FI823978A0 - Foerfarande foer framstaellning av 3-hydroxy-ml-236b-derivater - Google Patents
Foerfarande foer framstaellning av 3-hydroxy-ml-236b-derivaterInfo
- Publication number
- FI823978A0 FI823978A0 FI823978A FI823978A FI823978A0 FI 823978 A0 FI823978 A0 FI 823978A0 FI 823978 A FI823978 A FI 823978A FI 823978 A FI823978 A FI 823978A FI 823978 A0 FI823978 A0 FI 823978A0
- Authority
- FI
- Finland
- Prior art keywords
- derivater
- hydroxy
- foer faring
- faring framstaellning
- framstaellning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/365—Nocardia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56186641A JPS5889191A (ja) | 1981-11-20 | 1981-11-20 | 3−ヒドロキシ−ml−236b誘導体の製造法 |
JP18664181 | 1981-11-20 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI823978A0 true FI823978A0 (fi) | 1982-11-19 |
FI823978L FI823978L (fi) | 1983-05-21 |
FI70925B FI70925B (fi) | 1986-07-18 |
FI70925C FI70925C (fi) | 1986-10-27 |
Family
ID=16192138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI823978A FI70925C (fi) | 1981-11-20 | 1982-11-19 | Foerfarande foer framstaellning av 3-hydroxy-ml-236b-derivaterm-4 och m4' |
Country Status (18)
Country | Link |
---|---|
US (1) | US4537859A (fi) |
JP (1) | JPS5889191A (fi) |
KR (1) | KR880002483B1 (fi) |
AT (1) | AT387585B (fi) |
AU (1) | AU551720B2 (fi) |
BE (1) | BE895080A (fi) |
CA (1) | CA1186647A (fi) |
CH (1) | CH651065A5 (fi) |
DE (1) | DE3242849A1 (fi) |
DK (1) | DK159328C (fi) |
ES (1) | ES517542A0 (fi) |
FI (1) | FI70925C (fi) |
FR (1) | FR2516935A1 (fi) |
GB (1) | GB2111052B (fi) |
IT (1) | IT1191235B (fi) |
NL (1) | NL194373C (fi) |
SE (1) | SE453996B (fi) |
ZA (1) | ZA828535B (fi) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3682557D1 (de) * | 1985-09-13 | 1992-01-02 | Sankyo Co | Hydroxy-ml-236b-derivate, deren herstellung und anwendung. |
US5116870A (en) * | 1986-06-23 | 1992-05-26 | Merck & Co., Inc. | HMG-CoA reductase inhibitors |
USRE36481E (en) * | 1986-06-23 | 2000-01-04 | Merck & Co., Inc. | HMG-CoA reductase inhibitors |
US4940727A (en) * | 1986-06-23 | 1990-07-10 | Merck & Co., Inc. | Novel HMG-CoA reductase inhibitors |
US4833258A (en) * | 1987-02-17 | 1989-05-23 | Merck & Co., Inc. | Intermediates useful in the preparation of HMG-COA reductase inhibitors |
EP0306263B1 (en) * | 1987-09-02 | 1992-03-18 | Merck & Co. Inc. | Novel hmg-coa reductase inhibitors |
US4997848A (en) | 1987-10-27 | 1991-03-05 | Sankyo Company, Limited | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition |
EP0337548A3 (en) * | 1988-04-15 | 1991-08-14 | Merck & Co. Inc. | HMG-COA reductase inhibitors produced by nocardia SP. (MA6455)(ATCC 53695) |
US4997755A (en) * | 1988-04-15 | 1991-03-05 | Merck & Co., Inc. | HMG-CoA reductase inhibitors produced by Nocardia sp. (MA 6455) |
US4963538A (en) * | 1988-06-29 | 1990-10-16 | Merck & Co., Inc. | 5-oxygenated HMG-CoA reductase inhibitors |
US4970231A (en) * | 1989-06-09 | 1990-11-13 | Merck & Co., Inc. | 4-substituted HMG-CoA reductase inhibitors |
US5041562A (en) * | 1989-06-09 | 1991-08-20 | Merck & Co., Inc. | 3-keto HMG-CoA reductase inhibitors |
US4937259A (en) * | 1989-06-09 | 1990-06-26 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
US5010105A (en) * | 1989-06-09 | 1991-04-23 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
US5001241A (en) * | 1989-06-09 | 1991-03-19 | Merck & Co., Inc. | 3-KETO HMG-CoA reductase inhibitors |
US4997849A (en) * | 1989-06-23 | 1991-03-05 | Merck & Co., Inc. | Microbial transformation of simvastatin |
US4965200A (en) * | 1989-06-23 | 1990-10-23 | Merck & Co., Inc. | Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs |
US5112857A (en) * | 1990-09-04 | 1992-05-12 | Merck & Co., Inc. | Hmg-coa reductase inhibitor metabolites |
NZ250609A (en) * | 1992-12-28 | 1995-07-26 | Sankyo Co | Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments |
US6043064A (en) * | 1993-10-22 | 2000-03-28 | Bristol-Myers Squibb Company | Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof |
US5942423A (en) * | 1995-06-07 | 1999-08-24 | Massachusetts Institute Of Technology | Conversion of compactin to pravastatin by actinomadura |
SI9800144A (sl) | 1998-05-21 | 1999-12-31 | LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. | Nov biotehnološki postopek pridobivanja 3-hidroksi-ML-236B derivatov poznanih kot M-4 in M-4' |
SI20305A (sl) * | 1999-08-06 | 2001-02-28 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Kristali natrijeve soli pravastatina |
ATE360703T1 (de) | 1999-01-20 | 2007-05-15 | Kyowa Hakko Kogyo Kk | Verfahren zur herstellung von hemmern der hmg-coa reduktase |
AU2321600A (en) * | 1999-01-29 | 2000-08-18 | Kyowa Hakko Kogyo Co. Ltd. | Process for producing hmg-coa reductase inhibitor |
US6682913B1 (en) * | 1999-02-03 | 2004-01-27 | Institute For Drug Research Ltd. | Microbial process for preparing pravastatin |
HUP9902352A1 (hu) * | 1999-07-12 | 2000-09-28 | Gyógyszerkutató Intézet Kft. | Eljárás pravasztatin mikrobiológiai előállítására |
JP3737801B2 (ja) * | 2000-10-05 | 2006-01-25 | テバ ジョジセルジャール レースベニュタールシャシャーグ | プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウム、並びにそれを含む組成物 |
JP3236282B1 (ja) * | 2000-10-16 | 2001-12-10 | 三共株式会社 | プラバスタチンを精製する方法 |
JP2003093045A (ja) * | 2001-09-26 | 2003-04-02 | Godo Shusei Co Ltd | 有用変換微生物 |
AU2003226051A1 (en) * | 2002-04-16 | 2003-11-03 | Banyu Pharmaceutical Co., Ltd. | Solid forms of salts with tyrosine kinase activity |
US20040198800A1 (en) * | 2002-12-19 | 2004-10-07 | Geoffrey Allan | Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents |
JP2006513186A (ja) | 2002-12-20 | 2006-04-20 | ファイザー・プロダクツ・インク | Cetp阻害剤およびhmg−coaレダクターゼ阻害剤を含む剤形 |
US20040132771A1 (en) * | 2002-12-20 | 2004-07-08 | Pfizer Inc | Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors |
KR100470078B1 (ko) * | 2003-06-12 | 2005-02-04 | 씨제이 주식회사 | 컴팩틴을 프라바스타틴으로 전환할 수 있는 스트렙토마이세스 종(Streptomyces sp.)CJPV 975652 및 그를 이용한 프라바스타틴의 제조방법 |
CN1839114A (zh) | 2003-08-21 | 2006-09-27 | 默克弗罗斯特加拿大有限公司 | 组织蛋白酶半胱氨酸蛋白酶抑制剂 |
US20050101927A1 (en) * | 2003-09-11 | 2005-05-12 | Kimberly-Clark Worldwide, Inc. | Absorbent products comprising a moisturizing and lubricating composition |
WO2005051298A2 (en) | 2003-11-19 | 2005-06-09 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
TWI252253B (en) * | 2004-01-09 | 2006-04-01 | Chinese Petroleum Corp | A novel Pseudonocardia sp RMRC PAH4 and a process for bioconverting compactin into pravastatin using the same |
US20110217412A1 (en) * | 2004-07-30 | 2011-09-08 | Jinis Biopharmaceuticals Co. | Cholesterol lowering supplement and low cholesterol egg produced by using the same |
KR100637762B1 (ko) * | 2004-07-30 | 2006-10-23 | 주식회사 지니스 | 저콜레스테롤 란을 생산하기 위한 가금류용 사료첨가제 및 이를 이용한 저콜레스테롤 란의 생산방법 |
TWI307360B (en) | 2004-12-03 | 2009-03-11 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Process for constructing strain having compactin hydroxylation ability |
WO2006062876A2 (en) | 2004-12-09 | 2006-06-15 | Merck & Co., Inc. | Estrogen receptor modulators |
PT1855674E (pt) | 2005-03-02 | 2014-10-08 | Merck Canada Inc | Composição para a inibição de catepsina k |
ATE550019T1 (de) | 2005-05-17 | 2012-04-15 | Merck Sharp & Dohme | Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs |
PE20070335A1 (es) * | 2005-08-30 | 2007-04-21 | Novartis Ag | Benzimidazoles sustituidos y metodos para su preparacion |
GB0603041D0 (en) | 2006-02-15 | 2006-03-29 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
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US20110218176A1 (en) | 2006-11-01 | 2011-09-08 | Barbara Brooke Jennings-Spring | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
EP2109608B1 (en) | 2007-01-10 | 2011-03-23 | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. | Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors |
MX2009009304A (es) | 2007-03-01 | 2009-11-18 | Novartis Ag | Inhibidores de cinasa pim y metodos para su uso. |
CN101754965B (zh) | 2007-05-21 | 2014-03-19 | 诺华股份有限公司 | Csf-1r抑制剂、组合物及使用方法 |
US8389553B2 (en) | 2007-06-27 | 2013-03-05 | Merck Sharp & Dohme Corp. | 4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
CA2709677C (en) * | 2007-12-21 | 2017-03-14 | Lin Zhi | Selective androgen receptor modulators (sarms) and uses thereof |
JP5616328B2 (ja) * | 2008-04-25 | 2014-10-29 | 株式会社アモーレパシフィックAmorepacific Corporation | 生体内変換システムを利用したオルソ−ジヒドロキシイソフラボンの製造方法 |
US20120046364A1 (en) | 2009-02-10 | 2012-02-23 | Metabasis Therapeutics, Inc. | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use |
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WO2011163330A1 (en) | 2010-06-24 | 2011-12-29 | Merck Sharp & Dohme Corp. | Novel heterocyclic compounds as erk inhibitors |
CN103068980B (zh) | 2010-08-02 | 2017-04-05 | 瑟纳治疗公司 | 使用短干扰核酸(siNA)的RNA干扰介导的联蛋白(钙粘蛋白关联蛋白质),β1(CTNNB1)基因表达的抑制 |
KR102072631B1 (ko) | 2010-08-17 | 2020-02-03 | 시르나 쎄러퓨틱스 인코퍼레이티드 | 짧은 간섭 핵산 (siNA)을 사용한 B형 간염 바이러스 (HBV) 유전자 발현의 RNA 간섭 매개 억제 |
US8883801B2 (en) | 2010-08-23 | 2014-11-11 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors |
WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
US9242981B2 (en) | 2010-09-16 | 2016-01-26 | Merck Sharp & Dohme Corp. | Fused pyrazole derivatives as novel ERK inhibitors |
EP3766975A1 (en) | 2010-10-29 | 2021-01-20 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina) |
WO2012087772A1 (en) | 2010-12-21 | 2012-06-28 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
EP2675440B1 (en) | 2011-02-14 | 2020-03-25 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
US20140046059A1 (en) | 2011-04-21 | 2014-02-13 | Piramal Enterprises Limited | Process for the preparation of morpholino sulfonyl indole derivatives |
US9023865B2 (en) | 2011-10-27 | 2015-05-05 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
US20150299696A1 (en) | 2012-05-02 | 2015-10-22 | Sirna Therapeutics, Inc. | SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS |
WO2014052563A2 (en) | 2012-09-28 | 2014-04-03 | Merck Sharp & Dohme Corp. | Novel compounds that are erk inhibitors |
ES2651347T3 (es) | 2012-11-28 | 2018-01-25 | Merck Sharp & Dohme Corp. | Composiciones y métodos para el tratamiento del cáncer |
CA2895504A1 (en) | 2012-12-20 | 2014-06-26 | Merck Sharp & Dohme Corp. | Substituted imidazopyridines as hdm2 inhibitors |
US9540377B2 (en) | 2013-01-30 | 2017-01-10 | Merck Sharp & Dohme Corp. | 2,6,7,8 substituted purines as HDM2 inhibitors |
WO2015034925A1 (en) | 2013-09-03 | 2015-03-12 | Moderna Therapeutics, Inc. | Circular polynucleotides |
RU2692799C2 (ru) | 2013-10-08 | 2019-06-27 | Мерк Шарп И Доум Корп. | Ингибиторы цистеинпротеаз катепсинов |
WO2015051479A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
US10441567B2 (en) | 2014-01-17 | 2019-10-15 | Ligand Pharmaceuticals Incorporated | Methods and compositions for modulating hormone levels |
WO2015120580A1 (en) | 2014-02-11 | 2015-08-20 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
JO3589B1 (ar) | 2014-08-06 | 2020-07-05 | Novartis Ag | مثبطات كيناز البروتين c وطرق استخداماتها |
US10947234B2 (en) | 2017-11-08 | 2021-03-16 | Merck Sharp & Dohme Corp. | PRMT5 inhibitors |
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Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3392171A (en) * | 1964-03-20 | 1968-07-09 | Upjohn Co | 4-morpholino-4'-hydroxy bicyclohexyls |
US3281330A (en) * | 1964-03-20 | 1966-10-25 | Upjohn Co | Microbiological process for the oxygenation of cycloalkanes |
MX7065E (es) * | 1980-06-06 | 1987-04-10 | Sankyo Co | Un procedimiento microbiologico para preparar derivados de ml-236b |
-
1981
- 1981-11-20 JP JP56186641A patent/JPS5889191A/ja active Granted
-
1982
- 1982-11-16 CA CA000415650A patent/CA1186647A/en not_active Expired
- 1982-11-16 AU AU90610/82A patent/AU551720B2/en not_active Expired
- 1982-11-18 US US06/442,840 patent/US4537859A/en not_active Expired - Lifetime
- 1982-11-18 SE SE8206580A patent/SE453996B/sv not_active IP Right Cessation
- 1982-11-19 NL NL8204505A patent/NL194373C/nl not_active IP Right Cessation
- 1982-11-19 ES ES517542A patent/ES517542A0/es active Granted
- 1982-11-19 FR FR8219433A patent/FR2516935A1/fr active Granted
- 1982-11-19 ZA ZA828535A patent/ZA828535B/xx unknown
- 1982-11-19 BE BE0/209527A patent/BE895080A/fr unknown
- 1982-11-19 DK DK516182A patent/DK159328C/da not_active IP Right Cessation
- 1982-11-19 CH CH6754/82A patent/CH651065A5/de not_active IP Right Cessation
- 1982-11-19 DE DE19823242849 patent/DE3242849A1/de active Granted
- 1982-11-19 FI FI823978A patent/FI70925C/fi not_active IP Right Cessation
- 1982-11-20 KR KR8205250A patent/KR880002483B1/ko active
- 1982-11-22 IT IT68359/82A patent/IT1191235B/it active Protection Beyond IP Right Term
- 1982-11-22 GB GB08233267A patent/GB2111052B/en not_active Expired
- 1982-11-22 AT AT0425182A patent/AT387585B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE453996B (sv) | 1988-03-21 |
DK159328B (da) | 1990-10-01 |
CA1186647A (en) | 1985-05-07 |
ES8402350A1 (es) | 1984-01-16 |
NL194373B (nl) | 2001-10-01 |
FI823978L (fi) | 1983-05-21 |
DE3242849C2 (fi) | 1989-01-05 |
AU551720B2 (en) | 1986-05-08 |
FI70925C (fi) | 1986-10-27 |
GB2111052B (en) | 1985-05-09 |
KR840002451A (ko) | 1984-07-02 |
ES517542A0 (es) | 1984-01-16 |
BE895080A (fr) | 1983-03-16 |
JPS5889191A (ja) | 1983-05-27 |
IT1191235B (it) | 1988-02-24 |
FR2516935B1 (fi) | 1985-02-08 |
US4537859A (en) | 1985-08-27 |
KR880002483B1 (ko) | 1988-11-19 |
AU9061082A (en) | 1983-05-26 |
DE3242849A1 (de) | 1983-06-01 |
DK159328C (da) | 1991-02-25 |
DK516182A (da) | 1983-05-21 |
NL8204505A (nl) | 1983-06-16 |
GB2111052A (en) | 1983-06-29 |
IT8268359A0 (it) | 1982-11-22 |
AT387585B (de) | 1989-02-10 |
CH651065A5 (de) | 1985-08-30 |
SE8206580L (sv) | 1983-05-21 |
ZA828535B (en) | 1983-10-26 |
FR2516935A1 (fr) | 1983-05-27 |
JPH0371116B2 (fi) | 1991-11-12 |
SE8206580D0 (sv) | 1982-11-18 |
FI70925B (fi) | 1986-07-18 |
ATA425182A (de) | 1988-07-15 |
NL194373C (nl) | 2002-02-04 |
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MA | Patent expired |
Owner name: SANKYO COMPANY LIMITED |