FI66389C - Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar - Google Patents

Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar Download PDF

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Publication number
FI66389C
FI66389C FI750503A FI750503A FI66389C FI 66389 C FI66389 C FI 66389C FI 750503 A FI750503 A FI 750503A FI 750503 A FI750503 A FI 750503A FI 66389 C FI66389 C FI 66389C
Authority
FI
Finland
Prior art keywords
acid
group
phenoxyacetamido
formula
cephem
Prior art date
Application number
FI750503A
Other languages
English (en)
Finnish (fi)
Other versions
FI750503A (da
FI66389B (fi
Inventor
Robert Burns Woodward
Hans Bickel
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH269374A external-priority patent/CH601310A5/de
Priority claimed from CH776674A external-priority patent/CH610584A5/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI750503A publication Critical patent/FI750503A/fi
Application granted granted Critical
Publication of FI66389B publication Critical patent/FI66389B/fi
Publication of FI66389C publication Critical patent/FI66389C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02—Sulfinic acids; Derivatives thereof
    • C07C313/04—Sulfinic acids; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI750503A 1974-02-26 1975-02-21 Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar FI66389C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH269374 1974-02-26
CH269374A CH601310A5 (en) 1974-02-26 1974-02-26 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CH776674 1974-06-05
CH776674A CH610584A5 (en) 1974-02-26 1974-06-05 Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
CH1100074 1974-08-12
CH1100074 1974-08-12

Publications (3)

Publication Number Publication Date
FI750503A FI750503A (da) 1975-08-27
FI66389B FI66389B (fi) 1984-06-29
FI66389C true FI66389C (fi) 1984-10-10

Family

ID=27173851

Family Applications (1)

Application Number Title Priority Date Filing Date
FI750503A FI66389C (fi) 1974-02-26 1975-02-21 Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar

Country Status (21)

Country Link
JP (1) JPS625919B2 (da)
AR (1) AR208538A1 (da)
AT (2) AT337362B (da)
AU (1) AU498131B2 (da)
BE (1) BE825919A (da)
BG (1) BG26201A3 (da)
CA (2) CA1059988A (da)
DD (1) DD117074A5 (da)
DE (1) DE2506330A1 (da)
DK (2) DK73475A (da)
ES (2) ES435110A1 (da)
FI (1) FI66389C (da)
FR (1) FR2261761B1 (da)
GB (1) GB1503581A (da)
HU (1) HU175212B (da)
IE (1) IE40695B1 (da)
IL (1) IL46699A (da)
NL (1) NL7502292A (da)
NO (1) NO750625L (da)
NZ (1) NZ176623A (da)
SE (3) SE431652B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044247B (it) * 1974-08-02 1980-03-20 Farmaceutici Italia Intermedi per la sintesi di derivati b lattamici e procedimento per la loro preparazone
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
JPS5198265A (da) * 1975-02-17 1976-08-30
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4029645A (en) * 1975-11-17 1977-06-14 E. R. Squibb & Sons, Inc. Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins
JPH0639474B2 (ja) * 1983-03-04 1994-05-25 大塚化学株式会社 セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井　康博 薬液収納兼即効注出器
JPS60126263A (ja) * 1983-12-12 1985-07-05 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60237061A (ja) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
GB2152497B (en) * 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
JPS60115562A (ja) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3195959B2 (ja) * 1991-03-13 2001-08-06 大塚化学株式会社 ３−ヒドロキシセフェム誘導体の製造法
KR20050087791A (ko) * 2002-11-01 2005-08-31 오키드 케미칼즈 앤드 파마수티컬즈 리미티드 클로로메틸 세펨 유도체 제조를 위한 개선된 제조방법
US9708357B2 (en) 2011-12-20 2017-07-18 Riboscience, LLC 4′-azido, 3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication
ES2636448T3 (es) 2011-12-20 2017-10-05 Riboscience Llc Derivados de nucleósido 2',4'-difluoro-2'-metil sustituidos como inhibidores de la replicación del ARN del VHC
PE20160119A1 (es) 2013-05-16 2016-02-24 Riboscience Llc Derivados de nucleosido 4'-azido, 3'-desoxi-3'-fluoro sustituido
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
WO2014186637A1 (en) 2013-05-16 2014-11-20 Riboscience Llc 4'-fluor0-2'-methyl substituted nucleoside derivatives
JP7299897B2 (ja) 2017-09-21 2023-06-28 リボサイエンス リミティド ライアビリティ カンパニー Ｈｃｖのｒｎａ複製阻害剤としての４’－フルオロ－２’－メチル置換ヌクレオシド誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230372A1 (de) * 1972-06-21 1973-01-11 Fujisawa Pharmaceutical Co Verfahren zur herstellung von oxidierten penam-derivaten
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat

Also Published As

Publication number Publication date
JPS625919B2 (da) 1987-02-07
SE438855B (sv) 1985-05-13
SE7501317L (da) 1975-08-27
CA1080713A (en) 1980-07-01
SE7807811L (sv) 1978-07-13
CA1059988A (en) 1979-08-07
FI750503A (da) 1975-08-27
ATA28178A (de) 1978-10-15
ATA108275A (de) 1976-10-15
AU7849875A (en) 1976-08-26
NL7502292A (nl) 1975-08-28
FR2261761B1 (da) 1978-08-18
AT337362B (de) 1977-06-27
GB1503581A (en) 1978-03-15
SE7807810L (sv) 1978-07-13
IE40695B1 (en) 1979-08-01
IL46699A0 (en) 1975-04-25
HU175212B (hu) 1980-06-28
AR208538A1 (es) 1977-02-15
FI66389B (fi) 1984-06-29
FR2261761A1 (da) 1975-09-19
DK73475A (da) 1975-10-20
BE825919A (fr) 1975-08-25
JPS50129590A (da) 1975-10-13
DK348678A (da) 1978-08-07
ES452915A1 (es) 1977-11-01
BG26201A3 (da) 1979-02-15
SE431652B (sv) 1984-02-20
AU498131B2 (en) 1979-02-15
NZ176623A (en) 1978-04-03
ES435110A1 (es) 1977-03-16
IL46699A (en) 1977-11-30
SE438854B (sv) 1985-05-13
AT350068B (de) 1979-05-10
NO750625L (da) 1975-08-27
IE40695L (en) 1975-08-26
DE2506330A1 (de) 1975-09-04
DD117074A5 (da) 1975-12-20

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MM Patent lapsed

Owner name: CIBA-GEIGY AG