IT1278108B1 - Secotassani dotati di attivita' antitumorale. - Google Patents
Secotassani dotati di attivita' antitumorale.Info
- Publication number
- IT1278108B1 IT1278108B1 IT95RM000413A ITRM950413A IT1278108B1 IT 1278108 B1 IT1278108 B1 IT 1278108B1 IT 95RM000413 A IT95RM000413 A IT 95RM000413A IT RM950413 A ITRM950413 A IT RM950413A IT 1278108 B1 IT1278108 B1 IT 1278108B1
- Authority
- IT
- Italy
- Prior art keywords
- secotaxanes
- activity
- tumoural activity
- tumoural
- cytotoxic
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical group NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
- YWLXLRUDGLRYDR-ZHPRIASZSA-N 5beta,20-epoxy-1,7beta,10beta,13alpha-tetrahydroxy-9-oxotax-11-ene-2alpha,4alpha-diyl 4-acetate 2-benzoate Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](O)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 YWLXLRUDGLRYDR-ZHPRIASZSA-N 0.000 abstract 1
- 231100000433 cytotoxic Toxicity 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical class O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Landscapes
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (29)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95RM000413A IT1278108B1 (it) | 1995-06-19 | 1995-06-19 | Secotassani dotati di attivita' antitumorale. |
| KR1019970700442A KR100220490B1 (ko) | 1994-07-26 | 1995-07-21 | 항암작용을 갖는 반합성 탁산유도체 |
| EP95927699A EP0773938B1 (en) | 1994-07-26 | 1995-07-21 | Semi-synthetic taxanes with anti-tumoural activity |
| CZ1997199A CZ293076B6 (cs) | 1994-07-26 | 1995-07-21 | Polosyntetické taxany, způsob jejich výroby, farmaceutické prostředky s jejich obsahem a meziprodukty pro jejich výrobu |
| AU31641/95A AU684218B2 (en) | 1994-07-26 | 1995-07-21 | Semi-synthetic taxanes with anti-tumoural activity |
| DE69507702T DE69507702T2 (de) | 1994-07-26 | 1995-07-21 | Semisynthetisch taxal derivate mit antitumor wirkung |
| ES95927699T ES2126919T3 (es) | 1994-07-26 | 1995-07-21 | Taxanos semisinteticos con actividad antitumoral. |
| AT95927699T ATE176464T1 (de) | 1994-07-26 | 1995-07-21 | Semisynthetisch taxal derivate mit antitumor wirkung |
| DK95927699T DK0773938T3 (da) | 1994-07-26 | 1995-07-21 | Semi-syntetiske taxaner med anti-tumoraktivitet |
| RU97102722A RU2134688C1 (ru) | 1994-07-26 | 1995-07-21 | Полусинтетический таксан, промежуточные соединения, способы получения и фармацевтическая композиция |
| CA002195844A CA2195844C (en) | 1994-07-26 | 1995-07-21 | Semi-synthetic taxanes with anti-tumoural activity |
| SK100-97A SK281526B6 (sk) | 1994-07-26 | 1995-07-21 | Semisyntetický taxán, spôsob jeho prípravy a medziprodukt, semisyntetický sekotaxán, spôsob jeho prípravy, farmaceutický prostriedok s ich obsahom a ich použitie |
| RO97-00125A RO115875B1 (ro) | 1994-07-26 | 1995-07-21 | Derivati de taxan, procedeu pentru prepararea acestora, intermediar pentru prepararea acestora si compozitie farmaceutica care ii contine |
| PL95318289A PL187579B1 (pl) | 1994-07-26 | 1995-07-21 | Nowe półsyntetyczne taksany, sposób wytwarzania półsyntetycznych taksanów, nowe związki pośrednie, nowe półsyntetyczne seko-taksany, sposób wytwarzania półsyntetycznych seko-taksanów i przeciwnowotworowe kompozycje farmaceutyczne |
| JP8505456A JP2986550B2 (ja) | 1994-07-26 | 1995-07-21 | 抗腫瘍活性を有する半合成タキサン |
| PCT/EP1995/002896 WO1996003394A1 (en) | 1994-07-26 | 1995-07-21 | Semi-synthetic taxanes with anti-tumoural activity |
| SI9520078A SI9520078B (sl) | 1994-07-26 | 1995-07-21 | Polsintetski taksani z antitumorsko aktivnostjo |
| CN95194333A CN1073105C (zh) | 1994-07-26 | 1995-07-21 | 具有抗肿瘤活性的半合成紫杉烷 |
| ROA200000502A RO116549B1 (ro) | 1994-07-26 | 1995-07-21 | Derivati de taxan, procedeu pentru prepararea acestora, intermediar pentru prepararea acestora si compozitie farmaceutica care ii contine |
| HU9700206A HU222496B1 (hu) | 1994-07-26 | 1995-07-21 | Félszintetikus taxánszármazékok, eljárás ezek előállítására, valamint ezeket tartalmazó gyógyászati készítmények |
| US08/505,924 US5756776A (en) | 1994-07-26 | 1995-07-24 | Semi-synthetic taxanes with anti-tumoural activity |
| NO19970296A NO315116B1 (no) | 1994-07-26 | 1997-01-23 | Semi-syntetiske taksaner med anti-tumoral aktivitet |
| BG101165A BG62851B1 (bg) | 1994-07-26 | 1997-01-23 | Полусинтетични таксани с противотуморно действие, метод за получаване и приложението им |
| FI970271A FI120398B (fi) | 1994-07-26 | 1997-01-23 | Puolisynteettiset taksaanit, joilla on kasvaimia torjuvaa vaikutusta, sekä niiden valmistusmenetelmät, välituotteet ja farmaseuttiset koostumukset |
| HK98112903A HK1011687A1 (en) | 1994-07-26 | 1998-12-07 | Semi-synthetic taxanes with anti-tumoural activity |
| GR990400393T GR3029309T3 (en) | 1994-07-26 | 1999-02-09 | Semi-synthetic taxanes with anti-tumoural activity |
| CN00129055A CN1130356C (zh) | 1994-07-26 | 2000-09-29 | 具有抗肿瘤活性的半合成断紫杉烷 |
| CN00129054A CN1120161C (zh) | 1994-07-26 | 2000-09-29 | 具有抗肿瘤活性的半合成紫杉烷 |
| CN00129056A CN1128795C (zh) | 1994-07-26 | 2000-09-29 | 具有抗肿瘤活性的半合成紫杉烷 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95RM000413A IT1278108B1 (it) | 1995-06-19 | 1995-06-19 | Secotassani dotati di attivita' antitumorale. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM950413A0 ITRM950413A0 (it) | 1995-06-19 |
| ITRM950413A1 ITRM950413A1 (it) | 1996-12-19 |
| IT1278108B1 true IT1278108B1 (it) | 1997-11-17 |
Family
ID=11403438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT95RM000413A IT1278108B1 (it) | 1994-07-26 | 1995-06-19 | Secotassani dotati di attivita' antitumorale. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1278108B1 (it) |
-
1995
- 1995-06-19 IT IT95RM000413A patent/IT1278108B1/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM950413A0 (it) | 1995-06-19 |
| ITRM950413A1 (it) | 1996-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |