DK461377A - R PROCEDURE FOR MAKING SPIROHYDANTOIN COMPOUND - Google Patents
R PROCEDURE FOR MAKING SPIROHYDANTOIN COMPOUNDInfo
- Publication number
- DK461377A DK461377A DK461377A DK461377A DK461377A DK 461377 A DK461377 A DK 461377A DK 461377 A DK461377 A DK 461377A DK 461377 A DK461377 A DK 461377A DK 461377 A DK461377 A DK 461377A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- making
- spirohydantoin
- compound
- spirohydantoin compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73306276A | 1976-10-18 | 1976-10-18 | |
| US73306276 | 1976-10-18 | ||
| US05/767,803 US4117230A (en) | 1976-10-18 | 1977-02-11 | Hydantoin derivatives as therapeutic agents |
| US76780377 | 1977-02-11 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK461377A true DK461377A (en) | 1978-04-19 |
| DK150302B DK150302B (en) | 1987-02-02 |
| DK150302C DK150302C (en) | 1987-09-28 |
Family
ID=27112515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK461377A DK150302C (en) | 1976-10-18 | 1977-10-17 | METHOD OF ANALOGUE FOR THE PREPARATION OF SPIRO-HYDANTOIN COMPOUNDS OR PHARMACOLOGICAL ACCEPTABLE BASES |
Country Status (29)
| Country | Link |
|---|---|
| JP (3) | JPS5353653A (en) |
| AR (1) | AR220901A1 (en) |
| AT (1) | AT356136B (en) |
| AU (1) | AU504978B2 (en) |
| BG (1) | BG28847A3 (en) |
| CA (1) | CA1088945A (en) |
| CH (1) | CH625511A5 (en) |
| DD (1) | DD131931A5 (en) |
| DE (4) | DE2759542C2 (en) |
| DK (1) | DK150302C (en) |
| ES (1) | ES463267A1 (en) |
| FI (1) | FI62307C (en) |
| FR (1) | FR2367754A1 (en) |
| GB (1) | GB1566171A (en) |
| GR (1) | GR70201B (en) |
| HK (1) | HK53881A (en) |
| IE (1) | IE45805B1 (en) |
| IL (1) | IL53094A0 (en) |
| KE (1) | KE3167A (en) |
| LU (1) | LU78330A1 (en) |
| MX (1) | MX4899E (en) |
| MY (1) | MY8200157A (en) |
| NL (1) | NL167434C (en) |
| NO (1) | NO148453C (en) |
| NZ (1) | NZ185358A (en) |
| PH (1) | PH15639A (en) |
| PT (1) | PT67164B (en) |
| SE (1) | SE437024B (en) |
| YU (1) | YU40821B (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| US4127665A (en) * | 1978-01-18 | 1978-11-28 | Pfizer Inc. | Thienohydantoin derivatives |
| US4147797A (en) * | 1978-08-11 | 1979-04-03 | Pfizer Inc. | Spiro-furanohydantoin derivatives |
| US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
| US4181728A (en) * | 1978-11-16 | 1980-01-01 | Pfizer Inc. | Spiro-polycyclicimidazolidinedione derivatives |
| US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
| US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
| US4283409A (en) * | 1979-10-29 | 1981-08-11 | Pfizer Inc. | Imidazolone derivatives |
| US4286098A (en) * | 1980-03-28 | 1981-08-25 | Pfizer Inc. | Process for the preparation of chiral hydantoins |
| JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
| EP0065392B1 (en) * | 1981-05-13 | 1985-02-13 | Imperial Chemical Industries Plc | Pharmaceutical compositions containing spiro succinimide derivatives |
| JPS58213717A (en) * | 1982-01-20 | 1983-12-12 | Eisai Co Ltd | Remedy containing hydantoin derivative |
| JPS59500617A (en) * | 1982-04-15 | 1984-04-12 | アルコン・ラボラトリ−ズ・インコ−ポレ−テッド | Hydantoin therapeutic agent |
| HU193191B (en) * | 1982-12-06 | 1987-08-28 | Pfizer | Process for preparing spiro-hetero-azolones |
| US4474967A (en) * | 1983-04-27 | 1984-10-02 | Pfizer Inc. | 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione |
| WO1986002647A1 (en) * | 1984-10-30 | 1986-05-09 | Pfizer Inc. | Spiro-heteroazolones for treatment of diabetes complications |
| JPS61200991A (en) * | 1985-03-04 | 1986-09-05 | Sanwa Kagaku Kenkyusho:Kk | Novel spiro-3-heteroazolidine compound, production thereof, preventive and remedy for diabetic complication comprising same as active ingredient |
| US4575507A (en) * | 1985-05-29 | 1986-03-11 | Pfizer Inc. | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
| JPS6357588A (en) * | 1986-08-28 | 1988-03-12 | Sanwa Kagaku Kenkyusho Co Ltd | Hydantoin derivative, salt and, production thereof and preventing and treating, agent for diabetic complication |
| HU204832B (en) * | 1987-09-04 | 1992-02-28 | Pfizer | Process for producing spiro-(imidazolidine-4,4'-pyrano/2,3-b/pyridine) derivatives and pharmaceutical compositions comprising same |
| GB2355264A (en) | 1999-09-30 | 2001-04-18 | Merck & Co Inc | Spirohydantoin derivatives useful as alpha 1a adrenoceptor antagonists |
| JP2005523314A (en) | 2002-04-18 | 2005-08-04 | ユニバーシティ オブ バージニア パテント ファウンデーション | Novel sodium channel blocking compounds |
| FR2955107B1 (en) | 2010-01-08 | 2012-03-02 | Servier Lab | NOVEL THIOCHROMAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB818724A (en) * | 1956-10-18 | 1959-08-19 | Ici Ltd | Hydantoin derivatives |
| DE1135915B (en) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Process for the production of new, anticonvulsant spirohydantoins |
| US3532744A (en) * | 1967-07-28 | 1970-10-06 | American Home Prod | 1- and 2-amino substituted indane and tetralene carboxylic acids |
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
| DE2449030A1 (en) * | 1974-10-11 | 1976-05-20 | Schering Ag | NEW PYRIDINE DERIVATIVES |
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
-
1977
- 1977-09-30 CA CA287,868A patent/CA1088945A/en not_active Expired
- 1977-10-03 SE SE7711053A patent/SE437024B/en not_active IP Right Cessation
- 1977-10-04 GR GR54503A patent/GR70201B/el unknown
- 1977-10-05 NZ NZ185358A patent/NZ185358A/en unknown
- 1977-10-06 AU AU29431/77A patent/AU504978B2/en not_active Expired
- 1977-10-10 YU YU2442/77A patent/YU40821B/en unknown
- 1977-10-10 IL IL53094A patent/IL53094A0/en not_active IP Right Cessation
- 1977-10-14 DE DE2759542A patent/DE2759542C2/de not_active Expired
- 1977-10-14 PH PH20335A patent/PH15639A/en unknown
- 1977-10-14 FI FI773060A patent/FI62307C/en not_active IP Right Cessation
- 1977-10-14 DE DE2746244A patent/DE2746244C2/en not_active Expired
- 1977-10-14 DE DE2759543A patent/DE2759543C2/de not_active Expired
- 1977-10-14 DE DE2759927A patent/DE2759927C2/en not_active Expired
- 1977-10-15 ES ES463267A patent/ES463267A1/en not_active Expired
- 1977-10-17 FR FR7731216A patent/FR2367754A1/en active Granted
- 1977-10-17 JP JP12437177A patent/JPS5353653A/en active Granted
- 1977-10-17 PT PT67164A patent/PT67164B/en unknown
- 1977-10-17 CH CH1262677A patent/CH625511A5/en not_active IP Right Cessation
- 1977-10-17 NL NL7711358.A patent/NL167434C/en not_active IP Right Cessation
- 1977-10-17 MX MX776490U patent/MX4899E/en unknown
- 1977-10-17 IE IE2114/77A patent/IE45805B1/en not_active IP Right Cessation
- 1977-10-17 LU LU78330A patent/LU78330A1/en unknown
- 1977-10-17 NO NO773548A patent/NO148453C/en unknown
- 1977-10-17 DK DK461377A patent/DK150302C/en not_active IP Right Cessation
- 1977-10-17 GB GB43122/77A patent/GB1566171A/en not_active Expired
- 1977-10-18 AR AR269623A patent/AR220901A1/en active
- 1977-10-18 DD DD7700201582A patent/DD131931A5/en unknown
- 1977-10-18 BG BG7737604A patent/BG28847A3/en unknown
- 1977-10-18 AT AT745977A patent/AT356136B/en not_active IP Right Cessation
-
1978
- 1978-11-25 JP JP53145926A patent/JPS607997B2/en not_active Expired
- 1978-11-25 JP JP53145925A patent/JPS5940388B2/en not_active Expired
-
1981
- 1981-10-09 KE KE3167A patent/KE3167A/en unknown
- 1981-11-05 HK HK538/81A patent/HK53881A/en unknown
-
1982
- 1982-12-30 MY MY157/82A patent/MY8200157A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |