FI81104C - Foerfarande foer framstaellning av antibiotiskt aktivt kristallint 7-/d- -amino- - (3-klor-4-hydroxifenyl)acetamido/-3-metyl-3-cefem-4-karboxylsyramonohydrat. - Google Patents

Foerfarande foer framstaellning av antibiotiskt aktivt kristallint 7-/d- -amino- - (3-klor-4-hydroxifenyl)acetamido/-3-metyl-3-cefem-4-karboxylsyramonohydrat. Download PDF

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Publication number
FI81104C
FI81104C FI844756A FI844756A FI81104C FI 81104 C FI81104 C FI 81104C FI 844756 A FI844756 A FI 844756A FI 844756 A FI844756 A FI 844756A FI 81104 C FI81104 C FI 81104C
Authority
FI
Finland
Prior art keywords
acid
acetonitrile
amino
chloro
monohydrate
Prior art date
Application number
FI844756A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI844756A0 (fi
FI844756L (fi
FI81104B (fi
Inventor
Daniel Bouzard
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of FI844756A0 publication Critical patent/FI844756A0/fi
Publication of FI844756L publication Critical patent/FI844756L/fi
Application granted granted Critical
Publication of FI81104B publication Critical patent/FI81104B/fi
Publication of FI81104C publication Critical patent/FI81104C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI844756A 1983-12-06 1984-12-03 Foerfarande foer framstaellning av antibiotiskt aktivt kristallint 7-/d- -amino- - (3-klor-4-hydroxifenyl)acetamido/-3-metyl-3-cefem-4-karboxylsyramonohydrat. FI81104C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8319463 1983-12-06
FR8319463A FR2555989B1 (fr) 1983-12-06 1983-12-06 Monohydrate de chlorocephadroxyle

Publications (4)

Publication Number Publication Date
FI844756A0 FI844756A0 (fi) 1984-12-03
FI844756L FI844756L (fi) 1985-06-07
FI81104B FI81104B (fi) 1990-05-31
FI81104C true FI81104C (fi) 1990-09-10

Family

ID=9294877

Family Applications (1)

Application Number Title Priority Date Filing Date
FI844756A FI81104C (fi) 1983-12-06 1984-12-03 Foerfarande foer framstaellning av antibiotiskt aktivt kristallint 7-/d- -amino- - (3-klor-4-hydroxifenyl)acetamido/-3-metyl-3-cefem-4-karboxylsyramonohydrat.

Country Status (25)

Country Link
JP (1) JPH0794461B2 (it)
KR (1) KR920001769B1 (it)
AT (1) AT386411B (it)
AU (1) AU567780B2 (it)
BE (1) BE901218A (it)
CA (1) CA1246545A (it)
CH (1) CH662569A5 (it)
CY (1) CY1559A (it)
DE (1) DE3444367A1 (it)
DK (1) DK579984A (it)
ES (1) ES8605279A1 (it)
FI (1) FI81104C (it)
FR (1) FR2555989B1 (it)
GB (1) GB2150931B (it)
GR (1) GR81159B (it)
HK (1) HK72590A (it)
IE (1) IE57832B1 (it)
IT (1) IT1177370B (it)
LU (1) LU85670A1 (it)
MY (1) MY102192A (it)
NL (1) NL8403670A (it)
SE (1) SE8406171L (it)
SG (1) SG48890G (it)
YU (1) YU45221B (it)
ZA (1) ZA849415B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505697A1 (fr) * 1981-05-12 1982-11-19 Humblot Bernard Unite perfectionnee de soudage electrique

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US516047A (en) * 1894-03-06 Wire bed-bottom
US3489750A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
US3781282A (en) * 1971-01-20 1973-12-25 W Garbrecht Cephalosporin process and product
YU39709B (en) * 1972-09-15 1985-04-30 Bristol Myers Co Process for producing cephalosporin
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
DE2317179C2 (de) * 1973-04-05 1982-11-25 Bristol-Myers Co., 10154 New York, N.Y. Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
JPS5356311A (en) * 1976-10-28 1978-05-22 Toyama Chem Co Ltd Cefalexin monohydrate having novel crystal form and process for preparationof the same
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
US4600773A (en) * 1983-12-01 1986-07-15 Eli Lilly And Company Crystalline cephalexin hydrochloride monohydrate

Also Published As

Publication number Publication date
YU207384A (en) 1987-12-31
GB2150931A (en) 1985-07-10
CA1246545A (en) 1988-12-13
YU45221B (en) 1992-05-28
DK579984A (da) 1985-06-07
ES538235A0 (es) 1986-03-16
GB2150931B (en) 1987-07-29
DE3444367A1 (de) 1985-06-20
IE57832B1 (en) 1993-04-21
CY1559A (en) 1991-03-22
GR81159B (en) 1985-04-08
IT8423909A1 (it) 1986-06-05
JPH0794461B2 (ja) 1995-10-11
FR2555989A1 (fr) 1985-06-07
ATA386384A (de) 1988-01-15
SE8406171L (sv) 1985-06-07
FI844756A0 (fi) 1984-12-03
FR2555989B1 (fr) 1987-02-20
AU567780B2 (en) 1987-12-03
JPS60139695A (ja) 1985-07-24
FI844756L (fi) 1985-06-07
DE3444367C2 (it) 1993-04-29
ES8605279A1 (es) 1986-03-16
FI81104B (fi) 1990-05-31
AT386411B (de) 1988-08-25
LU85670A1 (fr) 1985-09-12
AU3632184A (en) 1985-06-13
SG48890G (en) 1990-08-17
BE901218A (fr) 1985-06-05
CH662569A5 (fr) 1987-10-15
SE8406171D0 (sv) 1984-12-05
NL8403670A (nl) 1985-07-01
IE843117L (en) 1985-06-06
IT8423909A0 (it) 1984-12-05
IT1177370B (it) 1987-08-26
KR850004494A (ko) 1985-07-15
HK72590A (en) 1990-09-21
DK579984D0 (da) 1984-12-05
KR920001769B1 (ko) 1992-03-02
ZA849415B (en) 1985-07-31
MY102192A (en) 1992-04-30
GB8430753D0 (en) 1985-01-16

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MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS SQUIBB COMPANY