FI66385C - Foerfarande foer framstaellning av terapeutiskt anvaendbara spro(imidazolidin-4,4'-(4'h)-naftopyran-(och naftotiopyran) -25-dion-derivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara spro(imidazolidin-4,4'-(4'h)-naftopyran-(och naftotiopyran) -25-dion-derivat Download PDF

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Publication number
FI66385C
FI66385C FI793586A FI793586A FI66385C FI 66385 C FI66385 C FI 66385C FI 793586 A FI793586 A FI 793586A FI 793586 A FI793586 A FI 793586A FI 66385 C FI66385 C FI 66385C
Authority
FI
Finland
Prior art keywords
imidazolidine
spiro
derivatives
och
naphthotiopyran
Prior art date
Application number
FI793586A
Other languages
English (en)
Finnish (fi)
Other versions
FI66385B (fi
FI793586A (fi
Inventor
Reinhard Sarges
John Belletire
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI793586A publication Critical patent/FI793586A/fi
Priority to FI832042A priority Critical patent/FI77235C/fi
Publication of FI66385B publication Critical patent/FI66385B/fi
Application granted granted Critical
Publication of FI66385C publication Critical patent/FI66385C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI793586A 1978-11-16 1979-11-15 Foerfarande foer framstaellning av terapeutiskt anvaendbara spro(imidazolidin-4,4'-(4'h)-naftopyran-(och naftotiopyran) -25-dion-derivat FI66385C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI832042A FI77235C (fi) 1978-11-16 1983-06-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara spiro-polycykliska imidazolidindionderivat.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/961,335 US4181728A (en) 1978-11-16 1978-11-16 Spiro-polycyclicimidazolidinedione derivatives
US96133578 1978-11-16

Publications (3)

Publication Number Publication Date
FI793586A FI793586A (fi) 1980-05-17
FI66385B FI66385B (fi) 1984-06-29
FI66385C true FI66385C (fi) 1984-10-10

Family

ID=25504341

Family Applications (1)

Application Number Title Priority Date Filing Date
FI793586A FI66385C (fi) 1978-11-16 1979-11-15 Foerfarande foer framstaellning av terapeutiskt anvaendbara spro(imidazolidin-4,4'-(4'h)-naftopyran-(och naftotiopyran) -25-dion-derivat

Country Status (23)

Country Link
US (1) US4181728A (de)
JP (2) JPS6052157B2 (de)
AR (1) AR222052A1 (de)
AT (1) AT369742B (de)
AU (1) AU515301B2 (de)
BE (1) BE880065A (de)
CA (1) CA1125294A (de)
CH (1) CH642358A5 (de)
DE (1) DE2946037A1 (de)
DK (1) DK484479A (de)
ES (1) ES486007A1 (de)
FI (1) FI66385C (de)
FR (1) FR2441627A1 (de)
GB (1) GB2038315B (de)
IE (1) IE49116B1 (de)
IL (1) IL58730A (de)
IT (1) IT1127231B (de)
LU (1) LU81890A1 (de)
NL (1) NL177689C (de)
PH (1) PH15672A (de)
PT (1) PT70452A (de)
SE (1) SE447731B (de)
YU (1) YU41678B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU532110B2 (en) * 1979-11-13 1983-09-15 Ici Ltd. Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives
ATE10940T1 (de) * 1981-05-12 1985-01-15 Imperial Chemical Industries Plc Pyrrolderivate.
US4436745A (en) 1982-04-15 1984-03-13 Alcon Laboratories, Inc. Method of inhibiting aldose reductase activity
US4540700A (en) * 1982-04-15 1985-09-10 Alcon Laboratories, Inc. Treatment of diabetic complications with certain spiro-imidazolidine-diones
US4464385A (en) * 1982-04-15 1984-08-07 Alcon Laboratories, Inc. Treatment of diabetic complications with hydantoins
US4438272A (en) 1982-04-15 1984-03-20 Alcon Laboratories, Inc. Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
IL68314A0 (en) * 1982-04-15 1983-07-31 Alcon Lab Inc Method and composition for inhibiting aldose reductase activity and process for preparing spirofluorofluoren and spiro-difluorofluoren compounds
JPS59500618A (ja) * 1982-04-15 1984-04-12 アルコン・ラボラトリ−ズ・インコ−ポレ−テッド スピロ―フルオロフルオレン化合物、その製造法およびアルド―スレダクターゼ活性を阻害する組成物
DE3342933A1 (de) * 1983-11-26 1985-06-05 Horst G. 5190 Stolberg Schumann Regalfoerderzeug
US4717725A (en) * 1984-04-11 1988-01-05 Alcon Laboratories, Inc. Ophthalmic wound healing with aldose reductase inhibitors
US4600717A (en) * 1984-04-11 1986-07-15 Alcon Laboratories, Inc. Aldose reductase inhibitors useful in ophthalmic wound healing
US4609663A (en) * 1984-09-11 1986-09-02 Alcon Laboratories, Inc. Aldose reductase inhibitors useful in glaucoma therapy
US4576143A (en) * 1984-10-05 1986-03-18 Clark Iii William T Method of immune modification by means of extracorporeal irradiation of the blood
US5340829A (en) * 1984-11-20 1994-08-23 Washington Research Foundation Immunoregulatory agents
US4966911A (en) * 1984-11-20 1990-10-30 Washington Research Foundation Immunoregulatory agents
JPS6372140U (de) * 1986-10-29 1988-05-14
JPS63119451U (de) * 1987-01-30 1988-08-02
WO1992000071A1 (en) * 1989-02-10 1992-01-09 Washington Research Foundation Immunoregulatory agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683718A (en) * 1952-01-11 1954-07-13 Searle & Co Spiro-[xanthene-9, 4'-imidazolidine]-2, 5-dione
DE1032257B (de) * 1954-05-27 1958-06-19 Cutter Lab Verfahren zur Herstellung neuer Hydantoine
GB796069A (en) * 1955-12-23 1958-06-04 Ici Ltd Substituted hydantoins
GB818724A (en) * 1956-10-18 1959-08-19 Ici Ltd Hydantoin derivatives
US3532744A (en) * 1967-07-28 1970-10-06 American Home Prod 1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4078064A (en) * 1976-08-18 1978-03-07 E. R. Squibb & Sons, Inc. 8H-Pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidines
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4127665A (en) * 1978-01-18 1978-11-28 Pfizer Inc. Thienohydantoin derivatives

Also Published As

Publication number Publication date
JPS6144868B2 (de) 1986-10-04
FI66385B (fi) 1984-06-29
FI793586A (fi) 1980-05-17
NL177689C (nl) 1985-11-01
PT70452A (en) 1979-12-01
CH642358A5 (fr) 1984-04-13
SE447731B (sv) 1986-12-08
ATA729779A (de) 1982-06-15
CA1125294A (en) 1982-06-08
FR2441627B1 (de) 1983-06-03
PH15672A (en) 1983-03-11
LU81890A1 (fr) 1980-06-05
US4181728A (en) 1980-01-01
YU277379A (en) 1983-01-21
IE792184L (en) 1980-05-16
AR222052A1 (es) 1981-04-15
AU5288079A (en) 1980-05-22
FR2441627A1 (fr) 1980-06-13
ES486007A1 (es) 1980-09-01
YU41678B (en) 1987-12-31
DK484479A (da) 1980-05-17
IL58730A0 (en) 1980-02-29
IT7927311A0 (it) 1979-11-15
NL7908352A (nl) 1980-05-20
IL58730A (en) 1984-01-31
BE880065A (fr) 1980-05-16
AU515301B2 (en) 1981-03-26
IT1127231B (it) 1986-05-21
NL177689B (nl) 1985-06-03
DE2946037A1 (de) 1980-05-22
GB2038315B (en) 1982-08-11
JPS60120870A (ja) 1985-06-28
GB2038315A (en) 1980-07-23
JPS5589268A (en) 1980-07-05
IE49116B1 (en) 1985-08-07
JPS6052157B2 (ja) 1985-11-18
SE7909439L (sv) 1980-05-17
AT369742B (de) 1983-01-25

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Owner name: PFIZER INC.