FI66389C - Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar - Google Patents

Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar Download PDF

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Publication number
FI66389C
FI66389C FI750503A FI750503A FI66389C FI 66389 C FI66389 C FI 66389C FI 750503 A FI750503 A FI 750503A FI 750503 A FI750503 A FI 750503A FI 66389 C FI66389 C FI 66389C
Authority
FI
Finland
Prior art keywords
acid
group
phenoxyacetamido
formula
cephem
Prior art date
Application number
FI750503A
Other languages
English (en)
Finnish (fi)
Other versions
FI66389B (fi
FI750503A (US06331856-20011218-P00035.png
Inventor
Robert Burns Woodward
Hans Bickel
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH269374A external-priority patent/CH601310A5/de
Priority claimed from CH776674A external-priority patent/CH610584A5/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI750503A publication Critical patent/FI750503A/fi
Publication of FI66389B publication Critical patent/FI66389B/fi
Application granted granted Critical
Publication of FI66389C publication Critical patent/FI66389C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02Sulfinic acids; Derivatives thereof
    • C07C313/04Sulfinic acids; Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI750503A 1974-02-26 1975-02-21 Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar FI66389C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH269374A CH601310A5 (en) 1974-02-26 1974-02-26 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CH269374 1974-02-26
CH776674A CH610584A5 (en) 1974-02-26 1974-06-05 Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
CH776674 1974-06-05
CH1100074 1974-08-12
CH1100074 1974-08-12

Publications (3)

Publication Number Publication Date
FI750503A FI750503A (US06331856-20011218-P00035.png) 1975-08-27
FI66389B FI66389B (fi) 1984-06-29
FI66389C true FI66389C (fi) 1984-10-10

Family

ID=27173851

Family Applications (1)

Application Number Title Priority Date Filing Date
FI750503A FI66389C (fi) 1974-02-26 1975-02-21 Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar

Country Status (21)

Country Link
JP (1) JPS625919B2 (US06331856-20011218-P00035.png)
AR (1) AR208538A1 (US06331856-20011218-P00035.png)
AT (2) AT337362B (US06331856-20011218-P00035.png)
AU (1) AU498131B2 (US06331856-20011218-P00035.png)
BE (1) BE825919A (US06331856-20011218-P00035.png)
BG (1) BG26201A3 (US06331856-20011218-P00035.png)
CA (2) CA1059988A (US06331856-20011218-P00035.png)
DD (1) DD117074A5 (US06331856-20011218-P00035.png)
DE (1) DE2506330A1 (US06331856-20011218-P00035.png)
DK (2) DK73475A (US06331856-20011218-P00035.png)
ES (2) ES435110A1 (US06331856-20011218-P00035.png)
FI (1) FI66389C (US06331856-20011218-P00035.png)
FR (1) FR2261761B1 (US06331856-20011218-P00035.png)
GB (1) GB1503581A (US06331856-20011218-P00035.png)
HU (1) HU175212B (US06331856-20011218-P00035.png)
IE (1) IE40695B1 (US06331856-20011218-P00035.png)
IL (1) IL46699A (US06331856-20011218-P00035.png)
NL (1) NL7502292A (US06331856-20011218-P00035.png)
NO (1) NO750625L (US06331856-20011218-P00035.png)
NZ (1) NZ176623A (US06331856-20011218-P00035.png)
SE (3) SE431652B (US06331856-20011218-P00035.png)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044247B (it) * 1974-08-02 1980-03-20 Farmaceutici Italia Intermedi per la sintesi di derivati b lattamici e procedimento per la loro preparazone
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
JPS5198265A (US06331856-20011218-P00035.png) * 1975-02-17 1976-08-30
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4029645A (en) * 1975-11-17 1977-06-14 E. R. Squibb & Sons, Inc. Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins
JPH0639474B2 (ja) * 1983-03-04 1994-05-25 大塚化学株式会社 セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井 康博 薬液収納兼即効注出器
JPS60115562A (ja) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60237061A (ja) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60126263A (ja) * 1983-12-12 1985-07-05 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
GB2152497B (en) * 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3195959B2 (ja) * 1991-03-13 2001-08-06 大塚化学株式会社 3−ヒドロキシセフェム誘導体の製造法
JP2006507289A (ja) * 2002-11-01 2006-03-02 オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド 改良されたクロロメチルセフェム誘導体調製方法
MX350810B (es) 2011-12-20 2017-09-20 Riboscience Llc Derivados de los nucleosidos sustituidos en 4 '-azido, 3 '-fluoro como inhibidores de la replicacion del rna del vhc.
CN104011061B (zh) 2011-12-20 2017-06-13 里博科学有限责任公司 作为hcv rna复制抑制剂的2‘,4’‑二氟‑2‘‑甲基取代的核苷衍生物
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
CN105307661A (zh) 2013-05-16 2016-02-03 里博科学有限责任公司 4’-叠氮基,3’-脱氧基-3’-氟取代的核苷衍生物
KR102241198B1 (ko) 2013-05-16 2021-04-15 리보사이언스 엘엘씨 4'-플루오로-2'-메틸 치환된 뉴클레오시드 유도체
US10682369B2 (en) 2017-09-21 2020-06-16 Riboscience Llc 4′-fluoro-2′-methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230372A1 (de) * 1972-06-21 1973-01-11 Fujisawa Pharmaceutical Co Verfahren zur herstellung von oxidierten penam-derivaten
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat

Also Published As

Publication number Publication date
SE438854B (sv) 1985-05-13
FR2261761A1 (US06331856-20011218-P00035.png) 1975-09-19
IE40695B1 (en) 1979-08-01
SE431652B (sv) 1984-02-20
CA1080713A (en) 1980-07-01
JPS625919B2 (US06331856-20011218-P00035.png) 1987-02-07
AU498131B2 (en) 1979-02-15
AT337362B (de) 1977-06-27
IL46699A (en) 1977-11-30
FI66389B (fi) 1984-06-29
ATA108275A (de) 1976-10-15
DK73475A (US06331856-20011218-P00035.png) 1975-10-20
FI750503A (US06331856-20011218-P00035.png) 1975-08-27
CA1059988A (en) 1979-08-07
BG26201A3 (US06331856-20011218-P00035.png) 1979-02-15
ATA28178A (de) 1978-10-15
AU7849875A (en) 1976-08-26
IE40695L (en) 1975-08-26
SE7807811L (sv) 1978-07-13
IL46699A0 (en) 1975-04-25
SE7807810L (sv) 1978-07-13
DK348678A (da) 1978-08-07
NZ176623A (en) 1978-04-03
ES452915A1 (es) 1977-11-01
DD117074A5 (US06331856-20011218-P00035.png) 1975-12-20
JPS50129590A (US06331856-20011218-P00035.png) 1975-10-13
ES435110A1 (es) 1977-03-16
BE825919A (fr) 1975-08-25
SE438855B (sv) 1985-05-13
DE2506330A1 (de) 1975-09-04
AT350068B (de) 1979-05-10
FR2261761B1 (US06331856-20011218-P00035.png) 1978-08-18
SE7501317L (US06331856-20011218-P00035.png) 1975-08-27
NO750625L (US06331856-20011218-P00035.png) 1975-08-27
HU175212B (hu) 1980-06-28
AR208538A1 (es) 1977-02-15
NL7502292A (nl) 1975-08-28
GB1503581A (en) 1978-03-15

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Owner name: CIBA-GEIGY AG