PT67164B - Process for the preparation of hydantoin derivatives as therapeutic agents - Google Patents
Process for the preparation of hydantoin derivatives as therapeutic agentsInfo
- Publication number
- PT67164B PT67164B PT67164A PT6716477A PT67164B PT 67164 B PT67164 B PT 67164B PT 67164 A PT67164 A PT 67164A PT 6716477 A PT6716477 A PT 6716477A PT 67164 B PT67164 B PT 67164B
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- therapeutic agents
- hydantoin derivatives
- hydantoin
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73306276A | 1976-10-18 | 1976-10-18 | |
| US05/767,803 US4117230A (en) | 1976-10-18 | 1977-02-11 | Hydantoin derivatives as therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT67164A PT67164A (en) | 1977-11-01 |
| PT67164B true PT67164B (en) | 1979-03-20 |
Family
ID=27112515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT67164A PT67164B (en) | 1976-10-18 | 1977-10-17 | Process for the preparation of hydantoin derivatives as therapeutic agents |
Country Status (29)
| Country | Link |
|---|---|
| JP (3) | JPS5353653A (en) |
| AR (1) | AR220901A1 (en) |
| AT (1) | AT356136B (en) |
| AU (1) | AU504978B2 (en) |
| BG (1) | BG28847A3 (en) |
| CA (1) | CA1088945A (en) |
| CH (1) | CH625511A5 (en) |
| DD (1) | DD131931A5 (en) |
| DE (4) | DE2759543C2 (en) |
| DK (1) | DK150302C (en) |
| ES (1) | ES463267A1 (en) |
| FI (1) | FI62307C (en) |
| FR (1) | FR2367754A1 (en) |
| GB (1) | GB1566171A (en) |
| GR (1) | GR70201B (en) |
| HK (1) | HK53881A (en) |
| IE (1) | IE45805B1 (en) |
| IL (1) | IL53094A0 (en) |
| KE (1) | KE3167A (en) |
| LU (1) | LU78330A1 (en) |
| MX (1) | MX4899E (en) |
| MY (1) | MY8200157A (en) |
| NL (1) | NL167434C (en) |
| NO (1) | NO148453C (en) |
| NZ (1) | NZ185358A (en) |
| PH (1) | PH15639A (en) |
| PT (1) | PT67164B (en) |
| SE (1) | SE437024B (en) |
| YU (1) | YU40821B (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| US4127665A (en) * | 1978-01-18 | 1978-11-28 | Pfizer Inc. | Thienohydantoin derivatives |
| US4147797A (en) * | 1978-08-11 | 1979-04-03 | Pfizer Inc. | Spiro-furanohydantoin derivatives |
| US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
| US4181728A (en) * | 1978-11-16 | 1980-01-01 | Pfizer Inc. | Spiro-polycyclicimidazolidinedione derivatives |
| US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
| US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
| US4283409A (en) * | 1979-10-29 | 1981-08-11 | Pfizer Inc. | Imidazolone derivatives |
| US4286098A (en) * | 1980-03-28 | 1981-08-25 | Pfizer Inc. | Process for the preparation of chiral hydantoins |
| JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
| ATE11781T1 (en) * | 1981-05-13 | 1985-02-15 | Imperial Chemical Industries Plc | PHARMACEUTICAL PREPARATIONS CONTAINING SPIROSUCCINIMIDE DERIVATIVES. |
| JPS58213717A (en) * | 1982-01-20 | 1983-12-12 | Eisai Co Ltd | Remedy containing hydantoin derivative |
| JPS59500617A (en) * | 1982-04-15 | 1984-04-12 | アルコン・ラボラトリ−ズ・インコ−ポレ−テッド | Hydantoin therapeutic agent |
| ZA839023B (en) * | 1982-12-06 | 1985-07-31 | Pfizer | Spiro-3-hetero-azolones for treatment of diabetic complications |
| US4474967A (en) * | 1983-04-27 | 1984-10-02 | Pfizer Inc. | 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione |
| HU198051B (en) * | 1984-10-30 | 1989-07-28 | Pfizer | Process for producing spiro square brackets open imidazolidine-4,5'(6h)-quinoline square brackets closed-2,5-dione derivatives |
| JPS61200991A (en) * | 1985-03-04 | 1986-09-05 | Sanwa Kagaku Kenkyusho:Kk | Novel spiro-3-heteroazolidine compound, production thereof, preventive and remedy for diabetic complication comprising same as active ingredient |
| US4575507A (en) * | 1985-05-29 | 1986-03-11 | Pfizer Inc. | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
| JPS6357588A (en) * | 1986-08-28 | 1988-03-12 | Sanwa Kagaku Kenkyusho Co Ltd | Hydantoin derivative, salt and, production thereof and preventing and treating, agent for diabetic complication |
| MX12896A (en) * | 1987-09-04 | 1993-06-01 | Pfizer | PROCEDURE FOR PREPARING A SPYRO-HETEROAZOLON COMPOUND |
| GB2355264A (en) | 1999-09-30 | 2001-04-18 | Merck & Co Inc | Spirohydantoin derivatives useful as alpha 1a adrenoceptor antagonists |
| WO2003088915A2 (en) | 2002-04-18 | 2003-10-30 | University Of Virginia Patent Foundation | Novel sodium channel blockers |
| FR2955107B1 (en) | 2010-01-08 | 2012-03-02 | Servier Lab | NOVEL THIOCHROMAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB818724A (en) * | 1956-10-18 | 1959-08-19 | Ici Ltd | Hydantoin derivatives |
| DE1135915B (en) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Process for the production of new, anticonvulsant spirohydantoins |
| US3532744A (en) * | 1967-07-28 | 1970-10-06 | American Home Prod | 1- and 2-amino substituted indane and tetralene carboxylic acids |
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
| DE2449030A1 (en) * | 1974-10-11 | 1976-05-20 | Schering Ag | NEW PYRIDINE DERIVATIVES |
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
-
1977
- 1977-09-30 CA CA287,868A patent/CA1088945A/en not_active Expired
- 1977-10-03 SE SE7711053A patent/SE437024B/en not_active IP Right Cessation
- 1977-10-04 GR GR54503A patent/GR70201B/el unknown
- 1977-10-05 NZ NZ185358A patent/NZ185358A/en unknown
- 1977-10-06 AU AU29431/77A patent/AU504978B2/en not_active Expired
- 1977-10-10 IL IL53094A patent/IL53094A0/en not_active IP Right Cessation
- 1977-10-10 YU YU2442/77A patent/YU40821B/en unknown
- 1977-10-14 DE DE2759543A patent/DE2759543C2/en not_active Expired
- 1977-10-14 FI FI773060A patent/FI62307C/en not_active IP Right Cessation
- 1977-10-14 DE DE2759927A patent/DE2759927C2/en not_active Expired
- 1977-10-14 DE DE2759542A patent/DE2759542C2/de not_active Expired
- 1977-10-14 PH PH20335A patent/PH15639A/en unknown
- 1977-10-14 DE DE2746244A patent/DE2746244C2/en not_active Expired
- 1977-10-15 ES ES463267A patent/ES463267A1/en not_active Expired
- 1977-10-17 CH CH1262677A patent/CH625511A5/en not_active IP Right Cessation
- 1977-10-17 MX MX776490U patent/MX4899E/en unknown
- 1977-10-17 DK DK461377A patent/DK150302C/en not_active IP Right Cessation
- 1977-10-17 NL NL7711358.A patent/NL167434C/en not_active IP Right Cessation
- 1977-10-17 NO NO773548A patent/NO148453C/en unknown
- 1977-10-17 PT PT67164A patent/PT67164B/en unknown
- 1977-10-17 LU LU78330A patent/LU78330A1/en unknown
- 1977-10-17 IE IE2114/77A patent/IE45805B1/en not_active IP Right Cessation
- 1977-10-17 FR FR7731216A patent/FR2367754A1/en active Granted
- 1977-10-17 GB GB43122/77A patent/GB1566171A/en not_active Expired
- 1977-10-17 JP JP12437177A patent/JPS5353653A/en active Granted
- 1977-10-18 BG BG037604A patent/BG28847A3/en unknown
- 1977-10-18 AT AT745977A patent/AT356136B/en not_active IP Right Cessation
- 1977-10-18 DD DD7700201582A patent/DD131931A5/en unknown
- 1977-10-18 AR AR269623A patent/AR220901A1/en active
-
1978
- 1978-11-25 JP JP53145926A patent/JPS607997B2/en not_active Expired
- 1978-11-25 JP JP53145925A patent/JPS5940388B2/en not_active Expired
-
1981
- 1981-10-09 KE KE3167A patent/KE3167A/en unknown
- 1981-11-05 HK HK538/81A patent/HK53881A/en unknown
-
1982
- 1982-12-30 MY MY157/82A patent/MY8200157A/en unknown
Also Published As
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