|
IN165717B
(cs)
*
|
1986-08-07 |
1989-12-23 |
Battelle Memorial Institute |
|
|
US5529932A
(en)
*
|
1988-01-28 |
1996-06-25 |
Pharmacia, S.P.A. |
Isolated DNA encoding a plant ribosome inactivating protein from the leaves of saponaria officinalis
|
|
FI102355B
(fi)
*
|
1988-02-11 |
1998-11-30 |
Squibb Bristol Myers Co |
Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjug aattien valmistamiseksi
|
|
DE4004573A1
(de)
*
|
1989-02-17 |
1990-08-23 |
Tanabe Seiyaku Co |
Neues versuchstier und seine herstellung
|
|
US5354844A
(en)
*
|
1989-03-16 |
1994-10-11 |
Boehringer Ingelheim International Gmbh |
Protein-polycation conjugates
|
|
US5576288A
(en)
*
|
1989-04-27 |
1996-11-19 |
The Salk Institute For Biological Studies |
Fibroblast growth factor conjugates
|
|
US5191067A
(en)
*
|
1989-04-27 |
1993-03-02 |
The Salk Institute For Biological Studies |
Fibroblast growth factor conjugates
|
|
IL95031A
(en)
|
1989-07-18 |
2007-03-08 |
Amgen Inc |
Method for the production of a human recombinant tumor necrosis factor inhibitor
|
|
AU638043B2
(en)
*
|
1989-07-20 |
1993-06-17 |
Novartis Ag |
Labeled polypeptide derivatives
|
|
US5208323A
(en)
*
|
1989-08-10 |
1993-05-04 |
Universite Laval |
Coupling of an anti-tumor to an antibody using glutaraldehyde preactivated anti-tumor agent
|
|
US6329508B1
(en)
|
1989-09-07 |
2001-12-11 |
Alkermes, Inc. |
Transferrin receptor reactive chimeric antibodies
|
|
US5672683A
(en)
*
|
1989-09-07 |
1997-09-30 |
Alkermes, Inc. |
Transferrin neuropharmaceutical agent fusion protein
|
|
US5182107A
(en)
*
|
1989-09-07 |
1993-01-26 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates
|
|
US5527527A
(en)
*
|
1989-09-07 |
1996-06-18 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical agent conjugates
|
|
US5977307A
(en)
*
|
1989-09-07 |
1999-11-02 |
Alkermes, Inc. |
Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins
|
|
CA2070416A1
(en)
*
|
1989-10-23 |
1991-04-24 |
Richard Ingram |
Polypeptide inhibitors of gamma interferon
|
|
EP0517829B2
(en)
*
|
1990-03-02 |
2007-12-26 |
Boston Medical Center Corporation |
Improved chimeric toxins
|
|
US6552170B1
(en)
|
1990-04-06 |
2003-04-22 |
Amgen Inc. |
PEGylation reagents and compounds formed therewith
|
|
US5137877B1
(en)
*
|
1990-05-14 |
1996-01-30 |
Bristol Myers Squibb Co |
Bifunctional linking compounds conjugates and methods for their production
|
|
ES2068587T3
(es)
*
|
1990-05-30 |
1995-04-16 |
Deutsches Krebsforsch |
Medicamentos tumorales sustituidos con polieter.
|
|
IL98528A0
(en)
*
|
1990-06-21 |
1992-07-15 |
Merck & Co Inc |
Pharmaceutical compositions containing hybrid for killing bladder cancer cells
|
|
CA2086679A1
(en)
*
|
1990-07-05 |
1992-01-06 |
Hermanus A. M. Verheul |
Receptor directed-toxin conjugates
|
|
US5478804A
(en)
*
|
1990-09-19 |
1995-12-26 |
The Salk Institute For Biological Studies |
Treatment of tumorigenic pathophysiological conditions with FGF-cytoxic conjugates
|
|
AU8730691A
(en)
*
|
1990-09-28 |
1992-04-28 |
Neorx Corporation |
Polymeric carriers for release of covalently linked agents
|
|
US5431899A
(en)
*
|
1991-02-04 |
1995-07-11 |
University Of Saskatchewan |
Rotavirus VP6 as a diagnostic and targeting agent
|
|
US5464753A
(en)
*
|
1991-03-08 |
1995-11-07 |
Univ Illinois |
Purification and manipulation of bone marrow and blood cells on the basis of P-glycoprotein expression
|
|
ATE240740T1
(de)
*
|
1991-03-15 |
2003-06-15 |
Amgen Inc |
Pegylation von polypeptiden
|
|
WO1992020371A1
(en)
*
|
1991-05-10 |
1992-11-26 |
Celtrix Pharmaceuticals, Inc. |
Targeted delivery of bone growth factors
|
|
DE69112053D1
(de)
*
|
1991-07-22 |
1995-09-14 |
Bracco Int Bv |
Anwendung von Chelaten von Konjugaten mit paramagnetischen Metallen für Targetting.
|
|
US5521291A
(en)
*
|
1991-09-30 |
1996-05-28 |
Boehringer Ingelheim International, Gmbh |
Conjugates for introducing nucleic acid into higher eucaryotic cells
|
|
US5981273A
(en)
*
|
1991-09-30 |
1999-11-09 |
Boehringer Ingelheim Int'l. Gmbh |
Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
|
|
NZ244306A
(en)
*
|
1991-09-30 |
1995-07-26 |
Boehringer Ingelheim Int |
Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
|
|
US5922859A
(en)
*
|
1992-02-01 |
1999-07-13 |
Boehringer Ingelheim International Gmbh |
Complexes containing nucleic acid which can be taken-up by endocytosis into higher eukaryotic cells
|
|
EP0563475B1
(en)
*
|
1992-03-25 |
2000-05-31 |
Immunogen Inc |
Cell binding agent conjugates of derivatives of CC-1065
|
|
ATE190501T1
(de)
*
|
1992-05-28 |
2000-04-15 |
Univ Toledo |
Bereitstellung einer für krebszellen cytotoxischen verbindung unter verwendung des weges von plasminogenaktivatormaterial
|
|
US5679350A
(en)
*
|
1992-05-28 |
1997-10-21 |
The University Of Toledo |
Method of delivery of a medicament to a cancer cell using a pathway of plasminogen activator material
|
|
US5916772A
(en)
*
|
1992-06-16 |
1999-06-29 |
Whittier Institute For Diabetes And Endocrinology |
Recombinant production of saporin-containing proteins
|
|
US5393737A
(en)
*
|
1992-08-20 |
1995-02-28 |
Health Research, Inc. |
Cytotoxic drug conjugates for treatment of neoplastic diseases
|
|
ATE194658T1
(de)
*
|
1992-09-03 |
2000-07-15 |
Univ California |
Das dorsalgewebe beeinflussender faktor
|
|
US5466672A
(en)
*
|
1992-12-04 |
1995-11-14 |
Ophidian Pharmaceuticals, Inc. |
Therapeutic use of clostridium difficile toxin A
|
|
US6174530B1
(en)
|
1993-05-05 |
2001-01-16 |
Gryphon Sciences |
Homogeneous polyoxime compositions and their preparation by parallel assembly
|
|
CA2162157A1
(en)
|
1993-05-05 |
1994-11-10 |
Keith Rose |
Polyoxime compounds and their preparation
|
|
US6001364A
(en)
|
1993-05-05 |
1999-12-14 |
Gryphon Sciences |
Hetero-polyoxime compounds and their preparation by parallel assembly
|
|
US6214345B1
(en)
*
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
US5502037A
(en)
*
|
1993-07-09 |
1996-03-26 |
Neuromed Technologies, Inc. |
Pro-cytotoxic drug conjugates for anticancer therapy
|
|
US6491905B1
(en)
*
|
1993-09-14 |
2002-12-10 |
The Uab Research Foundation |
Recombinant bacterial cells for delivery of PNP to tumor cells
|
|
DE69425356T2
(de)
*
|
1993-09-22 |
2002-04-18 |
Hoechst Ag |
Pro-Prodrugs, ihre Herstellung und Anwendung
|
|
US5962220A
(en)
*
|
1993-10-26 |
1999-10-05 |
Thomas Jefferson University |
Compositions that specifically bind to colorectal cells and methods of using the same
|
|
US7097839B1
(en)
*
|
1993-10-26 |
2006-08-29 |
Thomas Jefferson University |
ST receptor binding compounds and methods of using the same
|
|
US5879656A
(en)
*
|
1993-10-26 |
1999-03-09 |
Thomas Jefferson University |
Methods of treating metastatic colorectal cancer with ST receptor binding compounds
|
|
DE69434279T2
(de)
*
|
1993-12-09 |
2006-04-06 |
Centro De Inmunologia Molecular |
Impfstoff, der einen menschlichen autologenen epidermalen Wachstumsfaktor enthält und dessen Verwendung
|
|
US6551618B2
(en)
*
|
1994-03-15 |
2003-04-22 |
University Of Birmingham |
Compositions and methods for delivery of agents for neuronal regeneration and survival
|
|
US5587459A
(en)
*
|
1994-08-19 |
1996-12-24 |
Regents Of The University Of Minnesota |
Immunoconjugates comprising tyrosine kinase inhibitors
|
|
US5911995A
(en)
*
|
1994-08-19 |
1999-06-15 |
Regents Of The University Of Minnesota |
EGF-genistein conjugates for the treatment of cancer
|
|
DE4433890C2
(de)
*
|
1994-09-22 |
1999-02-18 |
Deutsches Krebsforsch |
Konjugat aus einem Wirkstoff und einem nicht als körperfremd angesehenen, nativen Protein
|
|
PT788351E
(pt)
*
|
1994-11-10 |
2003-06-30 |
Univ Kentucky Res Foundation T |
Dispositivo implantavel recarregavel de libertacaocontrolada para administrar medicamentos direc tamente numa porcao interna do corpo
|
|
US5766899A
(en)
*
|
1995-02-27 |
1998-06-16 |
Board Of Regents , The University Of Texas System |
Targeted nucleic acid delivery into liver cells
|
|
US6015555A
(en)
*
|
1995-05-19 |
2000-01-18 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates
|
|
US20030119724A1
(en)
*
|
1995-11-22 |
2003-06-26 |
Ts`O Paul O.P. |
Ligands to enhance cellular uptake of biomolecules
|
|
EP0871490B1
(en)
*
|
1995-12-22 |
2003-03-19 |
Bristol-Myers Squibb Company |
Branched hydrazone linkers
|
|
US20050025740A1
(en)
*
|
1996-01-05 |
2005-02-03 |
Keith Rose |
Polyoxime compounds and their preparation
|
|
EA002400B1
(ru)
|
1996-03-12 |
2002-04-25 |
Пи Джи-Ти Экс Эл Компани, Л.П. |
Водорастворимые пролекарства противоракового действия
|
|
US6441025B2
(en)
*
|
1996-03-12 |
2002-08-27 |
Pg-Txl Company, L.P. |
Water soluble paclitaxel derivatives
|
|
US6030941A
(en)
*
|
1996-05-01 |
2000-02-29 |
Avi Biopharma, Inc. |
Polymer composition for delivering substances in living organisms
|
|
TW555765B
(en)
|
1996-07-09 |
2003-10-01 |
Amgen Inc |
Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
|
|
US5952294A
(en)
*
|
1996-07-31 |
1999-09-14 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Peptidyl prodrugs and methods of making and using the same
|
|
DE19636889A1
(de)
|
1996-09-11 |
1998-03-12 |
Felix Dr Kratz |
Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel
|
|
US6080383A
(en)
*
|
1997-01-13 |
2000-06-27 |
Rose; Samuel |
Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic agents into radioactive toxic precipitates in the cancer
|
|
US6767704B2
(en)
|
2000-03-27 |
2004-07-27 |
Thomas Jefferson University |
Methods of screening and diagnosing esophageal cancer by determining guanylin cyclase C expression
|
|
AU7124598A
(en)
*
|
1997-04-18 |
1998-11-13 |
Access Pharmaceuticals, Inc. |
Polymer-platinum compounds
|
|
US5965118A
(en)
*
|
1997-04-18 |
1999-10-12 |
Access Pharmaceuticals, Inc. |
Polymer-platinum compounds
|
|
US5998369A
(en)
*
|
1997-05-05 |
1999-12-07 |
Mayo Foundation For Medical Education And Research |
Treatment of osteoporosis
|
|
US6548482B1
(en)
|
1997-05-05 |
2003-04-15 |
Mayo Foundation For Medical Education And Research |
Treatment of osteoporosis
|
|
US6916790B2
(en)
|
1997-05-05 |
2005-07-12 |
Mayo Foundation For Medical Education And Research |
Treatment of osteoporosis
|
|
US6030997A
(en)
*
|
1998-01-21 |
2000-02-29 |
Eilat; Eran |
Acid labile prodrugs
|
|
US6866837B2
(en)
|
1998-06-05 |
2005-03-15 |
Mallinckrodt Inc. |
Radiolabeled peptides for the diagnosis and treatment of breast and prostate tumors and metastases of such tumors
|
|
CA2338000C
(en)
*
|
1998-07-17 |
2009-12-15 |
The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Water-soluble 4-thio-maleimido derivatives and methods for their production
|
|
US6747055B1
(en)
*
|
1998-07-17 |
2004-06-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Water-soluble drugs and methods for their production
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
GB9904582D0
(en)
*
|
1999-02-26 |
1999-04-21 |
Nycomed Imaging As |
Process
|
|
US7018654B2
(en)
*
|
1999-03-05 |
2006-03-28 |
New River Pharmaceuticals Inc. |
Pharmaceutical composition containing an active agent in an amino acid copolymer structure
|
|
US7060708B2
(en)
*
|
1999-03-10 |
2006-06-13 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
|
US6716452B1
(en)
*
|
2000-08-22 |
2004-04-06 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
|
US20010041189A1
(en)
*
|
1999-04-13 |
2001-11-15 |
Jingya Xu |
Poly(dipeptide) as a drug carrier
|
|
US6706892B1
(en)
*
|
1999-09-07 |
2004-03-16 |
Conjuchem, Inc. |
Pulmonary delivery for bioconjugation
|
|
US20030054977A1
(en)
*
|
1999-10-12 |
2003-03-20 |
Cell Therapeutics, Inc. |
Manufacture of polyglutamate-therapeutic agent conjugates
|
|
US7067111B1
(en)
*
|
1999-10-25 |
2006-06-27 |
Board Of Regents, University Of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
|
US20020077290A1
(en)
*
|
2000-03-17 |
2002-06-20 |
Rama Bhatt |
Polyglutamic acid-camptothecin conjugates and methods of preparation
|
|
IL153218A0
(en)
|
2000-06-02 |
2003-07-06 |
Univ Texas |
Ethylenedicysteine (ec) -drug conjugates
|
|
WO2002002147A2
(en)
*
|
2000-06-30 |
2002-01-10 |
Board Of Regents, The University Of Texas System |
Isolation of a cell-specific internalizing peptide that infiltrates tumor tissue for targeted drug delivery
|
|
US20020099013A1
(en)
*
|
2000-11-14 |
2002-07-25 |
Thomas Piccariello |
Active agent delivery systems and methods for protecting and administering active agents
|
|
US7163918B2
(en)
|
2000-08-22 |
2007-01-16 |
New River Pharmaceuticals Inc. |
Iodothyronine compositions
|
|
JP2004511510A
(ja)
*
|
2000-10-16 |
2004-04-15 |
ネオファーム、インコーポレイティッド |
ミトキサントロンのリポソーム製剤
|
|
US8394813B2
(en)
*
|
2000-11-14 |
2013-03-12 |
Shire Llc |
Active agent delivery systems and methods for protecting and administering active agents
|
|
WO2002043771A2
(en)
|
2000-12-01 |
2002-06-06 |
Cell Works Inc. |
Conjugates of glycosylated/galactosylated peptide
|
|
CU22999A1
(es)
|
2001-12-04 |
2004-10-12 |
Centro Inmunologia Molecular |
Método de tratamiento de enfermedades malignas e infecciosas crónicas
|
|
US20020197261A1
(en)
*
|
2001-04-26 |
2002-12-26 |
Chun Li |
Therapeutic agent/ligand conjugate compositions, their methods of synthesis and use
|
|
DK2163256T3
(en)
|
2001-05-11 |
2015-12-07 |
Ludwig Inst For Cancer Res Ltd |
Specific binding proteins and use thereof
|
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
|
EP1404334A4
(en)
*
|
2001-05-15 |
2005-02-02 |
Faulk Pharmaceuticals Inc |
TARGETED ADMINISTRATION OF BIOACTIVE COMPOUNDS FOR THE TREATMENT OF CANCER
|
|
PL367244A1
(en)
*
|
2001-05-15 |
2005-02-21 |
Faulk Pharmaceuticals, Inc. |
Targeted delivery of drugs for the treatment of viral infections
|
|
CA2451511A1
(en)
*
|
2001-06-22 |
2003-01-03 |
The University Of British Columbia |
Antimitotic eleuthesides
|
|
US20070066537A1
(en)
*
|
2002-02-22 |
2007-03-22 |
New River Pharmaceuticals Inc. |
Compounds and compositions for prevention of overdose of oxycodone
|
|
US7375083B2
(en)
*
|
2003-09-30 |
2008-05-20 |
Shire Llc |
Pharmaceutical compositions for prevention of overdose or abuse
|
|
US7169752B2
(en)
*
|
2003-09-30 |
2007-01-30 |
New River Pharmaceuticals Inc. |
Compounds and compositions for prevention of overdose of oxycodone
|
|
US7338939B2
(en)
*
|
2003-09-30 |
2008-03-04 |
New River Pharmaceuticals Inc. |
Abuse-resistant hydrocodone compounds
|
|
US20060014697A1
(en)
*
|
2001-08-22 |
2006-01-19 |
Travis Mickle |
Pharmaceutical compositions for prevention of overdose or abuse
|
|
US7375082B2
(en)
*
|
2002-02-22 |
2008-05-20 |
Shire Llc |
Abuse-resistant hydrocodone compounds
|
|
US20030109432A1
(en)
*
|
2001-12-10 |
2003-06-12 |
Zuo William W. |
Anticancer polypeptide-metal complexes and compositions, methods of making, and methods of using same
|
|
US7261875B2
(en)
*
|
2001-12-21 |
2007-08-28 |
Board Of Regents, The University Of Texas System |
Dendritic poly (amino acid) carriers and methods of use
|
|
RU2196604C1
(ru)
*
|
2001-12-21 |
2003-01-20 |
Северин Евгений Сергеевич |
Полипептид, являющийся аналогом рецепторсвязывающего фрагмента эпидермального фактора роста с 21-й по 31-ю аминокислоту, его конъюгат с доксорубицином и фармацевтическая композиция на его основе
|
|
CN1649614A
(zh)
|
2002-02-22 |
2005-08-03 |
新河药品股份有限公司 |
活性剂传递系统和保护及施用活性剂的方法
|
|
EP1531844B1
(en)
*
|
2002-02-22 |
2014-08-20 |
Shire LLC |
Novel sustained release pharmaceutical compounds to prevent abuse of controlled substances
|
|
US7659253B2
(en)
*
|
2002-02-22 |
2010-02-09 |
Shire Llc |
Abuse-resistant amphetamine prodrugs
|
|
KR20050010756A
(ko)
*
|
2002-02-22 |
2005-01-28 |
뉴 리버 파마슈티칼스, 인크. |
피험자 간 약물 혈청 농도의 변동성을 감소시키기 위한펩티드-약물 접합체의 용도
|
|
US7700561B2
(en)
*
|
2002-02-22 |
2010-04-20 |
Shire Llc |
Abuse-resistant amphetamine prodrugs
|
|
US7105486B2
(en)
*
|
2002-02-22 |
2006-09-12 |
New River Pharmaceuticals Inc. |
Abuse-resistant amphetamine compounds
|
|
EP2422772A3
(en)
|
2002-09-20 |
2012-04-18 |
Alpharma, Inc. |
Sequestering subunit and related compositions and methods
|
|
EP2316493A3
(en)
*
|
2002-11-07 |
2011-08-10 |
Board of Regents, The University of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
|
US7981667B2
(en)
*
|
2003-05-07 |
2011-07-19 |
Indiana University Research And Technology Corporation |
Alloyed semiconductor quantum dots and concentration-gradient alloyed quantum dots, series comprising the same and methods related thereto
|
|
CA2527646C
(en)
*
|
2003-05-29 |
2011-08-23 |
New River Pharmaceuticals Inc. |
Abuse resistant amphetamine compounds
|
|
WO2005016368A2
(en)
*
|
2003-08-19 |
2005-02-24 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Use of phosphophoryn for inducing biomineralization and bone regeneration
|
|
ATE516288T1
(de)
|
2003-10-22 |
2011-07-15 |
Us Gov Health & Human Serv |
Pyrrolobenzodiazepinderivate, zusammensetzungen, die diese enthalten, und damit in zusammenhang stehende verfahren
|
|
EP1694325A4
(en)
|
2003-12-03 |
2009-03-25 |
Univ New Jersey Med |
Method of preventing survival of retrovirally cells and of inhibiting formation of infectious retroviruses
|
|
ES2337904T3
(es)
*
|
2003-12-10 |
2010-04-30 |
Toudai Tlo, Ltd. |
Complejo de coordinacion de diaminociclohexano platino (ii) como copolimero de bloques que contiene un segmento poli(acido carboxilico) y agente antitumoral que lo comprende.
|
|
US9050378B2
(en)
*
|
2003-12-10 |
2015-06-09 |
Board Of Regents, The University Of Texas System |
N2S2 chelate-targeting ligand conjugates
|
|
HUE037549T2
(hu)
|
2004-04-07 |
2018-09-28 |
Rinat Neuroscience Corp |
Eljárások csontrákfájdalom kezelésére idegi növekedési faktor antagonista antitest beadásával
|
|
US8454927B2
(en)
*
|
2004-08-04 |
2013-06-04 |
Crystalplex Corporation |
Alloyed semiconductor nanocrystals
|
|
US20060036084A1
(en)
*
|
2004-08-04 |
2006-02-16 |
Lianhua Qu |
Conglomerated semiconductor nanocrystals
|
|
ES2555303T3
(es)
*
|
2005-06-09 |
2015-12-30 |
Nanocarrier Co., Ltd. |
Método para producir compuestos de coordinación polimerizados de un complejo de platino
|
|
RU2303997C2
(ru)
*
|
2005-09-27 |
2007-08-10 |
Автономная некоммерческая организация Научно-технический центр "Фармбиопресс" |
Конъюгат, обладающий избирательным действием по отношению к раковым опухолям
|
|
US7867977B2
(en)
*
|
2005-11-03 |
2011-01-11 |
The United States Of America As Represented By The Department Of Health And Human Services |
Immunogenic peptides and methods of use for treating and preventing cancer
|
|
RU2472812C2
(ru)
|
2005-12-05 |
2013-01-20 |
НИТТО ДЕНКО КОРПОРЭЙШН (Джэпэн/Джэпэн) |
Конъюгаты полиглутамат-аминокислота и способы
|
|
US7820174B2
(en)
|
2006-02-24 |
2010-10-26 |
The United States Of America As Represented By The Department Of Health And Human Services |
T cell receptors and related materials and methods of use
|
|
US9107863B2
(en)
*
|
2006-03-27 |
2015-08-18 |
The Buck Institute For Age Reasearch |
Reagents and methods for cancer treatment and prevention
|
|
US8758723B2
(en)
|
2006-04-19 |
2014-06-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for cellular imaging and therapy
|
|
RU2317102C1
(ru)
*
|
2006-05-31 |
2008-02-20 |
Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") |
Пептид, являющийся аналогом фрагмента альфа-фетопротеина, конъюгат пептида с доксорубицином и фармацевтическая композиция на его основе для лечения онкологических заболеваний
|
|
PL2484346T3
(pl)
|
2006-06-19 |
2017-07-31 |
Alpharma Pharmaceuticals Llc |
Kompozycje farmaceutyczne
|
|
US8088379B2
(en)
|
2006-09-26 |
2012-01-03 |
The United States Of America As Represented By The Department Of Health And Human Services |
Modified T cell receptors and related materials and methods
|
|
US10925977B2
(en)
*
|
2006-10-05 |
2021-02-23 |
Ceil>Point, LLC |
Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
|
|
SG175691A1
(en)
|
2006-10-31 |
2011-11-28 |
Us Gov Health & Human Serv |
Smoothened polypeptides and methods of use
|
|
AU2008206442B2
(en)
|
2007-01-12 |
2012-10-18 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
gp100-specific T cell receptors and related materials and methods of use
|
|
CA2676244C
(en)
*
|
2007-01-25 |
2017-01-17 |
Kwok-Kin Wong |
Use of anti-egfr antibodies in treatment of egfr mutant mediated disease
|
|
US20080181852A1
(en)
*
|
2007-01-29 |
2008-07-31 |
Nitto Denko Corporation |
Multi-functional Drug Carriers
|
|
MX2009009782A
(es)
|
2007-03-15 |
2010-09-10 |
Ludwig Inst Cancer Res |
Metodo de tratamiento que utiliza anticuerpos egfr e inhibidores de src y formulaciones relacionadas.
|
|
US20080253969A1
(en)
*
|
2007-04-10 |
2008-10-16 |
Nitto Denko Corporation |
Multi-functional polyglutamate drug carriers
|
|
JP2010526917A
(ja)
*
|
2007-05-09 |
2010-08-05 |
日東電工株式会社 |
複数種の薬物を有するポリグルタミン酸塩複合体及びポリグルタミン酸塩−アミノ酸複合体
|
|
DK2155255T3
(da)
|
2007-05-09 |
2013-09-02 |
Nitto Denko Corp |
Sammensætninger der omfatter en hydrofob forbindelse og et polyaminosyrekonjugat
|
|
DK2155254T3
(da)
*
|
2007-05-09 |
2013-03-04 |
Nitto Denko Corp |
Med platinlægemidler konjugerede polymere
|
|
EP2188311B1
(en)
|
2007-08-14 |
2016-10-05 |
Ludwig Institute for Cancer Research Ltd. |
Monoclonal antibody 175 targeting the egf receptor and derivatives and uses thereof
|
|
WO2009029844A1
(en)
*
|
2007-08-31 |
2009-03-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Compounds for inhibiting wip1, prodrugs and compositions thereof, and related methods
|
|
MX2010009670A
(es)
*
|
2008-03-06 |
2010-09-22 |
Nitto Denko Corp |
Conjugados de paclitaxel polimericos y metodos para tratamiento de cancer.
|
|
WO2010075303A1
(en)
|
2008-12-23 |
2010-07-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Splicing factors with a puf protein rna-binding domain and a splicing effector domain and uses of same
|
|
WO2010075417A1
(en)
|
2008-12-23 |
2010-07-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Survivin specific t cell receptor for treating cancer
|
|
WO2010088160A1
(en)
|
2009-01-28 |
2010-08-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors and related materials and methods of use
|
|
WO2010106544A1
(en)
*
|
2009-03-16 |
2010-09-23 |
Rajah Vijay Kumar |
A method and apparatus for - focused resonance nanopermeabilization (forn)
|
|
US8563513B2
(en)
|
2009-03-27 |
2013-10-22 |
Van Andel Research Institute |
Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
|
|
US9849146B2
(en)
|
2009-07-20 |
2017-12-26 |
Rutgers, The State University Of New Jersey |
Inhibition of nonsense mediated mRNA decay by drugs that prevent hypusination of eukaryotic initiation factor 5A
|
|
US8603814B2
(en)
*
|
2009-07-20 |
2013-12-10 |
Rutgers The State University Of New Jersey |
Method of inhibiting nonsense-mediated mRNA decay
|
|
WO2011032099A1
(en)
|
2009-09-11 |
2011-03-17 |
The Board Of Trustees Of The University Of Illinois |
Methods of treating diastolic dysfunction and related conditions
|
|
US20110076232A1
(en)
*
|
2009-09-29 |
2011-03-31 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
|
CA2776143A1
(en)
|
2009-10-01 |
2011-04-07 |
The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services |
Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer
|
|
WO2011044701A1
(en)
|
2009-10-16 |
2011-04-21 |
The University Of British Columbia |
Inhibitors of phosphatase and tensin homolog (pten) compositions, uses and methods
|
|
WO2011056572A1
(en)
|
2009-10-27 |
2011-05-12 |
The Board Of Trustees Of The University Of Illinois |
Methods of diagnosing diastolic dysfunction
|
|
CA2780572A1
(en)
|
2009-11-13 |
2011-05-19 |
The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services |
Modulated programmed death ligand-1
|
|
WO2011075393A2
(en)
|
2009-12-18 |
2011-06-23 |
Indiana University Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
|
BR112012018585A2
(pt)
|
2010-01-27 |
2017-01-10 |
Univ Indiana Res & Tech Corp |
conjungados e composições de glucagon antagonista-gip agonista para o tratamento de distúrbios metabólicos e de obesidade
|
|
DK2547359T3
(en)
|
2010-03-15 |
2016-06-06 |
The Board Of Trustees Of The Univ Of Illionis |
Inhibitors of beta integrin G-protein alpha subunit-BINDING INTERACTIONS
|
|
ES2876176T3
(es)
|
2010-09-21 |
2021-11-12 |
The Us Secretary Department Of Health And Human Services Office Of Technology Transfer National Inst |
Receptores de células T anti-SSX-2 y materiales relacionados y métodos de uso
|
|
WO2012054825A1
(en)
|
2010-10-22 |
2012-04-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mage-a3 t cell receptors and related materials and methods of use
|
|
EP2655401B1
(en)
|
2010-12-20 |
2016-03-09 |
The Regents of the University of Michigan |
Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
|
|
JP6086067B2
(ja)
|
2010-12-22 |
2017-03-01 |
インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション |
Gipレセプター活性を示すグルカゴンアナローグ
|
|
CN102675422B
(zh)
|
2011-03-15 |
2014-02-05 |
天津托普泰克生物科技有限公司 |
抗乙型肝炎病毒x蛋白多肽药物
|
|
PT3459560T
(pt)
|
2011-04-08 |
2021-05-24 |
Us Health |
Recetores de antigénio quimérico variante iii de recetor de fator de crescimento antiepidérmico e utilização dos mesmos para o tratamento de cancro
|
|
CN102746378B
(zh)
|
2011-04-22 |
2014-10-22 |
天津托普泰克生物科技有限公司 |
抗脂肪酸合成酶多肽及其应用
|
|
CN103748107B
(zh)
|
2011-06-09 |
2020-06-02 |
美利坚合众国, 由健康及人类服务部部长代表 |
具有免疫原性较小的t细胞和/或b细胞表位的假单胞菌外毒素a
|
|
EA031230B1
(ru)
|
2011-06-22 |
2018-12-28 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Агонисты глюкагонового рецептора/glp-1-рецептора
|
|
SI3392270T1
(sl)
|
2011-09-15 |
2020-12-31 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
T-celični receptorji, ki prepoznajo HLA-A1- ali HLA-CW7-omejeni MAGE
|
|
WO2013040141A1
(en)
|
2011-09-16 |
2013-03-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Pseudomonas exotoxin a with less immunogenic b cell epitopes
|
|
JP6267644B2
(ja)
|
2011-10-20 |
2018-01-24 |
アメリカ合衆国 |
抗cd22キメラ抗原受容体
|
|
RU2014117678A
(ru)
|
2011-11-17 |
2015-12-27 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Пептиды глюкагонового суперсемейства, обладающие глюкокортикоидной рецепторной активностью
|
|
CA3209571A1
(en)
|
2012-03-23 |
2013-09-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
|
SG11201406414WA
(en)
|
2012-04-11 |
2014-11-27 |
Us Health |
Chimeric antigen receptors targeting b-cell maturation antigen
|
|
JP6378172B2
(ja)
|
2012-05-22 |
2018-08-22 |
アメリカ合衆国 |
マウス抗ny−eso−1t細胞受容体
|
|
CN104619350A
(zh)
|
2012-06-14 |
2015-05-13 |
Ambrx公司 |
结合到核受体配体多肽的抗psma抗体
|
|
AR091478A1
(es)
|
2012-06-21 |
2015-02-04 |
Univ Indiana Res & Tech Corp |
Analogos de glucagon que exhiben actividad de receptor de gip (peptido insulinotropico dependiente de glucosa)
|
|
EP2864351B1
(en)
|
2012-06-21 |
2016-08-10 |
Indiana University Research and Technology Corporation |
Glucagon analogs exhibiting gip receptor activity
|
|
JP6461796B2
(ja)
|
2012-09-14 |
2019-01-30 |
アメリカ合衆国 |
Mhcクラスii拘束性mage−a3を認識するt細胞受容体
|
|
CN110229834B
(zh)
|
2012-10-24 |
2022-11-01 |
美国卫生和人力服务部 |
M971嵌合抗原受体
|
|
US20150320799A1
(en)
|
2012-12-20 |
2015-11-12 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
US9790282B2
(en)
|
2013-03-25 |
2017-10-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-CD276 polypeptides, proteins, and chimeric antigen receptors
|
|
WO2014205187A1
(en)
|
2013-06-20 |
2014-12-24 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Cytolethal distending toxin subunit b conjugated or fused to bacillus anthracis toxin lethal factor
|
|
CA2918216C
(en)
|
2013-07-15 |
2023-03-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-human papillomavirus 16 e6 t cell receptors
|
|
EP3038641B1
(en)
|
2013-10-06 |
2019-04-17 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Modified pseudomonas exotoxin a
|
|
CA2932424C
(en)
|
2013-12-06 |
2023-10-10 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Thymic stromal lymphopoietin receptor-specific chimeric antigen receptors and methods using same
|
|
MA51794A
(fr)
|
2014-04-23 |
2020-05-06 |
Juno Therapeutics Inc |
Procédés d'isolation, de culture et de modification génétique de populations de cellules immunitaires pour thérapie adoptive
|
|
CN106661098B
(zh)
|
2014-05-29 |
2021-05-04 |
美国卫生和人力服务部 |
抗人乳头瘤病毒16 e7的t细胞受体
|
|
JP6797693B2
(ja)
|
2014-06-02 |
2020-12-09 |
アメリカ合衆国 |
Cd−19を標的とするキメラ抗原受容体
|
|
MA40253A
(fr)
|
2014-07-15 |
2017-05-24 |
Juno Therapeutics Inc |
Cellules modifiées pour thérapie cellulaire adoptive
|
|
TWI751102B
(zh)
|
2014-08-28 |
2022-01-01 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
CN107106610A
(zh)
|
2014-10-20 |
2017-08-29 |
朱诺治疗学股份有限公司 |
用于过继细胞治疗中的给药的组合物和方法
|
|
WO2016071343A1
(en)
|
2014-11-03 |
2016-05-12 |
Immures S.R.L. |
T cell receptors
|
|
NZ769595A
(en)
|
2014-11-05 |
2023-06-30 |
Juno Therapeutics Inc |
Methods for transduction and cell processing
|
|
ES2987087T3
(es)
|
2014-12-03 |
2024-11-13 |
Juno Therapeutics Inc |
Métodos y composiciones para terapia celular adoptiva
|
|
AR103442A1
(es)
|
2015-01-16 |
2017-05-10 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antígenos quiméricos específicos de ror1
|
|
WO2016166568A1
(en)
|
2015-04-16 |
2016-10-20 |
Juno Therapeutics Gmbh |
Methods, kits and apparatus for expanding a population of cells
|
|
CN108174607A
(zh)
|
2015-05-29 |
2018-06-15 |
朱诺治疗学股份有限公司 |
用于遗传工程改造的细胞中调节抑制性相互作用的组合物和方法
|
|
MA42895A
(fr)
|
2015-07-15 |
2018-05-23 |
Juno Therapeutics Inc |
Cellules modifiées pour thérapie cellulaire adoptive
|
|
RU2021134624A
(ru)
|
2015-10-22 |
2022-03-15 |
Джуно Терапьютикс Гмбх |
Способы, наборы, средства и устройства для трансдукции
|
|
MA45488A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés, kits et appareil de culture de cellules
|
|
MA45489A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés de culture de cellules, kits et appareil associés
|
|
MA44314A
(fr)
|
2015-11-05 |
2018-09-12 |
Juno Therapeutics Inc |
Récepteurs chimériques contenant des domaines induisant traf, et compositions et méthodes associées
|
|
WO2017079703A1
(en)
|
2015-11-05 |
2017-05-11 |
Juno Therapeutics, Inc. |
Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy
|
|
EP3383892B1
(en)
|
2015-12-03 |
2022-12-21 |
Juno Therapeutics, Inc. |
Modified chimeric receptors and related compositions and methods
|
|
ES2901795T3
(es)
|
2015-12-04 |
2022-03-23 |
Juno Therapeutics Inc |
Métodos y composiciones relacionadas con la toxicidad asociada con la terapia celular
|
|
US20190287013A1
(en)
|
2016-03-16 |
2019-09-19 |
Juno Therapeutics, Inc. |
Methods for determining dosing of a therapeutic agent and related treatments
|
|
US20190355459A1
(en)
|
2016-03-16 |
2019-11-21 |
Juno Therapeutics, Inc. |
Methods for adaptive design of a treatment regimen and related treatments
|
|
KR20190021200A
(ko)
|
2016-03-22 |
2019-03-05 |
시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 |
독성을 예방 또는 경감시키기 위한 조기 개재 방법
|
|
EP3439675A4
(en)
|
2016-04-08 |
2019-12-18 |
Purdue Research Foundation |
METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
|
|
EP3452499A2
(en)
|
2016-05-06 |
2019-03-13 |
Juno Therapeutics, Inc. |
Genetically engineered cells and methods of making the same
|
|
CA3025516A1
(en)
|
2016-05-27 |
2017-11-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Flt3-specific chimeric antigen receptors and methods using same
|
|
MX2018014991A
(es)
|
2016-06-03 |
2019-08-29 |
Memorial Sloan Kettering Cancer Center |
Terapias adoptivas de celulas como opciones de tratamiento temprano.
|
|
MA45341A
(fr)
|
2016-06-06 |
2019-04-10 |
Hutchinson Fred Cancer Res |
Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive
|
|
CA3028002A1
(en)
|
2016-06-27 |
2018-01-04 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
MA45491A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
|
|
US20190201414A1
(en)
|
2016-07-01 |
2019-07-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv |
Inhibitor of heme degradation for use to improve antibiotic treatment of mycobacterium tuberculosis infection
|
|
MX2019001185A
(es)
|
2016-07-29 |
2019-10-21 |
Juno Therapeutics Inc |
Polipeptidos inmunomoduladores y composiciones y metodos relacionados.
|
|
MX2019003768A
(es)
|
2016-10-03 |
2019-06-24 |
Juno Therapeutics Inc |
Moleculas de enlace especificas de hpv.
|
|
CN110494565A
(zh)
|
2016-12-02 |
2019-11-22 |
朱诺治疗学股份有限公司 |
工程化b细胞及相关组合物和方法
|
|
US20190358262A1
(en)
|
2016-12-03 |
2019-11-28 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
|
AU2017368333A1
(en)
|
2016-12-03 |
2019-06-13 |
Juno Therapeutics, Inc. |
Methods for determining CAR-T cells dosing
|
|
MX2019006438A
(es)
|
2016-12-05 |
2019-11-28 |
Juno Therapeutics Inc |
Produccion de celulas modificadas para terapia de celulas adoptivas.
|
|
WO2018132518A1
(en)
|
2017-01-10 |
2018-07-19 |
Juno Therapeutics, Inc. |
Epigenetic analysis of cell therapy and related methods
|
|
WO2018134691A2
(en)
|
2017-01-20 |
2018-07-26 |
Juno Therapeutics Gmbh |
Cell surface conjugates and related cell compositions and methods
|
|
ES3010559T3
(en)
|
2017-02-28 |
2025-04-03 |
Endocyte Inc |
Compositions and methods for car t cell therapy
|
|
US20230190796A1
(en)
|
2017-04-07 |
2023-06-22 |
Juno Therapeutics, Inc. |
Engineered cells expressing prostate-specific membrane antigen (psma) or a modified form thereof and related methods
|
|
EP3615653B1
(en)
|
2017-04-27 |
2025-07-23 |
Juno Therapeutics, Inc. |
Oligomeric particle reagents and methods of use thereof
|
|
BR112019025403A2
(pt)
|
2017-06-02 |
2020-08-18 |
Juno Therapeutics Inc |
artigos de fabricação e métodos para tratamento usando terapia celular adotiva
|
|
MA48781A
(fr)
|
2017-06-02 |
2020-04-08 |
Juno Therapeutics Inc |
Articles de fabrication et procédés liés à la toxicité associée à la thérapie cellulaire
|
|
CN109517820B
(zh)
|
2017-09-20 |
2021-09-24 |
北京宇繁生物科技有限公司 |
一种靶向HPK1的gRNA以及HPK1基因编辑方法
|
|
MA50613A
(fr)
|
2017-10-03 |
2020-08-12 |
Editas Medicine Inc |
Molécules de liaison spécifique à l'hpv
|
|
WO2019089884A2
(en)
|
2017-11-01 |
2019-05-09 |
Editas Medicine, Inc. |
Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy
|
|
BR112020008638A2
(pt)
|
2017-11-01 |
2020-10-20 |
Juno Therapeutics Inc |
receptores de antígenos quiméricos específicos para antígenos de maturação de células b (bcma)
|
|
FI3704230T3
(fi)
|
2017-11-01 |
2024-12-27 |
Juno Therapeutics Inc |
Menetelmä muokattujen solujen terapeuttisten koostumusten muodostamiseksi
|
|
EP3703688A2
(en)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
|
JP7258899B2
(ja)
|
2017-11-01 |
2023-04-17 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞組成物を作製するための方法
|
|
EP3707258A1
(en)
|
2017-11-06 |
2020-09-16 |
Editas Medicine, Inc. |
Methods, compositions and components for crispr-cas9 editing of cblb in t cells for immunotherapy
|
|
EP3716980A1
(en)
|
2017-12-01 |
2020-10-07 |
Juno Therapeutics, Inc. |
Methods for dosing and for modulation of genetically engineered cells
|
|
JP2021505615A
(ja)
|
2017-12-08 |
2021-02-18 |
ジュノー セラピューティクス インコーポレイテッド |
細胞療法および関連方法のための表現型マーカー
|
|
KR102833956B1
(ko)
|
2017-12-08 |
2025-07-15 |
주노 쎄러퓨티크스 인코퍼레이티드 |
세포를 배양하기 위한 무혈청 배지 제형 및 이의 사용 방법
|
|
MX2020005908A
(es)
|
2017-12-08 |
2020-10-07 |
Juno Therapeutics Inc |
Proceso para producir una composicion de celulas t modificadas.
|
|
CN112204048A
(zh)
|
2017-12-15 |
2021-01-08 |
朱诺治疗学股份有限公司 |
抗cct5结合分子及其使用方法
|
|
WO2019144091A1
(en)
|
2018-01-22 |
2019-07-25 |
Endocyte, Inc. |
Methods of use for car t cells
|
|
EP3746117A1
(en)
|
2018-01-31 |
2020-12-09 |
Celgene Corporation |
Combination therapy using adoptive cell therapy and checkpoint inhibitor
|
|
CA3091674A1
(en)
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
EP3762012A1
(en)
|
2018-03-09 |
2021-01-13 |
Ospedale San Raffaele S.r.l. |
Il-1 antagonist and toxicity induced by cell therapy
|
|
JP7410868B2
(ja)
|
2018-04-05 |
2024-01-10 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞受容体およびそれを発現する操作された細胞
|
|
JP7589047B2
(ja)
|
2018-04-05 |
2024-11-25 |
ジュノー セラピューティクス インコーポレイテッド |
組換え受容体を発現する細胞の作製方法および関連組成物
|
|
BR112020020073A2
(pt)
|
2018-04-05 |
2021-01-05 |
Juno Therapeutics Inc |
Células t que expressam um receptor recombinante, polinucleotídeos relacionados e métodos
|
|
KR20210057730A
(ko)
|
2018-08-09 |
2021-05-21 |
주노 쎄러퓨티크스 인코퍼레이티드 |
조작 세포 및 이의 조성물 생성 방법
|
|
MX2021001519A
(es)
|
2018-08-09 |
2021-05-27 |
Juno Therapeutics Inc |
Metodos para valorar acidos nucleicos integrados.
|
|
CN112912105B
(zh)
|
2018-08-31 |
2024-07-16 |
因维克蒂斯股份有限公司 |
针对多种hla-g同种型的嵌合抗原受体
|
|
MX2021005013A
(es)
|
2018-10-31 |
2021-07-21 |
Juno Therapeutics Gmbh |
Métodos para la selección y estimulación de células y aparatos para los mismos.
|
|
BR112021007626A2
(pt)
|
2018-11-01 |
2021-10-13 |
Juno Therapeutics, Inc. |
Receptores antigênicos quiméricos específicos pa-ra receptor acoplado à proteína g receptor de classe c, grupo 5, membro d (gprc5d)
|
|
MX2021005024A
(es)
|
2018-11-01 |
2021-07-21 |
Juno Therapeutics Inc |
Metodos de tratamiento que utilizan receptores de antigenos quimericos especificos para antigeno de maduracion de celulas b.
|
|
JP7604366B2
(ja)
|
2018-11-06 |
2024-12-23 |
ジュノー セラピューティクス インコーポレイテッド |
遺伝子操作されたt細胞を作製するための方法
|
|
EP3880238A1
(en)
|
2018-11-16 |
2021-09-22 |
Juno Therapeutics, Inc. |
Methods of dosing engineered t cells for the treatment of b cell malignancies
|
|
PL3886894T3
(pl)
|
2018-11-30 |
2024-07-01 |
Juno Therapeutics, Inc. |
Metody dawkowania i leczenia nowotworów b-komórkowych w adoptywnej terapii komórkowej
|
|
CN113710256A
(zh)
|
2018-11-30 |
2021-11-26 |
朱诺治疗学股份有限公司 |
使用过继细胞疗法的治疗方法
|
|
BR112021014833A2
(pt)
|
2019-01-29 |
2021-10-05 |
Juno Therapeutics, Inc. |
Anticorpos e receptores antigênicos quiméricos específicos para receptor órfão 1 de tipo tirosina quinase de receptor (ror1)
|
|
US20220160771A1
(en)
|
2019-04-10 |
2022-05-26 |
Iulia Diaconu |
Flt3-specific chimeric antigen receptors and methods of using the same
|
|
CN113811329B
(zh)
|
2019-04-19 |
2025-10-14 |
天科雅生物科技有限公司 |
抗pd-1抗体和其用途
|
|
CA3136737A1
(en)
|
2019-05-01 |
2020-11-05 |
Juno Therapeutics, Inc. |
Cells expressing a recombinant receptor from a modified tgfbr2 locus, related polynucleotides and methods
|
|
CN114007640A
(zh)
|
2019-05-01 |
2022-02-01 |
朱诺治疗学股份有限公司 |
从修饰的cd247基因座表达嵌合受体的细胞、相关多核苷酸和方法
|
|
IL321262A
(en)
|
2019-05-22 |
2025-08-01 |
Massachusetts Inst Technology |
Circular RNA Preparations and Methods
|
|
CN112390894A
(zh)
|
2019-08-12 |
2021-02-23 |
广东东阳光药业有限公司 |
嵌合抗原受体及其应用
|
|
BR112022008023A2
(pt)
|
2019-10-30 |
2022-07-12 |
Juno Therapeutics Gmbh |
Dispositivos de seleção e/ou estimulação de células e métodos de uso
|
|
WO2021113770A1
(en)
|
2019-12-06 |
2021-06-10 |
Juno Therapeutics, Inc. |
Methods related to toxicity and response associated with cell therapy for treating b cell malignancies
|
|
KR20220146480A
(ko)
|
2020-01-28 |
2022-11-01 |
주노 쎄러퓨티크스 인코퍼레이티드 |
T 세포 형질도입 방법
|
|
US20230149462A1
(en)
|
2020-04-10 |
2023-05-18 |
Juno Therapeutics, Inc. |
Methods and uses related to cell therapy engineered with a chimeric antigen receptor targeting b-cell maturation antigen
|
|
EP4150640A1
(en)
|
2020-05-13 |
2023-03-22 |
Juno Therapeutics, Inc. |
Methods of identifying features associated with clinical response and uses thereof
|
|
CN116322788A
(zh)
|
2020-05-19 |
2023-06-23 |
奥纳治疗公司 |
环状rna组合物和方法
|
|
EP4171616A1
(en)
|
2020-06-26 |
2023-05-03 |
Juno Therapeutics GmbH |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
JP2023549780A
(ja)
|
2020-11-04 |
2023-11-29 |
ジュノー セラピューティクス インコーポレイテッド |
改変されたインバリアントcd3免疫グロブリンスーパーファミリー鎖遺伝子座からキメラ受容体を発現する細胞ならびに関連するポリヌクレオチドおよび方法
|
|
US20240168012A1
(en)
|
2021-03-22 |
2024-05-23 |
Juno Therapeutics, Inc. |
Methods of determining potency of a therapeutic cell composition
|
|
CN117916256A
(zh)
|
2021-05-06 |
2024-04-19 |
朱诺治疗学有限公司 |
用于刺激和转导t细胞的方法
|
|
CN115404240A
(zh)
|
2021-05-28 |
2022-11-29 |
上海环码生物医药有限公司 |
制备环形rna的构建体、方法及其用途
|
|
WO2023081735A1
(en)
|
2021-11-03 |
2023-05-11 |
Celgene Corporation |
Chimeric antigen receptors specific for b-cell maturation antigen for use in treating myeloma
|
|
WO2023081900A1
(en)
|
2021-11-08 |
2023-05-11 |
Juno Therapeutics, Inc. |
Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods
|
|
WO2023081526A1
(en)
|
2021-11-08 |
2023-05-11 |
Orna Therapeutics, Inc. |
Lipid nanoparticle compositions for delivering circular polynucleotides
|
|
US20250161359A1
(en)
|
2022-02-22 |
2025-05-22 |
Juno Therapeutics, Inc. |
Proteinase 3 (pr3) chimeric autoantibody receptor t cells and related methods and uses
|
|
US20250302954A1
(en)
|
2022-05-11 |
2025-10-02 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
|
US20250345432A1
(en)
|
2022-05-25 |
2025-11-13 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
|
JP2025523368A
(ja)
|
2022-05-30 |
2025-07-23 |
シャンハイ サーコード バイオメッド カンパニー,リミティド |
合成環状rna組成物及びその使用方法
|
|
KR20250029137A
(ko)
|
2022-06-22 |
2025-03-04 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Cd19-표적화된 car t 세포의 2차 요법을 위한 치료 방법
|
|
US12297285B2
(en)
|
2022-06-24 |
2025-05-13 |
Orna Therapeutics, Inc. |
Circular RNA encoding chimeric antigen receptors targeting BCMA
|
|
WO2024006960A1
(en)
|
2022-06-29 |
2024-01-04 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
|
JP2025525937A
(ja)
|
2022-08-05 |
2025-08-07 |
ジュノー セラピューティクス インコーポレイテッド |
Gprc5dおよびbcmaに特異的なキメラ抗原受容体
|
|
WO2024102730A1
(en)
|
2022-11-08 |
2024-05-16 |
Orna Therapeutics, Inc. |
Lipids and nanoparticle compositions for delivering polynucleotides
|
|
WO2024102762A1
(en)
|
2022-11-08 |
2024-05-16 |
Orna Therapeutics, Inc. |
Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
AR131320A1
(es)
|
2022-12-13 |
2025-03-05 |
Juno Therapeutics Inc |
Receptores de antígenos quiméricos específicos para baff-r y cd19 y métodos y usos de los mismos
|
|
EP4634390A2
(en)
|
2022-12-15 |
2025-10-22 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
WO2024205657A2
(en)
|
2023-03-29 |
2024-10-03 |
Orna Therapeutics, Inc. |
Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
AU2024269222A1
(en)
|
2023-05-05 |
2025-10-09 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
WO2025007148A1
(en)
|
2023-06-30 |
2025-01-02 |
Orna Therapeutics, Inc. |
Polymer lipid nanoparticle compositions for delivering circular polynucleotides
|
|
WO2025049690A1
(en)
|
2023-08-29 |
2025-03-06 |
Orna Therapeutics, Inc. |
Circular polyethylene glycol lipids
|
|
WO2025059362A1
(en)
|
2023-09-13 |
2025-03-20 |
Juno Therapeutics, Inc. |
Combination therapies with a cell therapy expressing a gprc5d-targeting car and related methods and uses
|
|
WO2025076472A1
(en)
|
2023-10-06 |
2025-04-10 |
Juno Therapeutics, Inc. |
Combination therapies with a cell therapy expressing a gprc5d-targeting car and related methods and uses
|
|
WO2025117969A1
(en)
|
2023-12-01 |
2025-06-05 |
Orna Therapeutics, Inc. |
Process for manufacturing lipid nanoparticles
|
|
WO2025147545A1
(en)
|
2024-01-03 |
2025-07-10 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids and related methods and uses
|