IE43802L - N-aryl-n-(4-piperidinyl) arylacetamide derivatives. - Google Patents

N-aryl-n-(4-piperidinyl) arylacetamide derivatives.

Info

Publication number
IE43802L
IE43802L IE762095A IE209576A IE43802L IE 43802 L IE43802 L IE 43802L IE 762095 A IE762095 A IE 762095A IE 209576 A IE209576 A IE 209576A IE 43802 L IE43802 L IE 43802L
Authority
IE
Ireland
Prior art keywords
piperidinyl
aryl
derivatives
formula
arylacetamide
Prior art date
Application number
IE762095A
Other versions
IE43802B1 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IE43802L publication Critical patent/IE43802L/en
Publication of IE43802B1 publication Critical patent/IE43802B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Abstract

N-Aryl-N-(4-piperidinyl)arylacetamides of the formula <IMAGE> and their salts with acids, the substituents in the formula being defined in Claim 1, are prepared. These compounds are obtained by acylating corresponding piperidine derivatives with an arylacetyl halide. The resulting compounds can be used for the drug therapy of cardiac arrhythmias. [GB1539473A]
IE2095/76A 1975-09-23 1976-09-22 Novel-n-aryl-n-(1-l-4-piperidinyl)-arylacetamides IE43802B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61513175A 1975-09-23 1975-09-23
US71375676A 1976-08-12 1976-08-12

Publications (2)

Publication Number Publication Date
IE43802L true IE43802L (en) 1977-03-23
IE43802B1 IE43802B1 (en) 1981-06-03

Family

ID=27087421

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2095/76A IE43802B1 (en) 1975-09-23 1976-09-22 Novel-n-aryl-n-(1-l-4-piperidinyl)-arylacetamides

Country Status (29)

Country Link
JP (1) JPS6016417B2 (en)
AT (1) AT363935B (en)
AU (1) AU510029B2 (en)
BG (1) BG27543A3 (en)
CA (1) CA1068271A (en)
CH (1) CH628623A5 (en)
CS (1) CS222663B2 (en)
DE (1) DE2642856A1 (en)
DK (1) DK150478C (en)
ES (1) ES451768A1 (en)
FI (1) FI61482C (en)
FR (1) FR2325377A1 (en)
GB (1) GB1539473A (en)
GR (1) GR58469B (en)
HU (1) HU172964B (en)
IE (1) IE43802B1 (en)
IL (1) IL50522A (en)
IT (1) IT1073893B (en)
LU (1) LU75837A1 (en)
NL (1) NL187267C (en)
NO (1) NO147672C (en)
NZ (1) NZ181972A (en)
PH (1) PH12497A (en)
PL (2) PL117323B1 (en)
PT (1) PT65631B (en)
RO (1) RO70079A (en)
SE (1) SE427839B (en)
SU (1) SU747424A3 (en)
YU (1) YU39973B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA765684B (en) * 1975-09-23 1978-04-26 Janssen Pharmaceutica Nv Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
JPS62260786A (en) * 1986-05-08 1987-11-13 株式会社ヘキトク Line system for manufacturing smoked roof tile
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Fast Dissociting Dopamine 2 Receptor Antagonists
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Fast Dissociating Dopamine 2 Receptor Antagonists
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Fast -Dissociating Dopamine 2 Receptor Antagonists
ES2400710T3 (en) 2007-04-23 2013-04-11 Janssen Pharmaceutica, N.V. Tia (dia) zoles as fast dissociation dopamine 2 receptor antagonists
JP2010525013A (en) * 2007-04-23 2010-07-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists
US8906921B2 (en) 2007-04-23 2014-12-09 Janssen Pharmaceutica Nv 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists
WO2010000456A1 (en) 2008-07-03 2010-01-07 Janssen Pharmaceutica Nv Substituted 6- (1-piperazinyl) -pyridazines as 5-ht6 receptor antagonists
EA019048B1 (en) 2008-07-31 2013-12-30 Янссен Фармацевтика Нв Piperazin-1-yl-trifluoromethyl-substituted pyridines as fast dissociating dopamine 2 receptor antagonists

Also Published As

Publication number Publication date
BG27543A3 (en) 1979-11-12
AU1787876A (en) 1978-03-23
PH12497A (en) 1979-04-05
ES451768A1 (en) 1978-05-01
NO147672C (en) 1983-05-25
GB1539473A (en) 1979-01-31
IE43802B1 (en) 1981-06-03
RO70079A (en) 1982-10-26
FR2325377A1 (en) 1977-04-22
CA1068271A (en) 1979-12-18
PL192578A1 (en) 1979-02-26
DE2642856C2 (en) 1990-06-21
DK150478C (en) 1987-10-05
PT65631A (en) 1976-10-01
GR58469B (en) 1977-10-14
DK427876A (en) 1977-03-24
NZ181972A (en) 1978-07-28
JPS5239683A (en) 1977-03-28
IL50522A0 (en) 1976-11-30
DE2642856A1 (en) 1977-03-24
FI61482B (en) 1982-04-30
NO763054L (en) 1977-03-24
NO147672B (en) 1983-02-14
AT363935B (en) 1981-09-10
NL187267B (en) 1991-03-01
IL50522A (en) 1979-09-30
YU39973B (en) 1985-06-30
ATA702976A (en) 1981-02-15
NL187267C (en) 1991-08-01
LU75837A1 (en) 1977-05-04
SE7610501L (en) 1977-03-24
SU747424A3 (en) 1980-07-23
PL117323B1 (en) 1981-07-31
SE427839B (en) 1983-05-09
HU172964B (en) 1979-01-28
PT65631B (en) 1978-07-05
CS222663B2 (en) 1983-07-29
CH628623A5 (en) 1982-03-15
YU233676A (en) 1983-01-21
IT1073893B (en) 1985-04-17
NL7610513A (en) 1977-03-25
FR2325377B1 (en) 1980-04-18
AU510029B2 (en) 1980-06-05
JPS6016417B2 (en) 1985-04-25
FI61482C (en) 1982-08-10
DK150478B (en) 1987-03-09
FI762698A (en) 1977-03-24

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