ES2059729T5 - Preparado farmaceutico de liberacion controlada y metodo para producir el mismo. - Google Patents

Preparado farmaceutico de liberacion controlada y metodo para producir el mismo.

Info

Publication number
ES2059729T5
ES2059729T5 ES89302767T ES89302767T ES2059729T5 ES 2059729 T5 ES2059729 T5 ES 2059729T5 ES 89302767 T ES89302767 T ES 89302767T ES 89302767 T ES89302767 T ES 89302767T ES 2059729 T5 ES2059729 T5 ES 2059729T5
Authority
ES
Spain
Prior art keywords
same
pharmaceutical preparation
produce
polymeric substance
controlled liberation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89302767T
Other languages
English (en)
Other versions
ES2059729T3 (es
Inventor
Masayoshi Samejima
Kazuo Noda
Yoshiyuki Hirakawa
Hiroyuki Yoshino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13722933&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2059729(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of ES2059729T3 publication Critical patent/ES2059729T3/es
Application granted granted Critical
Publication of ES2059729T5 publication Critical patent/ES2059729T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

SE EXPLICA UNA PREPARACION FARMACEUTICA DE LIBERACION SOSTENIDA, QUE COMPRENDE UN NUCLEO QUE CONTIENE EL PRINCIPIO ACTIVO FARMACEUTICO, Y UNA PELICULA POROSA DE UNA SUSTANCIA POLIMERICA HIDROFOBICA O UNA SUSTANCIA POLIMERICA HIDROBFOBICA Y UNA SUSTANCIA POLIMERICA HIDROFILICA, EL NUCLEO SE RECUBRE CON LA MEMBRANA POROSA. TAMBIEN SE EXPLICA EL METODO PARA SU OBTENCION.
ES89302767T 1988-03-31 1989-03-21 Preparado farmaceutico de liberacion controlada y metodo para producir el mismo. Expired - Lifetime ES2059729T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8060488 1988-03-31

Publications (2)

Publication Number Publication Date
ES2059729T3 ES2059729T3 (es) 1994-11-16
ES2059729T5 true ES2059729T5 (es) 2002-09-16

Family

ID=13722933

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89302767T Expired - Lifetime ES2059729T5 (es) 1988-03-31 1989-03-21 Preparado farmaceutico de liberacion controlada y metodo para producir el mismo.

Country Status (21)

Country Link
US (1) US5068112A (es)
EP (1) EP0335560B2 (es)
KR (1) KR950007202B1 (es)
AT (1) ATE91888T1 (es)
AU (1) AU610711B2 (es)
BG (1) BG50712A3 (es)
CA (1) CA1339078C (es)
DE (1) DE68907762T3 (es)
DK (1) DK156289A (es)
ES (1) ES2059729T5 (es)
FI (1) FI101344B1 (es)
FR (1) FR2629344B1 (es)
HK (1) HK76195A (es)
HU (1) HU201882B (es)
IE (1) IE64348B1 (es)
IL (1) IL89695A0 (es)
NO (1) NO178136C (es)
PH (1) PH25791A (es)
PT (1) PT90153B (es)
RU (1) RU1836083C (es)
ZA (1) ZA892131B (es)

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FI101344B1 (fi) † 1988-03-31 1998-06-15 Tanabe Seiyaku Co Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseuttisesti aktiivista ainetta
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KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
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US5160742A (en) * 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
US6913767B1 (en) 1993-10-25 2005-07-05 Genentech, Inc. Compositions for microencapsulation of antigens for use as vaccines
US6080429A (en) * 1993-10-25 2000-06-27 Genentech, Inc. Method for drying microspheres
US5523095A (en) * 1993-12-15 1996-06-04 Eastman Chemical Company Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends
US5536505A (en) * 1993-12-15 1996-07-16 Eastman Chemical Company Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
ES2120354B1 (es) * 1996-02-12 1999-07-01 Univ Sevilla Dispositivo terapeutico para direccionar farmacos hacia el tramo del tracto gastrointestinal deseado en funcion de las caracteristicas fisicoquimicas del mismo.
DE19628776A1 (de) * 1996-07-17 1998-01-22 Bayer Ag Oral applizierbare Granulate von Hexahydropyrazinderivaten
US20030100532A1 (en) * 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
BR9802915A (pt) * 1997-09-12 2000-01-11 Oscar Gold Procedimento para formar composições farmaceuticas em pilulas ou granulos substancialmente esfericos, de ação controlada e continuada, contendo como agente ativo o (7-bromo-1,3-diidro-5-(2-piridninilo)-2h-1,4-benzodiazep ina-2(1h)-um)
CA2309321A1 (en) 1997-11-10 1999-05-20 G.D. Searle & Co. Use of alkylated iminosugars to treat multidrug resistance
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
ES2272054T3 (es) 1998-02-12 2007-04-16 United Therapeutics Corporation Uso de compuestos de n-sustituido-1,5-didesoxi-1,5-imino-d-glucitol para tratar infecciones por el virus de la hepatitis.
CA2327685C (en) 1998-04-03 2008-11-18 Bm Research A/S Controlled release composition
EP1173161A2 (en) 1999-02-12 2002-01-23 G.D. SEARLE & CO. Glucamine compounds for treating hepatitis virus infections
US6545021B1 (en) * 1999-02-12 2003-04-08 G.D. Searle & Co. Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
SE9903879D0 (sv) * 1999-10-28 1999-10-28 Ethical Pharmaceuticals Sweden Multipor food protection
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CA2398555C (en) 2000-01-27 2008-04-22 Tanabe Seiyaku Co., Ltd. Sustained release preparation and method for producing the same
CN1422156A (zh) * 2000-02-14 2003-06-04 法马西亚公司 N－取代的－1,5－二脱氧－1,5－亚氨基－d－葡萄糖醇化合物在治疗肝炎病毒感染中的用途
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
GB0106953D0 (en) * 2001-03-20 2001-05-09 Univ Aberdeen Neufofibrillary labels
US20040253310A1 (en) 2001-09-21 2004-12-16 Gina Fischer Morphine polymer release system
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
US20040208936A1 (en) * 2002-07-22 2004-10-21 Roland Chorin Novel compositions
US20040151772A1 (en) * 2002-11-08 2004-08-05 Egalet A/S Controlled release carvedilol compositions
EP1607092A4 (en) * 2003-03-17 2010-12-15 Takeda Pharmaceutical CONTROLLED RELEASE COMPOSITIONS
CA2520312C (en) 2003-03-26 2013-06-18 Egalet A/S Matrix compositions for controlled delivery of drug substances
ATE495732T1 (de) 2003-03-26 2011-02-15 Egalet As Morphin-system mit kontrollierter freisetzung
US7115283B2 (en) * 2003-05-06 2006-10-03 Access Business Group International Llc Preparations for sustained release of nutraceuticals and methods of controllably releasing nutraceuticals
EP1479383B1 (en) * 2003-05-20 2006-10-04 Ethypharm Oral sustained release pharmaceutical composition
FR2855412B1 (fr) * 2003-05-27 2007-05-25 Menvielle Bourg Fabienn Joanny Composition a liberation prolongee de magnesium, et son application dans le domaine therapeutique, cosmetique et nutritionnel
WO2004112746A1 (en) * 2003-06-26 2004-12-29 Korea Research Institute Of Chemical Technology Controlled release-drug delivery system for oral administration
JPWO2005011637A1 (ja) * 2003-08-04 2006-09-14 エーザイ株式会社 用時分散型製剤
KR100615952B1 (ko) 2004-05-27 2006-08-28 한국화학연구원 서방형 약물 전달 시스템
AU2006254554B2 (en) * 2005-06-03 2011-11-24 Egalet Ltd A solid pharmaceutical composition with a first fraction of a dispersion medium and a second fraction of a matrix, the latter being at least partially first exposed to gastrointestinal fluids
RU2309732C1 (ru) 2006-03-13 2007-11-10 Олег Ильич Эпштейн Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата
ATE525065T1 (de) * 2006-07-10 2011-10-15 Pfleger R Chem Fab Pharmazeutische zubereitung für die orale verabreichung mit gesteuerter wirkstofffreisetzung im dünndarm und verfahren zu ihrer herstellung
EP2104493A2 (en) * 2007-01-16 2009-09-30 Egalet A/S Use of i) a polyglycol and n) an active drug substance for the preparation of a pharmaceutical composition for i) mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse
WO2008094877A2 (en) * 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
US8679541B2 (en) * 2007-03-14 2014-03-25 Particle Dynamics International, Llc Spatial arrangement of particles in a drinking device for oral delivery of pharmaceuticals
EP2155167A2 (en) 2007-06-04 2010-02-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
CN101801350A (zh) 2007-08-13 2010-08-11 阿巴斯迪特宁医药有限公司 抗滥用药物、使用方法和制备方法
FR2931359B1 (fr) * 2008-05-20 2012-12-21 Menvielle Bourg Fabienne Joanny Utilisation d'une matrice pour administration orale de magnesium a liberation prolongee, et composition contenant cette matrice
FR2931361B1 (fr) * 2008-05-20 2012-08-31 Menvielle Bourg Fabienne Joanny Systeme a base de magnesium et son utilisation en cosmetique
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
NZ603579A (en) 2009-06-24 2014-02-28 Egalet Ltd Controlled release formulations
DE112011102358T5 (de) 2010-07-15 2013-04-25 Oleg Iliich Epshtein Verfahren zur Erhöhung der Wirkung einer aktivierten-potenzierten Form eines Antikörpers
CA2877183A1 (en) 2012-07-06 2014-01-09 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
WO2014146093A2 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration

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Also Published As

Publication number Publication date
NO891052D0 (no) 1989-03-13
HK76195A (en) 1995-05-26
AU610711B2 (en) 1991-05-23
KR890014095A (ko) 1989-10-21
IL89695A0 (en) 1989-09-28
PH25791A (es) 1991-11-05
FI891163A0 (fi) 1989-03-10
DE68907762T3 (de) 2003-11-20
IE64348B1 (en) 1995-07-26
FR2629344A1 (fr) 1989-10-06
NO178136B (no) 1995-10-23
NO178136C (no) 1996-01-31
EP0335560A2 (en) 1989-10-04
IE891006L (en) 1989-09-30
US5068112A (en) 1991-11-26
DE68907762T2 (de) 1993-11-11
CA1339078C (en) 1997-07-29
ES2059729T3 (es) 1994-11-16
PT90153B (pt) 1994-07-29
RU1836083C (ru) 1993-08-23
FR2629344B1 (fr) 1994-09-16
FI101344B (fi) 1998-06-15
NO891052L (no) 1989-10-02
KR950007202B1 (ko) 1995-07-04
EP0335560A3 (en) 1990-12-27
DK156289D0 (da) 1989-03-30
HUT50050A (en) 1989-12-28
FI101344B1 (fi) 1998-06-15
DE68907762D1 (de) 1993-09-02
AU3227389A (en) 1989-10-05
BG50712A3 (en) 1992-10-15
EP0335560B1 (en) 1993-07-28
EP0335560B2 (en) 2002-01-23
ZA892131B (en) 1989-11-29
DK156289A (da) 1989-10-01
PT90153A (pt) 1989-11-10
ATE91888T1 (de) 1993-08-15
FI891163A (fi) 1989-10-01
HU201882B (en) 1991-01-28

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