FI69842C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav Download PDF

Info

Publication number
FI69842C
FI69842C FI801929A FI801929A FI69842C FI 69842 C FI69842 C FI 69842C FI 801929 A FI801929 A FI 801929A FI 801929 A FI801929 A FI 801929A FI 69842 C FI69842 C FI 69842C
Authority
FI
Finland
Prior art keywords
amino
pyridyl
formula
triazole
mono
Prior art date
Application number
FI801929A
Other languages
English (en)
Finnish (fi)
Other versions
FI801929A (fi
FI69842B (fi
Inventor
Christopher Andrew Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI801929A publication Critical patent/FI801929A/fi
Publication of FI69842B publication Critical patent/FI69842B/fi
Application granted granted Critical
Publication of FI69842C publication Critical patent/FI69842C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86—Hydrazides; Thio or imino analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI801929A 1979-06-18 1980-06-16 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav FI69842C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4973779 1979-06-18
US06/049,737 US4276297A (en) 1979-06-18 1979-06-18 Pyridylaminotriazole therapeutic agents

Publications (3)

Publication Number Publication Date
FI801929A FI801929A (fi) 1980-12-19
FI69842B FI69842B (fi) 1985-12-31
FI69842C true FI69842C (fi) 1986-05-26

Family

ID=21961428

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801929A FI69842C (fi) 1979-06-18 1980-06-16 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav

Country Status (24)

Country Link
US (1) US4276297A (it)
JP (1) JPS565477A (it)
KR (2) KR840002173B1 (it)
AR (2) AR225766A1 (it)
AT (2) AT375655B (it)
BE (1) BE883859A (it)
CA (1) CA1140133A (it)
CH (1) CH644375A5 (it)
DE (1) DE3022302C2 (it)
DK (1) DK258180A (it)
ES (2) ES492522A0 (it)
FI (1) FI69842C (it)
FR (1) FR2459241A1 (it)
GB (1) GB2053910B (it)
GR (1) GR68731B (it)
IE (1) IE49913B1 (it)
IL (1) IL60332A (it)
IT (1) IT1140993B (it)
LU (1) LU82527A1 (it)
NL (1) NL182641C (it)
PH (1) PH16875A (it)
PT (1) PT71399A (it)
SE (1) SE441745B (it)
YU (2) YU41717B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR230994A1 (es) * 1981-08-31 1984-08-31 Pfizer Procedimiento para preparar compuesto de 3'-substituido-5'-(2-amino-4-piridil)-1',2',4'-triazol
JP2518515Y2 (ja) * 1993-09-22 1996-11-27 茂郎 槇島 水虫用医療包帯
PL415073A1 (pl) * 2014-12-19 2016-06-20 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1925654U (de) 1965-07-23 1965-10-21 Alfons Mann Zusatzeinrichtung fuer vergaser an benzinmotoren zur steigerung der motorenleistung.
CH521419A (de) * 1968-03-01 1972-04-15 Ciba Geigy Ag Verfahren zur Herstellung neuer Azofarbstoffe
GB1264798A (it) 1968-07-10 1972-02-23
US3647814A (en) * 1969-07-03 1972-03-07 Rohm & Haas Method for preparing 4-substituted-1 2 4-triazoles
NL7112373A (it) * 1970-09-25 1972-03-28
NL7112372A (it) * 1970-09-25 1972-03-28
GB1403866A (en) * 1971-12-06 1975-08-28 Wyeth John & Brother Ltd Derivatives of 3-amino-1,2,4-triazoles
US3879404A (en) * 1972-07-07 1975-04-22 John J Baldwin Certain 5-(pyridyl)-3(phenyl)-1,2,4-triazoles
US3873563A (en) * 1972-09-29 1975-03-25 Sakai Chemical Industry Co Method for manufacturing 4-amino-1,2,4-triazoles
US3984558A (en) * 1973-05-21 1976-10-05 Merck & Co., Inc. 1,3,5-Trisubstituted-1,2,4-triazole compounds used as bronchodilators
US3928361A (en) * 1973-05-21 1975-12-23 Merck & Co Inc 1-(Sulfamoylphenylalkyl)-3,5-dipyridyl-1,2,4 triazoles

Also Published As

Publication number Publication date
IE49913B1 (en) 1986-01-08
GB2053910A (en) 1981-02-11
DE3022302A1 (de) 1981-01-08
SE441745B (sv) 1985-11-04
JPS617426B2 (it) 1986-03-06
NL182641C (nl) 1988-04-18
PH16875A (en) 1984-04-02
GR68731B (it) 1982-02-10
KR840004687A (ko) 1984-10-22
SE8004498L (sv) 1980-12-19
GB2053910B (en) 1983-04-20
PT71399A (en) 1980-07-01
AR225766A1 (es) 1982-04-30
ES498821A0 (es) 1981-12-01
FI801929A (fi) 1980-12-19
FR2459241B1 (it) 1983-06-17
ATA319280A (de) 1984-01-15
CH644375A5 (fr) 1984-07-31
IT1140993B (it) 1986-10-10
YU158780A (en) 1983-04-30
ES8105313A1 (es) 1981-06-01
FR2459241A1 (fr) 1981-01-09
LU82527A1 (fr) 1981-02-03
AR227436A1 (es) 1982-10-29
DE3022302C2 (de) 1984-03-01
ES8201155A1 (es) 1981-12-01
IT8022825A0 (it) 1980-06-17
IL60332A (en) 1983-09-30
FI69842B (fi) 1985-12-31
IE801250L (en) 1980-12-18
KR840002173B1 (ko) 1984-11-26
KR840002172B1 (ko) 1984-11-26
ES492522A0 (es) 1981-06-01
IL60332A0 (en) 1980-09-16
KR830002756A (ko) 1983-05-30
AT375655B (de) 1984-08-27
NL8003496A (nl) 1980-12-22
BE883859A (fr) 1980-12-17
AT375656B (de) 1984-08-27
ATA307583A (de) 1984-01-15
CA1140133A (en) 1983-01-25
US4276297A (en) 1981-06-30
YU41536B (en) 1987-08-31
DK258180A (da) 1980-12-19
YU41717B (en) 1987-12-31
YU263382A (en) 1983-04-30
JPS565477A (en) 1981-01-20
NL182641B (nl) 1987-11-16

Similar Documents

Publication Publication Date Title
DE69221059T2 (de) Indolderivate und antiulcerose Zubereitungen
US7381732B2 (en) Pyrazolobenzamides and derivatives as factor Xa inhibitors
US4616025A (en) Thiazolidine derivatives, process for the preparation and pharmaceutical compositions thereof
WO2006041831A2 (en) Cyclic β-amino acid derivatives as factor xa inhibitors
US4020072A (en) 5-Aminomethyl-1H-pyrazolo[3,4-b]pyridines
CS248750B2 (en) Production method of the 2-(n-subst.guanidino)-4-heteroarylthiazols
FI72974C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara imidazolylpyridiner.
FI78481B (fi) Ett nytt foerfarande foer framstaellning av 2-guanidino-4-(2-substituerad-amino-4-imidazolyl)tiazoler och detta foerfarandes nya mellanprodukter.
FI69842C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-amino-5-(4-pyridyl)-1,2,4-triazolbaser och farmaceutisktgodtagbara syraadditionssalter daerav
SK197A3 (en) Imidazopyridine-azolidinones, preparation method thereof, pharmaceutical composition containing same and their use
EP0074229B1 (en) Triazole gastric anti-secretory agents
US4465683A (en) Anti-psychotic agents
NO770014L (no) Fremgangsm}te til fremstilling av hydroazinderivater.
SU1217258A3 (ru) Способ получени производных 2-гуанидино-4-гетероарилтиазола или их фармацевтически приемлемых кислотно-аддитивных солей
JPH06135925A (ja) ヒスタミンｈ▲２▼−受容体拮抗活性をもつ置換３，４−ジアミノ−１，２，５−チアジアゾール用中間体
JPS62212386A (ja) ２−ピリジルメチルベンズイミダゾ−ル誘導体
JPS63230670A (ja) 置換ピリジル酢酸誘導体
FI73990C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva imidazolylpyridiner.
Smith et al. Amidrazones. 8. Synthesis of 1, 2, 4‐oxdiazoles by thermolysis of N3‐acylamidrazone ylides
JPH0688974B2 (ja) ２−ピリジルアセタミド誘導体、その製法および用途
CS244699B2 (cs) Způsob výroby v poloze 9 substituovaných derivátů 4-oxo-4H- -pyrido[1,2-a]-pyrimidinu
PL137068B1 (en) Method of obtaining novel /2-/(aminopyridinylo/amino/phenyl arylmetanones

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: PFIZER INC.