FI69842C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav - Google Patents
Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav Download PDFInfo
- Publication number
- FI69842C FI69842C FI801929A FI801929A FI69842C FI 69842 C FI69842 C FI 69842C FI 801929 A FI801929 A FI 801929A FI 801929 A FI801929 A FI 801929A FI 69842 C FI69842 C FI 69842C
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- Prior art keywords
- amino
- pyridyl
- formula
- triazole
- mono
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- -1 4-PYRIDYL Chemical class 0.000 title claims description 63
- 238000000034 method Methods 0.000 title claims description 39
- 238000002360 preparation method Methods 0.000 title claims description 26
- 230000001225 therapeutic effect Effects 0.000 title description 3
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- 150000001875 compounds Chemical class 0.000 claims description 21
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- PHYOJNNPPUPKEA-UHFFFAOYSA-N 5-pyridin-4-yl-1h-1,2,4-triazol-3-amine Chemical compound NC1=NNC(C=2C=CN=CC=2)=N1 PHYOJNNPPUPKEA-UHFFFAOYSA-N 0.000 claims description 14
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- 238000009835 boiling Methods 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000007810 chemical reaction solvent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000002026 chloroform extract Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000013058 crude material Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 description 1
- 238000004455 differential thermal analysis Methods 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- LIWAQLJGPBVORC-UHFFFAOYSA-N ethylmethylamine Chemical compound CCNC LIWAQLJGPBVORC-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 150000002366 halogen compounds Chemical class 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 239000008241 heterogeneous mixture Substances 0.000 description 1
- 239000003485 histamine H2 receptor antagonist Substances 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 description 1
- 229910000039 hydrogen halide Inorganic materials 0.000 description 1
- 239000012433 hydrogen halide Substances 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical class I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- ZTUJDPKOHPKRMO-UHFFFAOYSA-N hydron;2,2,2-trifluoroethanamine;chloride Chemical compound Cl.NCC(F)(F)F ZTUJDPKOHPKRMO-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000000401 methanolic extract Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- GRZMHVMPNBYGJN-UHFFFAOYSA-N n-(diaminomethylideneamino)-2-(ethylamino)pyridine-4-carboxamide Chemical compound CCNC1=CC(C(=O)NNC(N)=N)=CC=N1 GRZMHVMPNBYGJN-UHFFFAOYSA-N 0.000 description 1
- LLCQVHDYDSFORX-UHFFFAOYSA-N n-[2-(3-chlorophenyl)ethyl]-4-[3-(methylamino)-1h-1,2,4-triazol-5-yl]pyridin-2-amine Chemical compound CNC1=NNC(C=2C=C(NCCC=3C=C(Cl)C=CC=3)N=CC=2)=N1 LLCQVHDYDSFORX-UHFFFAOYSA-N 0.000 description 1
- QKIQMAGIAXWWGZ-UHFFFAOYSA-N n-benzyl-4-[3-(dimethylamino)-1h-1,2,4-triazol-5-yl]-n-methylpyridin-2-amine Chemical compound CN(C)C1=NNC(C=2C=C(N=CC=2)N(C)CC=2C=CC=CC=2)=N1 QKIQMAGIAXWWGZ-UHFFFAOYSA-N 0.000 description 1
- PAKITBQKLHWLMJ-UHFFFAOYSA-N n-benzyl-4-[3-(ethylamino)-1h-1,2,4-triazol-5-yl]pyridin-2-amine Chemical compound CCNC1=NNC(C=2C=C(NCC=3C=CC=CC=3)N=CC=2)=N1 PAKITBQKLHWLMJ-UHFFFAOYSA-N 0.000 description 1
- RGHMUCAEUWODRH-UHFFFAOYSA-N n-dodecyl-n-ethyl-4-[3-(methylamino)-1h-1,2,4-triazol-5-yl]pyridin-2-amine Chemical compound C1=NC(N(CC)CCCCCCCCCCCC)=CC(C=2NN=C(NC)N=2)=C1 RGHMUCAEUWODRH-UHFFFAOYSA-N 0.000 description 1
- IWNIPFZRVVHSPJ-UHFFFAOYSA-N n-ethyl-4-(1h-1,2,4-triazol-5-yl)pyridin-2-amine Chemical compound C1=NC(NCC)=CC(C2=NNC=N2)=C1 IWNIPFZRVVHSPJ-UHFFFAOYSA-N 0.000 description 1
- BBZFBSDOIWITNB-UHFFFAOYSA-N n-ethyl-4-[3-(methylamino)-1h-1,2,4-triazol-5-yl]pyridin-2-amine Chemical class C1=NC(NCC)=CC(C=2NN=C(NC)N=2)=C1 BBZFBSDOIWITNB-UHFFFAOYSA-N 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000012746 preparative thin layer chromatography Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000006798 ring closing metathesis reaction Methods 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000012258 stirred mixture Substances 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229940055764 triaz Drugs 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/86—Hydrazides; Thio or imino analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4973779 | 1979-06-18 | ||
| US06/049,737 US4276297A (en) | 1979-06-18 | 1979-06-18 | Pyridylaminotriazole therapeutic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI801929A7 FI801929A7 (fi) | 1980-12-19 |
| FI69842B FI69842B (fi) | 1985-12-31 |
| FI69842C true FI69842C (fi) | 1986-05-26 |
Family
ID=21961428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI801929A FI69842C (fi) | 1979-06-18 | 1980-06-16 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4276297A (it) |
| JP (1) | JPS565477A (it) |
| KR (2) | KR840002173B1 (it) |
| AR (2) | AR225766A1 (it) |
| AT (2) | AT375655B (it) |
| BE (1) | BE883859A (it) |
| CA (1) | CA1140133A (it) |
| CH (1) | CH644375A5 (it) |
| DE (1) | DE3022302C2 (it) |
| DK (1) | DK258180A (it) |
| ES (2) | ES492522A0 (it) |
| FI (1) | FI69842C (it) |
| FR (1) | FR2459241A1 (it) |
| GB (1) | GB2053910B (it) |
| GR (1) | GR68731B (it) |
| IE (1) | IE49913B1 (it) |
| IL (1) | IL60332A (it) |
| IT (1) | IT1140993B (it) |
| LU (1) | LU82527A1 (it) |
| NL (1) | NL182641C (it) |
| PH (1) | PH16875A (it) |
| PT (1) | PT71399A (it) |
| SE (1) | SE441745B (it) |
| YU (2) | YU41717B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR230994A1 (es) * | 1981-08-31 | 1984-08-31 | Pfizer | Procedimiento para preparar compuesto de 3'-substituido-5'-(2-amino-4-piridil)-1',2',4'-triazol |
| JP2518515Y2 (ja) * | 1993-09-22 | 1996-11-27 | 茂郎 槇島 | 水虫用医療包帯 |
| PL415073A1 (pl) * | 2014-12-19 | 2016-06-20 | Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością | Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1925654U (de) | 1965-07-23 | 1965-10-21 | Alfons Mann | Zusatzeinrichtung fuer vergaser an benzinmotoren zur steigerung der motorenleistung. |
| CH521419A (de) * | 1968-03-01 | 1972-04-15 | Ciba Geigy Ag | Verfahren zur Herstellung neuer Azofarbstoffe |
| GB1264798A (it) | 1968-07-10 | 1972-02-23 | ||
| US3647814A (en) * | 1969-07-03 | 1972-03-07 | Rohm & Haas | Method for preparing 4-substituted-1 2 4-triazoles |
| NL7112373A (it) * | 1970-09-25 | 1972-03-28 | ||
| NL7112372A (it) * | 1970-09-25 | 1972-03-28 | ||
| GB1403866A (en) * | 1971-12-06 | 1975-08-28 | Wyeth John & Brother Ltd | Derivatives of 3-amino-1,2,4-triazoles |
| US3879404A (en) * | 1972-07-07 | 1975-04-22 | John J Baldwin | Certain 5-(pyridyl)-3(phenyl)-1,2,4-triazoles |
| US3873563A (en) * | 1972-09-29 | 1975-03-25 | Sakai Chemical Industry Co | Method for manufacturing 4-amino-1,2,4-triazoles |
| US3928361A (en) * | 1973-05-21 | 1975-12-23 | Merck & Co Inc | 1-(Sulfamoylphenylalkyl)-3,5-dipyridyl-1,2,4 triazoles |
| US3984558A (en) * | 1973-05-21 | 1976-10-05 | Merck & Co., Inc. | 1,3,5-Trisubstituted-1,2,4-triazole compounds used as bronchodilators |
-
1979
- 1979-06-18 US US06/049,737 patent/US4276297A/en not_active Expired - Lifetime
-
1980
- 1980-06-06 CH CH440280A patent/CH644375A5/fr not_active IP Right Cessation
- 1980-06-06 AR AR281310A patent/AR225766A1/es active
- 1980-06-12 GR GR62187A patent/GR68731B/el unknown
- 1980-06-13 DE DE3022302A patent/DE3022302C2/de not_active Expired
- 1980-06-16 CA CA000354112A patent/CA1140133A/en not_active Expired
- 1980-06-16 PT PT71399A patent/PT71399A/pt unknown
- 1980-06-16 PH PH24137A patent/PH16875A/en unknown
- 1980-06-16 LU LU82527A patent/LU82527A1/fr unknown
- 1980-06-16 FI FI801929A patent/FI69842C/fi not_active IP Right Cessation
- 1980-06-16 YU YU1587/80A patent/YU41717B/xx unknown
- 1980-06-16 JP JP8126680A patent/JPS565477A/ja active Granted
- 1980-06-17 FR FR8013401A patent/FR2459241A1/fr active Granted
- 1980-06-17 IL IL60332A patent/IL60332A/xx unknown
- 1980-06-17 IT IT22825/80A patent/IT1140993B/it active
- 1980-06-17 NL NLAANVRAGE8003496,A patent/NL182641C/xx not_active IP Right Cessation
- 1980-06-17 DK DK258180A patent/DK258180A/da not_active Application Discontinuation
- 1980-06-17 SE SE8004498A patent/SE441745B/sv not_active IP Right Cessation
- 1980-06-17 IE IE1250/80A patent/IE49913B1/en unknown
- 1980-06-17 GB GB8019674A patent/GB2053910B/en not_active Expired
- 1980-06-17 AT AT0319280A patent/AT375655B/de not_active IP Right Cessation
- 1980-06-17 KR KR1019800002385A patent/KR840002173B1/ko not_active Expired
- 1980-06-17 ES ES492522A patent/ES492522A0/es active Granted
- 1980-06-17 BE BE0/201060A patent/BE883859A/fr not_active IP Right Cessation
-
1981
- 1981-01-26 ES ES498821A patent/ES8201155A1/es not_active Expired
- 1981-08-04 AR AR286650A patent/AR227436A1/es active
-
1982
- 1982-11-24 YU YU2633/82A patent/YU41536B/xx unknown
-
1983
- 1983-08-29 AT AT0307583A patent/AT375656B/de not_active IP Right Cessation
-
1984
- 1984-04-30 KR KR1019840002324A patent/KR840002172B1/ko not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: PFIZER INC. |