FR10C0056I2 - - Google Patents

Info

Publication number
FR10C0056I2
FR10C0056I2 FR10C0056C FR10C0056C FR10C0056I2 FR 10C0056 I2 FR10C0056 I2 FR 10C0056I2 FR 10C0056 C FR10C0056 C FR 10C0056C FR 10C0056 C FR10C0056 C FR 10C0056C FR 10C0056 I2 FR10C0056 I2 FR 10C0056I2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR10C0056C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8216678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR10C0056(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organon NV filed Critical Organon NV
Publication of FR10C0056I1 publication Critical patent/FR10C0056I1/fr
Application granted granted Critical
Publication of FR10C0056I2 publication Critical patent/FR10C0056I2/fr
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR10C0056C 1994-03-02 2010-12-23 Active FR10C0056I2 (enExample)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94200521 1994-03-02
EP95912188A EP0746317B1 (en) 1994-03-02 1995-03-01 Sublingual or buccal pharmaceutical composition
PCT/EP1995/000765 WO1995023600A1 (en) 1994-03-02 1995-03-01 Sublingual or buccal pharmaceutical composition

Publications (2)

Publication Number Publication Date
FR10C0056I1 FR10C0056I1 (enExample) 2011-01-28
FR10C0056I2 true FR10C0056I2 (enExample) 2011-11-25

Family

ID=8216678

Family Applications (1)

Application Number Title Priority Date Filing Date
FR10C0056C Active FR10C0056I2 (enExample) 1994-03-02 2010-12-23

Country Status (23)

Country Link
US (1) US5763476A (enExample)
EP (1) EP0746317B1 (enExample)
JP (2) JP4099224B2 (enExample)
KR (1) KR100330942B1 (enExample)
CN (1) CN1079670C (enExample)
AT (1) ATE167057T1 (enExample)
AU (1) AU692530B2 (enExample)
BR (2) BR9506924A (enExample)
CA (1) CA2182981C (enExample)
CZ (1) CZ284633B6 (enExample)
DE (2) DE122010000050I2 (enExample)
DK (1) DK0746317T3 (enExample)
ES (1) ES2118584T3 (enExample)
FI (1) FI117923B (enExample)
FR (1) FR10C0056I2 (enExample)
HK (1) HK1008417A1 (enExample)
HU (1) HU225051B1 (enExample)
LU (1) LU91751I2 (enExample)
NO (2) NO308772B1 (enExample)
NZ (1) NZ282394A (enExample)
PL (1) PL180465B1 (enExample)
RU (1) RU2139051C1 (enExample)
WO (1) WO1995023600A1 (enExample)

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AU2418499A (en) * 1997-12-19 1999-07-12 Akzo Nobel N.V. Org-5222 in the treatment of depression
AU2003211051A1 (en) * 2002-02-13 2003-09-04 Michael K. Weibel Drug dose-form and method of manufacture
US7306812B2 (en) 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
CA2525366A1 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
TWI327915B (en) * 2003-06-12 2010-08-01 Organon Nv Pharmaceutical composition comprising antipsychotic agent and use of the antipsychotic agent for treating patients with overweight
CA2539494C (en) * 2003-09-22 2011-12-06 Baxter International Inc. High-pressure sterilization to terminally sterilize pharmaceutical preparations and medical products
JP2007537232A (ja) * 2004-05-11 2007-12-20 ファイザー・プロダクツ・インク 非定型抗精神病薬と5−ht1b受容体拮抗薬の組合せ
GB0416861D0 (en) * 2004-07-29 2004-09-01 Quadrant Drug Delivery Ltd Composition
WO2006040314A1 (en) * 2004-10-15 2006-04-20 Pfizer Inc. Treatment of bipolar disorders and associated symptoms
US7872147B2 (en) 2005-04-07 2011-01-18 N. V. Organon Intermediate compounds for the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole
AR056306A1 (es) * 2005-04-07 2007-10-03 Organon Nv FORMA CRISTALINA ORTORRoMBICA DEL MALEATO DE ASENAPINA , COMPOSICIONES FARMACÉUTICAS Y SU USO EN EL TRATAMIENTO DE TRASTORNOS MENTALES
ES2333980T3 (es) 2005-04-07 2010-03-03 N.V. Organon Compuestos intermediarios utiles en la preparacion de trans-5-cloro-2-metil-2,3,3a,12b-tetrahidro-1h-dibenzo(2,3:6,7)oxepino(4,5-c)pirrol.
US7741358B2 (en) * 2005-04-14 2010-06-22 N.V. Organon Crystal form of asenapine maleate
US7750167B2 (en) 2006-07-05 2010-07-06 N.V. Organon Process for the preparation of asenapine and intermediate products used in said process
US7875729B2 (en) 2007-01-05 2011-01-25 Synthon Bv Process for making asenapine
PE20091156A1 (es) * 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
WO2009156889A1 (en) * 2008-06-25 2009-12-30 Pfizer Inc. Diaryl compounds and uses thereof
WO2010127674A1 (en) * 2009-05-06 2010-11-11 Sunin K/S Transdermal compositions of asenapine for the treatment of psychiatric disorders
AR077225A1 (es) 2009-06-24 2011-08-10 Organon Nv Formulaciones inyectables que contienen asenapina y metodo de tratamiento que las utiliza
TW201118102A (en) 2009-07-29 2011-06-01 Organon Nv Hydroxyasenapine compounds, derivatives thereof and pharmaceutical compositions comprising same
WO2011159903A2 (en) 2010-06-18 2011-12-22 Dr. Reddy's Laboratories Ltd. Asenapine maleate
EP2598496B1 (en) 2010-07-29 2014-03-19 Laboratorios Lesvi, S.L. Novel process for the preparation of asenapine
WO2012038975A2 (en) * 2010-09-22 2012-03-29 Msn Laboratories Limited Process for the preparation of (3ars,12brs)-5-chloro-2-methyl-2,3,3a12b-tetrahydro-1hdibenzo[2,3:6,7] oxepino [4,5-c]pyrrole maleate and it's pharmaceutical composition thereof
BR112013012062B1 (pt) 2010-11-15 2020-06-02 Agenebio, Inc Composto derivado da piridazina ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica e uso do composto
WO2012066565A2 (en) 2010-11-16 2012-05-24 Cadila Healthcare Limited Asenapine maleate amorphous and crystalline form and process for preparation thereof
EP2468750A1 (en) 2010-12-13 2012-06-27 Chemo Ibérica, S.A. Polymorphic forms of asenapine maleate and processes for their preparation
WO2012123325A1 (en) 2011-03-11 2012-09-20 Medichem S.A. NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID
EP2524919A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids
EP2709615A1 (en) 2011-05-18 2014-03-26 Laboratorios Lesvi, S.L. Monoclinic crystalline form of asenapine maleate with a specific particle size distribution
JP6014656B2 (ja) 2011-05-18 2016-10-25 ラビラトリオス レスビ エス エレ 化合物の多形体
WO2013041604A1 (en) 2011-09-21 2013-03-28 Sandoz Ag Crystal form of asenapine maleate
EP2572703A1 (en) 2011-09-21 2013-03-27 Hexal AG Compressed oral dosage form for asenapine maleate
CN102657635B (zh) * 2012-05-04 2013-08-07 上海现代药物制剂工程研究中心有限公司 具有微孔的海绵状的阿塞那平舌下膜剂及其制备方法
ITMI20121810A1 (it) 2012-10-24 2014-04-25 Chemo Iberica Sa Poliformi di maleato di asenapina e processo per la loro preparazione
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2014090386A1 (en) 2012-12-11 2014-06-19 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Orally disintegrating tablet containing asenapine
RU2015128794A (ru) 2012-12-20 2017-01-25 КАШИВ ФАРМА, ЭлЭлСи Композиция перорально распадающейся таблетки, обеспечивающая повышенную биодоступность
CN103893139B (zh) * 2012-12-28 2018-06-08 石药集团中奇制药技术(石家庄)有限公司 一种阿塞那平组合物及其制备方法
CN103120688A (zh) * 2013-01-11 2013-05-29 盛世泰科生物医药技术(苏州)有限公司 一种闪释制剂的药物组合
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IN2013MU02206A (enExample) * 2013-06-28 2015-06-12 Alembic Pharmaceuticals Ltd
NZ722077A (en) 2013-12-20 2021-12-24 Agenebio Inc Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
US20170007537A1 (en) * 2014-02-18 2017-01-12 Hetero Research Foundation Pharmaceutical compositions of asenapine
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CA2987081C (en) 2015-06-11 2022-08-30 Alrise Biosystems Gmbh Process for the preparation of drug loaded microparticles
CN108026107B (zh) 2015-06-19 2021-07-30 艾吉因生物股份有限公司 用于治疗认知损害的苯并二氮杂环庚三烯衍生物、组合物和方法
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MX387784B (es) 2017-03-24 2025-03-18 Intra Celular Therapies Inc Composiciones novedosas y metodos.
EP3644973B1 (en) 2017-06-26 2021-03-24 LTS LOHMANN Therapie-Systeme AG Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer
US11980617B2 (en) 2018-03-16 2024-05-14 Intra-Cellular Therapies, Inc. Methods of treating acute depression and/or acute anxiety
CN112040940A (zh) 2018-03-23 2020-12-04 细胞内治疗公司 有机化合物
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CN112533593A (zh) 2018-06-20 2021-03-19 罗曼治疗系统股份公司 含有阿塞那平的透皮治疗系统
CN112704672A (zh) 2018-06-20 2021-04-27 罗曼治疗系统股份公司 含有阿塞那平的透皮治疗系统
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Also Published As

Publication number Publication date
ES2118584T3 (es) 1998-09-16
BR1100625A (pt) 1999-12-28
EP0746317A1 (en) 1996-12-11
NO2010024I1 (no) 2011-01-03
KR100330942B1 (ko) 2002-11-16
MX9603713A (es) 1997-12-31
CA2182981A1 (en) 1995-09-08
NO963639L (no) 1996-10-30
FI117923B (fi) 2007-04-30
JPH09509674A (ja) 1997-09-30
LU91751I2 (fr) 2011-01-04
WO1995023600A1 (en) 1995-09-08
EP0746317B1 (en) 1998-06-10
CA2182981C (en) 2006-10-17
DE69502939T2 (de) 1998-10-22
NO2010024I2 (no) 2012-04-10
JP4099224B2 (ja) 2008-06-11
DK0746317T3 (da) 1999-03-22
DE122010000050I1 (de) 2011-05-05
JP2006342178A (ja) 2006-12-21
HUT76319A (en) 1997-08-28
JP4616810B2 (ja) 2011-01-19
FI963398A0 (fi) 1996-08-30
HU225051B1 (en) 2006-05-29
DE69502939D1 (de) 1998-07-16
FR10C0056I1 (enExample) 2011-01-28
FI963398L (fi) 1996-08-30
CZ254196A3 (en) 1997-10-15
HU9602383D0 (en) 1996-10-28
NO963639D0 (no) 1996-08-30
ATE167057T1 (de) 1998-06-15
HK1008417A1 (en) 1999-05-07
NZ282394A (en) 1997-12-19
NO308772B1 (no) 2000-10-30
PL180465B1 (pl) 2001-02-28
DE122010000050I2 (de) 2011-07-21
CN1079670C (zh) 2002-02-27
CZ284633B6 (cs) 1999-01-13
RU2139051C1 (ru) 1999-10-10
US5763476A (en) 1998-06-09
AU1947895A (en) 1995-09-18
BR9506924A (pt) 1997-09-30
PL316080A1 (en) 1996-12-23
AU692530B2 (en) 1998-06-11
CN1143320A (zh) 1997-02-19

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