FI891650A - Menetelmä oraalisen, hapossa pysymätöntä bentsimidatsolijohdannaista sisältävän valmisteen valmistamiseksi - Google Patents

Menetelmä oraalisen, hapossa pysymätöntä bentsimidatsolijohdannaista sisältävän valmisteen valmistamiseksi Download PDF

Info

Publication number
FI891650A
FI891650A FI891650A FI891650A FI891650A FI 891650 A FI891650 A FI 891650A FI 891650 A FI891650 A FI 891650A FI 891650 A FI891650 A FI 891650A FI 891650 A FI891650 A FI 891650A
Authority
FI
Finland
Prior art keywords
acid
preparation
benzimidazole derivative
layer
oral
Prior art date
Application number
FI891650A
Other languages
English (en)
Swedish (sv)
Other versions
FI93422C (fi
FI93422B (fi
FI891650A0 (fi
Inventor
Yasuharu Saeki
Noritoshi Koyama
Sumio Watanabe
Shigeru Aoki
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of FI891650A0 publication Critical patent/FI891650A0/fi
Publication of FI891650A publication Critical patent/FI891650A/fi
Application granted granted Critical
Publication of FI93422B publication Critical patent/FI93422B/fi
Publication of FI93422C publication Critical patent/FI93422C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
FI891650A 1988-05-18 1989-04-06 Menetelmä oraalisen, hapossa pysymätöntä bentsimidatsolijohdannaista sisältävän valmisteen valmistamiseksi FI93422C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12123388 1988-05-18
JP63121233A JPH0768125B2 (ja) 1988-05-18 1988-05-18 酸不安定化合物の内服用製剤

Publications (4)

Publication Number Publication Date
FI891650A0 FI891650A0 (fi) 1989-04-06
FI891650A true FI891650A (fi) 1989-11-19
FI93422B FI93422B (fi) 1994-12-30
FI93422C FI93422C (fi) 1995-04-10

Family

ID=14806208

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891650A FI93422C (fi) 1988-05-18 1989-04-06 Menetelmä oraalisen, hapossa pysymätöntä bentsimidatsolijohdannaista sisältävän valmisteen valmistamiseksi

Country Status (14)

Country Link
US (1) US5035899A (fi)
EP (1) EP0342522B1 (fi)
JP (1) JPH0768125B2 (fi)
KR (1) KR910002641B1 (fi)
AT (1) ATE70442T1 (fi)
CA (1) CA1336958C (fi)
DD (1) DD283771A5 (fi)
DE (1) DE68900566D1 (fi)
DK (1) DK174664B1 (fi)
ES (1) ES2051919T3 (fi)
FI (1) FI93422C (fi)
GR (1) GR3003389T3 (fi)
HU (1) HU203200B (fi)
NO (1) NO178135C (fi)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
YU48263B (sh) * 1991-06-17 1997-09-30 Byk Gulden Lomberg Chemische Fabrik Gmbh. Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola
US6764697B1 (en) * 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
EP0571973B1 (en) * 1992-05-29 2000-02-02 Nikken Chemicals Co., Ltd. Slow-release sodium valproate tablets
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
HUT78132A (hu) * 1994-07-08 2000-06-28 Astra Aktiebolag Omeprazol magnéziumsóját tartalmazó új orális gyógyszerforma
ES2094694B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5945124A (en) * 1995-07-05 1999-08-31 Byk Gulden Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
US6296876B1 (en) 1997-10-06 2001-10-02 Isa Odidi Pharmaceutical formulations for acid labile substances
FR2774288B1 (fr) * 1998-01-30 2001-09-07 Ethypharm Sa Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques
WO1999055158A1 (en) * 1998-04-30 1999-11-04 Sepracor Inc. S-rabeprazole compositions and methods
US6174902B1 (en) 1999-04-28 2001-01-16 Sepracor Inc. R-rabeprazole compositions and methods
FR2793688B1 (fr) 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
SK285247B6 (sk) 1999-06-07 2006-09-07 Altana Pharma Ag Dávková forma acidolabilných účinných zlúčenín, jednotka účinnej zlúčeniny, spôsob jej výroby a mikrosféra
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
ES2168043B1 (es) * 1999-09-13 2003-04-01 Esteve Labor Dr Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido.
DE19959419A1 (de) 1999-12-09 2001-06-21 Ratiopharm Gmbh Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung
AU2001296908A1 (en) * 2000-09-29 2002-04-08 Geneva Pharmaceuticals, Inc. Proton pump inhibitor formulation
JP2002234842A (ja) * 2001-02-09 2002-08-23 Kyowa Yakuhin Kogyo Kk 内服腸溶性製剤
US20030190360A1 (en) * 2001-03-13 2003-10-09 Baichwal Anand R. Chronotherapeutic dosage forms containing glucocorticosteroid and methods of treatment
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US20050163846A1 (en) * 2001-11-21 2005-07-28 Eisai Co., Ltd. Preparation composition containing acid-unstable physiologically active compound, and process for producing same
DE10211289A1 (de) * 2002-03-14 2003-09-25 Basf Ag Kombination von Polyvinylacetat von wasserunlöslichen, säureunlöslichen oder alkaliunlöslichen Polymeren zur Hestellung von Filmüberzügen mit sehr kontrollierter Freisetzung und hoher Stabilität
US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
US20040028737A1 (en) * 2002-08-12 2004-02-12 Kopran Research Laboratories Limited Enteric coated stable oral pharmaceutical composition of acid unstable drug and process for preparing the same
JP2004231520A (ja) * 2003-01-28 2004-08-19 Nichiko Pharmaceutical Co Ltd 保存安定性及び溶出速度に優れた医薬組成物
US20040146558A1 (en) * 2003-01-28 2004-07-29 Kyowa Pharmaceutical Co., Ltd. Oral enteric-coated preparation
CL2004000983A1 (es) 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
PE20050150A1 (es) 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
EP2112920B1 (en) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US20050042277A1 (en) * 2003-07-17 2005-02-24 Irukulla Srinivas Pharmaceutical compositions having a swellable coating
US20050147663A1 (en) * 2003-07-17 2005-07-07 Mohan Mailatur S. Method of treatment for improved bioavailability
JP2007505129A (ja) * 2003-09-11 2007-03-08 グリュコン テクノロジーズ グループ エルエルシー （−）−ヒドロキシクエン酸の腸溶性送達物
EP1663156A2 (en) * 2003-09-19 2006-06-07 Penwest Pharmaceuticals Company Chronotherapeutic dosage forms
NZ545921A (en) * 2003-09-19 2009-09-25 Penwest Pharmaceuticals Co Delayed released dosage forms
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
CA2547398A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating
JP2007517038A (ja) * 2003-12-30 2007-06-28 ドクター レディズ ラボラトリーズ リミテッド 薬学的組成物
KR100794078B1 (ko) * 2004-03-26 2008-01-10 에자이 알앤드디 매니지먼트 가부시키가이샤 용출 제어 제제 및 그의 제조 방법
CA2561700A1 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060024362A1 (en) * 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
BRPI0518396A2 (pt) * 2004-12-27 2008-11-18 Eisai R&D Man Co Ltd mÉtodo para estabilizaÇço de droga anti-demÊncia
US20060160852A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Composition containing anti-dementia drug
WO2006085335A2 (en) * 2005-01-03 2006-08-17 Lupin Limited Pharmaceutical composition of acid labile substances
US7991169B2 (en) * 2005-06-29 2011-08-02 Analog Devices, Inc. Charge/discharge control circuit for audio device
US20090148519A1 (en) * 2005-09-29 2009-06-11 Yasuhiro Zaima Pulsed-release preparation having improved disintegration properties in vivo
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
JP2009523784A (ja) * 2006-01-16 2009-06-25 ジュビラント・オルガノシス・リミテッド 酸不安定化合物の安定な医薬製剤およびその製造方法
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
GB2459393B (en) 2006-10-05 2010-09-08 Santarus Inc Novel capsule formulation for the proton pump inhibitor omeprazole
WO2008062320A2 (en) * 2006-10-06 2008-05-29 Eisai R&D Management Co., Ltd Extended release formulations of a proton pump inhibitor
MX2009004475A (es) 2006-10-27 2009-08-12 Univ Missouri Composiciones que comprenden agentes acido labiles que inhiben la bomba de protones, por lo menos otro agente farmaceuticamente activo y metodos de uso de las misma.
JPWO2009069280A1 (ja) 2007-11-27 2011-04-07 大原薬品工業株式会社 造粒物の製造法
SI22806A (sl) * 2008-06-23 2009-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalinične oblike natrijevega rabeprazola
CH699302B1 (de) * 2008-08-11 2012-03-15 Mepha Gmbh Orale pharmazeutische Formulierung für Omeprazol, enthaltend eine spezifische Trennschicht.
JP2012502015A (ja) * 2008-09-09 2012-01-26 アストラゼネカ・アクチエボラーグ 必要がある患者に医薬組成物を送達するための方法
US20100093747A1 (en) * 2008-10-10 2010-04-15 Erica Brook Goodhew Method of inducing negative chemotaxis
EA201290026A1 (ru) 2009-06-25 2012-07-30 Астразенека Аб Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid)
WO2010151697A1 (en) * 2009-06-25 2010-12-29 Pozen Inc. Method for treating a patient in need of aspirin therapy
CN102805733B (zh) * 2011-06-01 2016-03-09 日东电工株式会社 颗粒制剂及其制造方法
JP2015500326A (ja) 2011-12-16 2015-01-05 アトピックス テラピューティクス リミテッド 好酸球性食道炎の治療のためのｃｒｔｈ２拮抗薬およびプロトンポンプ阻害薬の組み合わせ
WO2013101897A2 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
CA2903375C (en) * 2013-03-01 2020-11-24 Bpsi Holdings, Llc. Delayed release film coatings containing calcium silicate and substrates coated therewith
JP6344678B2 (ja) * 2013-09-27 2018-06-20 キョーリンリメディオ株式会社 テルミサルタン含有製剤及びその製造方法
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi

Also Published As

Publication number Publication date
HUT51896A (en) 1990-06-28
NO891935D0 (no) 1989-05-12
FI93422C (fi) 1995-04-10
DK174664B1 (da) 2003-08-18
CA1336958C (en) 1995-09-12
US5035899A (en) 1991-07-30
EP0342522A1 (en) 1989-11-23
KR890016964A (ko) 1989-12-14
DE68900566D1 (de) 1992-01-30
GR3003389T3 (en) 1993-02-17
NO891935L (no) 1989-11-20
DK239189A (da) 1989-11-19
JPH01290628A (ja) 1989-11-22
ATE70442T1 (de) 1992-01-15
HU203200B (en) 1991-06-28
FI93422B (fi) 1994-12-30
EP0342522B1 (en) 1991-12-18
ES2051919T3 (es) 1994-07-01
JPH0768125B2 (ja) 1995-07-26
DD283771A5 (de) 1990-10-24
NO178135C (no) 1996-01-31
DK239189D0 (da) 1989-05-17
FI891650A0 (fi) 1989-04-06
NO178135B (no) 1995-10-23
KR910002641B1 (ko) 1991-04-27

Similar Documents

Publication Publication Date Title
FI93422B (fi) Menetelmä oraalisen, hapossa pysymätöntä bentsimidatsolijohdannaista sisältävän valmisteen valmistamiseksi
FI101889B1 (fi) Menetelmä partikkelikoostumuksen valmistamiseksi, joka sisältää polymeerimateriaalia sisältäviä partikkeleita
SE8600402L (sv) Forfarande for behandling av doseringsformer
FI101344B1 (fi) Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseuttisesti aktiivista ainetta
SE8902336L (sv) Foerfarande och anordning foer maskinbelaeggningstorkning av en pappersbana eller liknande
KR890015366A (ko) 반도체 박막형성법
CA2081921A1 (en) Improvements in or relating to electrostatic coating of substrates of medicinal products
FI20040479A (fi) 3-aminopiperidiinijohdannaisia ja menetelmiä niiden valmistamiseksi
FI891135A0 (fi) Menetelmä materiaaliradan kuivaamiseksi ja laitteisto menetelmän toteuttamiseksi
FI901565A0 (fi) Laite ja menetelmä radioaktiivisen aineen koteloimiseksi
FI823420A0 (fi) Enteriska mikrokapslar och foerfarande foer deras framstaellning
ATE29392T1 (de) Herstellung eines feinteiligen materials und verkapselung.
FI851785L (fi) Menetelmä suojapäällysteen muodostamiseksi loisteaineosasille ja loisteaineosanen
ATE132544T1 (de) Keramisches material und verfahren zu dessen herstellung
NO893390L (no) Fremgangsmaate for fremstilling av partikler som inneholder biologisk produsert materiale.
NO910023L (no) Fremgangsmaate til fremstilling av en film inneholdende lanthankromittpartikler.
FI92387B (fi) Menetelmä 3,4-difluorisubstituoidun benseenin valmistamiseksi
DE69014090T2 (de) Wärmehärtendes Überzugsmittel und Herstellung eines pigmentierten Films.
DE69221048D1 (de) Verfahren zur Herstellung eines Gelatine enthaltenden Aufzeichnungsmaterials
NO903004D0 (no) Fremgangsmaate for hvittoning av papirbestrykningsmasser samt hvittoningspreparater for fremgangsmaaten.
DE58906823D1 (de) Implantat.
KR900700271A (ko) 폴리페닐렌술피드 필름, 그 제조방법 및 그 진공증착방법
NO179233C (no) Fremgangsmåte for fremstilling av et fast preparat for oral tilförsel omfattende en eller flere katekolforbindelser
FI892291A (fi) Menetelmä lääkeaineina käyttökelpoisten 6-fenoksimetyyli-4-hydroksitetrahydropyran-2-onien ja 6-tiofenoksimetyyli-4-hydroksitetrahydropyran-2-onien sekä vastaavien dihydroksikarboksyylihappojohdannaisten, suolojen ja estereiden valmistamiseksi
SE8801492D0 (sv) Forfarande for framstellning av en mantel till en behallare och anordning for genomforande av detta forfarande

Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: EISAI CO., LTD.

MA Patent expired