FI924553A0 - Tiofensulfonamider anvaendbara som kolanhydrasinhibitorer - Google Patents

Tiofensulfonamider anvaendbara som kolanhydrasinhibitorer

Info

Publication number
FI924553A0
FI924553A0 FI924553A FI924553A FI924553A0 FI 924553 A0 FI924553 A0 FI 924553A0 FI 924553 A FI924553 A FI 924553A FI 924553 A FI924553 A FI 924553A FI 924553 A0 FI924553 A0 FI 924553A0
Authority
FI
Finland
Prior art keywords
thiofensulphonamider
cololhydrasinhibitorer
anvaendbara som
anvaendbara
som
Prior art date
Application number
FI924553A
Other languages
English (en)
Finnish (fi)
Other versions
FI924553A (fi
Inventor
Thomas R Dean
Hwang-Hsing Chen
Jesse A May
Anura Pathmaciri Dantanarayana
Daniel Kuzmich
Paul W Zinke
Raymond Eugene Conrow
Michael E Deason
Mark Thomas Dupriest
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Publication of FI924553A0 publication Critical patent/FI924553A0/fi
Publication of FI924553A publication Critical patent/FI924553A/fi
Priority to FI963424A priority Critical patent/FI963424A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI924553A 1990-04-09 1992-10-08 Tiofensulfonamider anvaendbara som kolanhydrasinhibitorer FI924553A (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI963424A FI963424A0 (fi) 1990-04-09 1996-09-02 Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50673090A 1990-04-09 1990-04-09
US07/618,765 US5153192A (en) 1990-04-09 1990-11-27 Thiophene sulfonamides useful as carbonic anhydrase inhibitors
PCT/US1991/002262 WO1991015486A1 (en) 1990-04-09 1991-04-03 Thiophene sulfonamides useful as carbonic anydrase inhibitors

Publications (2)

Publication Number Publication Date
FI924553A0 true FI924553A0 (fi) 1992-10-08
FI924553A FI924553A (fi) 1992-10-08

Family

ID=27055558

Family Applications (2)

Application Number Title Priority Date Filing Date
FI924553A FI924553A (fi) 1990-04-09 1992-10-08 Tiofensulfonamider anvaendbara som kolanhydrasinhibitorer
FI963424A FI963424A0 (fi) 1990-04-09 1996-09-02 Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI963424A FI963424A0 (fi) 1990-04-09 1996-09-02 Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi

Country Status (20)

Country Link
US (2) US5153192A (ko)
EP (1) EP0527801B1 (ko)
JP (1) JP2562394B2 (ko)
KR (1) KR100196414B1 (ko)
AT (1) ATE221527T1 (ko)
AU (1) AU655924B2 (ko)
BR (1) BR9106330A (ko)
CA (1) CA2080223C (ko)
DE (3) DE69133080T2 (ko)
DK (1) DK0527801T3 (ko)
ES (1) ES2180530T3 (ko)
FI (2) FI924553A (ko)
HK (1) HK1014186A1 (ko)
IL (1) IL97800A (ko)
LU (2) LU90935I2 (ko)
NL (2) NL300098I2 (ko)
NO (1) NO923948L (ko)
NZ (1) NZ237754A (ko)
WO (1) WO1991015486A1 (ko)
ZA (1) ZA912580B (ko)

Families Citing this family (80)

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ES2118941T3 (es) * 1992-02-21 1998-10-01 Alcon Lab Inc Composiciones antiglaucoma topicas que comprenden inhibidores de anhidrasa carbonica y bloqueantes beta.
US5932572A (en) * 1992-02-21 1999-08-03 Alcon Laboratories, Inc. Topical anti-glaucoma compositions
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US5344929A (en) * 1993-02-18 1994-09-06 Alcon Laboratories, Inc. Preparation of carbonic anhydrase inhibitors
US5538966A (en) * 1994-01-21 1996-07-23 Alcon Laboratories, Inc. Carbonic anhydrase inhibitors
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US5646142A (en) * 1994-07-08 1997-07-08 Alcon Laboratories, Inc. Thiophene sulfonamides useful as carbonic anhydrase inhibitors
US6316443B1 (en) 1994-08-04 2001-11-13 Merck & Co., Inc. Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a β-adrenergic antagonist
US5510347A (en) * 1994-09-09 1996-04-23 Alcon Laboratories, Inc. Thienothiadiazine sulfonamides useful as carbonic anhydrase inhibitors
US5464831A (en) * 1994-09-09 1995-11-07 Alcon Laboratories, Inc. Thienothiadiazine sulfonamides useful as carbonic anhydrase inhibitors
US5470973A (en) * 1994-10-03 1995-11-28 Alcon Laboratories, Inc. Synthesis of sulfonamide intermediates
US5620970A (en) * 1995-06-05 1997-04-15 Alcon Laboratories, Inc. Topical ophthalmic carbonic anhydrase inhibitor formulations
US6172054B1 (en) 1995-06-15 2001-01-09 Alcon Laboratories, Inc. Combination therapy for lowering and controlling intraocular pressure
WO1997002825A1 (en) * 1995-07-12 1997-01-30 Alcon Laboratories, Inc. Thiophene sulfonamides useful as carbonic anhydrase inhibitors
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JP5881514B2 (ja) * 2012-04-09 2016-03-09 株式会社トクヤマ アミン誘導体の製造方法
JP5914246B2 (ja) * 2012-08-10 2016-05-11 株式会社トクヤマ ブリンゾラミドの精製方法
CN102936236A (zh) * 2012-11-13 2013-02-20 江苏吉贝尔药业有限公司 一种布林佐胺中间体(3-乙酰基-5-氯-2-(苄基巯基)噻酚)的制备方法
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EA036820B1 (ru) 2014-01-24 2020-12-23 Сентисс Фарма Прайвет Лимитед Фармацевтическая композиция, содержащая бринзоламид
US11285163B2 (en) 2014-10-20 2022-03-29 Sentiss Pharma Private Limited Ophthalmic solution
JP6192878B1 (ja) * 2015-12-10 2017-09-06 千寿製薬株式会社 眼科用医薬製品
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JP2021521240A (ja) 2018-04-25 2021-08-26 シルパ メディケア リミテッドＳｈｉｌｐａ Ｍｅｄｉｃａｒｅ Ｌｉｍｉｔｅｄ ブリンゾラミドの眼科用組成物

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DE1096916B (de) * 1957-12-17 1961-01-12 Hoechst Ag Verfahren zur Herstellung von Thiophen-3, 5-disulfonamiden
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Also Published As

Publication number Publication date
IL97800A0 (en) 1992-06-21
BR9106330A (pt) 1993-04-20
ATE221527T1 (de) 2002-08-15
NO923948D0 (no) 1992-10-09
EP0527801B1 (en) 2002-07-31
DE122009000026I1 (de) 2010-01-28
ZA912580B (en) 1992-01-29
EP0527801A4 (en) 1993-03-10
DE69133080T2 (de) 2003-03-27
WO1991015486A1 (en) 1991-10-17
US5153192A (en) 1992-10-06
NL300389I1 (nl) 2009-07-01
US5240923A (en) 1993-08-31
IL97800A (en) 1997-08-14
FI963424A (fi) 1996-09-02
NZ237754A (en) 1992-08-26
NL300098I2 (nl) 2003-01-06
ES2180530T3 (es) 2003-02-16
FI963424A0 (fi) 1996-09-02
NL300098I1 (nl) 2002-11-01
AU7746791A (en) 1991-10-30
CA2080223C (en) 2000-11-07
DE10299054I1 (de) 2006-06-08
KR930700490A (ko) 1993-03-15
AU655924B2 (en) 1995-01-19
DE69133080D1 (de) 2002-09-05
JP2562394B2 (ja) 1996-12-11
NO923948L (no) 1992-12-08
EP0527801A1 (en) 1993-02-24
DK0527801T3 (da) 2002-11-25
JPH05508832A (ja) 1993-12-09
FI924553A (fi) 1992-10-08
LU91555I2 (fr) 2009-06-22
CA2080223A1 (en) 1991-10-10
KR100196414B1 (ko) 1999-06-15
HK1014186A1 (en) 1999-09-24
LU90935I2 (en) 2002-09-05

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