FI56698C - Foerfarande foer isolering och rening av mikrobiologiskt framstaellda aminosockerderivat - Google Patents

Foerfarande foer isolering och rening av mikrobiologiskt framstaellda aminosockerderivat Download PDF

Info

Publication number
FI56698C
FI56698C FI2740/74A FI274074A FI56698C FI 56698 C FI56698 C FI 56698C FI 2740/74 A FI2740/74 A FI 2740/74A FI 274074 A FI274074 A FI 274074A FI 56698 C FI56698 C FI 56698C
Authority
FI
Finland
Prior art keywords
glucose
acetone
amino sugar
solution
siy
Prior art date
Application number
FI2740/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI274074A (ja
FI56698B (fi
Inventor
Werner Frommer
Bodo Junge
Uwe Keup
Lutz Mueller
Walter Puls
Delf Schmidt
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI274074A publication Critical patent/FI274074A/fi
Priority to FI782283A priority Critical patent/FI58158C/fi
Application granted granted Critical
Publication of FI56698B publication Critical patent/FI56698B/fi
Publication of FI56698C publication Critical patent/FI56698C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
FI2740/74A 1973-09-22 1974-09-19 Foerfarande foer isolering och rening av mikrobiologiskt framstaellda aminosockerderivat FI56698C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI782283A FI58158C (fi) 1973-09-22 1978-07-19 Foerfarande foer separering och rengoering av mikrobiologiskt framstaellda aminosockerderivat

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2347782A DE2347782C3 (de) 1973-09-22 1973-09-22 Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
DE2347782 1973-09-22

Publications (3)

Publication Number Publication Date
FI274074A FI274074A (ja) 1975-03-23
FI56698B FI56698B (fi) 1979-11-30
FI56698C true FI56698C (fi) 1980-03-10

Family

ID=5893358

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2740/74A FI56698C (fi) 1973-09-22 1974-09-19 Foerfarande foer isolering och rening av mikrobiologiskt framstaellda aminosockerderivat

Country Status (28)

Country Link
JP (2) JPS5439474B2 (ja)
AR (1) AR210988A1 (ja)
AT (1) AT338199B (ja)
BE (1) BE820147A (ja)
BG (1) BG24959A3 (ja)
CA (1) CA1044164A (ja)
CH (1) CH596312A5 (ja)
CS (1) CS200173B2 (ja)
DD (1) DD117249A5 (ja)
DE (1) DE2347782C3 (ja)
DK (1) DK139979C (ja)
EG (1) EG12207A (ja)
ES (1) ES430283A1 (ja)
FI (1) FI56698C (ja)
FR (1) FR2244536B1 (ja)
GB (1) GB1482543A (ja)
HK (1) HK29780A (ja)
IE (1) IE39856B1 (ja)
IL (1) IL45685A (ja)
LU (2) LU88274I2 (ja)
NL (2) NL180941C (ja)
NO (1) NO142755C (ja)
PH (1) PH12530A (ja)
RO (1) RO84246B (ja)
SE (1) SE432111B (ja)
SU (1) SU562202A3 (ja)
YU (1) YU254574A (ja)
ZA (1) ZA745972B (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel
US4175123A (en) * 1976-12-23 1979-11-20 Bayer Aktiengesellschaft Amino-sugar derivatives, process for their preparation and pharmaceutical composition thereof
DE2719912C3 (de) * 1977-05-04 1979-12-06 Bayer Ag, 5090 Leverkusen Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen
JPS5953920B2 (ja) * 1977-12-28 1984-12-27 東洋醸造株式会社 新規なアミノ糖化合物およびその製法
GB2016497A (en) * 1978-02-10 1979-09-26 Taisho Pharmaceutical Co Ltd Microbiological production of amylase inhibitor
CA1121290A (en) * 1978-02-14 1982-04-06 Yasuji Suhara Amino sugar derivatives
DE3134591A1 (de) * 1981-09-01 1983-03-10 Bayer Ag, 5090 Leverkusen Neue arzneimittelpraeparationen fuer glykosidhydrolasen-inhibitoren
DE3543999A1 (de) * 1985-12-13 1987-06-19 Bayer Ag Hochreine acarbose
DE19507214A1 (de) * 1995-03-02 1996-10-31 Bayer Ag Acarbose-Biosynthesegene aus Actinoplanes sp., Verfahren zu ihrer Isolierung sowie ihre Verwendung
EP0796915A3 (de) * 1996-03-22 1999-04-14 Bayer Ag Verfahren zur Herstellung sowie zur Verwendung von Acarviosyl-Transferase bei der Umwandlung von Acarbose-Homologen in Acarbose, zur Herstellung von Acarbose-Homologen
DE19637591A1 (de) * 1996-09-13 1998-03-19 Bayer Ag Osmokontrolliertes Fermentationsverfahren zur Herstellung von Acarbose
IT1293819B1 (it) * 1997-08-05 1999-03-10 Univ Massachusetts Lowell Procedimento per la preparazione di acarbosio
DE19844924A1 (de) * 1998-09-30 2000-04-06 Bayer Ag Immobilisierte Zellen von Actinoplanes acarbosefaciens SE 50/110, Immobilisierungsverfahren und Verwendung des Immobilisats zur Herstellung von Acarbose
US7022684B2 (en) 2000-05-24 2006-04-04 Pfizer Inc. Treatment of rumen acidosis with α-amylase inhibitors
HRP20010792A2 (en) 2001-10-26 2003-04-30 Pliva D D Acarbose purification process
EP2145538A1 (de) 2008-07-15 2010-01-20 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Pflanzen- und Materialschutzmittel
TR201100150A2 (tr) 2011-01-06 2012-07-23 Bi̇lgi̇ç Mahmut Suda çözünür dozaj formları
TR201100148A2 (tr) 2011-01-06 2012-07-23 Bi̇lgi̇ç Mahmut Stabil akarboz förmülasyonları.
CN104144942A (zh) 2011-12-08 2014-11-12 拜耳知识产权有限责任公司 来自游动放线菌属菌种se50/110的新的放射菌整合和接合元件作为用于相关放线菌基因转化的质粒
WO2013115738A1 (en) 2012-01-31 2013-08-08 Mahmut Bilgic Micronized acarbose
EP2774619B1 (de) 2013-03-04 2016-05-18 BioActive Food GmbH Zusammensetzung zur Behandlung von hyperglykämischen Erkrankungen
EP2944311A1 (de) 2014-05-16 2015-11-18 BioActive Food GmbH Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen

Also Published As

Publication number Publication date
PH12530A (en) 1979-05-17
LU70953A1 (ja) 1975-05-28
ES430283A1 (es) 1976-12-16
EG12207A (en) 1979-03-31
DK497374A (ja) 1975-06-02
JPS5053593A (ja) 1975-05-12
IE39856L (en) 1975-03-22
AU7350374A (en) 1976-03-25
JPS5536479A (en) 1980-03-14
ATA757974A (de) 1976-12-15
DD117249A5 (ja) 1976-01-05
JPS5648518B2 (ja) 1981-11-16
HK29780A (en) 1980-06-06
FI274074A (ja) 1975-03-23
JPS5439474B2 (ja) 1979-11-28
DE2347782B2 (de) 1979-02-15
YU254574A (en) 1982-02-28
CS200173B2 (en) 1980-08-29
IE39856B1 (en) 1979-01-17
AR210988A1 (es) 1977-10-14
RO84246A (ro) 1984-05-23
ZA745972B (en) 1975-10-29
FR2244536B1 (ja) 1978-07-28
NL180941C (nl) 1987-05-18
NL930036I1 (nl) 1993-08-02
NL180941B (nl) 1986-12-16
BG24959A3 (en) 1978-06-15
FI56698B (fi) 1979-11-30
SE7411748L (ja) 1975-03-23
IL45685A0 (en) 1974-11-29
SU562202A3 (ru) 1977-06-15
SE432111B (sv) 1984-03-19
CH596312A5 (ja) 1978-03-15
NL930036I2 (nl) 1993-10-01
RO84246B (ro) 1984-07-30
NO142755B (no) 1980-06-30
GB1482543A (en) 1977-08-10
CA1044164A (en) 1978-12-12
DK139979B (da) 1979-05-28
NL7412478A (nl) 1975-03-25
NO743210L (ja) 1975-04-21
LU88274I2 (ja) 1994-02-03
AT338199B (de) 1977-08-10
BE820147A (fr) 1975-03-20
DK139979C (da) 1979-10-29
NO142755C (no) 1980-10-08
IL45685A (en) 1979-05-31
DE2347782C3 (de) 1979-10-11
DE2347782A1 (de) 1975-04-10
FR2244536A1 (ja) 1975-04-18

Similar Documents

Publication Publication Date Title
FI56698C (fi) Foerfarande foer isolering och rening av mikrobiologiskt framstaellda aminosockerderivat
US4062950A (en) Amino sugar derivatives
FI63062C (fi) Foerfarande foer framstaellning av de farmaceutiskt aktiva aminosockerderivaten trestatin a trestatin b och trestatin c
Kim et al. α‐Glucosidase inhibitory activity of bromophenol purified from the red alga Polyopes lancifolia
Kim et al. Potent α-glucosidase inhibitors purified from the red alga Grateloupia elliptica
MIMAKI et al. Steroidal saponins from the underground parts of Hosta longipes and their inhibitory activity on tumor promoter-induced phospholipid metabolism
JPS63196596A (ja) 末端にイノシト−ル残基を結合したグルコオリゴ糖およびその製造方法
JPH0566394B2 (ja)
WO1997023637A1 (en) Galactopyranosides and their use
US4029883A (en) Dehydroxylation of aminosugars
JPH02117676A (ja) Bu―3420t抗腫瘍性抗生物質
Terayama et al. Synthesis of a New Allosamidin Analog, N, N′-Diacetyl-β-Chitobiosyl Allosamizoline, and Its Inhibitory Activity against Some Chitinases
Křen Enzymatic and chemical glycosylations of ergot alkaloids and biological aspects of new compounds
KR900008247B1 (ko) 새로운 생리활성물질 아르파메닌(Arphamenine)의 제조방법
KR920001448B1 (ko) Bbm-2478 항생제 착화합물
FI58158B (fi) Foerfarande foer separering och rengoering av mikrobiologiskt framstaellda aminosockerderivat
FI63964C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara aminosockerderivat
Ogata et al. Substrate specificity of N-acetylhexosaminidase from Aspergillus oryzae to artificial glycosyl acceptors having various substituents at the reducing ends
US4990500A (en) Oxirane pseudooligosaccharides, a process for their preparation, their use and pharmaceutical preparations
KR790001709B1 (ko) 아미노-슈가 화합물의 제조방법
EP4349843A1 (en) Alpha-salidroside, and preparation method therefor and application thereof
JP3687929B2 (ja) 新規化合物a−76202及びその製造法
HU194314B (en) Process for preparing new, alpha-glucosidase inhibiting pseudooligosaccharides
EP0311054B1 (en) Anthracycline Antibiotics
JPH0319239B2 (ja)