ES465135A1 - Procedimiento para la preparacion de nuevos derivados de he-lebrigenina. - Google Patents
Procedimiento para la preparacion de nuevos derivados de he-lebrigenina.Info
- Publication number
- ES465135A1 ES465135A1 ES465135A ES465135A ES465135A1 ES 465135 A1 ES465135 A1 ES 465135A1 ES 465135 A ES465135 A ES 465135A ES 465135 A ES465135 A ES 465135A ES 465135 A1 ES465135 A1 ES 465135A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- substituted
- hellebrigenin
- alkoxyalkoxy
- acyl derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Procedimiento para la preparación de nuevos derivados de helerigenina de la fórmula general***(Ver fórmula)en la que R es un radical alquenilo C2-C6un radical halogenoalcohilo-C1-C6un radical cicloalcohilo-C3-C6un radical alcohilo-C3-C18un radical alcohilo-C3-C10 sustituido con un grupo carbalcoxi-C2-C5 o con un grupo carboxies un radical alcoxialcohilo-C2-C6un radical alcoxialcohilo-C2-C6 sustituido con un grupo carboxies un radical feniloun radical fenilo sustituido con grupos nitro.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB52759/76A GB1577633A (en) | 1976-12-17 | 1976-12-17 | Acyl derivatives of hellebrigenin |
Publications (1)
Publication Number | Publication Date |
---|---|
ES465135A1 true ES465135A1 (es) | 1978-10-01 |
Family
ID=10465185
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES465136A Expired ES465136A1 (es) | 1976-12-17 | 1977-12-16 | Procedimiento para la preparacion de nuevos derivados de he-lebrigenina |
ES465135A Expired ES465135A1 (es) | 1976-12-17 | 1977-12-16 | Procedimiento para la preparacion de nuevos derivados de he-lebrigenina. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES465136A Expired ES465136A1 (es) | 1976-12-17 | 1977-12-16 | Procedimiento para la preparacion de nuevos derivados de he-lebrigenina |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS591279B2 (es) |
AT (1) | AT372391B (es) |
BE (1) | BE861968A (es) |
CH (1) | CH639107A5 (es) |
DD (1) | DD133151A5 (es) |
DE (1) | DE2755122C2 (es) |
ES (2) | ES465136A1 (es) |
FI (1) | FI58135C (es) |
FR (1) | FR2374336A1 (es) |
GB (1) | GB1577633A (es) |
HU (1) | HU176767B (es) |
IT (1) | IT1113251B (es) |
PL (1) | PL110178B1 (es) |
SU (2) | SU751328A3 (es) |
ZA (1) | ZA777494B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61158784U (es) * | 1985-03-25 | 1986-10-01 | ||
EP1108702A1 (en) * | 1999-12-13 | 2001-06-20 | Kvaerner Process Technology Limited | Process for the co-production of aliphatic diols and cyclic ethers |
WO2010102673A1 (en) * | 2009-03-13 | 2010-09-16 | Unibioscreen S.A. | Hellebrin and hellebrigenin derivatives |
NZ603261A (en) * | 2010-04-27 | 2014-12-24 | Pharma Mar Sa | Anticancer steroidal lactones unsaturated in position 7 (8) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1901484A1 (de) * | 1969-01-14 | 1970-10-29 | Hoechst Ag | Herzwirksame Oxyester von Steroid-Cardenoliden und -Bufandienoliden und Verfahren zu ihrer Herstellung |
-
1976
- 1976-12-17 GB GB52759/76A patent/GB1577633A/en not_active Expired
-
1977
- 1977-12-10 DE DE2755122A patent/DE2755122C2/de not_active Expired
- 1977-12-13 IT IT52184/77A patent/IT1113251B/it active
- 1977-12-15 FR FR7737795A patent/FR2374336A1/fr active Granted
- 1977-12-15 ZA ZA00777494A patent/ZA777494B/xx unknown
- 1977-12-15 SU SU772553849A patent/SU751328A3/ru active
- 1977-12-16 HU HU77DE947A patent/HU176767B/hu unknown
- 1977-12-16 ES ES465136A patent/ES465136A1/es not_active Expired
- 1977-12-16 BE BE6046270A patent/BE861968A/xx not_active IP Right Cessation
- 1977-12-16 JP JP52152295A patent/JPS591279B2/ja not_active Expired
- 1977-12-16 DD DD7700202719A patent/DD133151A5/xx unknown
- 1977-12-16 FI FI773814A patent/FI58135C/fi not_active IP Right Cessation
- 1977-12-16 AT AT0903877A patent/AT372391B/de not_active IP Right Cessation
- 1977-12-16 PL PL1977203030A patent/PL110178B1/pl not_active IP Right Cessation
- 1977-12-16 ES ES465135A patent/ES465135A1/es not_active Expired
-
1978
- 1978-01-01 CH CH1554377A patent/CH639107A5/de not_active IP Right Cessation
- 1978-12-25 SU SU782701599A patent/SU795487A3/ru active
Also Published As
Publication number | Publication date |
---|---|
SU795487A3 (ru) | 1981-01-07 |
FR2374336A1 (fr) | 1978-07-13 |
JPS591279B2 (ja) | 1984-01-11 |
FI773814A (fi) | 1978-06-18 |
FR2374336B1 (es) | 1980-11-07 |
ES465136A1 (es) | 1979-01-01 |
IT1113251B (it) | 1986-01-20 |
FI58135C (fi) | 1980-12-10 |
ZA777494B (en) | 1979-02-28 |
SU751328A3 (ru) | 1980-07-23 |
DE2755122A1 (de) | 1978-06-22 |
PL203030A1 (pl) | 1979-03-26 |
ATA903877A (de) | 1983-02-15 |
CH639107A5 (de) | 1983-10-31 |
PL110178B1 (en) | 1980-07-31 |
DD133151A5 (de) | 1978-12-13 |
DE2755122C2 (de) | 1983-06-30 |
JPS5395956A (en) | 1978-08-22 |
GB1577633A (en) | 1980-10-29 |
HU176767B (en) | 1981-05-28 |
FI58135B (fi) | 1980-08-29 |
AT372391B (de) | 1983-09-26 |
BE861968A (fr) | 1978-06-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19991220 |