ES451600A1 - Un metodo de preparacion de nuevos piridoindoles. - Google Patents

Un metodo de preparacion de nuevos piridoindoles.

Info

Publication number
ES451600A1
ES451600A1 ES451600A ES451600A ES451600A1 ES 451600 A1 ES451600 A1 ES 451600A1 ES 451600 A ES451600 A ES 451600A ES 451600 A ES451600 A ES 451600A ES 451600 A1 ES451600 A1 ES 451600A1
Authority
ES
Spain
Prior art keywords
reduction
useful
pyridoindoles
hypotensives
dealkylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES451600A
Other languages
English (en)
Inventor
Joel Gilbert Berger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENDO LAB
Original Assignee
ENDO LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ENDO LAB filed Critical ENDO LAB
Publication of ES451600A1 publication Critical patent/ES451600A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
ES451600A 1973-12-06 1976-09-16 Un metodo de preparacion de nuevos piridoindoles. Expired ES451600A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42261373A 1973-12-06 1973-12-06
US05/522,145 US3991199A (en) 1973-12-06 1974-11-08 Pyridoindoles

Publications (1)

Publication Number Publication Date
ES451600A1 true ES451600A1 (es) 1977-08-16

Family

ID=27025674

Family Applications (2)

Application Number Title Priority Date Filing Date
ES432646A Expired ES432646A1 (es) 1973-12-06 1974-12-05 Un metodo de preparacion de nuevos piridoindoles.
ES451600A Expired ES451600A1 (es) 1973-12-06 1976-09-16 Un metodo de preparacion de nuevos piridoindoles.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES432646A Expired ES432646A1 (es) 1973-12-06 1974-12-05 Un metodo de preparacion de nuevos piridoindoles.

Country Status (20)

Country Link
US (1) US3991199A (es)
JP (1) JPS50105697A (es)
AR (2) AR205452A1 (es)
AT (1) AT343117B (es)
CA (1) CA1021332A (es)
CH (1) CH612434A5 (es)
DD (1) DD117880A5 (es)
DE (1) DE2457305A1 (es)
DK (1) DK633874A (es)
ES (2) ES432646A1 (es)
FI (1) FI57950C (es)
FR (1) FR2253520B1 (es)
GB (1) GB1450002A (es)
IE (1) IE40328B1 (es)
IL (1) IL46193A (es)
LU (1) LU71428A1 (es)
NL (1) NL7415936A (es)
NO (1) NO744397L (es)
PH (1) PH11112A (es)
SU (1) SU592359A3 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7702300L (sv) * 1976-04-15 1977-10-16 Endo Lab Reduktionsforlopp
US4252812A (en) * 1977-05-23 1981-02-24 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
SE441448B (sv) * 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
US4267331A (en) * 1979-01-23 1981-05-12 Pfizer Inc. Process for the production of 2-substituted pyrido[4,3-b]-indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4432978A (en) * 1979-07-30 1984-02-21 Pfizer Inc. Hexahydro-trans-pyridoindole
US4431649A (en) * 1979-07-30 1984-02-14 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4431646A (en) * 1979-07-30 1984-02-14 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4252811A (en) * 1979-07-30 1981-02-24 Pfizer Inc. Hexahydro-trans-pyridoindole neuroleptic agents
US4352807A (en) * 1979-07-30 1982-10-05 Pfizer Inc. Hexahydro-trans-pyridoindole neuroleptic agents
US4427679A (en) 1981-01-16 1984-01-24 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
CS229067B1 (en) * 1981-08-20 1984-04-16 Svorad Stolc Medicinal preparation with antiarhythmic and supporting effect applied with hypoxia,and method of preparing active substance thereof
US5319087A (en) * 1987-04-16 1994-06-07 Eli Lilly And Company Piperidine opioid antagonists
US4891379A (en) * 1987-04-16 1990-01-02 Kabushiki Kaisha Kobe Seikosho Piperidine opioid antagonists
US4992450A (en) * 1987-04-16 1991-02-12 Eli Lilly And Company Piperidine opioid antagonists
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5250542A (en) * 1991-03-29 1993-10-05 Eli Lilly And Company Peripherally selective piperidine carboxylate opioid antagonists
US5270328A (en) * 1991-03-29 1993-12-14 Eli Lilly And Company Peripherally selective piperidine opioid antagonists
US5159081A (en) * 1991-03-29 1992-10-27 Eli Lilly And Company Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
TW470745B (en) * 1996-05-23 2002-01-01 Janssen Pharmaceutica Nv Hexahydro-pyrido[4,3-b]indole derivatives
FR2796644B1 (fr) * 1999-07-23 2001-09-07 Adir Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20070179174A1 (en) * 2003-12-08 2007-08-02 Bachurin Sergei O Methods and compositions for slowing aging
RU2283108C2 (ru) * 2003-12-08 2006-09-10 Сергей Олегович Бачурин ГЕРОПРОТЕКТОР НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
WO2007032699A1 (fr) * 2005-09-12 2007-03-22 Avdulov, Nikolai Andreevich Isomeres optiques (+) et (-) de trans-2,3,4,4a,5,9b-hexahydro-2,8-dimethyl-1h-pirido[4,3-b]indole
WO2007041697A2 (en) * 2005-10-04 2007-04-12 Medivation, Inc. Hydrogenated pyrido-indole compounds for the treatment of huntington ' s disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657254A (en) * 1969-10-31 1972-04-18 Nikolai Konstantinovich Barkov 3 6-dimethyl-1 2 3 4 4a 9a-hexahydro-gamma-carboline dihydrochloride
JPS541320B1 (es) * 1971-03-06 1979-01-23

Also Published As

Publication number Publication date
AR205583A1 (es) 1976-05-14
FI352874A (es) 1975-06-07
IL46193A0 (en) 1975-03-13
IL46193A (en) 1978-04-30
CH612434A5 (es) 1979-07-31
GB1450002A (en) 1976-09-22
AU7607874A (en) 1976-06-10
CA1021332A (en) 1977-11-22
LU71428A1 (es) 1975-06-11
AR205452A1 (es) 1976-05-07
FR2253520B1 (es) 1979-01-12
AT343117B (de) 1978-05-10
IE40328L (en) 1975-06-06
FR2253520A1 (es) 1975-07-04
NO744397L (es) 1975-06-30
ATA970074A (de) 1977-09-15
US3991199A (en) 1976-11-09
FI57950B (fi) 1980-07-31
ES432646A1 (es) 1977-04-16
NL7415936A (nl) 1975-06-10
PH11112A (en) 1977-10-27
IE40328B1 (en) 1979-05-09
SU592359A3 (ru) 1978-02-05
JPS50105697A (es) 1975-08-20
DE2457305A1 (de) 1975-06-12
DK633874A (es) 1975-07-28
DD117880A5 (es) 1976-02-05
FI57950C (fi) 1980-11-10

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