FI965036A - Interleukiini-beta:aa muuttavan entsyymin inhibiittoreita - Google Patents

Interleukiini-beta:aa muuttavan entsyymin inhibiittoreita Download PDF

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Publication number
FI965036A
FI965036A FI965036A FI965036A FI965036A FI 965036 A FI965036 A FI 965036A FI 965036 A FI965036 A FI 965036A FI 965036 A FI965036 A FI 965036A FI 965036 A FI965036 A FI 965036A
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FI
Finland
Prior art keywords
interleukin
inhibitors
converting enzyme
beta converting
beta
Prior art date
Application number
FI965036A
Other languages
English (en)
Swedish (sv)
Other versions
FI965036A0 (fi
Inventor
Guy W Bemis
Julian M C Golec
David J Lauffer
Michael D Mullican
Mark A Murcko
David J Livingston
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/261,452 external-priority patent/US5756466A/en
Priority claimed from US08/440,898 external-priority patent/US5847135A/en
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of FI965036A0 publication Critical patent/FI965036A0/fi
Publication of FI965036A publication Critical patent/FI965036A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Paper (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
FI965036A 1994-06-17 1996-12-16 Interleukiini-beta:aa muuttavan entsyymin inhibiittoreita FI965036A (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/261,452 US5756466A (en) 1994-06-17 1994-06-17 Inhibitors of interleukin-1β converting enzyme
US08/405,581 US5656627A (en) 1994-06-17 1995-03-17 Inhibitors of interleukin-1β converting enzyme
US08/440,898 US5847135A (en) 1994-06-17 1995-05-25 Inhibitors of interleukin-1β converting enzyme
PCT/US1995/007617 WO1995035308A1 (en) 1994-06-17 1995-06-16 INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME

Publications (2)

Publication Number Publication Date
FI965036A0 FI965036A0 (fi) 1996-12-16
FI965036A true FI965036A (fi) 1997-02-14

Family

ID=27401408

Family Applications (1)

Application Number Title Priority Date Filing Date
FI965036A FI965036A (fi) 1994-06-17 1996-12-16 Interleukiini-beta:aa muuttavan entsyymin inhibiittoreita

Country Status (22)

Country Link
US (2) US5716929A (fi)
EP (1) EP0784628A1 (fi)
JP (1) JP4190029B2 (fi)
CN (1) CN1192035C (fi)
AP (1) AP797A (fi)
AU (1) AU709114B2 (fi)
BG (1) BG63634B1 (fi)
BR (1) BR9508051A (fi)
CA (1) CA2192089C (fi)
CZ (1) CZ298625B6 (fi)
FI (1) FI965036A (fi)
GE (1) GEP20012446B (fi)
HU (1) HUT76622A (fi)
IL (1) IL114015A0 (fi)
IS (1) IS4399A (fi)
MA (1) MA24511A1 (fi)
MX (1) MX9606546A (fi)
NZ (1) NZ289560A (fi)
PL (1) PL185693B1 (fi)
SK (1) SK287422B6 (fi)
TW (1) TW509698B (fi)
WO (1) WO1995035308A1 (fi)

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