ES405647A1 - Procedure for the preparation of new acids 4- (4 bifenilil) -44-hydroxy-butirrics, its esters or lactons. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new acids 4- (4 bifenilil) -44-hydroxy-butirrics, its esters or lactons. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES405647A1 ES405647A1 ES405647A ES405647A ES405647A1 ES 405647 A1 ES405647 A1 ES 405647A1 ES 405647 A ES405647 A ES 405647A ES 405647 A ES405647 A ES 405647A ES 405647 A1 ES405647 A1 ES 405647A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy
- esters
- general formula
- hydrogen atom
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
Procedure for the preparation of new 4- (4-biphenyl) -4-hydroxy-butyric acids, their esters or lactones of the general formulas I and II **(See formula)** wherein R1 signifies a hydrogen or halogen atom, the cyano, nitro group, or an amino group optionally substituted by an acyl radical with 1 to 4 carbon atoms; R2 means a hydrogen atom, a halogen atom or an alcohol radical with 1 to 3 carbon atoms; R3 signifies a hydrogen or halogen atom; and R4 means a hydrogen atom or an alcoholic group with 1 to 4 carbon atoms, and, if R4 represents a hydrogen atom, its physiologically compatible salts with organic or inorganic acids, characterized in that an amide of 4- (4-Biphenyl) -4-hydroxy-butyric acid of the general formula III **(See formula)** wherein R1 to R3 have the meanings set forth above and A stands for the radical of a substituted or unsubstituted amine a compound of the general formula I, wherein R4 represents a hydrogen atom, if desired in a physiologically compatible salt by by means of an organic or inorganic base, and/or by means of usual methods in its esters of the general formula I, preferably through its acid halide, or in lactones of the general formula II. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19712112715 DE2112715A1 (en) | 1971-03-17 | 1971-03-17 | New 4- (4-biphenylyl) -4-hydroxybutyric acids, their salts, esters and lactones |
Publications (1)
Publication Number | Publication Date |
---|---|
ES405647A1 true ES405647A1 (en) | 1975-07-16 |
Family
ID=5801759
Family Applications (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES400790A Expired ES400790A1 (en) | 1971-03-17 | 1972-03-15 | Procedure for the preparation of new acids 4- (4-bifenilil) - 4 - hydroxibutirics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405645A Expired ES405645A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405647A Expired ES405647A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -44-hydroxy-butirrics, its esters or lactons. (Machine-translation by Google Translate, not legally binding) |
ES405644A Expired ES405644A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (u bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405643A Expired ES405643A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405651A Expired ES405651A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405646A Expired ES405646A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405648A Expired ES405648A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405649A Expired ES405649A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405650A Expired ES405650A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES400790A Expired ES400790A1 (en) | 1971-03-17 | 1972-03-15 | Procedure for the preparation of new acids 4- (4-bifenilil) - 4 - hydroxibutirics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405645A Expired ES405645A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
Family Applications After (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES405644A Expired ES405644A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (u bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405643A Expired ES405643A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405651A Expired ES405651A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405646A Expired ES405646A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405648A Expired ES405648A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405649A Expired ES405649A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
ES405650A Expired ES405650A1 (en) | 1971-03-17 | 1972-08-08 | Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding) |
Country Status (6)
Country | Link |
---|---|
AT (13) | AT318585B (en) |
CH (3) | CH583679A5 (en) |
DE (1) | DE2112715A1 (en) |
DK (1) | DK132943C (en) |
ES (10) | ES400790A1 (en) |
FR (1) | FR2279385A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5973579A (en) * | 1982-10-19 | 1984-04-25 | Kotobuki Seiyaku Kk | Benzofuran or benzothiophene derivative, diuretic agent containing said compound as active constituent and preparation thereof |
US4777288A (en) * | 1987-06-11 | 1988-10-11 | Pfizer Inc. | Process for preparing a 4,4-diphenylbutanoic acid derivative |
AT401513B (en) * | 1994-12-22 | 1996-09-25 | Chemie Linz Gmbh | METHOD FOR PRODUCING 2-HYDROXY-4-PHENYLBUTTERIC ACID |
FR2817256B1 (en) | 2000-11-27 | 2005-07-15 | Univ Pasteur | DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND ITS SUPERIOR APPROACHES AS GAMMA-HYDROXYBUTYRATE (GHB) RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES |
AR044152A1 (en) | 2003-05-09 | 2005-08-24 | Bayer Corp | RENTAL DERIVATIVES, METHOD OF PREPARATION AND USE FOR THE TREATMENT OF OBESITY |
-
1971
- 1971-03-17 DE DE19712112715 patent/DE2112715A1/en active Pending
-
1972
- 1972-03-14 CH CH371572A patent/CH583679A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH1083875A patent/CH585173A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH1083775A patent/CH586178A5/xx not_active IP Right Cessation
- 1972-03-15 ES ES400790A patent/ES400790A1/en not_active Expired
- 1972-03-16 AT AT00022/73A patent/AT318585B/en not_active IP Right Cessation
- 1972-03-16 AT AT222172A patent/AT317188B/en not_active IP Right Cessation
- 1972-03-16 AT AT00017/73A patent/AT319220B/en not_active IP Right Cessation
- 1972-03-16 DK DK124272A patent/DK132943C/en active
- 1972-03-16 AT AT2373A patent/AT318586B/en active
- 1972-03-16 AT AT00019/73A patent/AT320620B/en not_active IP Right Cessation
- 1972-03-16 AT AT00014/73A patent/AT319219B/en not_active IP Right Cessation
- 1972-03-16 AT AT00016/73A patent/AT317876B/en not_active IP Right Cessation
- 1972-03-16 AT AT00025/73A patent/AT320622B/en not_active IP Right Cessation
- 1972-03-16 AT AT00021/73A patent/AT319221B/en not_active IP Right Cessation
- 1972-03-16 AT AT2073A patent/AT317878B/en active
- 1972-03-16 AT AT1873A patent/AT317877B/en active
- 1972-08-08 ES ES405645A patent/ES405645A1/en not_active Expired
- 1972-08-08 ES ES405647A patent/ES405647A1/en not_active Expired
- 1972-08-08 ES ES405644A patent/ES405644A1/en not_active Expired
- 1972-08-08 ES ES405643A patent/ES405643A1/en not_active Expired
- 1972-08-08 ES ES405651A patent/ES405651A1/en not_active Expired
- 1972-08-08 ES ES405646A patent/ES405646A1/en not_active Expired
- 1972-08-08 ES ES405648A patent/ES405648A1/en not_active Expired
- 1972-08-08 ES ES405649A patent/ES405649A1/en not_active Expired
- 1972-08-08 ES ES405650A patent/ES405650A1/en not_active Expired
-
1973
- 1973-01-02 AT AT1573A patent/AT317875B/en active
- 1973-01-02 AT AT00024/73A patent/AT320621B/en not_active IP Right Cessation
-
1974
- 1974-12-19 FR FR7442065A patent/FR2279385A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DK132943B (en) | 1976-03-01 |
DE2112715A1 (en) | 1972-10-05 |
DK132943C (en) | 1976-08-02 |
AT317877B (en) | 1974-09-25 |
AT319220B (en) | 1974-12-10 |
AT320622B (en) | 1975-02-25 |
ES405650A1 (en) | 1975-07-16 |
ES405646A1 (en) | 1975-07-16 |
AT318586B (en) | 1974-10-25 |
AT317876B (en) | 1974-09-25 |
AT320620B (en) | 1975-02-25 |
CH583679A5 (en) | 1977-01-14 |
CH586178A5 (en) | 1977-03-31 |
AT317878B (en) | 1974-09-25 |
ES405649A1 (en) | 1975-07-16 |
ES405645A1 (en) | 1975-07-16 |
AT318585B (en) | 1974-10-25 |
AT317188B (en) | 1974-08-12 |
ES405648A1 (en) | 1975-07-16 |
ES405644A1 (en) | 1975-07-16 |
ES405651A1 (en) | 1975-07-16 |
CH585173A5 (en) | 1977-02-28 |
ES400790A1 (en) | 1975-01-16 |
FR2279385A1 (en) | 1976-02-20 |
ES405643A1 (en) | 1975-07-16 |
AT320621B (en) | 1975-02-25 |
AT319219B (en) | 1974-12-10 |
AT319221B (en) | 1974-12-10 |
AT317875B (en) | 1974-09-25 |
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