FI970271L - Puolisynteettiset taksaanit, joilla on kasvaimenvastainen vaikutus - Google Patents

Puolisynteettiset taksaanit, joilla on kasvaimenvastainen vaikutus Download PDF

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Publication number
FI970271L
FI970271L FI970271A FI970271A FI970271L FI 970271 L FI970271 L FI 970271L FI 970271 A FI970271 A FI 970271A FI 970271 A FI970271 A FI 970271A FI 970271 L FI970271 L FI 970271L
Authority
FI
Finland
Prior art keywords
semi
antitumor activity
synthetic taxanes
taxanes
synthetic
Prior art date
Application number
FI970271A
Other languages
English (en)
Swedish (sv)
Other versions
FI970271A0 (fi
FI120398B (fi
Inventor
Ezio Bombardelli
Bellis Paolo De
Bruno Gabetta
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI941592A external-priority patent/IT1274356B/it
Priority claimed from IT95RM000413A external-priority patent/IT1278108B1/it
Application filed by Indena Spa filed Critical Indena Spa
Publication of FI970271A0 publication Critical patent/FI970271A0/fi
Publication of FI970271L publication Critical patent/FI970271L/fi
Application granted granted Critical
Publication of FI120398B publication Critical patent/FI120398B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
FI970271A 1994-07-26 1997-01-23 Puolisynteettiset taksaanit, joilla on kasvaimia torjuvaa vaikutusta, sekä niiden valmistusmenetelmät, välituotteet ja farmaseuttiset koostumukset FI120398B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
ITMI941592A IT1274356B (it) 1994-07-26 1994-07-26 Tassani semisintetici odtati di attivita' antitumorale
ITMI941592 1994-07-26
ITRM950413 1995-06-19
IT95RM000413A IT1278108B1 (it) 1995-06-19 1995-06-19 Secotassani dotati di attivita' antitumorale.
EP9502896 1995-07-21
PCT/EP1995/002896 WO1996003394A1 (en) 1994-07-26 1995-07-21 Semi-synthetic taxanes with anti-tumoural activity

Publications (3)

Publication Number Publication Date
FI970271A0 FI970271A0 (fi) 1997-01-23
FI970271L true FI970271L (fi) 1997-03-19
FI120398B FI120398B (fi) 2009-10-15

Family

ID=26331178

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970271A FI120398B (fi) 1994-07-26 1997-01-23 Puolisynteettiset taksaanit, joilla on kasvaimia torjuvaa vaikutusta, sekä niiden valmistusmenetelmät, välituotteet ja farmaseuttiset koostumukset

Country Status (23)

Country Link
US (1) US5756776A (fi)
EP (1) EP0773938B1 (fi)
JP (1) JP2986550B2 (fi)
KR (1) KR100220490B1 (fi)
CN (4) CN1073105C (fi)
AT (1) ATE176464T1 (fi)
AU (1) AU684218B2 (fi)
BG (1) BG62851B1 (fi)
CA (1) CA2195844C (fi)
CZ (1) CZ293076B6 (fi)
DE (1) DE69507702T2 (fi)
DK (1) DK0773938T3 (fi)
ES (1) ES2126919T3 (fi)
FI (1) FI120398B (fi)
GR (1) GR3029309T3 (fi)
HU (1) HU222496B1 (fi)
NO (1) NO315116B1 (fi)
PL (1) PL187579B1 (fi)
RO (2) RO116549B1 (fi)
RU (1) RU2134688C1 (fi)
SI (1) SI9520078B (fi)
SK (1) SK281526B6 (fi)
WO (1) WO1996003394A1 (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6395770B1 (en) * 1995-10-26 2002-05-28 Baker Norton Pharmaceuticals, Inc. Method and compositions for administering taxanes orally to human patients
FR2745814B1 (fr) * 1996-03-06 1998-04-03 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0868422A1 (de) * 1996-09-24 1998-10-07 Marigen S.A. Ultramikroemulsionen aus spontan dispergierbaren konzentraten mit antitumoral und antiviral wirksamen estern von baccatin-iii-verbindungen
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
US5977386A (en) * 1996-12-24 1999-11-02 Bristol-Myers Squibb Company 6-thio-substituted paclitaxels
US5902822A (en) * 1997-02-28 1999-05-11 Bristol-Myers Squibb Company 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US6017935A (en) * 1997-04-24 2000-01-25 Bristol-Myers Squibb Company 7-sulfur substituted paclitaxels
KR100615783B1 (ko) * 1997-05-27 2006-08-25 아이박스 리서치 인코포레이티드 탁산 치료를 받고 있는 인체를 제외한 포유동물의 과민증 또는 알러지 반응을 경감시키기 위한 방법 및 약학적 키트
IT1308636B1 (it) * 1999-03-02 2002-01-09 Indena Spa Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
IT1317731B1 (it) * 2000-01-18 2003-07-15 Indena Spa Tassani semisintetici con attivita' antitumorale ed antiangiogenetica.
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
EP1129991A1 (de) * 2000-03-02 2001-09-05 Degussa AG Verfahren zur Herstellung eines titanhaltigen Zeolithen
US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
HN2005000054A (es) * 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
US20060189679A1 (en) * 2005-02-14 2006-08-24 Florida State University Research Foundation, Inc. C10 cyclopropyl ester substituted taxane compositions
ITMI20050415A1 (it) * 2005-03-15 2006-09-16 Indena Spa Derivati tassanici semi-sintetici ad attivita' antitumorale
ITMI20062479A1 (it) * 2006-12-21 2008-06-22 Indena Spa Processo per la preparazione di secotassani
CA2696856A1 (en) * 2007-08-22 2009-02-26 6570763 Canada Inc. Process for converting 9-dihydro-13-acetylbaccatin iii into docetaxel or paclitaxel
JP2011517455A (ja) * 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン
KR101671537B1 (ko) 2008-08-11 2016-11-01 넥타르 테라퓨틱스 다분지형 중합체 알카노에이트 컨쥬게이트
WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
US20130338216A1 (en) * 2010-12-22 2013-12-19 Nektar Therapeutics Deuterated and/or fluorinated taxane derivatives
US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
WO2012088391A1 (en) * 2010-12-22 2012-06-28 Nektar Therapeutics Non-ring hydroxy substituted taxanes and methods for synthesizing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
KR930702323A (ko) * 1991-07-17 1993-09-08 하지메 나까가와 항종양 활성을 가진 화합물(nsc-lsc1) 및 그의 제조방법
US5399726A (en) * 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
FR2688499B1 (fr) * 1992-03-10 1994-05-06 Rhone Poulenc Rorer Sa Procede de preparation de la beta-phenylisoserine et de ses analogues.
US5200534A (en) * 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
FR2698363B1 (fr) * 1992-11-23 1994-12-30 Rhone Poulenc Rorer Sa Nouveaux dérivés du taxane, leur préparation et les compositions qui les contiennent.

Also Published As

Publication number Publication date
US5756776A (en) 1998-05-26
DE69507702D1 (de) 1999-03-18
JP2986550B2 (ja) 1999-12-06
SK10097A3 (en) 1997-08-06
BG101165A (en) 1997-08-29
ATE176464T1 (de) 1999-02-15
WO1996003394A1 (en) 1996-02-08
FI970271A0 (fi) 1997-01-23
CZ293076B6 (cs) 2004-02-18
PL187579B1 (pl) 2004-08-31
SK281526B6 (sk) 2001-04-09
NO315116B1 (no) 2003-07-14
CA2195844C (en) 2001-10-09
CN1308073A (zh) 2001-08-15
CN1073105C (zh) 2001-10-17
AU684218B2 (en) 1997-12-04
HK1011687A1 (en) 1999-07-16
EP0773938A1 (en) 1997-05-21
FI120398B (fi) 2009-10-15
SI9520078B (sl) 1998-12-31
RU2134688C1 (ru) 1999-08-20
CA2195844A1 (en) 1996-02-08
DE69507702T2 (de) 1999-08-26
CZ19997A3 (en) 1997-07-16
SI9520078A (en) 1997-06-30
RO115875B1 (ro) 2000-07-28
BG62851B1 (bg) 2000-09-29
CN1154109A (zh) 1997-07-09
KR100220490B1 (ko) 1999-09-15
JPH09512827A (ja) 1997-12-22
CN1332163A (zh) 2002-01-23
HUT76829A (en) 1997-11-28
ES2126919T3 (es) 1999-04-01
RO116549B1 (ro) 2001-03-30
CN1130356C (zh) 2003-12-10
GR3029309T3 (en) 1999-05-28
CN1120161C (zh) 2003-09-03
CN1128795C (zh) 2003-11-26
AU3164195A (en) 1996-02-22
NO970296D0 (no) 1997-01-23
CN1308072A (zh) 2001-08-15
HU222496B1 (hu) 2003-07-28
PL318289A1 (en) 1997-06-09
NO970296L (no) 1997-03-12
DK0773938T3 (da) 1999-09-20
EP0773938B1 (en) 1999-02-03

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