FI70900C - Foerfarande foer framstaellning av terapeutiskt anvaendbara imdazotia- och imidazooxadiazolalkenkarboxylsyraamider - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara imdazotia- och imidazooxadiazolalkenkarboxylsyraamider Download PDF

Info

Publication number
FI70900C
FI70900C FI811630A FI811630A FI70900C FI 70900 C FI70900 C FI 70900C FI 811630 A FI811630 A FI 811630A FI 811630 A FI811630 A FI 811630A FI 70900 C FI70900 C FI 70900C
Authority
FI
Finland
Prior art keywords
alkyl
general formula
methyl
phenyl
hydroxyalkyl
Prior art date
Application number
FI811630A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI70900B (fi
FI811630L (fi
Inventor
Horst Meyer
Harald Horstmann
Eike Moeller
Bernward Garthoff
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19803020421 external-priority patent/DE3020421A1/de
Priority claimed from DE19803043158 external-priority patent/DE3043158A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI811630L publication Critical patent/FI811630L/fi
Priority to FI831950A priority Critical patent/FI71745C/fi
Publication of FI70900B publication Critical patent/FI70900B/fi
Application granted granted Critical
Publication of FI70900C publication Critical patent/FI70900C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI811630A 1980-05-29 1981-05-27 Foerfarande foer framstaellning av terapeutiskt anvaendbara imdazotia- och imidazooxadiazolalkenkarboxylsyraamider FI70900C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI831950A FI71745C (fi) 1980-05-29 1983-05-31 Foerfarande foer framstaellning av -(imidazo-/2,1-b/-1,3,4-tiadiazol-5-yl)-alkenkarboxylsyror, vilka aer mellanprodukter vid framstaellning av diuretiska imidazotiadiazolalken- karboxylsyraaminer.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19803020421 DE3020421A1 (de) 1980-05-29 1980-05-29 Imidazoazolalkensaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln
DE3020421 1980-05-29
DE19803043158 DE3043158A1 (de) 1980-11-15 1980-11-15 Imidazoazolalkensaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln
DE3043158 1980-11-15

Publications (3)

Publication Number Publication Date
FI811630L FI811630L (fi) 1981-11-30
FI70900B FI70900B (fi) 1986-07-18
FI70900C true FI70900C (fi) 1986-10-27

Family

ID=25785736

Family Applications (1)

Application Number Title Priority Date Filing Date
FI811630A FI70900C (fi) 1980-05-29 1981-05-27 Foerfarande foer framstaellning av terapeutiskt anvaendbara imdazotia- och imidazooxadiazolalkenkarboxylsyraamider

Country Status (13)

Country Link
US (1) US4444770A (hu)
EP (1) EP0041215B1 (hu)
AU (1) AU543307B2 (hu)
CA (1) CA1188690A (hu)
DE (1) DE3173607D1 (hu)
DK (1) DK233281A (hu)
ES (1) ES502573A0 (hu)
FI (1) FI70900C (hu)
GR (1) GR74557B (hu)
HU (1) HU186887B (hu)
IL (1) IL62960A (hu)
NO (2) NO811630L (hu)
PT (1) PT73058B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208437A1 (de) * 1982-03-09 1983-09-15 Bayer Ag, 5090 Leverkusen Imidazothiadiazolalkencarbonsaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln
DE3329621A1 (de) * 1983-08-17 1985-02-28 Bayer Ag, 5090 Leverkusen Aminoalkyl-imidazothiadiazol-alkencarbonsaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln
IT1213175B (it) * 1984-06-06 1989-12-14 Mediolanum Farmaceutici Srl Derivati imidazotiazolmetilen-acetidrazidi, loro preparazione e composizioni farmaceutiche ad attivita'diuretica.
DE3542661A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung
DE3542662A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Imidazothiadiazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung und ihre verwendung zur behandlung von krankheiten
TW438796B (en) * 1996-05-15 2001-06-07 Hoffmann La Roche 2,4-diaminopyrimidine derivatives, the manufacture process thereof, and the antibiotically-active pharmaceutical composition containing the same
CA2527903A1 (en) * 2003-06-13 2004-12-23 Aegera Therapeutics, Inc. Imidazo[2,1-b]-1,3,4-thiadiazole sulfoxides and sulfones
DE102005010215A1 (de) * 2005-03-05 2006-09-07 Bayer Cropscience Ag Heterobicyclische Acrylamide
DK2193133T3 (en) 2007-09-27 2015-10-05 Fundacion Ct Nac Investigaciones Oncologicas Carlos Iii IMIDAZOLOTHIADIAZOLES USED AS PROTEINKINASE INHIBITORS
US8318928B2 (en) * 2008-12-15 2012-11-27 Glenmark Pharmaceuticals, S.A. Fused imidazole carboxamides as TRPV3 modulators
JP5615902B2 (ja) 2009-04-02 2014-10-29 セントロ ナシオナル デ インベスティガシオネス オンコロヒカス（セエネイオ）Ｃｅｎｔｒｏ Ｎａｃｉｏｎａｌ Ｄｅ Ｉｎｖｅｓｔｉｇａｃｉｏｎｅｓ Ｏｎｃｏｌｏｇｉｃａｓ（Ｃｎｉｏ） イミダゾ［２，１−ｂ］［１，３，４］チアジアゾール誘導体
WO2011045646A1 (en) * 2009-10-13 2011-04-21 Council Of Scientific & Industrial Research Imidazothiazole-chalcone derivatives as potential anticancer agents and process for the preparation thereof
MX2012005678A (es) 2009-11-16 2012-09-07 Univ California Enhibidores de cinasas.
CN104540835B (zh) 2012-04-26 2017-08-08 百时美施贵宝公司 用于治疗血小板聚集的作为蛋白酶激活受体4(par4)抑制剂的咪唑并噻二唑衍生物
HUE060743T2 (hu) 2012-04-26 2023-04-28 Bristol Myers Squibb Co Gyógyszerészeti kompozíciók, amelyek tartalmaznak imidazothiadiazol- és imidazopiridazinszármazékokat mint proteáz aktívált receptor 4 (PAR4) inhibitorokat trombocitaaggregációk kezelésére
JP6101343B2 (ja) 2012-04-26 2017-03-22 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 血小板凝集を治療するためのプロテアーゼ活性化受容体４（ｐａｒ４）阻害剤としてのイミダゾチアジアゾールおよびイミダゾピリダジン誘導体
AR108906A1 (es) 2016-06-29 2018-10-10 Bristol Myers Squibb Co Heterociclos de biarilmetilo
BR112022007404A2 (pt) 2019-10-21 2022-07-05 Novartis Ag Compostos e composições para o tratamento de doenças parasíticas

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615639A (en) * 1967-10-23 1971-10-26 Eastman Kodak Co Direct positive silver halide emulsions containing dyes as electron acceptors and spectral sensitizers
US3804823A (en) * 1972-02-15 1974-04-16 Eastman Kodak Co Heterocyclic containing monoazo compounds
US4042583A (en) * 1973-09-20 1977-08-16 Pfizer Inc. Imidazo[2,1-b]thiazole and thiazolo[3,2-a]-benzimidazole quaternary salts as hypoglycemic agents and growth promotants
DE2361451C2 (de) * 1973-12-10 1982-06-03 Bayer Ag, 5090 Leverkusen Triazolothiazolyl-(thiono)-phosphor (phosphon)-säureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung zur Bekämpfung von Insekten, Milben und Zecken
AT340414B (de) * 1975-02-18 1977-12-12 Plantex Ltd Verfahren zur herstellung von neuen imidazo(2,1-b)thiazolderivaten und ihren salzen
US4263311A (en) * 1976-09-27 1981-04-21 Smithkline Corporation 5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles
DE2823686A1 (de) * 1978-05-31 1979-12-06 Bayer Ag Imidazo eckige klammer auf 2.1-b eckige klammer zu eckige klammer auf 1.3.4 eckige klammer zu -thiadiazole
DE2902763A1 (de) * 1979-01-25 1980-08-07 Basf Ag Basische farbstoffe

Also Published As

Publication number Publication date
IL62960A (en) 1986-04-29
DE3173607D1 (en) 1986-03-13
AU543307B2 (en) 1985-04-18
ES8203897A1 (es) 1982-04-01
FI70900B (fi) 1986-07-18
EP0041215B1 (de) 1986-01-29
DK233281A (da) 1981-11-30
GR74557B (hu) 1984-06-29
NO811630L (no) 1981-11-30
AU7090081A (en) 1981-12-03
IL62960A0 (en) 1981-07-31
NO854688L (no) 1981-11-30
ES502573A0 (es) 1982-04-01
US4444770A (en) 1984-04-24
EP0041215A3 (en) 1982-04-14
FI811630L (fi) 1981-11-30
PT73058A (en) 1981-06-01
CA1188690A (en) 1985-06-11
HU186887B (en) 1985-10-28
EP0041215A2 (de) 1981-12-09
PT73058B (en) 1982-07-01

Similar Documents

Publication Publication Date Title
FI70900C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara imdazotia- och imidazooxadiazolalkenkarboxylsyraamider
EP0404525B1 (en) Sulfur-containing fused pyrimidine derivatives, their production and use
US3711489A (en) Certain 8,9-dihydro(3,4,7,8)cycloocta(1,2-d)imidazoles
BG60936B2 (bg) Нови производни на бициклични аминокиселини,методи за тяхното получаване,средства,които ги съдържат и тяхното приложение,както и нови бициклични аминокиселини като междинни продукти и методи за тяхно то получаване
KR20200087786A (ko) 타피나로프의 제조 방법
JP2024525976A (ja) ベンゾ［ｂ］セレノフェン系ＳＴＩＮＧ調節剤、その製造方法及び使用
PT89089B (pt) Processo de preparacao de derivados de alquilaminas substituidas e de composicoes farmaceuticas que os contem
EP1098891B1 (de) Polycyclische thiazolidin-2-yliden amine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
Herz et al. Sulfur analogs of isoquinolines. IV. The Pictet-Gams reaction and attempts to prepare analogs of papaverine1, 2
EP0078241A2 (de) Furane
PT749970E (pt) Aminometilcromanos benzoisotiazolil-substituidos
GB1586655A (en) Pyrido-indole transquilising agents
US3306909A (en) 3-carbamoyl-1,5-diphenyl-2,4-pyrrolidinediones
Sato et al. Studies on Uricosuric Diuretics. I.: Syntheses and Activities of Xanthonyloxyacetic Acids and Dihydrofuroxanthone-2-carboxylic Acids
JPS634544B2 (hu)
Artico et al. Non‐Steroidal antiinflammatory agents. 1. A novel synthesis of 1‐methyl‐5‐p‐tolylpyrrole‐2‐acetic acid (tolmetin)
DK172306B1 (da) Naphthoxazinderivater, fremstilling af disse og naphthoxazinderivaterne til anvendelse som lægemidler, samt farmaceutiske præparater
GB2025397A (en) Arylacetic acid derivatives
KR20050091086A (ko) 인데논카르복실산 유도체 및 당뇨병 및 이상지혈증의 치료및 예방을 위한 이의 용도
US3442890A (en) Substituted 3-benzazocin-16-ones
EP0197533B1 (en) Dioxolobenzisoxazole derivatives and process for preparing the same
US4663319A (en) 3-(1,3-dithiol-2-ylidene)-2,4-dioxopyrrolidines, -piperidines, and -hexahydroazepines and use thereof against hepatic diseases
EP0041630A1 (en) New 3H-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing them
NO171499B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5,6-dihydro-4h-cyklo-penta(b)tiofen-6-karboksylsyre-derivater
HU190969B (en) Process for preparing aminoalkyl-imidazo-thidaiazolyl-alkane-carboxylic acid amides and pharmaceutical compositions thereof as active substances

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BAYER AKTIENGESELLSCHAFT