FI944602A0 - Farmaseuttisesti aktiiviset bisyklis-heterosykliset amiinit - Google Patents
Farmaseuttisesti aktiiviset bisyklis-heterosykliset amiinitInfo
- Publication number
- FI944602A0 FI944602A0 FI944602A FI944602A FI944602A0 FI 944602 A0 FI944602 A0 FI 944602A0 FI 944602 A FI944602 A FI 944602A FI 944602 A FI944602 A FI 944602A FI 944602 A0 FI944602 A0 FI 944602A0
- Authority
- FI
- Finland
- Prior art keywords
- pharmaceutically active
- bicyclic heterocyclic
- heterocyclic amines
- active bicyclic
- xxx
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86364692A | 1992-04-03 | 1992-04-03 | |
PCT/US1993/002188 WO1993020078A1 (en) | 1992-04-03 | 1993-03-16 | Pharmaceutically active bicyclic-heterocyclic amines |
Publications (2)
Publication Number | Publication Date |
---|---|
FI944602A0 true FI944602A0 (fi) | 1994-10-03 |
FI944602A FI944602A (fi) | 1994-10-03 |
Family
ID=25341481
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI944602A FI944602A (fi) | 1992-04-03 | 1994-10-03 | Farmaseuttisesti aktiiviset bisyklis-heterosykliset amiinit |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0633886B1 (cs) |
JP (1) | JPH08502721A (cs) |
KR (1) | KR100284473B1 (cs) |
AT (1) | ATE197051T1 (cs) |
AU (1) | AU675932B2 (cs) |
CA (1) | CA2130937A1 (cs) |
CZ (1) | CZ236494A3 (cs) |
DE (1) | DE69329574T2 (cs) |
DK (1) | DK0633886T3 (cs) |
ES (1) | ES2150941T3 (cs) |
FI (1) | FI944602A (cs) |
GR (1) | GR3035188T3 (cs) |
HU (1) | HUT70954A (cs) |
LV (1) | LV12794B (cs) |
MX (1) | MX9301847A (cs) |
NO (1) | NO303542B1 (cs) |
PL (2) | PL175327B1 (cs) |
PT (1) | PT633886E (cs) |
RU (1) | RU2103272C1 (cs) |
SK (1) | SK119194A3 (cs) |
WO (1) | WO1993020078A1 (cs) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1177354A (zh) * | 1995-03-02 | 1998-03-25 | 法玛西雅厄普约翰美国公司 | 嘧啶并[4,5-b]吲哚 |
US6180643B1 (en) | 1996-11-19 | 2001-01-30 | Amgen Inc. | Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents |
WO1998024453A1 (fr) * | 1996-12-05 | 1998-06-11 | Nippon Shinyaku Co., Ltd. | Medicaments pour la myelopathie |
NZ336659A (en) * | 1997-01-08 | 2001-01-26 | Upjohn Co | Pharmaceutically active pyrimido[4,5-b]indoles |
GB9716657D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
GB2331988B (en) | 1997-12-04 | 2003-04-16 | Imperial College | Polycyclic sulphamate inhibitors or oestrone sulphatase |
GB9803226D0 (en) | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
US6686366B1 (en) | 1998-06-02 | 2004-02-03 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
OA12147A (en) | 1998-06-02 | 2006-05-05 | Osi Pharm Inc | PyrroloÄ2,3dÜpyrimidine compositions and their use. |
US6878716B1 (en) | 1998-06-02 | 2005-04-12 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptor and uses thereof |
PA8474101A1 (es) * | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | Compuestos de pirrolo [2,3-d] pirimidina |
CA2342855A1 (en) * | 1998-09-04 | 2000-03-16 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel pyranoses |
GB9902461D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902452D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902459D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902453D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902455D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9918035D0 (en) | 1999-07-30 | 1999-09-29 | Novartis Ag | Organic compounds |
US6664252B2 (en) | 1999-12-02 | 2003-12-16 | Osi Pharmaceuticals, Inc. | 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof |
EP1731520A1 (en) * | 1999-12-02 | 2006-12-13 | OSI Pharmaceuticals, Inc. | Pyrrolo[2,3-d]pyrimidine derivatives which are antagonists of adenosine A1, A2A, and A3 |
US6680322B2 (en) | 1999-12-02 | 2004-01-20 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptors and uses thereof |
US7160890B2 (en) | 1999-12-02 | 2007-01-09 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
US6610688B2 (en) | 1999-12-21 | 2003-08-26 | Sugen, Inc. | 4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors |
GB0000625D0 (en) | 2000-01-13 | 2000-03-01 | Zeneca Ltd | Chemical compounds |
AU2001234958A1 (en) | 2000-02-11 | 2001-08-20 | Bristol-Myers Squibb Company | Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases |
US20020061897A1 (en) | 2000-03-30 | 2002-05-23 | Elliott Richard L. | Neuropeptide Y antagonists |
AU7705601A (en) | 2000-07-25 | 2002-02-05 | Merck & Co Inc | N-substituted indoles useful in the treatment of diabetes |
SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
US6673802B2 (en) | 2000-12-01 | 2004-01-06 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
US6680324B2 (en) | 2000-12-01 | 2004-01-20 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptors and uses thereof |
GB0100622D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds V111 |
GB0117396D0 (en) | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
AU2002360436A1 (en) | 2001-11-30 | 2003-06-17 | Osi Pharmaceuticals, Inc. | 2-aryl pyrrologpyrimidines for a1 and a3 receptors |
WO2003053366A2 (en) | 2001-12-20 | 2003-07-03 | Osi Pharmaceuticals, Inc. | Pyrimidine a2b selective antagonist compounds, their synthesis and use |
CN101973998A (zh) | 2001-12-20 | 2011-02-16 | Osi药物公司 | 吡咯并嘧啶A2b选择性拮抗剂化合物 |
WO2004092170A2 (en) | 2003-04-09 | 2004-10-28 | Biogen Idec Ma Inc. | Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists |
GB0308208D0 (en) | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
EP1633756B1 (en) | 2003-04-09 | 2008-12-24 | Biogen Idec MA Inc. | A2a adenosine receptor antagonists |
WO2004092177A1 (en) | 2003-04-09 | 2004-10-28 | Biogen Idec Ma Inc. | Triazolopyrazines and methods of making and using the same |
WO2005063665A1 (en) * | 2003-12-23 | 2005-07-14 | Abraxis Bioscience, Inc | Propofol analogs, process for their preparation, and methods of use |
ZA200606792B (en) | 2004-03-04 | 2007-12-27 | Kissei Pharmaceutical | Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof |
NZ552093A (en) | 2004-06-17 | 2009-06-26 | Wyeth Corp | Processes for preparing gonadotropin releasing hormone receptor antagonists |
CA2570968A1 (en) | 2004-06-17 | 2006-01-26 | Wyeth | Gonadotropin releasing hormone receptor antagonists |
DE602005009209D1 (de) | 2004-06-18 | 2008-10-02 | Biolipox Ab | Zur behandlung von entzündungen geeignete indole |
FR2880626B1 (fr) * | 2005-01-13 | 2008-04-18 | Aventis Pharma Sa | Derives de la purine, compositions les contenant et utilisation |
JP2008527029A (ja) | 2005-01-19 | 2008-07-24 | バイオリポックス エービー | 炎症の治療に有用なインドール類 |
US7534796B2 (en) | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
FR2884824B1 (fr) | 2005-04-20 | 2007-07-13 | Sanofi Aventis Sa | Derives de 1h-pyrimido[4,5-b]indole, leur preparation et leur application en therapeutique |
US7531542B2 (en) | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
US7582636B2 (en) | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
UA95788C2 (en) | 2005-12-15 | 2011-09-12 | Ф. Хоффманн-Ля Рош Аг | Fused pyrrole derivatives |
KR100749216B1 (ko) * | 2006-08-30 | 2007-08-13 | 위아 주식회사 | 4륜구동차량용 부변속기 |
MX2009004898A (es) | 2006-11-09 | 2009-05-19 | Hoffmann La Roche | Derivados de indol y de benzofurano-2-carboxamida. |
RU2472797C2 (ru) * | 2007-08-08 | 2013-01-20 | ГЛАКСОСМИТКЛАЙН ЭлЭлСи | ПРОИЗВОДНЫЕ 2-[(2-(ФЕНИЛАМИНО)-1Н-ПИРРОЛО[2,3-d]ПИРИМИДИН-4-ИЛ)АМИНО]БЕНЗАМИДА В КАЧЕСТВЕ ИНГИБИТОРОВ IGF-1R ДЛЯ ЛЕЧЕНИЯ РАКА |
EP2178869B1 (en) * | 2007-08-17 | 2013-06-12 | LG Life Sciences Ltd. | Indole compounds as an inhibitor of cellular necrosis |
AR070127A1 (es) | 2008-01-11 | 2010-03-17 | Novartis Ag | Pirrolo - pirimidinas y pirrolo -piridinas |
KR101577943B1 (ko) | 2008-01-31 | 2015-12-16 | 사노피 | 사이클릭 아자인돌-3-카복스아미드, 이들의 제조방법 및 약제로서의 이들의 용도 |
CL2009000241A1 (es) * | 2008-02-07 | 2010-09-03 | Chugai Pharmaceutical Co Ltd | Compuestos derivados de 5-(2-morfolin-4-il-7h-pirrolo[2,3-d]pirimidin-4-il)pirimidin-2-ilamina; proceso de preparacion; composicion farmaceutica; y uso de los compuestos para tratar o prevenir una enfermedad proliferativa tal como el cancer. |
EP2382207B1 (en) * | 2008-11-11 | 2015-04-29 | Xcovery Holding Company LLC | Pi3k/mtor kinase inhibitors |
RS55662B1 (sr) | 2010-10-06 | 2017-06-30 | Glaxosmithkline Llc | Derivati benzimidazola kao inhibitori pi3 kinaze |
EP2670753B1 (en) | 2011-01-31 | 2016-10-19 | Novartis AG | Novel heterocyclic derivatives |
KR102132574B1 (ko) | 2011-03-15 | 2020-07-09 | 로렌스 리버모어 내쇼날 시큐리티, 엘엘시 | 트라이사이클릭 자이라제 억제제 |
PT2771342T (pt) | 2011-10-28 | 2016-08-17 | Novartis Ag | Derivados de purina e o seu uso no tratamento de doença |
PL2807165T3 (pl) | 2012-01-27 | 2019-09-30 | Université de Montréal | Pochodne pirymido[4,5-b]indolu i ich zastosowanie do namnażania hematopoetycznych komórek macierzystych |
PE20150153A1 (es) | 2012-06-29 | 2015-02-05 | Pfizer | 7H-PIRROLO[2,3-d]PIRIMIDINAS 4-(AMINO-SUBSTITUIDAS) NOVEDOSAS COMO INHIBIDORES DE LRRK2 |
US9695171B2 (en) | 2013-12-17 | 2017-07-04 | Pfizer Inc. | 3,4-disubstituted-1 H-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7H-pyrrolo[2,3-c]pyridazines as LRRK2 inhibitors |
SG11201607586UA (en) | 2014-03-13 | 2016-10-28 | Agency Science Tech & Res | Fused pyrimidine-based hydroxamate derivatives |
AU2015321654B2 (en) * | 2014-09-22 | 2019-10-31 | National Health Research Institutes | Heterocyclic compounds and use thereof |
CA2987974C (en) | 2015-06-05 | 2021-10-12 | Hema-Quebec | Methods for culturing and/or differentiating hematopoietic stem cells into progenitors and uses thereof |
EP3350178B1 (en) | 2015-09-14 | 2021-10-20 | Pfizer Inc. | Novel imidazo [4,5-c]quinoline and imidazo [4,5-c][1,5]naphthyridine derivatives as lrrk2 inhibitors |
US9630968B1 (en) | 2015-12-23 | 2017-04-25 | Arqule, Inc. | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof |
WO2018039310A1 (en) | 2016-08-24 | 2018-03-01 | Arqule, Inc. | Amino-pyrrolopyrimidinone compounds and methods of use thereof |
TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
BR112020015976A2 (pt) * | 2018-02-16 | 2020-12-15 | UCB Biopharma SRL | Derivados de anel 6,5 heterobicíclico farmacêutico |
US20240150358A1 (en) * | 2020-06-03 | 2024-05-09 | Kineta, Inc. | Purines and methods of their use |
WO2021263079A1 (en) * | 2020-06-26 | 2021-12-30 | Tempest Therapeutics, Inc. | Trex1 inhibitors and uses thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB864145A (en) * | 1959-06-02 | 1961-03-29 | Thomae Gmbh Dr K | Novel purines and a process for their manufacture |
GB1268772A (en) * | 1968-03-15 | 1972-03-29 | Glaxo Lab Ltd | NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME |
ATE140457T1 (de) * | 1989-09-19 | 1996-08-15 | Teijin Ltd | Pyrrolo(2,3-d>pyrimidinderivate, verfahren zur herstellung und arzneimittelzusammensetzungen die diese enthalten |
-
1993
- 1993-03-16 PL PL93317810A patent/PL175327B1/pl not_active IP Right Cessation
- 1993-03-16 DK DK93908303T patent/DK0633886T3/da active
- 1993-03-16 HU HU9402829A patent/HUT70954A/hu unknown
- 1993-03-16 RU RU94042466A patent/RU2103272C1/ru not_active IP Right Cessation
- 1993-03-16 PL PL93305430A patent/PL175347B1/pl not_active IP Right Cessation
- 1993-03-16 JP JP5517457A patent/JPH08502721A/ja active Pending
- 1993-03-16 WO PCT/US1993/002188 patent/WO1993020078A1/en not_active Application Discontinuation
- 1993-03-16 EP EP93908303A patent/EP0633886B1/en not_active Expired - Lifetime
- 1993-03-16 KR KR1019940703452A patent/KR100284473B1/ko not_active IP Right Cessation
- 1993-03-16 CA CA002130937A patent/CA2130937A1/en not_active Abandoned
- 1993-03-16 SK SK1191-94A patent/SK119194A3/sk unknown
- 1993-03-16 AU AU39174/93A patent/AU675932B2/en not_active Ceased
- 1993-03-16 DE DE69329574T patent/DE69329574T2/de not_active Expired - Fee Related
- 1993-03-16 AT AT93908303T patent/ATE197051T1/de not_active IP Right Cessation
- 1993-03-16 ES ES93908303T patent/ES2150941T3/es not_active Expired - Lifetime
- 1993-03-16 PT PT93908303T patent/PT633886E/pt unknown
- 1993-03-16 CZ CZ942364A patent/CZ236494A3/cs unknown
- 1993-03-31 MX MX9301847A patent/MX9301847A/es not_active IP Right Cessation
-
1994
- 1994-09-30 NO NO943655A patent/NO303542B1/no unknown
- 1994-10-03 FI FI944602A patent/FI944602A/fi not_active Application Discontinuation
-
2001
- 2001-01-04 GR GR20010400006T patent/GR3035188T3/el not_active IP Right Cessation
- 2001-10-18 LV LVP-01-150A patent/LV12794B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0633886B1 (en) | 2000-10-18 |
CZ236494A3 (en) | 1994-12-15 |
DK0633886T3 (da) | 2000-12-18 |
PL175347B1 (pl) | 1998-12-31 |
ES2150941T3 (es) | 2000-12-16 |
HUT70954A (en) | 1995-11-28 |
DE69329574D1 (de) | 2000-11-23 |
AU3917493A (en) | 1993-11-08 |
FI944602A (fi) | 1994-10-03 |
LV12794B (en) | 2002-06-20 |
PL175327B1 (pl) | 1998-12-31 |
EP0633886A1 (en) | 1995-01-18 |
SK119194A3 (en) | 1995-05-10 |
RU94042466A (ru) | 1996-07-20 |
LV12794A (en) | 2002-02-20 |
WO1993020078A1 (en) | 1993-10-14 |
CA2130937A1 (en) | 1993-10-14 |
ATE197051T1 (de) | 2000-11-15 |
JPH08502721A (ja) | 1996-03-26 |
GR3035188T3 (en) | 2001-04-30 |
KR950700912A (ko) | 1995-02-20 |
RU2103272C1 (ru) | 1998-01-27 |
AU675932B2 (en) | 1997-02-27 |
NO943655L (no) | 1994-12-05 |
PT633886E (pt) | 2001-03-30 |
MX9301847A (es) | 1993-10-01 |
KR100284473B1 (ko) | 2001-04-02 |
NO943655D0 (no) | 1994-09-30 |
NO303542B1 (no) | 1998-07-27 |
HU9402829D0 (en) | 1995-02-28 |
DE69329574T2 (de) | 2001-05-31 |
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