ES8105313A1 - Un procedimiento para la preparacion de bases de 3-amino-5-(4-piridil) 1,2,4-triazol. - Google Patents

Un procedimiento para la preparacion de bases de 3-amino-5-(4-piridil) 1,2,4-triazol.

Info

Publication number
ES8105313A1
ES8105313A1 ES492522A ES492522A ES8105313A1 ES 8105313 A1 ES8105313 A1 ES 8105313A1 ES 492522 A ES492522 A ES 492522A ES 492522 A ES492522 A ES 492522A ES 8105313 A1 ES8105313 A1 ES 8105313A1
Authority
ES
Spain
Prior art keywords
pyridyl
amino
triazole
pyridylaminotriazole
therapeutic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492522A
Other languages
English (en)
Other versions
ES492522A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES492522A0 publication Critical patent/ES492522A0/es
Publication of ES8105313A1 publication Critical patent/ES8105313A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86—Hydrazides; Thio or imino analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE BASES DE 3-AMINO-5-(4-PIRIDIL)-1,2,4-TRIAZOL. CONSTA DE LAS SIGUIENTES ETAPAS: 1. SOMETER A CICLACION UN COMPUESTO DE FORMULA GENERAL (I), EN QUE Y ES CLORO O BROMO; Y ELEVADO A 1 ES HIDROGENO, ALQUILO INFERIOR, CLORO O BROMO, 2. REACCION DEL PRODUCTO OBTENIDO CON UNA BASE AMINICA. SE OBTIENE EL COMPUESTO DE FORMULA GENERAL II. AMBAS ETAPAS SON SIMULTANEAS. SE EMPLEAN COMO MINIMO 3 MOLES DE BASE AMINICA POR CADA MOL DE COMPUESTO DE PARTIDAS HALOGENADO. LA REACCION ES UN DISOLVENTE INERTE TAL COMO AGUA A UNA TEMPERATURA COMPRENDIDA ENTRE 80 Y 250GC. *FORMULA*
ES492522A 1979-06-18 1980-06-17 Un procedimiento para la preparacion de bases de 3-amino-5-(4-piridil) 1,2,4-triazol. Expired ES8105313A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/049,737 US4276297A (en) 1979-06-18 1979-06-18 Pyridylaminotriazole therapeutic agents

Publications (2)

Publication Number Publication Date
ES492522A0 ES492522A0 (es) 1981-06-01
ES8105313A1 true ES8105313A1 (es) 1981-06-01

Family

ID=21961428

Family Applications (2)

Application Number Title Priority Date Filing Date
ES492522A Expired ES8105313A1 (es) 1979-06-18 1980-06-17 Un procedimiento para la preparacion de bases de 3-amino-5-(4-piridil) 1,2,4-triazol.
ES498821A Expired ES8201155A1 (es) 1979-06-18 1981-01-26 Un procedimiento para la preparacion de bases de 3-ami- no-5-(4-piridil)-1,2,4-triazol

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES498821A Expired ES8201155A1 (es) 1979-06-18 1981-01-26 Un procedimiento para la preparacion de bases de 3-ami- no-5-(4-piridil)-1,2,4-triazol

Country Status (24)

Country Link
US (1) US4276297A (es)
JP (1) JPS565477A (es)
KR (2) KR840002173B1 (es)
AR (2) AR225766A1 (es)
AT (2) AT375655B (es)
BE (1) BE883859A (es)
CA (1) CA1140133A (es)
CH (1) CH644375A5 (es)
DE (1) DE3022302C2 (es)
DK (1) DK258180A (es)
ES (2) ES8105313A1 (es)
FI (1) FI69842C (es)
FR (1) FR2459241A1 (es)
GB (1) GB2053910B (es)
GR (1) GR68731B (es)
IE (1) IE49913B1 (es)
IL (1) IL60332A (es)
IT (1) IT1140993B (es)
LU (1) LU82527A1 (es)
NL (1) NL182641C (es)
PH (1) PH16875A (es)
PT (1) PT71399A (es)
SE (1) SE441745B (es)
YU (2) YU41717B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR230994A1 (es) * 1981-08-31 1984-08-31 Pfizer Procedimiento para preparar compuesto de 3'-substituido-5'-(2-amino-4-piridil)-1',2',4'-triazol
JP2518515Y2 (ja) * 1993-09-22 1996-11-27 茂郎 槇島 水虫用医療包帯
US9440953B2 (en) * 2014-12-19 2016-09-13 OncoArendi Therapeutics Sp. z o.o. Substituted amino triazoles useful as acidic mammalian chitinase inhibitors
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1925654U (de) 1965-07-23 1965-10-21 Alfons Mann Zusatzeinrichtung fuer vergaser an benzinmotoren zur steigerung der motorenleistung.
CH521419A (de) * 1968-03-01 1972-04-15 Ciba Geigy Ag Verfahren zur Herstellung neuer Azofarbstoffe
GB1264798A (es) 1968-07-10 1972-02-23
US3647814A (en) * 1969-07-03 1972-03-07 Rohm & Haas Method for preparing 4-substituted-1 2 4-triazoles
NL7112373A (es) * 1970-09-25 1972-03-28
NL7112372A (es) * 1970-09-25 1972-03-28
GB1403866A (en) * 1971-12-06 1975-08-28 Wyeth John & Brother Ltd Derivatives of 3-amino-1,2,4-triazoles
US3879404A (en) * 1972-07-07 1975-04-22 John J Baldwin Certain 5-(pyridyl)-3(phenyl)-1,2,4-triazoles
US3873563A (en) * 1972-09-29 1975-03-25 Sakai Chemical Industry Co Method for manufacturing 4-amino-1,2,4-triazoles
US3984558A (en) * 1973-05-21 1976-10-05 Merck & Co., Inc. 1,3,5-Trisubstituted-1,2,4-triazole compounds used as bronchodilators
US3928361A (en) * 1973-05-21 1975-12-23 Merck & Co Inc 1-(Sulfamoylphenylalkyl)-3,5-dipyridyl-1,2,4 triazoles

Also Published As

Publication number Publication date
LU82527A1 (fr) 1981-02-03
IL60332A (en) 1983-09-30
JPS617426B2 (es) 1986-03-06
NL182641C (nl) 1988-04-18
YU41536B (en) 1987-08-31
US4276297A (en) 1981-06-30
YU41717B (en) 1987-12-31
SE441745B (sv) 1985-11-04
DE3022302C2 (de) 1984-03-01
SE8004498L (sv) 1980-12-19
FI69842C (fi) 1986-05-26
IT8022825A0 (it) 1980-06-17
GB2053910A (en) 1981-02-11
GB2053910B (en) 1983-04-20
ATA319280A (de) 1984-01-15
DK258180A (da) 1980-12-19
FI801929A (fi) 1980-12-19
KR830002756A (ko) 1983-05-30
IE801250L (en) 1980-12-18
NL182641B (nl) 1987-11-16
ATA307583A (de) 1984-01-15
FR2459241A1 (fr) 1981-01-09
KR840002173B1 (ko) 1984-11-26
CH644375A5 (fr) 1984-07-31
DE3022302A1 (de) 1981-01-08
ES492522A0 (es) 1981-06-01
JPS565477A (en) 1981-01-20
AT375656B (de) 1984-08-27
IT1140993B (it) 1986-10-10
IL60332A0 (en) 1980-09-16
FI69842B (fi) 1985-12-31
ES498821A0 (es) 1981-12-01
PT71399A (en) 1980-07-01
BE883859A (fr) 1980-12-17
AR225766A1 (es) 1982-04-30
FR2459241B1 (es) 1983-06-17
AT375655B (de) 1984-08-27
KR840002172B1 (ko) 1984-11-26
AR227436A1 (es) 1982-10-29
NL8003496A (nl) 1980-12-22
CA1140133A (en) 1983-01-25
YU158780A (en) 1983-04-30
PH16875A (en) 1984-04-02
GR68731B (es) 1982-02-10
IE49913B1 (en) 1986-01-08
YU263382A (en) 1983-04-30
ES8201155A1 (es) 1981-12-01
KR840004687A (ko) 1984-10-22

Similar Documents

Publication Publication Date Title
EG15011A (en) Optically active 1,4-dihydropyridines,process for their preparation and their use as medicaments
DE3071888D1 (en) 4h-3,1-benzoxazin derivatives, methods for their preparation, and their use for combatting undesirable vegetation
DE3061554D1 (en) 1-vinyltriazole derivatives, process for their preparation and their use as growth regulating agents and fungicides
HUT41202A (en) Herbicidal compositions comprising 2-(2'-alkylbenzoyl)-1,3 cyclohexandione derivatives as active substance and process for preparing their active substances
PT67164B (en) Process for the preparation of hydantoin derivatives as therapeutic agents
DE2963929D1 (en) Heterocyclic derivatives of (4-(piperazin-1-yl-phenyloxymethyl)-1.3.-dioxolan-2-ylmethyl)-1h-imidazoles and -1h-1.2.4-triazoles, their preparation and use as fungicides and bactericides
EP0033655A3 (en) Imidazoline derivative, its salts, process for preparation, pharmaceutical compositions and therapeutic use, thereof
ES8201155A1 (es) Un procedimiento para la preparacion de bases de 3-ami- no-5-(4-piridil)-1,2,4-triazol
ES431497A1 (es) Procedimiento para preparar un derivado de s-triazol (1,5- a) piridina.
ZA845931B (en) 1-(4'-alkylsulphonylphenyl)-2-amino-1,3-propanediol n-substituted derivatives
IT1143921B (it) Derivati di acidi alcanoici dotati di proprieta' terapeutiche e procedimento per la loro preparazione
DE3160044D1 (en) 2,3-dihydroimidazo (1,2-b) pyridazine derivatives, process for their preparation and their therapeutical use
DE3070735D1 (en) 4-aryloxy-3-phenylpiperidine derivatives, intermediates, a process for the preparation of such compounds and their use as medicaments
DE68922053T2 (de) Pyridoindolderivate und Verfahren zu ihrer Herstellung.
IT8248610A0 (it) Prodotto farmaceutico in polvere per la terapia dell'ulcera peptica, a base di 2,4-diammino-6-(2,5-diclo rofenil)-1,3,5-triazina o dei suoi sali farmaceuticamente accettabili
PT86623A (pt) Process for the preparation of derivatives of 3-aryl-5-alkylthio-4h-1,2,4-triazoles
ES8100661A1 (es) Un procedimiento para la preparacion de 1-(3-bromo-isoxa- zol-5-il)-2-tercibutilaminoetanol
GB2055366B (en) 2-phenylimino-5-(2'-carboxyphenyl)-1,3,4-thiadiazol-4-ine derivatives useful as plant-growth regulating agents
IL57609A0 (en) Pharmaceutical agents for the treatment of sickle cell disease comprising aromatic aminoacid derivatives
EP0019190A3 (en) Fungicidal agents, process for their preparation and their use as fungicides
EP0019133A3 (en) Fungicidal agents, process for their preparation and their use as fungicides
AU490082B2 (en) Alkyl 2-nitro-5-(2' 4'dichlorophenoxy)-thiobenzoates process for preparation thereof and their use as herbicides
ZA848090B (en) N-oxalyl derivatives of n-methylcarbamates,a process for their preparation and their use as agents for combating pests
EP0294814A3 (en) Treating agents for renal diseases
IT1166217B (it) Composizione farmaceutica per la terapia delle sterilita' maschile