FI68762C - Pressfoerfarande foer framstaellning av suppositorier - Google Patents
Pressfoerfarande foer framstaellning av suppositorier Download PDFInfo
- Publication number
- FI68762C FI68762C FI792927A FI792927A FI68762C FI 68762 C FI68762 C FI 68762C FI 792927 A FI792927 A FI 792927A FI 792927 A FI792927 A FI 792927A FI 68762 C FI68762 C FI 68762C
- Authority
- FI
- Finland
- Prior art keywords
- suppositories
- temperature
- suppository
- compression method
- compression
- Prior art date
Links
- 239000000829 suppository Substances 0.000 claims description 51
- 238000007906 compression Methods 0.000 claims description 18
- 230000006835 compression Effects 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 13
- 150000001875 compounds Chemical class 0.000 claims description 10
- 239000011230 binding agent Substances 0.000 claims description 9
- 239000008187 granular material Substances 0.000 claims description 6
- 238000003825 pressing Methods 0.000 claims description 6
- 239000002511 suppository base Substances 0.000 claims description 6
- 229960003133 ergot alkaloid Drugs 0.000 claims description 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000004519 grease Substances 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 description 9
- UZVHFVZFNXBMQJ-UHFFFAOYSA-N butalbital Chemical compound CC(C)CC1(CC=C)C(=O)NC(=O)NC1=O UZVHFVZFNXBMQJ-UHFFFAOYSA-N 0.000 description 6
- 229960002546 butalbital Drugs 0.000 description 6
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 6
- 229960001948 caffeine Drugs 0.000 description 5
- PXWLVJLKJGVOKE-UHFFFAOYSA-N propyphenazone Chemical compound O=C1C(C(C)C)=C(C)N(C)N1C1=CC=CC=C1 PXWLVJLKJGVOKE-UHFFFAOYSA-N 0.000 description 5
- 229960002189 propyphenazone Drugs 0.000 description 5
- -1 Teflon Chemical class 0.000 description 4
- 239000013543 active substance Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 239000000729 antidote Substances 0.000 description 2
- 229940075522 antidotes Drugs 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 238000004049 embossing Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- JTIGKVIOEQASGT-UHFFFAOYSA-N proquazone Chemical compound N=1C(=O)N(C(C)C)C2=CC(C)=CC=C2C=1C1=CC=CC=C1 JTIGKVIOEQASGT-UHFFFAOYSA-N 0.000 description 2
- 229960002466 proquazone Drugs 0.000 description 2
- 229940125723 sedative agent Drugs 0.000 description 2
- 239000000932 sedative agent Substances 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- FMBVHKPWDJQLNO-UHFFFAOYSA-N 1-[(3-fluorophenyl)methyl]-5-nitroindazole Chemical compound N1=CC2=CC([N+](=O)[O-])=CC=C2N1CC1=CC=CC(F)=C1 FMBVHKPWDJQLNO-UHFFFAOYSA-N 0.000 description 1
- DBGSRZSKGVSXRK-UHFFFAOYSA-N 1-[2-[5-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]-1,3,4-oxadiazol-2-yl]acetyl]-3,6-dihydro-2H-pyridine-4-carboxylic acid Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C1=NN=C(O1)CC(=O)N1CCC(=CC1)C(=O)O DBGSRZSKGVSXRK-UHFFFAOYSA-N 0.000 description 1
- AGNTUZCMJBTHOG-UHFFFAOYSA-N 3-[3-(2,3-dihydroxypropoxy)-2-hydroxypropoxy]propane-1,2-diol Chemical class OCC(O)COCC(O)COCC(O)CO AGNTUZCMJBTHOG-UHFFFAOYSA-N 0.000 description 1
- LBFGQUCAQWAFNN-UHFFFAOYSA-N 4-ethyl-2-(1-methylpiperidin-4-yl)-5-phenyl-1h-pyrazol-3-one Chemical compound O=C1C(CC)=C(C=2C=CC=CC=2)NN1C1CCN(C)CC1 LBFGQUCAQWAFNN-UHFFFAOYSA-N 0.000 description 1
- VCCNKWWXYVWTLT-CYZBKYQRSA-N 7-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one Chemical compound C1=C(O)C(OC)=CC=C1C(OC1=C2)=CC(=O)C1=C(O)C=C2O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 VCCNKWWXYVWTLT-CYZBKYQRSA-N 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical class CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- QZXATCCPQKOEIH-UHFFFAOYSA-N Florasulam Chemical compound N=1N2C(OC)=NC=C(F)C2=NC=1S(=O)(=O)NC1=C(F)C=CC=C1F QZXATCCPQKOEIH-UHFFFAOYSA-N 0.000 description 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000002921 anti-spasmodic effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229940125715 antihistaminic agent Drugs 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- VEQOALNAAJBPNY-UHFFFAOYSA-N antipyrine Chemical class CN1C(C)=CC(=O)N1C1=CC=CC=C1 VEQOALNAAJBPNY-UHFFFAOYSA-N 0.000 description 1
- 229940124575 antispasmodic agent Drugs 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 229940125717 barbiturate Drugs 0.000 description 1
- 229940092732 belladonna alkaloid Drugs 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- GERIGMSHTUAXSI-UHFFFAOYSA-N bis(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 4-phenyl-2,3-dihydro-1h-naphthalene-1,4-dicarboxylate Chemical compound CN1C(C2)CCC1CC2OC(=O)C(C1=CC=CC=C11)CCC1(C(=O)OC1CC2CCC(N2C)C1)C1=CC=CC=C1 GERIGMSHTUAXSI-UHFFFAOYSA-N 0.000 description 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229960004704 dihydroergotamine Drugs 0.000 description 1
- HESHRHUZIWVEAJ-JGRZULCMSA-N dihydroergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2[C@@H](C3=CC=CC4=NC=C([C]34)C2)C1)C)C1=CC=CC=C1 HESHRHUZIWVEAJ-JGRZULCMSA-N 0.000 description 1
- ADYPXRFPBQGGAH-UMYZUSPBSA-N dihydroergotamine mesylate Chemical compound CS(O)(=O)=O.C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC=C(C=34)C2)C1)C)C1=CC=CC=C1 ADYPXRFPBQGGAH-UMYZUSPBSA-N 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000007908 dry granulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229960004943 ergotamine Drugs 0.000 description 1
- OFKDAAIKGIBASY-VFGNJEKYSA-N ergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2C(C3=CC=CC4=NC=C([C]34)C2)=C1)C)C1=CC=CC=C1 OFKDAAIKGIBASY-VFGNJEKYSA-N 0.000 description 1
- 229960001903 ergotamine tartrate Drugs 0.000 description 1
- XCGSFFUVFURLIX-UHFFFAOYSA-N ergotaminine Natural products C1=C(C=2C=CC=C3NC=C(C=23)C2)C2N(C)CC1C(=O)NC(C(N12)=O)(C)OC1(O)C1CCCN1C(=O)C2CC1=CC=CC=C1 XCGSFFUVFURLIX-UHFFFAOYSA-N 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000004898 kneading Methods 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229950001532 piperylone Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 150000003246 quinazolines Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/08—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Auxiliary Devices For And Details Of Packaging Control (AREA)
- Basic Packing Technique (AREA)
- Fodder In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1019478A CH637014A5 (de) | 1978-09-29 | 1978-09-29 | Verfahren zur herstellung von suppositorien. |
| CH1019478 | 1978-09-29 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI792927A7 FI792927A7 (fi) | 1980-03-30 |
| FI68762B FI68762B (fi) | 1985-07-31 |
| FI68762C true FI68762C (fi) | 1985-11-11 |
Family
ID=4360430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI792927A FI68762C (fi) | 1978-09-29 | 1979-09-20 | Pressfoerfarande foer framstaellning av suppositorier |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4369784A (cs) |
| JP (1) | JPS5549310A (cs) |
| KR (1) | KR830000308B1 (cs) |
| AR (1) | AR228729A1 (cs) |
| AT (1) | AT374680B (cs) |
| AU (1) | AU530954B2 (cs) |
| BE (1) | BE875506A (cs) |
| CA (1) | CA1134268A (cs) |
| CH (1) | CH637014A5 (cs) |
| CS (1) | CS219258B2 (cs) |
| DD (1) | DD146248A5 (cs) |
| DE (1) | DE2914163C2 (cs) |
| DK (1) | DK393379A (cs) |
| ES (1) | ES479565A1 (cs) |
| FI (1) | FI68762C (cs) |
| FR (1) | FR2437204B1 (cs) |
| GB (1) | GB2030861B (cs) |
| HU (1) | HU180291B (cs) |
| IE (1) | IE48405B1 (cs) |
| IL (1) | IL58342A (cs) |
| IT (1) | IT1116178B (cs) |
| NL (1) | NL7903065A (cs) |
| NO (1) | NO153553C (cs) |
| NZ (1) | NZ191674A (cs) |
| PH (1) | PH16955A (cs) |
| PT (1) | PT70234A (cs) |
| SE (1) | SE439243B (cs) |
| ZA (1) | ZA795180B (cs) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4483807A (en) * | 1981-01-27 | 1984-11-20 | Japan Atomic Energy Research Institute | Process for producing a slow release composite |
| US5137669A (en) * | 1988-03-02 | 1992-08-11 | Endocon, Inc. | Manufacture of partially fused peptide pellet |
| KR100354702B1 (ko) | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
| US5891471A (en) | 1993-11-23 | 1999-04-06 | Euro-Celtique, S.A. | Pharmaceutical multiparticulates |
| US5843480A (en) | 1994-03-14 | 1998-12-01 | Euro-Celtique, S.A. | Controlled release diamorphine formulation |
| GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| ATE199517T1 (de) * | 1995-12-12 | 2001-03-15 | Alusuisse Tech & Man Ag | Verfahren zum herstellen von blisterverpackungen |
| DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
| GB0015617D0 (en) * | 2000-06-26 | 2000-08-16 | Vectura Ltd | Improved preparations for dermal delivery of active substances |
| JP2003095923A (ja) * | 2001-09-26 | 2003-04-03 | Tendou Seiyaku Kk | 油脂類成形物の製造法 |
| EP1506035A1 (en) * | 2002-05-06 | 2005-02-16 | Vectura Limited | Application device for topical administration of pharmaceutical agents |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2307371A (en) * | 1941-08-13 | 1943-01-05 | Ray O Vac Co | Molding process |
| US2874417A (en) * | 1954-06-28 | 1959-02-24 | Elektrokemisk As | Method of forming thermoplastic briquettes |
| DE2553026A1 (de) * | 1974-12-04 | 1976-06-10 | Schlueter Edelfett | Neue formulierungen |
| SU572269A1 (ru) * | 1975-07-14 | 1977-09-15 | Львовский государственный медицинский институт | Способ получени суппозиториев |
| DE2551446B2 (de) * | 1975-11-15 | 1977-09-15 | Karl Werner Schlüter GmbH, 2000 Ham burg | Verfahren zur herstellung von suppositorien |
| DE2556561C2 (de) * | 1975-12-16 | 1983-04-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von porösen Tabletten |
-
1978
- 1978-09-29 CH CH1019478A patent/CH637014A5/de not_active IP Right Cessation
-
1979
- 1979-04-05 GB GB7911927A patent/GB2030861B/en not_active Expired
- 1979-04-07 DE DE2914163A patent/DE2914163C2/de not_active Expired
- 1979-04-09 IT IT48667/79A patent/IT1116178B/it active
- 1979-04-11 AT AT0269979A patent/AT374680B/de active
- 1979-04-11 BE BE0/194551A patent/BE875506A/xx not_active IP Right Cessation
- 1979-04-11 ES ES479565A patent/ES479565A1/es not_active Expired
- 1979-04-11 FR FR797909158A patent/FR2437204B1/fr not_active Expired
- 1979-04-19 NL NL7903065A patent/NL7903065A/nl not_active Application Discontinuation
- 1979-04-25 JP JP5199779A patent/JPS5549310A/ja active Granted
- 1979-09-20 SE SE7907795A patent/SE439243B/sv not_active IP Right Cessation
- 1979-09-20 DK DK393379A patent/DK393379A/da not_active Application Discontinuation
- 1979-09-20 FI FI792927A patent/FI68762C/fi not_active IP Right Cessation
- 1979-09-21 NO NO793034A patent/NO153553C/no unknown
- 1979-09-26 NZ NZ191674A patent/NZ191674A/xx unknown
- 1979-09-27 IL IL58342A patent/IL58342A/xx unknown
- 1979-09-27 IE IE1842/79A patent/IE48405B1/en unknown
- 1979-09-27 PT PT70234A patent/PT70234A/pt unknown
- 1979-09-27 CA CA336,504A patent/CA1134268A/en not_active Expired
- 1979-09-28 AU AU51287/79A patent/AU530954B2/en not_active Ceased
- 1979-09-28 PH PH23076A patent/PH16955A/en unknown
- 1979-09-28 AR AR278252A patent/AR228729A1/es active
- 1979-09-28 HU HU79SA3201A patent/HU180291B/hu unknown
- 1979-09-28 DD DD79215888A patent/DD146248A5/de unknown
- 1979-09-28 CS CS796590A patent/CS219258B2/cs unknown
- 1979-09-28 KR KR1019790003364A patent/KR830000308B1/ko not_active Expired
- 1979-09-28 ZA ZA00795180A patent/ZA795180B/xx unknown
-
1980
- 1980-12-09 US US06/214,747 patent/US4369784A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI68762C (fi) | Pressfoerfarande foer framstaellning av suppositorier | |
| US4483847A (en) | Process for the manufacture of a pharmaceutical composition with a retarded liberation of active material | |
| RU2204996C2 (ru) | Таблетка, быстро распадающаяся в щечном кармане, и способ ее изготовления | |
| US3279998A (en) | Method of preparing sustained release tablets | |
| KR20010030839A (ko) | 니트로글리세린 압축 정제 및 그의 제조 방법 | |
| IE913592A1 (en) | Solvent-free pharmaceutical formulation to be administered orally having delayed release of active ingredient and process for its preparation | |
| JPWO2010021300A1 (ja) | 新規マンニトール打錠用賦形剤 | |
| ES2639547T3 (es) | Método para producir un comprimido de matriz de cera-citrato de potasio de liberación prolongada | |
| JP2003518486A (ja) | トラマドール・ハイドロクロライドを含む放出の調整された医薬組成物およびその調製方法 | |
| JP2006131575A (ja) | 低融点薬剤含有顆粒、およびこれを用いて製造した錠剤 | |
| WO2007018057A1 (ja) | 口腔内速崩壊錠およびその製造法 | |
| FI87314C (fi) | Foerfarande foer framstaellning av pillerprodukt med laong verkan | |
| JP4063390B2 (ja) | 錠剤の製造方法 | |
| RU2183119C1 (ru) | Фармацевтическая композиция, обладающая спазмолитической активностью, способ ее получения | |
| JPS6236173A (ja) | 固形成型物およびその製造法 | |
| JP2013256480A (ja) | タンニン酸ベルベリン粒子及びその製造方法、錠剤 | |
| CA2201040A1 (en) | Solid pharmaceutical preparation, comprising 5-methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide | |
| JP2007332074A (ja) | 口腔内速崩壊錠およびその製造方法 | |
| JP2004517111A (ja) | シタロプラムを含有する薬学的調合物 | |
| KR101509489B1 (ko) | 발사르탄을 함유하는 고형 경구제형의 제조 방법 | |
| CN104784137B (zh) | 一种含有苯磺酸氨氯地平左旋体或消旋体的片剂及其制备方法 | |
| JPH04202131A (ja) | 長期間安定な経口用医薬製剤 | |
| RU2203056C1 (ru) | Способ получения твердой лекарственной формы препарата на основе дибазола | |
| CN1989962B (zh) | 一种含有莫吉司坦的胶囊剂 | |
| CN111494326A (zh) | 一种阿哌沙班片及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: SANDOZ AG |