SE7610501L - NEW N-ARYL-N (1-L-4-PIPERIDINYL) -ARYLACETAMIDES - Google Patents

NEW N-ARYL-N (1-L-4-PIPERIDINYL) -ARYLACETAMIDES

Info

Publication number
SE7610501L
SE7610501L SE7610501A SE7610501A SE7610501L SE 7610501 L SE7610501 L SE 7610501L SE 7610501 A SE7610501 A SE 7610501A SE 7610501 A SE7610501 A SE 7610501A SE 7610501 L SE7610501 L SE 7610501L
Authority
SE
Sweden
Prior art keywords
arylacetamides
piperidinyl
aryl
new
formula
Prior art date
Application number
SE7610501A
Other languages
Swedish (sv)
Other versions
SE427839B (en
Inventor
S Sanczuk
H K F Hermans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SE7610501L publication Critical patent/SE7610501L/en
Publication of SE427839B publication Critical patent/SE427839B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

N-Aryl-N-(4-piperidinyl)arylacetamides of the formula <IMAGE> and their salts with acids, the substituents in the formula being defined in Claim 1, are prepared. These compounds are obtained by acylating corresponding piperidine derivatives with an arylacetyl halide. The resulting compounds can be used for the drug therapy of cardiac arrhythmias.
SE7610501A 1975-09-23 1976-09-22 ANALOGY PROCEDURES FOR THE PREPARATION OF N-ARYL-N- (1-L-4-PIPERIDINYL) -ARYL-ACETAMIDES SE427839B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61513175A 1975-09-23 1975-09-23
US71375676A 1976-08-12 1976-08-12

Publications (2)

Publication Number Publication Date
SE7610501L true SE7610501L (en) 1977-03-24
SE427839B SE427839B (en) 1983-05-09

Family

ID=27087421

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7610501A SE427839B (en) 1975-09-23 1976-09-22 ANALOGY PROCEDURES FOR THE PREPARATION OF N-ARYL-N- (1-L-4-PIPERIDINYL) -ARYL-ACETAMIDES

Country Status (29)

Country Link
JP (1) JPS6016417B2 (en)
AT (1) AT363935B (en)
AU (1) AU510029B2 (en)
BG (1) BG27543A3 (en)
CA (1) CA1068271A (en)
CH (1) CH628623A5 (en)
CS (1) CS222663B2 (en)
DE (1) DE2642856A1 (en)
DK (1) DK150478C (en)
ES (1) ES451768A1 (en)
FI (1) FI61482C (en)
FR (1) FR2325377A1 (en)
GB (1) GB1539473A (en)
GR (1) GR58469B (en)
HU (1) HU172964B (en)
IE (1) IE43802B1 (en)
IL (1) IL50522A (en)
IT (1) IT1073893B (en)
LU (1) LU75837A1 (en)
NL (1) NL187267C (en)
NO (1) NO147672C (en)
NZ (1) NZ181972A (en)
PH (1) PH12497A (en)
PL (2) PL192578A1 (en)
PT (1) PT65631B (en)
RO (1) RO70079A (en)
SE (1) SE427839B (en)
SU (1) SU747424A3 (en)
YU (1) YU39973B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA765684B (en) * 1975-09-23 1978-04-26 Janssen Pharmaceutica Nv Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
JPS62260786A (en) * 1986-05-08 1987-11-13 株式会社ヘキトク Line system for manufacturing smoked roof tile
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Fast Dissociting Dopamine 2 Receptor Antagonists
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Fast Dissociating Dopamine 2 Receptor Antagonists
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Fast -Dissociating Dopamine 2 Receptor Antagonists
KR20100016620A (en) 2007-04-23 2010-02-12 얀센 파마슈티카 엔.브이. 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists
US20100137368A1 (en) * 2007-04-23 2010-06-03 Janssen Pharmaceutica N.V. Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists
MX2009011416A (en) 2007-04-23 2009-11-05 Janssen Pharmaceutica Nv Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists.
RU2502734C2 (en) 2008-07-03 2013-12-27 Янссен Фармацевтика Нв Substituted 6-(1-piperazinyl)-pyridazines as 5-ht6 receptor antagonists
CN102171189B (en) 2008-07-31 2013-11-20 詹森药业有限公司 Piperazin-1-yl-trifluoromethyl-substituted-pyridines as fast dissociating dopamine 2 receptor antagonists

Also Published As

Publication number Publication date
FR2325377A1 (en) 1977-04-22
CA1068271A (en) 1979-12-18
IL50522A (en) 1979-09-30
IT1073893B (en) 1985-04-17
FI61482C (en) 1982-08-10
AT363935B (en) 1981-09-10
YU233676A (en) 1983-01-21
HU172964B (en) 1979-01-28
SU747424A3 (en) 1980-07-23
RO70079A (en) 1982-10-26
PL192578A1 (en) 1979-02-26
AU1787876A (en) 1978-03-23
PT65631B (en) 1978-07-05
DE2642856A1 (en) 1977-03-24
PH12497A (en) 1979-04-05
IE43802L (en) 1977-03-23
IL50522A0 (en) 1976-11-30
JPS6016417B2 (en) 1985-04-25
CH628623A5 (en) 1982-03-15
DK150478B (en) 1987-03-09
LU75837A1 (en) 1977-05-04
DE2642856C2 (en) 1990-06-21
GR58469B (en) 1977-10-14
NO147672B (en) 1983-02-14
BG27543A3 (en) 1979-11-12
ATA702976A (en) 1981-02-15
DK427876A (en) 1977-03-24
AU510029B2 (en) 1980-06-05
SE427839B (en) 1983-05-09
NZ181972A (en) 1978-07-28
IE43802B1 (en) 1981-06-03
CS222663B2 (en) 1983-07-29
ES451768A1 (en) 1978-05-01
NL7610513A (en) 1977-03-25
FI61482B (en) 1982-04-30
NO147672C (en) 1983-05-25
YU39973B (en) 1985-06-30
FI762698A (en) 1977-03-24
GB1539473A (en) 1979-01-31
JPS5239683A (en) 1977-03-28
PT65631A (en) 1976-10-01
DK150478C (en) 1987-10-05
FR2325377B1 (en) 1980-04-18
NL187267B (en) 1991-03-01
PL117323B1 (en) 1981-07-31
NO763054L (en) 1977-03-24
NL187267C (en) 1991-08-01

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