613T/pt unknown
- 2014-01-14 EP EP14701907.9A patent/EP2945613B1/en active Active
- 2014-01-14 WO PCT/EP2014/000091 patent/WO2014111254A1/en active Application Filing
- 2014-01-14 PL PL14701907T patent/PL2945613T3/pl unknown
- 2014-01-14 MD MDA20150070A patent/MD4588C1/ro active IP Right Grant
- 2014-01-14 EA EA201591226A patent/EA030049B1/ru unknown
- 2014-01-14 UA UAA201506802A patent/UA117004C2/uk unknown
- 2014-01-14 AU AU2014207083A patent/AU2014207083B2/en not_active Ceased
- 2014-01-14 US US14/766,904 patent/US9808530B2/en active Active
- 2014-01-14 RS RS20181542A patent/RS58119B1/sr unknown
- 2014-01-14 GE GEAP201413898A patent/GEP201706769B/en unknown
- 2014-01-14 HU HUE14701907A patent/HUE041421T2/hu unknown
- 2014-01-14 SI SI201430997T patent/SI2945613T1/sl unknown
- 2014-01-14 CN CN201480015374.9A patent/CN105120840B/zh not_active Expired - Fee Related
- 2014-01-14 DK DK14701907.9T patent/DK2945613T3/en active
- 2014-01-15 AR ARP140100152A patent/AR094495A1/es unknown
- 2014-01-15 TW TW103101528A patent/TWI646962B/zh not_active IP Right Cessation
-
2015
- 2015-07-12 IL IL239899A patent/IL239899A0/en active IP Right Grant
- 2015-07-14 ZA ZA2015/05048A patent/ZA201505048B/en unknown
-
2018
- 2018-12-13 HR HRP20182110TT patent/HRP20182110T1/hr unknown
- 2018-12-28 CY CY20181101410T patent/CY1121459T1/el unknown
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