ATE190501T1 - Bereitstellung einer für krebszellen cytotoxischen verbindung unter verwendung des weges von plasminogenaktivatormaterial - Google Patents

Bereitstellung einer für krebszellen cytotoxischen verbindung unter verwendung des weges von plasminogenaktivatormaterial

Info

Publication number
ATE190501T1
ATE190501T1 AT93914191T AT93914191T ATE190501T1 AT E190501 T1 ATE190501 T1 AT E190501T1 AT 93914191 T AT93914191 T AT 93914191T AT 93914191 T AT93914191 T AT 93914191T AT E190501 T1 ATE190501 T1 AT E190501T1
Authority
AT
Austria
Prior art keywords
cancer cell
providing
compound
cytotoxic compound
activation material
Prior art date
Application number
AT93914191T
Other languages
English (en)
Inventor
Jerzy Jankun
Richard Hart
Original Assignee
Univ Toledo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toledo filed Critical Univ Toledo
Application granted granted Critical
Publication of ATE190501T1 publication Critical patent/ATE190501T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
AT93914191T 1992-05-28 1993-05-27 Bereitstellung einer für krebszellen cytotoxischen verbindung unter verwendung des weges von plasminogenaktivatormaterial ATE190501T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88978392A 1992-05-28 1992-05-28
US5981393A 1993-05-10 1993-05-10
PCT/US1993/005034 WO1993024141A1 (en) 1992-05-28 1993-05-27 Delivery of a cytotoxic compound to a cancer cell using a pathway of plasminogen activator material

Publications (1)

Publication Number Publication Date
ATE190501T1 true ATE190501T1 (de) 2000-04-15

Family

ID=26739215

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93914191T ATE190501T1 (de) 1992-05-28 1993-05-27 Bereitstellung einer für krebszellen cytotoxischen verbindung unter verwendung des weges von plasminogenaktivatormaterial

Country Status (6)

Country Link
EP (1) EP0643584B1 (de)
AT (1) ATE190501T1 (de)
AU (1) AU4394293A (de)
DE (1) DE69328092T2 (de)
ES (1) ES2143504T3 (de)
WO (1) WO1993024141A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001519647A (ja) * 1995-12-28 2001-10-23 カイロン コーポレイション 標的細胞中へのウイルスおよび粒子の取り込みおよびインターナリゼーションのためのレセプター特異的キメラウイルス表面ポリペプチド
US6277818B1 (en) 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
US5994309A (en) 1997-07-25 1999-11-30 Angstrom Pharmaceuticals, Inc. Anti-invasive and anti-angiogenic compositions and methods
AU2004290585A1 (en) * 2003-11-18 2005-06-02 Attenuon Llc Antibodies and/or conjugates thereof which bind to the amino terminal fragment of urokinase, compositions and uses thereof
WO2007044892A2 (en) * 2005-10-10 2007-04-19 American Diagnostica, Inc. Upar-binding molecule-drug conjugates and uses thereof
EP2117571B1 (de) 2006-12-08 2017-03-08 Monopar Therapeutics Inc. Plasminogen-aktivator-rezeptor-epitop vom urokinase-typ
US8877156B2 (en) 2007-06-26 2014-11-04 New York University Contrast agents anchored by thiols on nanoparticles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN165717B (de) * 1986-08-07 1989-12-23 Battelle Memorial Institute
WO1990012091A1 (en) * 1989-04-07 1990-10-18 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor

Also Published As

Publication number Publication date
ES2143504T3 (es) 2000-05-16
EP0643584A1 (de) 1995-03-22
EP0643584A4 (de) 1995-07-26
DE69328092T2 (de) 2000-07-20
WO1993024141A1 (en) 1993-12-09
EP0643584B1 (de) 2000-03-15
DE69328092D1 (de) 2000-04-20
AU4394293A (en) 1993-12-30

Similar Documents

Publication Publication Date Title
EP0504327A4 (en) Therapeutic uses of the hypervariable region of monoclonal antibody m195 and constructs thereof
IT1260656B (it) Articolo assorbente comprendente un materiale per il controllo dell'odore e relativo impiego.
HUT34348A (en) New process for producing immunotoxin conjugates
SE9504077D0 (sv) Vätskeabsorberande artikel ansedd för engångsanvändning
PH22075A (en) New complex compounds of piroxicam with cyclodextrin having antiinflammatory activity and pharmaceutical compositions containing them
GR1000529B (el) Ζελατινοειδες προιον χρησιμοποιουμενον δια ντους και αφριζον εκ των υστερων.
EP0670735A1 (de) Periphäralisierung hämatopoietischer stammzellen.
ATE190501T1 (de) Bereitstellung einer für krebszellen cytotoxischen verbindung unter verwendung des weges von plasminogenaktivatormaterial
DE69422034D1 (de) Isolierung, selektion und vermehrung von tierischen transgen-stammzellen
DE69414369D1 (de) Aerosol-spender und verfahren zu seiner herstellung
JPS5535019A (en) Carbostyryl derivative
ATE47711T1 (de) Biologisch aktive verbindung mit anti-prolyl endopeptidasewirkung.
ES449284A1 (es) Perfeccionamientos introducidos en un tubo de envase.
ATE160700T1 (de) Konjugate von biotin und deferoxamine für radio- immuntherapie und -immunbilderzeugung
DE3173520D1 (en) Shampoo composition
ES482808A1 (es) Un procedimiento para el mezclado continuo y uniforme de cantidades relativamente pequenas de aditivo liquido o li- cuado con cantidades relativamente grandes de material gra- nulado solido
ES8401335A1 (es) Procedimiento y dispositivo para encolar material particulado especialmente virutas lignocelulosicas.
ES2109182A1 (es) Formulacion liquida a base de cepas de los hongos filamentosos trichoderma harzianum y trichoderma viride.
UA29392C2 (uk) Пакувальний контейнер
AU3332389A (en) Monoclonal antibodies to tissue plasminogen activator (t-pa) which prolong its functional half-life
FR2506831A1 (fr) Procede de guidage d'une machine de forage en utilisant la radioactivite naturelle
MX9303136A (es) Metodo de entrega de un compuesto citotoxico a una celula cancerosa, que usa una trayectoria de material activo biologicamente.
ES2059836T3 (es) Granulados portadores que contienen substancias activas liquidas.
FR2703262B1 (fr) Mélanges gazeux.
TW336230B (en) Process for the production of olefinic unsaturated compounds

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee