IL109076A0 - Imidazolo-quinoxalinones, their preparation and pharmaceutical compositions containing them - Google Patents

Imidazolo-quinoxalinones, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL109076A0
IL109076A0 IL10907694A IL10907694A IL109076A0 IL 109076 A0 IL109076 A0 IL 109076A0 IL 10907694 A IL10907694 A IL 10907694A IL 10907694 A IL10907694 A IL 10907694A IL 109076 A0 IL109076 A0 IL 109076A0
Authority
IL
Israel
Prior art keywords
preparation
quinoxalinones
imidazolo
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL10907694A
Other versions
IL109076A (en
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4329970A external-priority patent/DE4329970A1/en
Application filed by Basf Ag filed Critical Basf Ag
Publication of IL109076A0 publication Critical patent/IL109076A0/en
Publication of IL109076A publication Critical patent/IL109076A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Abstract

Described are imidazoloquinoxalinones of the formula (I) in which A and R1 to R6 are as defined in the description, plus their preparation. The compounds described can be used in the preparation of drugs for use in the treatment of neurodegenerative ailments and neurotoxic disorders of the central nervous system as well as in the preparation of spasmolytics, anti-epileptics, anxiolytics and anti-depressants.
IL109076A 1993-03-31 1994-03-22 2-SUBSTITUTED 4,5-DIHYDROIMIDAZOLO £1,2-a| QUINOXALIN-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IL109076A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4310521 1993-03-31
DE4329970A DE4329970A1 (en) 1993-03-31 1993-09-04 New imidazolo-quinoxalinones, their manufacture and use

Publications (2)

Publication Number Publication Date
IL109076A0 true IL109076A0 (en) 1994-06-24
IL109076A IL109076A (en) 1997-06-10

Family

ID=25924528

Family Applications (1)

Application Number Title Priority Date Filing Date
IL109076A IL109076A (en) 1993-03-31 1994-03-22 2-SUBSTITUTED 4,5-DIHYDROIMIDAZOLO £1,2-a| QUINOXALIN-4-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (17)

Country Link
EP (1) EP0691970B1 (en)
JP (1) JPH08508271A (en)
CN (1) CN1041928C (en)
AT (1) ATE173263T1 (en)
AU (1) AU6428294A (en)
BR (1) BR9406034A (en)
CA (1) CA2158167A1 (en)
CZ (1) CZ246495A3 (en)
FI (1) FI954614A0 (en)
HR (1) HRP940210A2 (en)
HU (1) HUT73970A (en)
IL (1) IL109076A (en)
NO (1) NO953892D0 (en)
NZ (1) NZ263552A (en)
PL (1) PL310950A1 (en)
SI (1) SI9420023A (en)
WO (1) WO1994022865A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021842A1 (en) * 1994-02-11 1995-08-17 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
FR2722789B1 (en) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa IMIDAZO (1,2-A) INDENO (1,2-E) PYRAZINE-2-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
IT1276167B1 (en) * 1995-11-24 1997-10-27 Foscama Biomed Chim Farma IMIDAZO (1,2-ALPHA) QUINOSSALIN-4-AMINE ACTIVE AS ADENOSINE ANTAGONISTS, PROCEDURE FOR THEIR PREPARATION AND COMPOSITIONS
FR2743363A1 (en) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5H, 10H-IMIDAZO (1,2-A) INDENO (1,2-E) PYRAZINE-A-ONES SUBSTITUTED IN POSITION 2, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
US6271418B1 (en) * 2000-02-22 2001-08-07 Nippon Kayaku Co., Ltd. Process for preparing (hetero) aromatic substituted benzene derivatives
GB0017518D0 (en) 2000-07-17 2000-08-30 Merck Sharp & Dohme Therapeutic agents
GB0018473D0 (en) 2000-07-27 2000-09-13 Merck Sharp & Dohme Therapeutic agents
CN100386326C (en) * 2003-10-22 2008-05-07 中国人民解放军军事医学科学院毒物药物研究所 1-methylolimidazole [1,2-alpha] quinoxaline compound and its application
CN101553491B (en) * 2006-12-13 2013-05-29 Aska制药株式会社 Quinoxaline derivative
FR2921927B1 (en) * 2007-10-03 2012-10-12 Univ De Montpellier 1 IMIDAZO® 1,2-A! QUINOXALINS AND DERIVATIVES FOR THE TREATMENT OF CANCER

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2043064B (en) * 1979-02-09 1983-04-13 Roussel Lab Ltd Oximidazoquinoxaline derivatives
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
US5182386A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands

Also Published As

Publication number Publication date
HU9502848D0 (en) 1995-11-28
BR9406034A (en) 1996-01-02
FI954614A (en) 1995-09-28
EP0691970B1 (en) 1998-11-11
HRP940210A2 (en) 1996-12-31
AU6428294A (en) 1994-10-24
SI9420023A (en) 1996-04-30
CN1041928C (en) 1999-02-03
NZ263552A (en) 1997-06-24
WO1994022865A1 (en) 1994-10-13
NO953892L (en) 1995-09-29
EP0691970A1 (en) 1996-01-17
JPH08508271A (en) 1996-09-03
IL109076A (en) 1997-06-10
NO953892D0 (en) 1995-09-29
PL310950A1 (en) 1996-01-08
CZ246495A3 (en) 1996-03-13
CN1120336A (en) 1996-04-10
ATE173263T1 (en) 1998-11-15
HUT73970A (en) 1996-10-28
CA2158167A1 (en) 1994-10-13
FI954614A0 (en) 1995-09-28

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Legal Events

Date Code Title Description
HK Corrigendum

Free format text: JOURNAL NO. 3/97 PAGE 740 IN THE NOTICE UNDER SECTION 26 OF THE PATENTS LAW 5727-1967 IN RELATION TO PATENT APPLICATION NO. 109076: THE DETAILS OF THE SECOND PRIORITY CLAIM ARE: P4329970.9 4.9.1993 DE

FF Patent granted
KB Patent renewed
RH Patent void