FI57950C - Foerfarande foer framstaellning av saosom analgetika och sedativa anvaendbara trans-2,3,4,4a,5,9b-hexahydro-2-substituerad-1h-pyrido(4,3-b)indoler - Google Patents

Foerfarande foer framstaellning av saosom analgetika och sedativa anvaendbara trans-2,3,4,4a,5,9b-hexahydro-2-substituerad-1h-pyrido(4,3-b)indoler Download PDF

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Publication number
FI57950C
FI57950C FI3528/74A FI352874A FI57950C FI 57950 C FI57950 C FI 57950C FI 3528/74 A FI3528/74 A FI 3528/74A FI 352874 A FI352874 A FI 352874A FI 57950 C FI57950 C FI 57950C
Authority
FI
Finland
Prior art keywords
trans
pyrido
hexahydro
hydrogen
phenyl
Prior art date
Application number
FI3528/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI57950B (fi
FI352874A (es
Inventor
Joel Gilbert Berger
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of FI352874A publication Critical patent/FI352874A/fi
Publication of FI57950B publication Critical patent/FI57950B/fi
Application granted granted Critical
Publication of FI57950C publication Critical patent/FI57950C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
FI3528/74A 1973-12-06 1974-12-05 Foerfarande foer framstaellning av saosom analgetika och sedativa anvaendbara trans-2,3,4,4a,5,9b-hexahydro-2-substituerad-1h-pyrido(4,3-b)indoler FI57950C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42261373A 1973-12-06 1973-12-06
US42261373 1973-12-06
US52214574 1974-11-08
US05/522,145 US3991199A (en) 1973-12-06 1974-11-08 Pyridoindoles

Publications (3)

Publication Number Publication Date
FI352874A FI352874A (es) 1975-06-07
FI57950B FI57950B (fi) 1980-07-31
FI57950C true FI57950C (fi) 1980-11-10

Family

ID=27025674

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3528/74A FI57950C (fi) 1973-12-06 1974-12-05 Foerfarande foer framstaellning av saosom analgetika och sedativa anvaendbara trans-2,3,4,4a,5,9b-hexahydro-2-substituerad-1h-pyrido(4,3-b)indoler

Country Status (20)

Country Link
US (1) US3991199A (es)
JP (1) JPS50105697A (es)
AR (2) AR205452A1 (es)
AT (1) AT343117B (es)
CA (1) CA1021332A (es)
CH (1) CH612434A5 (es)
DD (1) DD117880A5 (es)
DE (1) DE2457305A1 (es)
DK (1) DK633874A (es)
ES (2) ES432646A1 (es)
FI (1) FI57950C (es)
FR (1) FR2253520B1 (es)
GB (1) GB1450002A (es)
IE (1) IE40328B1 (es)
IL (1) IL46193A (es)
LU (1) LU71428A1 (es)
NL (1) NL7415936A (es)
NO (1) NO744397L (es)
PH (1) PH11112A (es)
SU (1) SU592359A3 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7702300L (sv) * 1976-04-15 1977-10-16 Endo Lab Reduktionsforlopp
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
SE441448B (sv) * 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
US4252812A (en) * 1977-05-23 1981-02-24 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4267331A (en) * 1979-01-23 1981-05-12 Pfizer Inc. Process for the production of 2-substituted pyrido[4,3-b]-indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4252811A (en) * 1979-07-30 1981-02-24 Pfizer Inc. Hexahydro-trans-pyridoindole neuroleptic agents
US4431646A (en) * 1979-07-30 1984-02-14 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4352807A (en) * 1979-07-30 1982-10-05 Pfizer Inc. Hexahydro-trans-pyridoindole neuroleptic agents
US4431649A (en) * 1979-07-30 1984-02-14 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4432978A (en) * 1979-07-30 1984-02-21 Pfizer Inc. Hexahydro-trans-pyridoindole
US4427679A (en) 1981-01-16 1984-01-24 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
CS229067B1 (en) * 1981-08-20 1984-04-16 Svorad Stolc Medicinal preparation with antiarhythmic and supporting effect applied with hypoxia,and method of preparing active substance thereof
US5319087A (en) * 1987-04-16 1994-06-07 Eli Lilly And Company Piperidine opioid antagonists
US4992450A (en) * 1987-04-16 1991-02-12 Eli Lilly And Company Piperidine opioid antagonists
US4891379A (en) * 1987-04-16 1990-01-02 Kabushiki Kaisha Kobe Seikosho Piperidine opioid antagonists
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5159081A (en) * 1991-03-29 1992-10-27 Eli Lilly And Company Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
US5250542A (en) * 1991-03-29 1993-10-05 Eli Lilly And Company Peripherally selective piperidine carboxylate opioid antagonists
US5270328A (en) * 1991-03-29 1993-12-14 Eli Lilly And Company Peripherally selective piperidine opioid antagonists
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
TW470745B (en) * 1996-05-23 2002-01-01 Janssen Pharmaceutica Nv Hexahydro-pyrido[4,3-b]indole derivatives
FR2796644B1 (fr) * 1999-07-23 2001-09-07 Adir Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2283108C2 (ru) * 2003-12-08 2006-09-10 Сергей Олегович Бачурин ГЕРОПРОТЕКТОР НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
US20070179174A1 (en) * 2003-12-08 2007-08-02 Bachurin Sergei O Methods and compositions for slowing aging
WO2007032699A1 (fr) * 2005-09-12 2007-03-22 Avdulov, Nikolai Andreevich Isomeres optiques (+) et (-) de trans-2,3,4,4a,5,9b-hexahydro-2,8-dimethyl-1h-pirido[4,3-b]indole
EP1937263A2 (en) * 2005-10-04 2008-07-02 Medivation, Inc. Hydrogenated pyrido-indole compounds for the treatment of huntington ' s disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657254A (en) * 1969-10-31 1972-04-18 Nikolai Konstantinovich Barkov 3 6-dimethyl-1 2 3 4 4a 9a-hexahydro-gamma-carboline dihydrochloride
JPS541320B1 (es) * 1971-03-06 1979-01-23

Also Published As

Publication number Publication date
ATA970074A (de) 1977-09-15
FR2253520A1 (es) 1975-07-04
IL46193A (en) 1978-04-30
US3991199A (en) 1976-11-09
GB1450002A (en) 1976-09-22
LU71428A1 (es) 1975-06-11
FR2253520B1 (es) 1979-01-12
ES451600A1 (es) 1977-08-16
JPS50105697A (es) 1975-08-20
AT343117B (de) 1978-05-10
AR205452A1 (es) 1976-05-07
SU592359A3 (ru) 1978-02-05
IE40328B1 (en) 1979-05-09
FI57950B (fi) 1980-07-31
NO744397L (es) 1975-06-30
DD117880A5 (es) 1976-02-05
IE40328L (en) 1975-06-06
FI352874A (es) 1975-06-07
CA1021332A (en) 1977-11-22
NL7415936A (nl) 1975-06-10
PH11112A (en) 1977-10-27
DK633874A (es) 1975-07-28
ES432646A1 (es) 1977-04-16
IL46193A0 (en) 1975-03-13
DE2457305A1 (de) 1975-06-12
AU7607874A (en) 1976-06-10
CH612434A5 (es) 1979-07-31
AR205583A1 (es) 1976-05-14

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