ATE167057T1 - Sublinguales oder bukkales arzneimittel - Google Patents

Sublinguales oder bukkales arzneimittel

Info

Publication number
ATE167057T1
ATE167057T1 AT95912188T AT95912188T ATE167057T1 AT E167057 T1 ATE167057 T1 AT E167057T1 AT 95912188 T AT95912188 T AT 95912188T AT 95912188 T AT95912188 T AT 95912188T AT E167057 T1 ATE167057 T1 AT E167057T1
Authority
AT
Austria
Prior art keywords
sublingual
buccal
pct
medicinal product
sec
Prior art date
Application number
AT95912188T
Other languages
English (en)
Inventor
Leonardus Petrus C Delbressine
Johannes Hubertus Wieringa
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8216678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE167057(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE167057T1 publication Critical patent/ATE167057T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95912188T 1994-03-02 1995-03-01 Sublinguales oder bukkales arzneimittel ATE167057T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94200521 1994-03-02

Publications (1)

Publication Number Publication Date
ATE167057T1 true ATE167057T1 (de) 1998-06-15

Family

ID=8216678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95912188T ATE167057T1 (de) 1994-03-02 1995-03-01 Sublinguales oder bukkales arzneimittel

Country Status (23)

Country Link
US (1) US5763476A (de)
EP (1) EP0746317B1 (de)
JP (2) JP4099224B2 (de)
KR (1) KR100330942B1 (de)
CN (1) CN1079670C (de)
AT (1) ATE167057T1 (de)
AU (1) AU692530B2 (de)
BR (2) BR9506924A (de)
CA (1) CA2182981C (de)
CZ (1) CZ284633B6 (de)
DE (2) DE122010000050I2 (de)
DK (1) DK0746317T3 (de)
ES (1) ES2118584T3 (de)
FI (1) FI117923B (de)
FR (1) FR10C0056I2 (de)
HK (1) HK1008417A1 (de)
HU (1) HU225051B1 (de)
LU (1) LU91751I2 (de)
NO (2) NO308772B1 (de)
NZ (1) NZ282394A (de)
PL (1) PL180465B1 (de)
RU (1) RU2139051C1 (de)
WO (1) WO1995023600A1 (de)

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RS51341B (en) 2005-04-07 2011-02-28 N.V. Organon INTERMEDIATE COMPOUNDS FOR THE TRANS-5-CHLOR-2-METHYL-2,3A, 12B-TETRAHYDRO-1H-DIBENZE [2,3; 6,7] OXEPINO [4,5-C] Pyrrole
US7872147B2 (en) 2005-04-07 2011-01-18 N. V. Organon Intermediate compounds for the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole
SI1710245T1 (sl) * 2005-04-07 2007-12-31 Organon Nv Kristalna oblika asenapin maleata
US7741358B2 (en) 2005-04-14 2010-06-22 N.V. Organon Crystal form of asenapine maleate
US7750167B2 (en) 2006-07-05 2010-07-06 N.V. Organon Process for the preparation of asenapine and intermediate products used in said process
US7875729B2 (en) 2007-01-05 2011-01-25 Synthon Bv Process for making asenapine
UY31531A1 (es) * 2007-12-17 2009-08-03 Sales derivadas de 8-oxoadenina composiciones farmacéuticas que las contienen y su uso en terapia como moduladores de receptor tipo toll (tlr)
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WO2010127674A1 (en) * 2009-05-06 2010-11-11 Sunin K/S Transdermal compositions of asenapine for the treatment of psychiatric disorders
JP5801295B2 (ja) 2009-06-24 2015-10-28 メルク・シャープ・エンド・ドーム・ベー・フェー アセナピンを含有する注射可能な配合物およびそれを用いた処置方法
TW201118102A (en) 2009-07-29 2011-06-01 Organon Nv Hydroxyasenapine compounds, derivatives thereof and pharmaceutical compositions comprising same
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WO2012013766A1 (en) 2010-07-29 2012-02-02 Laboratorios Lesvi, S.L. Novel process for the preparation of asenapine
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CA2818025A1 (en) 2010-11-15 2012-05-24 Agenebio, Inc. Pyridazine derivatives, compositions and methods for treating cognitive impairment
WO2012066565A2 (en) 2010-11-16 2012-05-24 Cadila Healthcare Limited Asenapine maleate amorphous and crystalline form and process for preparation thereof
EP2468750A1 (de) 2010-12-13 2012-06-27 Chemo Ibérica, S.A. Polymorphe Formen von Asenapinmaleat und Verfahren zur ihrer Herstellung
WO2012123325A1 (en) 2011-03-11 2012-09-20 Medichem S.A. NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID
EP2524919A1 (de) 2011-05-17 2012-11-21 Sandoz AG Neue kristalline Salze von Asenapin mit organischen Di-Säuren und Tri-Säuren
US9505771B2 (en) * 2011-05-18 2016-11-29 Laboratories Lesvi S.L. Stable micronised monoclin form of asenapine maleate and its synthesis
US9533994B2 (en) 2011-05-18 2017-01-03 Laboratorios Lesvi S.L. Monoclinic crystalline form of asenapine maleate with a specific particle size distribution
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ITMI20121810A1 (it) 2012-10-24 2014-04-25 Chemo Iberica Sa Poliformi di maleato di asenapina e processo per la loro preparazione
EP2919788A4 (de) 2012-11-14 2016-05-25 Univ Johns Hopkins Verfahren und zusammensetzungen zur behandlung von schizophrenie
US9597291B2 (en) 2012-12-11 2017-03-21 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Orally disintegrating tablet containing asenapine
WO2014100418A2 (en) 2012-12-20 2014-06-26 Kashiv Pharma, Llc Orally disintegrating tablet formulation for enhanced bioavailability
CN103893139B (zh) * 2012-12-28 2018-06-08 石药集团中奇制药技术（石家庄）有限公司 一种阿塞那平组合物及其制备方法
CN103120688A (zh) * 2013-01-11 2013-05-29 盛世泰科生物医药技术(苏州)有限公司 一种闪释制剂的药物组合
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US11033512B2 (en) 2017-06-26 2021-06-15 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer
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KR20210022656A (ko) 2018-06-20 2021-03-03 에르테에스 로만 테라피-시스테메 아게 아세나핀을 함유하는 경피 치료 시스템
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Also Published As

Publication number Publication date
HK1008417A1 (en) 1999-05-07
MX9603713A (es) 1997-12-31
FR10C0056I2 (de) 2011-11-25
WO1995023600A1 (en) 1995-09-08
DK0746317T3 (da) 1999-03-22
DE122010000050I1 (de) 2011-05-05
NZ282394A (en) 1997-12-19
JP2006342178A (ja) 2006-12-21
DE69502939T2 (de) 1998-10-22
FI963398A0 (fi) 1996-08-30
PL316080A1 (en) 1996-12-23
NO2010024I2 (no) 2012-04-10
CN1143320A (zh) 1997-02-19
EP0746317A1 (de) 1996-12-11
NO2010024I1 (no) 2011-01-03
JPH09509674A (ja) 1997-09-30
FI117923B (fi) 2007-04-30
BR1100625A (pt) 1999-12-28
CA2182981A1 (en) 1995-09-08
CN1079670C (zh) 2002-02-27
RU2139051C1 (ru) 1999-10-10
DE69502939D1 (de) 1998-07-16
NO963639L (no) 1996-10-30
KR100330942B1 (ko) 2002-11-16
HU9602383D0 (en) 1996-10-28
LU91751I2 (fr) 2011-01-04
DE122010000050I2 (de) 2011-07-21
CZ254196A3 (en) 1997-10-15
FR10C0056I1 (de) 2011-01-28
AU692530B2 (en) 1998-06-11
US5763476A (en) 1998-06-09
JP4099224B2 (ja) 2008-06-11
FI963398A (fi) 1996-08-30
CA2182981C (en) 2006-10-17
BR9506924A (pt) 1997-09-30
NO308772B1 (no) 2000-10-30
NO963639D0 (no) 1996-08-30
PL180465B1 (pl) 2001-02-28
EP0746317B1 (de) 1998-06-10
CZ284633B6 (cs) 1999-01-13
AU1947895A (en) 1995-09-18
JP4616810B2 (ja) 2011-01-19
HU225051B1 (en) 2006-05-29
ES2118584T3 (es) 1998-09-16
HUT76319A (en) 1997-08-28

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