FI58135C - Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat Download PDF

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Publication number
FI58135C
FI58135C FI773814A FI773814A FI58135C FI 58135 C FI58135 C FI 58135C FI 773814 A FI773814 A FI 773814A FI 773814 A FI773814 A FI 773814A FI 58135 C FI58135 C FI 58135C
Authority
FI
Finland
Prior art keywords
group
alkyl
substituted
formula
hellebrigenin
Prior art date
Application number
FI773814A
Other languages
English (en)
Finnish (fi)
Other versions
FI773814A (fi
FI58135B (fi
Inventor
Otto Isaac
Klaus Posselt
Horst Uthemann
Klaus Thiemer
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of FI773814A publication Critical patent/FI773814A/fi
Publication of FI58135B publication Critical patent/FI58135B/fi
Application granted granted Critical
Publication of FI58135C publication Critical patent/FI58135C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI773814A 1976-12-17 1977-12-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat FI58135C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB52759/76A GB1577633A (en) 1976-12-17 1976-12-17 Acyl derivatives of hellebrigenin
GB5275976 1976-12-17

Publications (3)

Publication Number Publication Date
FI773814A FI773814A (fi) 1978-06-18
FI58135B FI58135B (fi) 1980-08-29
FI58135C true FI58135C (fi) 1980-12-10

Family

ID=10465185

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773814A FI58135C (fi) 1976-12-17 1977-12-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat

Country Status (15)

Country Link
JP (1) JPS591279B2 (fr)
AT (1) AT372391B (fr)
BE (1) BE861968A (fr)
CH (1) CH639107A5 (fr)
DD (1) DD133151A5 (fr)
DE (1) DE2755122C2 (fr)
ES (2) ES465135A1 (fr)
FI (1) FI58135C (fr)
FR (1) FR2374336A1 (fr)
GB (1) GB1577633A (fr)
HU (1) HU176767B (fr)
IT (1) IT1113251B (fr)
PL (1) PL110178B1 (fr)
SU (2) SU751328A3 (fr)
ZA (1) ZA777494B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61158784U (fr) * 1985-03-25 1986-10-01
EP1108702A1 (fr) * 1999-12-13 2001-06-20 Kvaerner Process Technology Limited Procédé pour la coproduction de diols aliphatiques et d'éthers cycliques
WO2010102673A1 (fr) * 2009-03-13 2010-09-16 Unibioscreen S.A. Hellébrine et dérivés d'hellébrigénine
SG10201503290TA (en) * 2010-04-27 2015-06-29 Pharma Mar Sa Anticancer steroidal lactones unsaturated in position 7 (8)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1901484A1 (de) * 1969-01-14 1970-10-29 Hoechst Ag Herzwirksame Oxyester von Steroid-Cardenoliden und -Bufandienoliden und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
ZA777494B (en) 1979-02-28
DE2755122A1 (de) 1978-06-22
FI773814A (fi) 1978-06-18
AT372391B (de) 1983-09-26
IT1113251B (it) 1986-01-20
ES465135A1 (es) 1978-10-01
DE2755122C2 (de) 1983-06-30
DD133151A5 (de) 1978-12-13
ATA903877A (de) 1983-02-15
CH639107A5 (de) 1983-10-31
JPS5395956A (en) 1978-08-22
SU795487A3 (ru) 1981-01-07
JPS591279B2 (ja) 1984-01-11
FR2374336B1 (fr) 1980-11-07
ES465136A1 (es) 1979-01-01
FI58135B (fi) 1980-08-29
SU751328A3 (ru) 1980-07-23
BE861968A (fr) 1978-06-16
PL110178B1 (en) 1980-07-31
PL203030A1 (pl) 1979-03-26
HU176767B (en) 1981-05-28
FR2374336A1 (fr) 1978-07-13
GB1577633A (en) 1980-10-29

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Owner name: DEGUSSA AG