FI61482C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara n-aryl-n-(1-l-4-piperidinyl)-arylacetamider - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara n-aryl-n-(1-l-4-piperidinyl)-arylacetamider Download PDF

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Publication number
FI61482C
FI61482C FI762698A FI762698A FI61482C FI 61482 C FI61482 C FI 61482C FI 762698 A FI762698 A FI 762698A FI 762698 A FI762698 A FI 762698A FI 61482 C FI61482 C FI 61482C
Authority
FI
Finland
Prior art keywords
parts
piperidinyl
phenyl
formula
compound
Prior art date
Application number
FI762698A
Other languages
English (en)
Finnish (fi)
Other versions
FI762698A (el
FI61482B (fi
Inventor
Stefan Sanczuk
Hubert K Fr Hermans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI762698A publication Critical patent/FI762698A/fi
Application granted granted Critical
Publication of FI61482B publication Critical patent/FI61482B/fi
Publication of FI61482C publication Critical patent/FI61482C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI762698A 1975-09-23 1976-09-22 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara n-aryl-n-(1-l-4-piperidinyl)-arylacetamider FI61482C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61513175A 1975-09-23 1975-09-23
US61513175 1975-09-23
US71375676A 1976-08-12 1976-08-12
US71375676 1976-08-12

Publications (3)

Publication Number Publication Date
FI762698A FI762698A (el) 1977-03-24
FI61482B FI61482B (fi) 1982-04-30
FI61482C true FI61482C (fi) 1982-08-10

Family

ID=27087421

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762698A FI61482C (fi) 1975-09-23 1976-09-22 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara n-aryl-n-(1-l-4-piperidinyl)-arylacetamider

Country Status (29)

Country Link
JP (1) JPS6016417B2 (el)
AT (1) AT363935B (el)
AU (1) AU510029B2 (el)
BG (1) BG27543A3 (el)
CA (1) CA1068271A (el)
CH (1) CH628623A5 (el)
CS (1) CS222663B2 (el)
DE (1) DE2642856A1 (el)
DK (1) DK150478C (el)
ES (1) ES451768A1 (el)
FI (1) FI61482C (el)
FR (1) FR2325377A1 (el)
GB (1) GB1539473A (el)
GR (1) GR58469B (el)
HU (1) HU172964B (el)
IE (1) IE43802B1 (el)
IL (1) IL50522A (el)
IT (1) IT1073893B (el)
LU (1) LU75837A1 (el)
NL (1) NL187267C (el)
NO (1) NO147672C (el)
NZ (1) NZ181972A (el)
PH (1) PH12497A (el)
PL (2) PL192578A1 (el)
PT (1) PT65631B (el)
RO (1) RO70079A (el)
SE (1) SE427839B (el)
SU (1) SU747424A3 (el)
YU (1) YU39973B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA765684B (en) * 1975-09-23 1978-04-26 Janssen Pharmaceutica Nv Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
JPS62260786A (ja) * 1986-05-08 1987-11-13 株式会社ヘキトク 燻瓦の製造ラインにおける焼成工程後の表面仕上げ装置
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JP2010525013A (ja) * 2007-04-23 2010-07-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 高速解離性ドパミン２受容体アンタゴニストとしてのピリジン誘導体
JP5431305B2 (ja) 2007-04-23 2014-03-05 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 高速解離性ドパミン２受容体アンタゴニストとしての４−アルコキシピリダジン誘導体
AU2008240729B2 (en) 2007-04-23 2012-08-23 Janssen Pharmaceutica N.V. Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists
CA2729313C (en) 2008-07-03 2016-08-30 Janssen Pharmaceutica Nv Substituted 6-(1-piperazinyl)-pyridazines as 5-ht6 receptor antagonists
DK2307374T3 (en) 2008-07-31 2017-05-01 Janssen Pharmaceutica Nv PIPERAZIN-1-YLTRIFLUORMETHYL-SUBSTITUTED PYRIDINES AS QUICK DISSOCATING DOPAMIN-2 RECEPTOR ANTAGONISTS

Also Published As

Publication number Publication date
BG27543A3 (en) 1979-11-12
CA1068271A (en) 1979-12-18
LU75837A1 (el) 1977-05-04
NO147672C (no) 1983-05-25
YU233676A (en) 1983-01-21
NO763054L (no) 1977-03-24
DE2642856C2 (el) 1990-06-21
DK427876A (da) 1977-03-24
AU510029B2 (en) 1980-06-05
SE427839B (sv) 1983-05-09
SU747424A3 (ru) 1980-07-23
AU1787876A (en) 1978-03-23
YU39973B (en) 1985-06-30
FR2325377A1 (fr) 1977-04-22
DK150478B (da) 1987-03-09
NO147672B (no) 1983-02-14
JPS5239683A (en) 1977-03-28
RO70079A (ro) 1982-10-26
PT65631A (en) 1976-10-01
DE2642856A1 (de) 1977-03-24
IE43802B1 (en) 1981-06-03
PT65631B (en) 1978-07-05
SE7610501L (sv) 1977-03-24
NL7610513A (nl) 1977-03-25
AT363935B (de) 1981-09-10
NL187267B (nl) 1991-03-01
GB1539473A (en) 1979-01-31
DK150478C (da) 1987-10-05
CH628623A5 (en) 1982-03-15
ATA702976A (de) 1981-02-15
IE43802L (en) 1977-03-23
CS222663B2 (en) 1983-07-29
JPS6016417B2 (ja) 1985-04-25
PL192578A1 (pl) 1979-02-26
IT1073893B (it) 1985-04-17
FI762698A (el) 1977-03-24
IL50522A (en) 1979-09-30
IL50522A0 (en) 1976-11-30
GR58469B (en) 1977-10-14
PH12497A (en) 1979-04-05
PL117323B1 (en) 1981-07-31
ES451768A1 (es) 1978-05-01
NL187267C (nl) 1991-08-01
NZ181972A (en) 1978-07-28
FR2325377B1 (el) 1980-04-18
HU172964B (hu) 1979-01-28
FI61482B (fi) 1982-04-30

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Date Code Title Description
MM Patent lapsed

Owner name: JANSSEN PHARMACEUTICA N.V.