GB1380682A - Aminoisoquinolines - Google Patents
AminoisoquinolinesInfo
- Publication number
- GB1380682A GB1380682A GB4159372A GB4159372A GB1380682A GB 1380682 A GB1380682 A GB 1380682A GB 4159372 A GB4159372 A GB 4159372A GB 4159372 A GB4159372 A GB 4159372A GB 1380682 A GB1380682 A GB 1380682A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- compound
- substituted
- phso
- alkylsulphonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
1380682 2-Aminoisoquinoline derivatives GRUPPO LEPETIT SpA 7 Sept 1972 [12 June 1972] 41593/72 Heading C2C The invention comprises compounds of formula wherein one of X, Y is O and the other is H 2 ; R is H, up to C 8 alkyl or alkynyl, up to C 8 alkenyl (possibly substituted by Ph, which may be substituted), cycloalkenyl, C 1-8 alkylsulphonyl or PhSO 2 ; and R 1 is up to C 8 alkenyl (possibly substituted as above) or alkynyl, or cycloalkenyl, or RR 1 N is* optionally substituted Phup to C 8 -alkenylideneamino. These compounds are prepared by (a) reacting a corresponding compound where R 1 is H, with R 1 - halide, (b) hydrolysing a compound where R is C 1-8 alkylsulphonyl or PhSO 2 , to obtain the compounds where R is H, or (c) in case *, reacting a compound where R = R 1 = H with an appropriate arylalkenal. Therapeutic compositions for oral, parenteral or rectal administration comprise compounds of the above formula, which have antiinflammatory activity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT25549/72A IT1045206B (en) | 1972-06-12 | 1972-06-12 | AMINOISOCHINOLINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1380682A true GB1380682A (en) | 1975-01-15 |
Family
ID=11217059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4159372A Expired GB1380682A (en) | 1972-06-12 | 1972-09-07 | Aminoisoquinolines |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5037197B2 (en) |
| AR (1) | AR204388A1 (en) |
| AT (1) | AT325048B (en) |
| AU (1) | AU470823B2 (en) |
| BE (1) | BE788901R (en) |
| CH (2) | CH562802A5 (en) |
| DE (1) | DE2244832A1 (en) |
| ES (1) | ES408635A1 (en) |
| FI (1) | FI50974C (en) |
| FR (1) | FR2187329B2 (en) |
| GB (1) | GB1380682A (en) |
| HU (1) | HU165564B (en) |
| IT (1) | IT1045206B (en) |
| NL (1) | NL7214650A (en) |
| PL (1) | PL89031B1 (en) |
| SU (1) | SU444365A3 (en) |
| ZA (1) | ZA726158B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3037984A (en) * | 1960-01-27 | 1962-06-05 | Lakeside Lab Inc | Derivatives of n-amino-1, 2, 3, 4-tetrahydroisoquinoline |
-
0
- BE BE788901D patent/BE788901R/en active
-
1972
- 1972-01-01 AR AR244108A patent/AR204388A1/en active
- 1972-06-12 IT IT25549/72A patent/IT1045206B/en active
- 1972-09-07 GB GB4159372A patent/GB1380682A/en not_active Expired
- 1972-09-08 ZA ZA726158A patent/ZA726158B/en unknown
- 1972-09-12 FI FI722500A patent/FI50974C/en active
- 1972-09-13 DE DE2244832A patent/DE2244832A1/en active Pending
- 1972-09-14 PL PL1972157754A patent/PL89031B1/pl unknown
- 1972-09-15 HU HULE667A patent/HU165564B/hu unknown
- 1972-09-15 AT AT793572A patent/AT325048B/en not_active IP Right Cessation
- 1972-09-18 SU SU1830979A patent/SU444365A3/en active
- 1972-09-18 AU AU46767/72A patent/AU470823B2/en not_active Expired
- 1972-10-02 CH CH1436172A patent/CH562802A5/xx not_active IP Right Cessation
- 1972-10-02 CH CH217174A patent/CH564535A5/xx not_active IP Right Cessation
- 1972-10-30 NL NL7214650A patent/NL7214650A/xx unknown
- 1972-11-08 JP JP47111339A patent/JPS5037197B2/ja not_active Expired
- 1972-11-16 ES ES408635A patent/ES408635A1/en not_active Expired
- 1972-12-21 FR FR7245729A patent/FR2187329B2/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU165564B (en) | 1974-09-28 |
| JPS4930380A (en) | 1974-03-18 |
| CH564535A5 (en) | 1975-07-31 |
| FR2187329A2 (en) | 1974-01-18 |
| FI50974C (en) | 1976-09-10 |
| AT325048B (en) | 1975-09-25 |
| NL7214650A (en) | 1973-12-14 |
| IT1045206B (en) | 1980-05-10 |
| BE788901R (en) | 1973-01-02 |
| FR2187329B2 (en) | 1976-03-05 |
| AU4676772A (en) | 1974-03-28 |
| AU470823B2 (en) | 1976-04-01 |
| AR204388A1 (en) | 1976-02-06 |
| DE2244832A1 (en) | 1974-01-10 |
| ES408635A1 (en) | 1975-10-16 |
| PL89031B1 (en) | 1976-10-30 |
| JPS5037197B2 (en) | 1975-12-01 |
| SU444365A3 (en) | 1974-09-25 |
| ZA726158B (en) | 1973-06-27 |
| CH562802A5 (en) | 1975-06-13 |
| FI50974B (en) | 1976-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |