FI68359C - Foerfarande foer framstaellning av en stabil prostacyklinkomposition foer terapeutiskt anvaendning - Google Patents

Foerfarande foer framstaellning av en stabil prostacyklinkomposition foer terapeutiskt anvaendning Download PDF

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Publication number
FI68359C
FI68359C FI791565A FI791565A FI68359C FI 68359 C FI68359 C FI 68359C FI 791565 A FI791565 A FI 791565A FI 791565 A FI791565 A FI 791565A FI 68359 C FI68359 C FI 68359C
Authority
FI
Finland
Prior art keywords
solution
buffer
prostacyclin
active compound
sodium
Prior art date
Application number
FI791565A
Other languages
English (en)
Finnish (fi)
Other versions
FI791565A (fi
FI68359B (fi
Inventor
Ian Seymour Watts
Peter Hugh Marsden
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI791565A publication Critical patent/FI791565A/fi
Application granted granted Critical
Publication of FI68359B publication Critical patent/FI68359B/fi
Publication of FI68359C publication Critical patent/FI68359C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI791565A 1978-05-17 1979-05-16 Foerfarande foer framstaellning av en stabil prostacyklinkomposition foer terapeutiskt anvaendning FI68359C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2017578 1978-05-17
GB2017578 1978-05-17

Publications (3)

Publication Number Publication Date
FI791565A FI791565A (fi) 1979-11-18
FI68359B FI68359B (fi) 1985-05-31
FI68359C true FI68359C (fi) 1985-09-10

Family

ID=10141640

Family Applications (1)

Application Number Title Priority Date Filing Date
FI791565A FI68359C (fi) 1978-05-17 1979-05-16 Foerfarande foer framstaellning av en stabil prostacyklinkomposition foer terapeutiskt anvaendning

Country Status (28)

Country Link
US (1) US4335139A (xx)
EP (1) EP0005768B1 (xx)
JP (1) JPS54163809A (xx)
KR (1) KR830000527B1 (xx)
AT (2) AT365926B (xx)
AU (1) AU525695B2 (xx)
BE (1) BE876296A (xx)
CA (1) CA1141661A (xx)
CH (1) CH641044A5 (xx)
CS (1) CS214798B2 (xx)
DE (2) DE2920020A1 (xx)
DK (1) DK156004C (xx)
ES (1) ES480597A1 (xx)
FI (1) FI68359C (xx)
FR (1) FR2425856A1 (xx)
GR (1) GR68452B (xx)
HU (1) HU182746B (xx)
IL (1) IL57298A (xx)
IT (1) IT1116840B (xx)
LU (1) LU81272A1 (xx)
MC (1) MC1265A1 (xx)
NL (1) NL7903871A (xx)
NZ (1) NZ190462A (xx)
PH (1) PH15850A (xx)
PL (1) PL134004B1 (xx)
SE (1) SE450930B (xx)
SU (1) SU978715A3 (xx)
ZA (1) ZA787353B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3010002A1 (de) * 1980-03-15 1981-10-01 Hoechst Ag, 6000 Frankfurt Prostaglandine enthaltende pharmazeutische zubereitung
GB8814438D0 (en) * 1988-06-17 1988-07-20 Wellcome Found Compounds for use in medicine
MY106300A (en) * 1988-06-17 1995-04-29 The Wellcome Foundation Ltd Prostaglandin analoques for use in medicine
JP3421330B2 (ja) * 2000-11-02 2003-06-30 持田製薬株式会社 ビダラビン注射用乾燥製剤
EP1238670A1 (en) * 2001-03-07 2002-09-11 Bruce Daniels Composition and method for treating and preventing cardiovascular disease and hypertension.
US7491263B2 (en) 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
DE602006005423D1 (de) * 2005-06-29 2009-04-16 Verisfield Uk Ltd Pharmazeutische Zusammensetzungen von Risperidon in wässriger Lösung
BRPI0707488B8 (pt) 2006-02-03 2021-05-25 Actelion One Sa método para a produção de uma composição de epoprostenol, composição farmacêutica e solução estável
KR101693049B1 (ko) * 2007-09-07 2017-01-04 유나이티드 세러퓨틱스 코오포레이션 그람 음성 박테리아에 대한 선택적인 살균 활성을 갖는 완충 용액 및 이의 이용방법
HU231031B1 (hu) 2016-03-23 2019-12-30 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Megnövelt stabilitású epoprostenol nátrium és eljárás előállítására
DE202024100435U1 (de) 2023-02-14 2024-02-22 Tomasz Dąbrowski Zaunfeld zum Aufbau einer Reitbande

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036954A (en) 1973-11-02 1977-07-19 Yamanouchi Pharmaceutical Co., Ltd. Stable prostaglandin E group-containing formulation
GB1504437A (en) 1974-03-08 1978-03-22 Dunlop Ltd Rubberplastics composites
DE2515001C2 (de) * 1975-04-04 1986-10-02 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandin enthaltende gefriergetrocknete Pulver
US3997587A (en) 1975-06-26 1976-12-14 Syntex (U.S.A.) Inc. D1- and 8R-9-fluoro-prostadienoic acid derivatives
US4005133A (en) 1975-10-14 1977-01-25 The Upjohn Company PGF2.sub.α, L-Arginine salt
FR2351112A1 (fr) * 1975-10-21 1977-12-09 Wellcome Found Derive de prostaglandine et medicament contenant ce derive
US4062964A (en) 1975-12-03 1977-12-13 Ciba-Geigy Corporation Antifertility-combinations
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
JPS542335A (en) * 1977-05-20 1979-01-09 Wellcome Found Medical composition

Also Published As

Publication number Publication date
DE2966046D1 (en) 1983-09-15
SU978715A3 (ru) 1982-11-30
AU4704279A (en) 1979-11-22
US4335139A (en) 1982-06-15
FI791565A (fi) 1979-11-18
IL57298A (en) 1983-09-30
CA1141661A (en) 1983-02-22
CS214798B2 (en) 1982-05-28
EP0005768A1 (en) 1979-12-12
SE450930B (sv) 1987-08-17
IT1116840B (it) 1986-02-10
DK156004C (da) 1989-11-06
PL215627A1 (xx) 1981-08-07
AT365926B (de) 1982-02-25
DE2920020C2 (xx) 1988-09-01
NZ190462A (en) 1982-05-31
BE876296A (fr) 1979-11-16
FI68359B (fi) 1985-05-31
KR830000527B1 (ko) 1983-03-12
NL7903871A (nl) 1979-11-20
JPS54163809A (en) 1979-12-26
ATA363479A (de) 1981-07-15
ES480597A1 (es) 1980-08-16
DK156004B (da) 1989-06-12
LU81272A1 (fr) 1979-12-07
HU182746B (en) 1984-03-28
IL57298A0 (en) 1979-09-30
GR68452B (xx) 1981-12-30
MC1265A1 (fr) 1980-03-28
AU525695B2 (en) 1982-11-25
ATE4411T1 (de) 1983-08-15
DE2920020A1 (de) 1979-11-29
PL134004B1 (en) 1985-07-31
FR2425856B1 (xx) 1982-06-25
CH641044A5 (de) 1984-02-15
EP0005768B1 (en) 1983-08-10
JPS6358810B2 (xx) 1988-11-17
ZA787353B (en) 1980-08-27
IT7949064A0 (it) 1979-05-16
DK201879A (da) 1979-11-18
FR2425856A1 (fr) 1979-12-14
SE7904284L (sv) 1979-11-18
PH15850A (en) 1983-04-13

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MA Patent expired

Owner name: THE WELLCOME FOUNDATION LIMITED