FI773060A - HYDANTOINDERIVAT SOM CEILING MODEL - Google Patents

HYDANTOINDERIVAT SOM CEILING MODEL

Info

Publication number
FI773060A
FI773060A FI773060A FI773060A FI773060A FI 773060 A FI773060 A FI 773060A FI 773060 A FI773060 A FI 773060A FI 773060 A FI773060 A FI 773060A FI 773060 A FI773060 A FI 773060A
Authority
FI
Finland
Prior art keywords
hydantoinderivat
som
ceiling model
ceiling
model
Prior art date
Application number
FI773060A
Other languages
Finnish (fi)
Other versions
FI62307B (en
FI62307C (en
Inventor
Reinhard Sarges
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/767,803 external-priority patent/US4117230A/en
Application filed by Pfizer filed Critical Pfizer
Publication of FI773060A publication Critical patent/FI773060A/en
Priority to FI810088A priority Critical patent/FI63579C/en
Priority to FI812208A priority patent/FI73981C/en
Publication of FI62307B publication Critical patent/FI62307B/en
Application granted granted Critical
Publication of FI62307C publication Critical patent/FI62307C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI773060A 1976-10-18 1977-10-14 FOERFARANDE FOER FRAMSTAELLNING AV SPIRO (KROMAN- ELLER -TIOKROMAN-4,4'-IMIDAZOLIDINE) -2 '5'-DIONER OCH DYLIKA TIOKROMANERS OXIDATIONSPRODUKTER VILKA AER ANVAENDBARA VID BEHANDLING AV DIABETES FI62307C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI810088A FI63579C (en) 1976-10-18 1981-01-14 PROCEDURE FOR THE FRAMEWORK OF THERAPEUTIC ANALYSIS SPIRO-BENZO (B) THIOPHENE (3,4 ') IMIDAZOLIDINE-2,5-DION-1,1-DIOXIDE
FI812208A FI73981C (en) 1976-10-18 1981-07-14 Process for the preparation of new, in the treatment of diabetes, use only spiro (imidazolidinane or hydronaphthalene) -2,5-dione derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73306276A 1976-10-18 1976-10-18
US73306276 1976-10-18
US76780377 1977-02-11
US05/767,803 US4117230A (en) 1976-10-18 1977-02-11 Hydantoin derivatives as therapeutic agents

Publications (3)

Publication Number Publication Date
FI773060A true FI773060A (en) 1978-04-19
FI62307B FI62307B (en) 1982-08-31
FI62307C FI62307C (en) 1982-12-10

Family

ID=27112515

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773060A FI62307C (en) 1976-10-18 1977-10-14 FOERFARANDE FOER FRAMSTAELLNING AV SPIRO (KROMAN- ELLER -TIOKROMAN-4,4'-IMIDAZOLIDINE) -2 '5'-DIONER OCH DYLIKA TIOKROMANERS OXIDATIONSPRODUKTER VILKA AER ANVAENDBARA VID BEHANDLING AV DIABETES

Country Status (29)

Country Link
JP (3) JPS5353653A (en)
AR (1) AR220901A1 (en)
AT (1) AT356136B (en)
AU (1) AU504978B2 (en)
BG (1) BG28847A3 (en)
CA (1) CA1088945A (en)
CH (1) CH625511A5 (en)
DD (1) DD131931A5 (en)
DE (4) DE2759927C2 (en)
DK (1) DK150302C (en)
ES (1) ES463267A1 (en)
FI (1) FI62307C (en)
FR (1) FR2367754A1 (en)
GB (1) GB1566171A (en)
GR (1) GR70201B (en)
HK (1) HK53881A (en)
IE (1) IE45805B1 (en)
IL (1) IL53094A0 (en)
KE (1) KE3167A (en)
LU (1) LU78330A1 (en)
MX (1) MX4899E (en)
MY (1) MY8200157A (en)
NL (1) NL167434C (en)
NO (1) NO148453C (en)
NZ (1) NZ185358A (en)
PH (1) PH15639A (en)
PT (1) PT67164B (en)
SE (1) SE437024B (en)
YU (1) YU40821B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4127665A (en) * 1978-01-18 1978-11-28 Pfizer Inc. Thienohydantoin derivatives
US4147797A (en) * 1978-08-11 1979-04-03 Pfizer Inc. Spiro-furanohydantoin derivatives
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones
US4181728A (en) * 1978-11-16 1980-01-01 Pfizer Inc. Spiro-polycyclicimidazolidinedione derivatives
US4181729A (en) * 1979-03-21 1980-01-01 Pfizer Inc. Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives
US4235911A (en) * 1979-06-13 1980-11-25 Pfizer Inc. Hydantoin derivatives
US4283409A (en) * 1979-10-29 1981-08-11 Pfizer Inc. Imidazolone derivatives
US4286098A (en) * 1980-03-28 1981-08-25 Pfizer Inc. Process for the preparation of chiral hydantoins
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
EP0065392B1 (en) * 1981-05-13 1985-02-13 Imperial Chemical Industries Plc Pharmaceutical compositions containing spiro succinimide derivatives
JPS58213717A (en) * 1982-01-20 1983-12-12 Eisai Co Ltd Remedy containing hydantoin derivative
JPS59500617A (en) * 1982-04-15 1984-04-12 アルコン・ラボラトリ−ズ・インコ−ポレ−テッド Hydantoin therapeutic agent
ZA839023B (en) * 1982-12-06 1985-07-31 Pfizer Spiro-3-hetero-azolones for treatment of diabetic complications
US4474967A (en) * 1983-04-27 1984-10-02 Pfizer Inc. 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione
HU198051B (en) * 1984-10-30 1989-07-28 Pfizer Process for producing spiro square brackets open imidazolidine-4,5'(6h)-quinoline square brackets closed-2,5-dione derivatives
JPS61200991A (en) * 1985-03-04 1986-09-05 Sanwa Kagaku Kenkyusho:Kk Novel spiro-3-heteroazolidine compound, production thereof, preventive and remedy for diabetic complication comprising same as active ingredient
US4575507A (en) * 1985-05-29 1986-03-11 Pfizer Inc. Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use
JPS6357588A (en) * 1986-08-28 1988-03-12 Sanwa Kagaku Kenkyusho Co Ltd Hydantoin derivative, salt and, production thereof and preventing and treating, agent for diabetic complication
HU204832B (en) * 1987-09-04 1992-02-28 Pfizer Process for producing spiro-(imidazolidine-4,4'-pyrano/2,3-b/pyridine) derivatives and pharmaceutical compositions comprising same
GB2355264A (en) 1999-09-30 2001-04-18 Merck & Co Inc Spirohydantoin derivatives useful as alpha 1a adrenoceptor antagonists
WO2003088915A2 (en) * 2002-04-18 2003-10-30 University Of Virginia Patent Foundation Novel sodium channel blockers
FR2955107B1 (en) 2010-01-08 2012-03-02 Servier Lab NOVEL THIOCHROMAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB818724A (en) * 1956-10-18 1959-08-19 Ici Ltd Hydantoin derivatives
DE1135915B (en) * 1961-06-29 1962-09-06 Asta Werke Ag Chem Fab Process for the production of new, anticonvulsant spirohydantoins
US3532744A (en) * 1967-07-28 1970-10-06 American Home Prod 1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
DE2449030A1 (en) * 1974-10-11 1976-05-20 Schering Ag NEW PYRIDINE DERIVATIVES
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents

Also Published As

Publication number Publication date
NL167434C (en) 1981-12-16
HK53881A (en) 1981-11-13
JPS5495575A (en) 1979-07-28
NL7711358A (en) 1978-04-20
FI62307B (en) 1982-08-31
JPS607997B2 (en) 1985-02-28
JPS5940388B2 (en) 1984-09-29
JPS5495570A (en) 1979-07-28
IE45805L (en) 1978-04-18
LU78330A1 (en) 1979-06-01
MY8200157A (en) 1982-12-31
FI62307C (en) 1982-12-10
MX4899E (en) 1982-12-14
ATA745977A (en) 1979-09-15
DK461377A (en) 1978-04-19
NO148453B (en) 1983-07-04
CH625511A5 (en) 1981-09-30
PT67164B (en) 1979-03-20
DK150302B (en) 1987-02-02
AU2943177A (en) 1979-04-12
CA1088945A (en) 1980-11-04
DE2746244C2 (en) 1983-05-19
AR220901A1 (en) 1980-12-15
DE2759543C2 (en) 1987-04-09
JPS5353653A (en) 1978-05-16
FR2367754A1 (en) 1978-05-12
ES463267A1 (en) 1978-07-16
IL53094A0 (en) 1977-12-30
SE437024B (en) 1985-02-04
PH15639A (en) 1983-03-11
FR2367754B1 (en) 1982-07-09
AU504978B2 (en) 1979-11-01
DD131931A5 (en) 1978-08-09
DE2759927C2 (en) 1986-12-04
GB1566171A (en) 1980-04-30
DE2746244A1 (en) 1978-04-20
IE45805B1 (en) 1982-12-01
NO148453C (en) 1983-10-12
NL167434B (en) 1981-07-16
YU40821B (en) 1986-06-30
SE7711053L (en) 1978-04-19
GR70201B (en) 1982-08-31
DK150302C (en) 1987-09-28
KE3167A (en) 1981-11-06
PT67164A (en) 1977-11-01
YU244277A (en) 1982-08-31
BG28847A3 (en) 1980-07-15
AT356136B (en) 1980-04-10
NZ185358A (en) 1979-06-08
DE2759542C2 (en) 1988-07-07
JPS5534132B2 (en) 1980-09-04
NO773548L (en) 1978-04-19

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Legal Events

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MM Patent lapsed
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Owner name: PFIZER INC.