ES451768A1 - N-aryl-n-(1-l-4-piperidinyl)-arylacetamides - Google Patents
N-aryl-n-(1-l-4-piperidinyl)-arylacetamidesInfo
- Publication number
- ES451768A1 ES451768A1 ES451768A ES451768A ES451768A1 ES 451768 A1 ES451768 A1 ES 451768A1 ES 451768 A ES451768 A ES 451768A ES 451768 A ES451768 A ES 451768A ES 451768 A1 ES451768 A1 ES 451768A1
- Authority
- ES
- Spain
- Prior art keywords
- arylacetamides
- piperidinyl
- aryl
- formula
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
Abstract
N-Aryl-N-(4-piperidinyl)arylacetamides of the formula < IMAGE > and their salts with acids, the substituents in the formula being defined in Claim 1, are prepared. These compounds are obtained by acylating corresponding piperidine derivatives with an arylacetyl halide. The resulting compounds can be used for the drug therapy of cardiac arrhythmias.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61513175A | 1975-09-23 | 1975-09-23 | |
| US71375676A | 1976-08-12 | 1976-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES451768A1 true ES451768A1 (en) | 1978-05-01 |
Family
ID=27087421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES451768A Expired ES451768A1 (en) | 1975-09-23 | 1976-09-22 | N-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS6016417B2 (en) |
| AT (1) | AT363935B (en) |
| AU (1) | AU510029B2 (en) |
| BG (1) | BG27543A3 (en) |
| CA (1) | CA1068271A (en) |
| CH (1) | CH628623A5 (en) |
| CS (1) | CS222663B2 (en) |
| DE (1) | DE2642856A1 (en) |
| DK (1) | DK150478C (en) |
| ES (1) | ES451768A1 (en) |
| FI (1) | FI61482C (en) |
| FR (1) | FR2325377A1 (en) |
| GB (1) | GB1539473A (en) |
| GR (1) | GR58469B (en) |
| HU (1) | HU172964B (en) |
| IE (1) | IE43802B1 (en) |
| IL (1) | IL50522A (en) |
| IT (1) | IT1073893B (en) |
| LU (1) | LU75837A1 (en) |
| NL (1) | NL187267C (en) |
| NO (1) | NO147672C (en) |
| NZ (1) | NZ181972A (en) |
| PH (1) | PH12497A (en) |
| PL (2) | PL117323B1 (en) |
| PT (1) | PT65631B (en) |
| RO (1) | RO70079A (en) |
| SE (1) | SE427839B (en) |
| SU (1) | SU747424A3 (en) |
| YU (1) | YU39973B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA765684B (en) * | 1975-09-23 | 1978-04-26 | Janssen Pharmaceutica Nv | Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| JPS62260786A (en) * | 1986-05-08 | 1987-11-13 | 株式会社ヘキトク | Line system for manufacturing smoked roof tile |
| JO2769B1 (en) | 2005-10-26 | 2014-03-15 | جانسين فارماسوتيكا ان. في | Fast Dissociting Dopamine 2 Receptor Antagonists |
| JO2642B1 (en) | 2006-12-08 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Fast Dissociating Dopamine 2 Receptor Antagonists |
| JO2849B1 (en) | 2007-02-13 | 2015-03-15 | جانسين فارماسوتيكا ان. في | Fast -Dissociating Dopamine 2 Receptor Antagonists |
| ES2400710T3 (en) | 2007-04-23 | 2013-04-11 | Janssen Pharmaceutica, N.V. | Tia (dia) zoles as fast dissociation dopamine 2 receptor antagonists |
| JP2010525013A (en) * | 2007-04-23 | 2010-07-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists |
| US8906921B2 (en) | 2007-04-23 | 2014-12-09 | Janssen Pharmaceutica Nv | 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists |
| WO2010000456A1 (en) | 2008-07-03 | 2010-01-07 | Janssen Pharmaceutica Nv | Substituted 6- (1-piperazinyl) -pyridazines as 5-ht6 receptor antagonists |
| EA019048B1 (en) | 2008-07-31 | 2013-12-30 | Янссен Фармацевтика Нв | Piperazin-1-yl-trifluoromethyl-substituted pyridines as fast dissociating dopamine 2 receptor antagonists |
-
1976
- 1976-09-06 NO NO763054A patent/NO147672C/en unknown
- 1976-09-08 NZ NZ181972A patent/NZ181972A/en unknown
- 1976-09-16 FR FR7627870A patent/FR2325377A1/en active Granted
- 1976-09-17 AU AU17878/76A patent/AU510029B2/en not_active Expired
- 1976-09-20 LU LU75837A patent/LU75837A1/xx unknown
- 1976-09-20 RO RO7687590A patent/RO70079A/en unknown
- 1976-09-20 CA CA261,551A patent/CA1068271A/en not_active Expired
- 1976-09-21 CH CH1194876A patent/CH628623A5/en not_active IP Right Cessation
- 1976-09-21 JP JP51112527A patent/JPS6016417B2/en not_active Expired
- 1976-09-21 IT IT51370/76A patent/IT1073893B/en active
- 1976-09-21 IL IL50522A patent/IL50522A/en unknown
- 1976-09-21 GR GR51742A patent/GR58469B/en unknown
- 1976-09-21 GB GB39099/76A patent/GB1539473A/en not_active Expired
- 1976-09-22 PL PL1976216213A patent/PL117323B1/en unknown
- 1976-09-22 ES ES451768A patent/ES451768A1/en not_active Expired
- 1976-09-22 IE IE2095/76A patent/IE43802B1/en unknown
- 1976-09-22 PL PL19257876A patent/PL192578A1/en not_active IP Right Cessation
- 1976-09-22 FI FI762698A patent/FI61482C/en not_active IP Right Cessation
- 1976-09-22 YU YU2336/76A patent/YU39973B/en unknown
- 1976-09-22 SE SE7610501A patent/SE427839B/en not_active IP Right Cessation
- 1976-09-22 NL NLAANVRAGE7610513,A patent/NL187267C/en not_active IP Right Cessation
- 1976-09-22 CS CS766139A patent/CS222663B2/en unknown
- 1976-09-22 PH PH18928A patent/PH12497A/en unknown
- 1976-09-22 DK DK427876A patent/DK150478C/en active
- 1976-09-22 HU HU76JA00000767A patent/HU172964B/en not_active IP Right Cessation
- 1976-09-22 PT PT65631A patent/PT65631B/en unknown
- 1976-09-22 AT AT0702976A patent/AT363935B/en not_active IP Right Cessation
- 1976-09-23 BG BG7634265A patent/BG27543A3/en unknown
- 1976-09-23 SU SU762405548A patent/SU747424A3/en active
- 1976-09-23 DE DE19762642856 patent/DE2642856A1/en active Granted
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES462065A1 (en) | Thiazolidine derivatives | |
| ES456690A1 (en) | Piperazine and piperidine derivatives | |
| SE416298B (en) | PROCEDURE FOR THE PREPARATION OF NEW BENSIMIDAZOLINON DERIVATIVES | |
| ES453309A1 (en) | Bis(2-phenoxyalkane carboxylic acids) and derivatives thereof and their use as medicaments | |
| ES451768A1 (en) | N-aryl-n-(1-l-4-piperidinyl)-arylacetamides | |
| ES461631A1 (en) | 1-(benzazolylalkyl)piperidine derivatives | |
| SE7604476L (en) | PROCEDURE FOR PREPARING 1- (3,3,3-TRIARYLPROPYL) -4-PHENYL-4-PIPERIDINEMETHANOL COMPOUNDS | |
| ES452200A1 (en) | 1-Benzazolylalkyl-4-substituted-piperidines | |
| ES447150A1 (en) | Pyrazinyl piperazine derivatives | |
| ES455691A1 (en) | N-Benzhydryl-3-methyl-3-(dialkoxy)benzyl-piperazines | |
| GB1471847A (en) | Dibenzofuran derivatives | |
| IL50263A (en) | 4-(2-benzoyloxy or phenoxyalkanoyl-oxy-3-tert-butylaminopropoxy)indole derivatives,their production and pharmaceutical compositions containing them | |
| ES414955A1 (en) | Halogenated 4-(4'-bisphenylyl)-butanols | |
| AU3678371A (en) | l-(3-CYANO-3, 3, DIPHENYLPROPYL)-4-PEHNYLPIP ERINE-4-CARBOXYLIC ACID DERIVATIVES | |
| SU674671A3 (en) | Method of obtaining pyrrolidine derivatives | |
| SE7612961L (en) | TIENAMYCIN DERIVATIVES | |
| ES399003A1 (en) | 2-aryl-amino-imidazoline-2 compounds | |
| ES410934A1 (en) | Indole-carboxylic acid derivatives | |
| ES405647A1 (en) | Procedure for the preparation of new acids 4- (4 bifenilil) -44-hydroxy-butirrics, its esters or lactons. (Machine-translation by Google Translate, not legally binding) | |
| ES398080A1 (en) | 1-(1,2-diphenyl-2-formylvinyl)-4-methylpiperazine and salts thereof with physiologically tolerated acids | |
| ES439180A1 (en) | Substituted hydroxyphenyl-piperidones | |
| ES385714A1 (en) | Preparation of pyrimidylmethyl-pyridinium derivatives | |
| SE412907B (en) | PROCEDURE FOR PREPARING NEW N-2'-CARBOXIFENYL-4-CHLORANTRANIC ACIDS | |
| FR2315932A1 (en) | QUINOLEINE-CARBOXYLIC ACID DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING IT | |
| ES461191A1 (en) | New nn**11piperidinyl*alkyl* aryl carboxysamide derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |