FI59253C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-hydroxi-2h-tieno(2,3-e) och (3,4-e)-1,2-tiazin-3-karboxamid-1,1-dioxid-derivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-hydroxi-2h-tieno(2,3-e) och (3,4-e)-1,2-tiazin-3-karboxamid-1,1-dioxid-derivat Download PDF

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Publication number
FI59253C
FI59253C FI752398A FI752398A FI59253C FI 59253 C FI59253 C FI 59253C FI 752398 A FI752398 A FI 752398A FI 752398 A FI752398 A FI 752398A FI 59253 C FI59253 C FI 59253C
Authority
FI
Finland
Prior art keywords
methyl
pyridyl
formula
hydroxy
compound
Prior art date
Application number
FI752398A
Other languages
English (en)
Finnish (fi)
Other versions
FI752398A (no
FI59253B (fi
Inventor
Otto Hromatka
Dieter Binder
Rudolf Pfister
Paul Zeller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1158274A external-priority patent/CH608500A5/de
Priority claimed from CH1215774A external-priority patent/CH608501A5/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI752398A publication Critical patent/FI752398A/fi
Application granted granted Critical
Publication of FI59253B publication Critical patent/FI59253B/fi
Publication of FI59253C publication Critical patent/FI59253C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Manufacturing Of Printed Wiring (AREA)
  • Electroplating Methods And Accessories (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI752398A 1974-08-26 1975-08-26 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-hydroxi-2h-tieno(2,3-e) och (3,4-e)-1,2-tiazin-3-karboxamid-1,1-dioxid-derivat FI59253C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1158274 1974-08-26
CH1158274A CH608500A5 (en) 1974-08-26 1974-08-26 Process for the preparation of thiazine derivatives
CH1215774A CH608501A5 (en) 1974-09-09 1974-09-09 Process for the preparation of thiazine derivatives
CH1215774 1974-09-09

Publications (3)

Publication Number Publication Date
FI752398A FI752398A (no) 1976-02-27
FI59253B FI59253B (fi) 1981-03-31
FI59253C true FI59253C (fi) 1981-07-10

Family

ID=25708582

Family Applications (1)

Application Number Title Priority Date Filing Date
FI752398A FI59253C (fi) 1974-08-26 1975-08-26 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-hydroxi-2h-tieno(2,3-e) och (3,4-e)-1,2-tiazin-3-karboxamid-1,1-dioxid-derivat

Country Status (20)

Country Link
JP (1) JPS5826758B2 (no)
AR (1) AR216288A1 (no)
AT (1) AT350064B (no)
BR (1) BR7505463A (no)
DD (1) DD124119A5 (no)
DE (1) DE2537070A1 (no)
DK (1) DK137835B (no)
FI (1) FI59253C (no)
FR (3) FR2282893A1 (no)
GB (1) GB1519811A (no)
HU (1) HU173739B (no)
IE (1) IE41457B1 (no)
IL (1) IL47877A (no)
LU (2) LU73257A1 (no)
NL (2) NL183582C (no)
NO (1) NO146096C (no)
PL (1) PL106076B1 (no)
SE (1) SE412066B (no)
SU (1) SU603338A3 (no)
YU (1) YU40266B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2704485A1 (de) * 1977-02-03 1978-08-10 Thomae Gmbh Dr K Neue 2,5-dihydro-1,2-thiazino eckige klammer auf 5,6-b eckige klammer zu indol-3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
LU78009A1 (de) * 1977-08-22 1979-05-23 Hoffmann La Roche Verfahren zur herstellung von thiazinderivaten
AU518216B2 (en) 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
ZA784958B (en) * 1977-09-06 1979-08-29 Hoffmann La Roche Thiazine derivatives
DE2838377A1 (de) * 1978-09-02 1980-03-20 Thomae Gmbh Dr K Neue 4-hydroxy-2h eckige klammer auf 1 eckige klammer zu benzothieno eckige klammer auf 2,3-e eckige klammer zu -1,2- thiazin-3-carboxamid-1,1-dioxide sowie deren salze, deren verwendung und verfahren zu ihrer herstellung
AU5811280A (en) * 1979-06-13 1980-12-18 F. Hoffmann-La Roche Ag Thiazine derivatives
JPS58109492A (ja) * 1981-12-22 1983-06-29 Mitsui Toatsu Chem Inc チエノチアジン誘導体およびそれを含有する医薬組成物
ATE26720T1 (de) * 1982-09-09 1987-05-15 Hoffmann La Roche Thieno(2,3-e)-1,2-thiazin-derivate.
JPS60163533U (ja) * 1984-04-02 1985-10-30 ホシデン株式会社 リ−ル台の制動装置
JPH0318748Y2 (no) * 1985-12-18 1991-04-19
ATA39088A (de) 1988-02-18 1990-06-15 Binder Dieter Dr Basisch substituierte thienoisothiazol-3(2h)-on-1,1-dioxide und ihre pharmazeutisch vertraeglichen salze, verfahren zu ihrer herstellung und ihre verwendung
AT400437B (de) * 1993-12-14 1995-12-27 Chem Pharm Forsch Gmbh Neue n-heterocyclische thienothiazincarboxamide, verfahren zu ihrer herstellung und ihre verwendung
AT400568B (de) * 1994-05-18 1996-01-25 Chem Pharm Forsch Gmbh Neue n-heterocyclische thienothiazincarboxamide, verfahren zu ihrer herstellung und ihre verwendung
EP0658559A1 (de) * 1993-12-14 1995-06-21 Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. Thienothiazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als 5-dipoxygenase und Cyclooxygenaseinhibitoren
US5538966A (en) * 1994-01-21 1996-07-23 Alcon Laboratories, Inc. Carbonic anhydrase inhibitors
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
CN1171892C (zh) * 2001-06-25 2004-10-20 李晶 具有抗炎镇痛活性的噻吩并噻嗪化合物及其制备方法和用途

Also Published As

Publication number Publication date
NO146096B (no) 1982-04-19
SE412066B (sv) 1980-02-18
AR216288A1 (es) 1979-12-14
IE41457L (en) 1976-02-26
DK381175A (no) 1976-02-27
SE7509446L (sv) 1976-02-27
JPS5148694A (no) 1976-04-26
FI752398A (no) 1976-02-27
JPS5826758B2 (ja) 1983-06-04
NL183582B (nl) 1988-07-01
AU8418675A (en) 1977-02-24
AT350064B (de) 1979-05-10
GB1519811A (en) 1978-08-02
NO752932L (no) 1976-02-27
FR2309558B1 (no) 1979-05-04
DK137835C (no) 1978-10-16
LU73257A1 (no) 1977-04-15
FR2303803A1 (fr) 1976-10-08
DK137835B (da) 1978-05-16
IL47877A0 (en) 1975-11-25
DD124119A5 (no) 1977-02-02
IE41457B1 (en) 1980-01-02
LU88312I2 (de) 1994-09-09
NO146096C (no) 1982-07-28
FR2303803B1 (no) 1979-07-13
SU603338A3 (ru) 1978-04-15
PL106076B1 (pl) 1979-11-30
NL930080I2 (nl) 1994-01-03
YU216675A (en) 1982-08-31
NL930080I1 (nl) 1993-09-16
DE2537070C2 (no) 1987-06-25
YU40266B (en) 1985-12-31
FR2282893A1 (fr) 1976-03-26
HU173739B (hu) 1979-08-28
FR2309558A1 (fr) 1976-11-26
ATA655975A (de) 1978-10-15
DE2537070A1 (de) 1976-03-18
NL183582C (nl) 1988-12-01
IL47877A (en) 1978-10-31
BR7505463A (pt) 1976-08-03
FI59253B (fi) 1981-03-31
FR2282893B1 (no) 1980-05-16
NL7510057A (nl) 1976-03-01

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Owner name: F. HOFFMANN-LA ROCHE AG