ES2051919T3 - Preparado para via oral de un compuesto de un acido inestable. - Google Patents

Preparado para via oral de un compuesto de un acido inestable.

Info

Publication number
ES2051919T3
ES2051919T3 ES89108492T ES89108492T ES2051919T3 ES 2051919 T3 ES2051919 T3 ES 2051919T3 ES 89108492 T ES89108492 T ES 89108492T ES 89108492 T ES89108492 T ES 89108492T ES 2051919 T3 ES2051919 T3 ES 2051919T3
Authority
ES
Spain
Prior art keywords
acid
composite
prepared
oral use
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89108492T
Other languages
English (en)
Inventor
Yasuharu Saeki
Noritoshi Koyama
Sumio Watanabe
Shigeru Aoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ES2051919T3 publication Critical patent/ES2051919T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

LA PREPARACION PERORAL DE UN COMPUESTO ACIDO INESTABLE COMPRENDE (I) UN NUCLEO QUE CONTENGA EL COMPUESTO ACIDO INESTABLE, (II) UNA PRIMERA CAPA REVESTIDA SOBRE EL NUCLEO, QUE COMPRENDA UN MATERIAL SOLUBLE EN AGUA Y DEPOSITADOR DE UNA PELICULA Y PARTICULAS FINAS DE UNA SUBSTANCIA SOLUBLE EN AGUA, SUSPENDIDAS EN EL MATERIAL Y (III) UNA SEGUNDA CAPA, REVESTIDA SOBRE LA PRIMERA CAPA DE UNA PELICULA ENTERICA. EL COMPUESTO ACIDO INESTABLE ES UN COMPUESTO DE BENZIMIDAZOL.
ES89108492T 1988-05-18 1989-05-11 Preparado para via oral de un compuesto de un acido inestable. Expired - Lifetime ES2051919T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63121233A JPH0768125B2 (ja) 1988-05-18 1988-05-18 酸不安定化合物の内服用製剤

Publications (1)

Publication Number Publication Date
ES2051919T3 true ES2051919T3 (es) 1994-07-01

Family

ID=14806208

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89108492T Expired - Lifetime ES2051919T3 (es) 1988-05-18 1989-05-11 Preparado para via oral de un compuesto de un acido inestable.

Country Status (14)

Country Link
US (1) US5035899A (es)
EP (1) EP0342522B1 (es)
JP (1) JPH0768125B2 (es)
KR (1) KR910002641B1 (es)
AT (1) ATE70442T1 (es)
CA (1) CA1336958C (es)
DD (1) DD283771A5 (es)
DE (1) DE68900566D1 (es)
DK (1) DK174664B1 (es)
ES (1) ES2051919T3 (es)
FI (1) FI93422C (es)
GR (1) GR3003389T3 (es)
HU (1) HU203200B (es)
NO (1) NO178135C (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2094694A1 (es) * 1995-02-01 1997-01-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.

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JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2094694A1 (es) * 1995-02-01 1997-01-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.

Also Published As

Publication number Publication date
HUT51896A (en) 1990-06-28
NO891935D0 (no) 1989-05-12
FI93422C (fi) 1995-04-10
DK174664B1 (da) 2003-08-18
CA1336958C (en) 1995-09-12
US5035899A (en) 1991-07-30
EP0342522A1 (en) 1989-11-23
KR890016964A (ko) 1989-12-14
DE68900566D1 (de) 1992-01-30
GR3003389T3 (en) 1993-02-17
NO891935L (no) 1989-11-20
DK239189A (da) 1989-11-19
JPH01290628A (ja) 1989-11-22
ATE70442T1 (de) 1992-01-15
HU203200B (en) 1991-06-28
FI93422B (fi) 1994-12-30
EP0342522B1 (en) 1991-12-18
JPH0768125B2 (ja) 1995-07-26
DD283771A5 (de) 1990-10-24
FI891650A (fi) 1989-11-19
NO178135C (no) 1996-01-31
DK239189D0 (da) 1989-05-17
FI891650A0 (fi) 1989-04-06
NO178135B (no) 1995-10-23
KR910002641B1 (ko) 1991-04-27

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