FI57749C - Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter - Google Patents

Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter Download PDF

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Publication number
FI57749C
FI57749C FI2349/74A FI234974A FI57749C FI 57749 C FI57749 C FI 57749C FI 2349/74 A FI2349/74 A FI 2349/74A FI 234974 A FI234974 A FI 234974A FI 57749 C FI57749 C FI 57749C
Authority
FI
Finland
Prior art keywords
pyridyl
formula
piperidyl
phenylalkyl
acid
Prior art date
Application number
FI2349/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI57749B (fi
FI234974A (de
Inventor
Adolf Langbein
Herbert Merz
Gerhard Walther
Klaus Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI234974A publication Critical patent/FI234974A/fi
Publication of FI57749B publication Critical patent/FI57749B/fi
Application granted granted Critical
Publication of FI57749C publication Critical patent/FI57749C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI2349/74A 1973-08-20 1974-08-07 Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter FI57749C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2341965A DE2341965C3 (de) 1973-08-20 1973-08-20 4- [N- (o-PyridyD- N-acyl] -aminolphenäthylpiperidine, Verfahren zu deren Herstellung sowie deren Verwendung bei der Bekämpfung von Schmerzzuständen
DE2341965 1973-08-20

Publications (3)

Publication Number Publication Date
FI234974A FI234974A (de) 1975-02-21
FI57749B FI57749B (fi) 1980-06-30
FI57749C true FI57749C (fi) 1980-10-10

Family

ID=5890196

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2349/74A FI57749C (fi) 1973-08-20 1974-08-07 Foerfarande foer framstaellning av analgetiska n-/1-(omega-fenylalkyl)-piperidyl-4/-n-(alfa-pyridyl)-karbonsyraamider och deras syraadditionssalter

Country Status (26)

Country Link
US (1) US3933832A (de)
JP (1) JPS5049285A (de)
AT (2) AT334901B (de)
BE (1) BE818989A (de)
BG (1) BG24669A3 (de)
CA (1) CA1041513A (de)
CH (2) CH603631A5 (de)
CS (2) CS182263B2 (de)
DD (1) DD114260A5 (de)
DE (1) DE2341965C3 (de)
DK (1) DK141097C (de)
ES (2) ES429234A1 (de)
FI (1) FI57749C (de)
FR (1) FR2241314B1 (de)
GB (1) GB1468283A (de)
HU (1) HU167563B (de)
IE (1) IE40511B1 (de)
IL (1) IL45494A (de)
NL (1) NL7410989A (de)
NO (1) NO140594C (de)
PH (1) PH11999A (de)
PL (2) PL91512B1 (de)
RO (2) RO63050A (de)
SE (1) SE402285B (de)
SU (2) SU504480A3 (de)
ZA (1) ZA745306B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191683A (en) * 1975-05-28 1980-03-04 Ciba-Geigy Corporation Derivatives of 4-aminopiperidine as stabilizers for polymers
US4225606A (en) * 1975-09-23 1980-09-30 Janssen Pharmaceutica N.V. N-Aryl-N-(1-L-4-piperidinyl)arylacetamides
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
USRE34201E (en) * 1989-04-20 1993-03-23 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
KR100849839B1 (ko) * 2001-02-23 2008-08-01 머크 앤드 캄파니 인코포레이티드 Ｎ-치환된 비-아릴-헤테로사이클릭 ｎｍｄａ/ｎｒ2ｂ 길항제 및 이를 포함하는 약제학적 조성물
US20060263401A1 (en) * 2001-07-13 2006-11-23 Flow Focusing, Inc. Formulation and Method for Preventing Infection
US20070254009A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic/bone morphogenic protein formulation and method of treatment
US20070254008A1 (en) * 2001-07-13 2007-11-01 Flow Focusing, Inc. Antibiotic formulation and method of treatment
US20040142013A1 (en) * 2001-07-13 2004-07-22 Flow Focusing, Inc. Implantable orthopedic surgical devices with controlled release antimicrobial component
US20030055075A1 (en) * 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
US7592360B2 (en) * 2003-06-04 2009-09-22 Merck & Co., Inc. 3-fluoro-piperidines as NMDA/NR2B antagonists
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
JO2642B1 (en) * 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
CA2682671C (en) * 2007-04-23 2015-11-17 Janssen Pharmaceutica N.V. Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists
AU2008240727C1 (en) * 2007-04-23 2013-10-03 Janssen Pharmaceutica N.V. Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists
CN101663292A (zh) * 2007-04-23 2010-03-03 詹森药业有限公司 作为快速解离的多巴胺2受体拮抗剂的4-烷氧基哒嗪衍生物
CN102159554B (zh) * 2008-07-03 2014-09-24 詹森药业有限公司 作为5-ht6受体拮抗剂的取代的6-(1-哌嗪基)-哒嗪
LT2307374T (lt) * 2008-07-31 2017-04-25 Janssen Pharmaceutica Nv Piperazin-1-il-trifluormetil-pakeistieji piridinai kaip greitai disocijuojantys dopamino 2 receptoriaus antagonistai

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1232147B (de) * 1961-04-13 1967-01-12 Bayer Ag Verfahren zur Herstellung von acylierten N-(Alkylaminoalkyl)-aminopyridinen
BE623427A (de) * 1961-10-10
US3141823A (en) * 1962-09-04 1964-07-21 Res Lab Dr C Janssen N V Method for producing analgesia
IL25840A (en) * 1965-07-24 1969-12-31 Bayer Ag Optically active pyridine derivatives and their production

Also Published As

Publication number Publication date
NO140594B (no) 1979-06-25
DK439974A (de) 1975-04-28
PL91562B1 (de) 1977-03-31
SU504480A3 (ru) 1976-02-25
IE40511B1 (en) 1979-06-20
DD114260A5 (de) 1975-07-20
ATA651274A (de) 1976-06-15
FR2241314A1 (de) 1975-03-21
GB1468283A (en) 1977-03-23
BE818989A (fr) 1975-02-19
NO140594C (no) 1979-10-03
ZA745306B (en) 1976-04-28
ATA651374A (de) 1976-06-15
RO63458A (fr) 1978-06-15
NL7410989A (nl) 1975-02-24
CS182263B2 (en) 1978-04-28
NO742970L (de) 1975-03-17
DE2341965A1 (de) 1975-03-06
SE402285B (sv) 1978-06-26
ES429234A1 (es) 1976-08-16
AU7248974A (en) 1976-02-19
RO63050A (de) 1978-05-15
SU507229A3 (ru) 1976-03-15
AT334900B (de) 1977-02-10
ES429221A1 (es) 1976-08-16
CS181767B2 (en) 1978-03-31
CA1041513A (en) 1978-10-31
IL45494A (en) 1977-07-31
HU167563B (de) 1975-11-28
PH11999A (en) 1978-10-06
IE40511L (en) 1975-02-20
DK141097C (da) 1980-08-18
DE2341965C3 (de) 1979-01-25
SE7410540L (de) 1975-02-21
FR2241314B1 (de) 1977-11-10
US3933832A (en) 1976-01-20
FI57749B (fi) 1980-06-30
DK141097B (da) 1980-01-14
CH603630A5 (de) 1978-08-31
JPS5049285A (de) 1975-05-01
FI234974A (de) 1975-02-21
IL45494A0 (en) 1974-11-29
DE2341965B2 (de) 1978-06-01
AT334901B (de) 1977-02-10
BG24669A3 (en) 1978-04-12
PL91512B1 (de) 1977-02-28
CH603631A5 (de) 1978-08-31

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