FR06C0014I2 - - Google Patents

Info

Publication number
FR06C0014I2
FR06C0014I2 FR06C0014C FR06C0014C FR06C0014I2 FR 06C0014 I2 FR06C0014 I2 FR 06C0014I2 FR 06C0014 C FR06C0014 C FR 06C0014C FR 06C0014 C FR06C0014 C FR 06C0014C FR 06C0014 I2 FR06C0014 I2 FR 06C0014I2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR06C0014C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Publication of FR06C0014I1 publication Critical patent/FR06C0014I1/fr
Application granted granted Critical
Publication of FR06C0014I2 publication Critical patent/FR06C0014I2/fr
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR06C0014C 1995-03-27 2006-04-04 Active FR06C0014I2 (enrdf_load_html_response)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9503549 1995-03-27
PCT/FR1996/000448 WO1996030010A2 (fr) 1995-03-27 1996-03-26 Utilisation du fumagillol et ses derives pour preparer les medicaments destines a combattre les infections intestinales

Publications (2)

Publication Number Publication Date
FR06C0014I1 FR06C0014I1 (enrdf_load_html_response) 2006-11-17
FR06C0014I2 true FR06C0014I2 (enrdf_load_html_response) 2006-12-29

Family

ID=9477436

Family Applications (1)

Application Number Title Priority Date Filing Date
FR06C0014C Active FR06C0014I2 (enrdf_load_html_response) 1995-03-27 2006-04-04

Country Status (25)

Country Link
US (1) US5900431A (enrdf_load_html_response)
EP (1) EP0817626B1 (enrdf_load_html_response)
JP (1) JP3260378B2 (enrdf_load_html_response)
KR (1) KR100286920B1 (enrdf_load_html_response)
CN (1) CN1072485C (enrdf_load_html_response)
AP (1) AP646A (enrdf_load_html_response)
AT (1) ATE172641T1 (enrdf_load_html_response)
AU (1) AU706161B2 (enrdf_load_html_response)
CA (1) CA2216623C (enrdf_load_html_response)
CZ (1) CZ286821B6 (enrdf_load_html_response)
DE (1) DE69600879T2 (enrdf_load_html_response)
DK (1) DK0817626T3 (enrdf_load_html_response)
EA (1) EA000150B1 (enrdf_load_html_response)
ES (1) ES2128846T3 (enrdf_load_html_response)
FR (1) FR06C0014I2 (enrdf_load_html_response)
HU (1) HU224028B1 (enrdf_load_html_response)
IS (1) IS2048B (enrdf_load_html_response)
NO (1) NO315968B1 (enrdf_load_html_response)
NZ (1) NZ304906A (enrdf_load_html_response)
OA (1) OA10515A (enrdf_load_html_response)
PL (1) PL183378B1 (enrdf_load_html_response)
SK (1) SK283883B6 (enrdf_load_html_response)
TR (1) TR199701048T1 (enrdf_load_html_response)
UA (1) UA41446C2 (enrdf_load_html_response)
WO (1) WO1996030010A2 (enrdf_load_html_response)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0817626T3 (da) * 1995-03-27 1999-07-12 Assist Publ Hopitaux De Paris Anvendelse af fumagillol og derivater deraf til fremstilling af lægemidler mod tarminfektioner
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
EP1156829B1 (fr) * 1999-02-26 2007-05-09 Sanofi-Aventis Formulation stable contenant de la fumagilline
JP3265394B1 (ja) * 2001-03-14 2002-03-11 泰三 矢野 アクリル系樹脂手袋
DE10341887A1 (de) * 2003-09-09 2005-03-31 Leopold Kostal Gmbh & Co. Kg Elektrisches Schaltermodul
FR2886855B1 (fr) * 2005-06-08 2009-07-17 Agronomique Inst Nat Rech Utilisation de la fumagilline et de ses derives pour augmenter la biodisponibilite des lactones macrocyliques
US8399512B2 (en) * 2007-11-28 2013-03-19 Mersana Therapeutics, Inc. Biocompatible biodegradable fumagillin analog conjugates
US8865746B2 (en) * 2008-07-18 2014-10-21 Zafgen, Inc. Methods of treating an overweight or obese subject
WO2010065877A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Methods of treating an overweight or obese subject
WO2010065883A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Method of treating an overweight or obese subject
KR20120083905A (ko) 2009-10-09 2012-07-26 자프겐 코포레이션 비만의 치료에 사용하기 위한 설폰 화합물
US8815309B2 (en) 2010-01-08 2014-08-26 Zafgen, Inc. Methods of treating a subject with benign prostate hyperplasia
KR101696960B1 (ko) 2010-01-08 2017-01-16 자프겐 인크. 푸마길롤 타입 화합물 및 그의 제조 및 사용 방법
US20130266578A1 (en) 2010-04-07 2013-10-10 Thomas E. Hughes Methods of treating an overweight subject
KR20130043207A (ko) 2010-07-22 2013-04-29 자프겐 인크. 트리시클릭 화합물 및 이의 제조 및 사용 방법
PH12013500934A1 (en) 2010-11-09 2022-10-24 Zafgen Inc Crystalline solids of a metap-2 inhibitor and methods of making and using same
EP2646016B1 (en) 2010-11-29 2017-05-17 Zafgen, Inc. Treatment if obesity using non-daily administration of 6-0-(4-dimethylaminoethoxy)cinnamoyl fumagillol
MX344238B (es) 2011-01-26 2016-12-07 Zafgen Inc Compuestos de tetrazol y métodos para preparar y usar los mismos.
KR101875988B1 (ko) 2011-03-08 2018-07-06 자프겐 인크. 옥사스피로[2.5]옥탄 유도체 및 유사체
EP2705035B1 (en) 2011-05-06 2016-12-14 Zafgen, Inc. Tricyclic pyrazole sulfonamide compounds and methods of making and using same
AU2012253757B2 (en) 2011-05-06 2017-04-13 Zafgen Inc. Partially saturated tricyclic compounds and methods of making and using same
CA2835195A1 (en) 2011-05-06 2012-11-15 Zafgen, Inc. Tricyclic sulfonamide compounds and methods of making and using same
EP2763671A2 (en) 2011-10-03 2014-08-13 Zafgen, Inc. Methods of treating age related disorders
CA2861390A1 (en) 2012-01-18 2013-07-25 Zafgen, Inc. Tricyclic sulfonamide compounds and methods of making and using same
US9440943B2 (en) 2012-01-18 2016-09-13 Zafgen, Inc. Tricyclic sulfone compounds and methods of making and using same
EP2847176A1 (en) 2012-05-07 2015-03-18 Zafgen, Inc. Polymorphic salt of the oxalate salt of 6 - o - ( 4 - dimethylaminoethoxy) cinnarnoyl fumagillol and methods of making and using same
EP2846792B1 (en) 2012-05-08 2018-08-15 Zafgen, Inc. Treating hypothalamic obesity with metap2 inhibitors
CN104364251B (zh) 2012-05-09 2017-02-22 扎夫根股份有限公司 烟曲霉醇型化合物及其制备和使用方法
CA2890343A1 (en) 2012-11-05 2014-05-08 Zafgen, Inc. Tricyclic compounds useful in the treatment of liver disorders
KR20150079952A (ko) 2012-11-05 2015-07-08 자프겐 인크. 트리시클릭 화합물 및 그의 제조 및 사용 방법
BR112015010223A2 (pt) 2012-11-05 2017-07-11 Zafgen Inc compostos tricíclicos para o uso no tratamento e/ou controle de obesidade
JP2016513722A (ja) 2013-03-14 2016-05-16 ザフゲン,インコーポレイテッド 腎臓病及び他の疾患の治療方法
AR105671A1 (es) 2015-08-11 2017-10-25 Zafgen Inc Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso
CN106432255A (zh) 2015-08-11 2017-02-22 扎夫根公司 烟曲霉素醇螺环化合物和制备和使用其的方法
CN106591389B (zh) * 2015-10-15 2019-10-11 中国科学院微生物研究所 一种利用烟曲霉菌生产烟曲霉素的方法
CN105622593B (zh) * 2016-02-25 2018-06-26 中国农业科学院蜜蜂研究所 一种烟曲霉素的提取方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2791530A (en) * 1953-08-31 1957-05-07 Abbott Lab Stabilized fumagillin compositions
JPH0629278B2 (ja) * 1985-06-26 1994-04-20 藤沢薬品工業株式会社 オキサスピロオクタン化合物
US5135920A (en) * 1988-11-16 1992-08-04 Takeda Chemical Industries, Ltd. Angiostatic agents
WO1992002240A2 (en) * 1990-07-27 1992-02-20 Repligen Corporation Novel methods and compositions for treatment of angiogenic diseases
US5328930A (en) 1993-03-01 1994-07-12 Emory University Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin
DK0817626T3 (da) * 1995-03-27 1999-07-12 Assist Publ Hopitaux De Paris Anvendelse af fumagillol og derivater deraf til fremstilling af lægemidler mod tarminfektioner
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
CA2210600A1 (en) * 1996-07-17 1998-01-17 Takashi Houkan Inhibitor of tumor metastasis or recurrence
WO1998005293A2 (en) * 1996-08-02 1998-02-12 The Children's Medical Center Corporation Method of regulating the female reproductive system through angiogenesis inhibitors

Also Published As

Publication number Publication date
KR100286920B1 (ko) 2001-04-16
ATE172641T1 (de) 1998-11-15
DE69600879T2 (de) 1999-06-02
SK130797A3 (en) 1998-03-04
UA41446C2 (uk) 2001-09-17
CA2216623A1 (en) 1996-10-03
MX9707150A (es) 1998-07-31
IS2048B (is) 2005-09-15
WO1996030010A2 (fr) 1996-10-03
NZ304906A (en) 1999-06-29
AP9701092A0 (en) 1997-10-31
ES2128846T3 (es) 1999-05-16
FR06C0014I1 (enrdf_load_html_response) 2006-11-17
HUP9801220A2 (hu) 1999-09-28
NO974466L (no) 1997-09-26
JP3260378B2 (ja) 2002-02-25
EA199700267A1 (ru) 1998-04-30
EP0817626A2 (fr) 1998-01-14
CZ304997A3 (en) 1997-12-17
HUP9801220A3 (en) 2001-10-29
IS4557A (is) 1997-09-11
AP646A (en) 1998-04-27
US5900431A (en) 1999-05-04
CZ286821B6 (en) 2000-07-12
JPH11506421A (ja) 1999-06-08
DK0817626T3 (da) 1999-07-12
EP0817626B1 (fr) 1998-10-28
OA10515A (fr) 2002-04-24
PL183378B1 (pl) 2002-06-28
AU706161B2 (en) 1999-06-10
WO1996030010A3 (fr) 1996-11-28
HU224028B1 (hu) 2005-05-30
CA2216623C (en) 2005-05-31
KR19980703271A (ko) 1998-10-15
TR199701048T1 (xx) 1998-01-21
AU5278696A (en) 1996-10-16
CN1179715A (zh) 1998-04-22
NO315968B1 (no) 2003-11-24
SK283883B6 (sk) 2004-04-06
PL322470A1 (en) 1998-02-02
EA000150B1 (ru) 1998-10-29
DE69600879D1 (de) 1998-12-03
NO974466D0 (no) 1997-09-26
CN1072485C (zh) 2001-10-10

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