ES392848A1 - Indenopyrrole derivatives - Google Patents

Indenopyrrole derivatives

Info

Publication number
ES392848A1
ES392848A1 ES392848A ES392848A ES392848A1 ES 392848 A1 ES392848 A1 ES 392848A1 ES 392848 A ES392848 A ES 392848A ES 392848 A ES392848 A ES 392848A ES 392848 A1 ES392848 A1 ES 392848A1
Authority
ES
Spain
Prior art keywords
groups
lower alkyl
formula
toxic
alq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES392848A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allen and Hanburys Ltd
Original Assignee
Allen and Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10333570&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES392848(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allen and Hanburys Ltd filed Critical Allen and Hanburys Ltd
Publication of ES392848A1 publication Critical patent/ES392848A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A procedure for the preparation of new indenopyrrole derivatives of general formula **(See formula)** where R1 is a hydrogen atom or a carbamoyl or dialkylcarbamoyl radical, a lower alkyl or alkenyl group, the groups of which may optionally be substituted with one or more substituted aryl, hydroxy, oxo or amino groups; R2 and R3 which may be the same or different, represent hydrogen atoms, straight or branched chain lower alkyl groups or an OR1 or O.CD.Alq group, where R1 has the meaning given above and Alq is alkyl; R4 and R5, which may be the same or different, represent hydrogen atoms or lower alkyl or phenyl groups; and R6 represents a hydrogen atom; and its non-toxic and pharmaceutically acceptable salts whose procedure is to reduce the corresponding lactam of formula **(See formula)** where R1-R5 have the meaning given above, if desired with subsequent conversion of one or more of the R1-R5 groups to other groups within the given meanings; The compounds are isolated if desired in the form of non-toxic and pharmaceutically acceptable salts that can later be converted into another salt. (Machine-translation by Google Translate, not legally binding)
ES392848A 1970-07-02 1971-07-02 Indenopyrrole derivatives Expired ES392848A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3212070 1970-07-02

Publications (1)

Publication Number Publication Date
ES392848A1 true ES392848A1 (en) 1974-07-16

Family

ID=10333570

Family Applications (2)

Application Number Title Priority Date Filing Date
ES392848A Expired ES392848A1 (en) 1970-07-02 1971-07-02 Indenopyrrole derivatives
ES419386A Expired ES419386A1 (en) 1970-07-02 1973-10-05 Indenopyrrole derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES419386A Expired ES419386A1 (en) 1970-07-02 1973-10-05 Indenopyrrole derivatives

Country Status (12)

Country Link
AT (2) AT310731B (en)
BE (1) BE769303A (en)
CA (1) CA948206A (en)
CH (1) CH570980A5 (en)
DE (1) DE2132810A1 (en)
ES (2) ES392848A1 (en)
FR (1) FR2100854B1 (en)
GB (1) GB1351754A (en)
IL (1) IL37146A (en)
NL (1) NL7109212A (en)
SE (1) SE377117B (en)
ZA (1) ZA714137B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878225A (en) * 1973-03-01 1975-04-15 Hoechst Co American Condensed pyrroles bearing an N-phenyl substituent
GR72713B (en) * 1976-09-15 1983-12-01 American Cyanamid Co
US5387590A (en) 1989-08-30 1995-02-07 Pfizer Inc. Benzazabicyclic carbamates as novel cholinesterase inhibitors
ES2103816T3 (en) * 1990-07-12 1997-10-01 Pfizer INDANO PIRROLIDINE CARBAMATES.
CN102381961B (en) * 2011-09-03 2014-01-15 四川大学 3-phenyl glutaric acid compound, preparation method and purpose thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1277789A (en) * 1969-09-08 1972-06-14 Logeais Labor Jacques Improvements in or relating to new polycyclic pyrrole derivatives

Also Published As

Publication number Publication date
ZA714137B (en) 1972-03-29
FR2100854B1 (en) 1974-11-15
BE769303A (en) 1971-12-30
AT310731B (en) 1973-10-10
SE377117B (en) 1975-06-23
ES419386A1 (en) 1976-07-01
FR2100854A1 (en) 1972-03-24
DE2132810A1 (en) 1972-01-05
NL7109212A (en) 1972-01-04
CA948206A (en) 1974-05-28
CH570980A5 (en) 1975-12-31
GB1351754A (en) 1974-05-01
IL37146A0 (en) 1971-08-25
AT305996B (en) 1973-03-26
IL37146A (en) 1974-10-22

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