ES412885A2 - Procedure for the preparation of derivatives of (alcoxy-4-piperidine-alcohil) -10-phenotyazine. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of derivatives of (alcoxy-4-piperidine-alcohil) -10-phenotyazine. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES412885A2
ES412885A2 ES412885A ES412885A ES412885A2 ES 412885 A2 ES412885 A2 ES 412885A2 ES 412885 A ES412885 A ES 412885A ES 412885 A ES412885 A ES 412885A ES 412885 A2 ES412885 A2 ES 412885A2
Authority
ES
Spain
Prior art keywords
formula
derivatives
translation
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES412885A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES412885A2 publication Critical patent/ES412885A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Improvements introduced in the object of the main patent No. 402,731 applied for on May 13, 1972 for: "Procedure for the preparation of derivatives of (alkoxy-4-piperidino-alcoholic) -10-phenothiazines" and their pharmaceutically acceptable addition salts, according to which when said derivatives respond to the formula: **(See formula)** in which R1 represents an ethyl, propyl, butyl or methy1-1-hexyl radical, said improvements are characterized in that (chloro-3-propyl) -10-trifluoromethyl-2-phenothiazine is made to act of formula **(See formula)** with a piperidine derivative of the formula **(See formula)** to obtain {[(hydroxy-2-ethoxy) -4-piperidino] -3-propyl} -10-trifluoromethyl-2-phenothiazine and make the latter act with an acid chloride of formula Cl-CO-R1 in which R1 has the aforementioned meaning and, if desired, acting on the obtained product an acid or mineral or pharmaceutically compatible organic to form the salt thereof. (Machine-translation by Google Translate, not legally binding)
ES412885A 1972-03-22 1973-03-21 Procedure for the preparation of derivatives of (alcoxy-4-piperidine-alcohil) -10-phenotyazine. (Machine-translation by Google Translate, not legally binding) Expired ES412885A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7210009A FR2176527A2 (en) 1972-03-22 1972-03-22 Phenothiazines derivs - with delayed neuroleptic antihistaminic, analgesic and spasmolytic activity

Publications (1)

Publication Number Publication Date
ES412885A2 true ES412885A2 (en) 1977-07-01

Family

ID=9095628

Family Applications (1)

Application Number Title Priority Date Filing Date
ES412885A Expired ES412885A2 (en) 1972-03-22 1973-03-21 Procedure for the preparation of derivatives of (alcoxy-4-piperidine-alcohil) -10-phenotyazine. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
ES (1) ES412885A2 (en)
FR (1) FR2176527A2 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1344593A (en) * 1961-11-25 1963-11-29 Boehringer & Soehne Gmbh Process for the preparation of novel alkoxy-piperidine derivatives and their salts

Also Published As

Publication number Publication date
FR2176527A2 (en) 1973-11-02
FR2176527B2 (en) 1975-04-25

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Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20170704