IE39856L - Aminosugars - Google Patents
AminosugarsInfo
- Publication number
- IE39856L IE39856L IE741946A IE194674A IE39856L IE 39856 L IE39856 L IE 39856L IE 741946 A IE741946 A IE 741946A IE 194674 A IE194674 A IE 194674A IE 39856 L IE39856 L IE 39856L
- Authority
- IE
- Ireland
- Prior art keywords
- alpha
- glucose units
- bisdesoxy
- glycopyranosyl
- pyranosyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Enzymes And Modification Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
New amino sugar derivatives of the formula wherein R is a glucose unit or an oligosaccharide chain of 2 to 7 glucose units glycosidically linked .alpha.-1:4 inhibit glycoside-hydrolases of the digestive tract. A representative embodiment is O-{4,5-bisdesoxy-4-{1 S-¢1,4,6/5)-4,5,6-tri-hydroxy-3-hydroxymethylcyclohex-2-en-1-ylamino!-.alpha.-D-gluco-pyranosyl}-(1?4)-O-.alpha.-D-glucopyranosyl-(1?4)-O-.alpha.-D-gluco-pyranosyl-(1?4)-D-glycopyranose. (R = 3 glucose units). In addition to this series of compounds, an isomeric series of amino sugars for compounds having three or more glucose units are simultaneously produced by Actinoplanacetes. The isomeric material having three glucose units is O-{4,6-bisdesoxy-4-{1 S-¢1,4,6/5)-4,5,6-dihydroxy-3-hydroxy-methyl-4-O-.alpha.-D-glycopyranosyl-(1?4)-cyclohex-2-en-1-ylamino!-.alpha.-D-glycopyranosyl}-(1?4)-O-.alpha.-D-glucopyranosyl-(1?4)-D-glucopyranose.
[CA1044164A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2347782A DE2347782C3 (en) | 1973-09-22 | 1973-09-22 | Amino sugar derivatives, processes for their preparation and medicaments containing these compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39856L true IE39856L (en) | 1975-03-22 |
| IE39856B1 IE39856B1 (en) | 1979-01-17 |
Family
ID=5893358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1946/74A IE39856B1 (en) | 1973-09-22 | 1974-09-20 | New amino-sugar compounds their production and their medicinal use |
Country Status (28)
| Country | Link |
|---|---|
| JP (2) | JPS5439474B2 (en) |
| AR (1) | AR210988A1 (en) |
| AT (1) | AT338199B (en) |
| BE (1) | BE820147A (en) |
| BG (1) | BG24959A3 (en) |
| CA (1) | CA1044164A (en) |
| CH (1) | CH596312A5 (en) |
| CS (1) | CS200173B2 (en) |
| DD (1) | DD117249A5 (en) |
| DE (1) | DE2347782C3 (en) |
| DK (1) | DK139979C (en) |
| EG (1) | EG12207A (en) |
| ES (1) | ES430283A1 (en) |
| FI (1) | FI56698C (en) |
| FR (1) | FR2244536B1 (en) |
| GB (1) | GB1482543A (en) |
| HK (1) | HK29780A (en) |
| IE (1) | IE39856B1 (en) |
| IL (1) | IL45685A (en) |
| LU (2) | LU88274I2 (en) |
| NL (2) | NL180941C (en) |
| NO (1) | NO142755C (en) |
| PH (1) | PH12530A (en) |
| RO (1) | RO84246B (en) |
| SE (1) | SE432111B (en) |
| SU (1) | SU562202A3 (en) |
| YU (1) | YU254574A (en) |
| ZA (1) | ZA745972B (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2614393C3 (en) * | 1976-04-02 | 1980-04-03 | Bayer Ag, 5090 Leverkusen | Amino sugar derivatives and medicaments containing these compounds |
| US4175123A (en) * | 1976-12-23 | 1979-11-20 | Bayer Aktiengesellschaft | Amino-sugar derivatives, process for their preparation and pharmaceutical composition thereof |
| DE2719912C3 (en) * | 1977-05-04 | 1979-12-06 | Bayer Ag, 5090 Leverkusen | Process for the isolation of 0- | 4,6-dideoxy-4- [JJl SO, 4,6 / 5) -4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a - D-glucopyranosyl} - (I right arrow 4) -0- a D-glucopyranosyl- (l right arrow 4) -D-glucopyranose from culture broths |
| JPS5953920B2 (en) * | 1977-12-28 | 1984-12-27 | 東洋醸造株式会社 | Novel amino sugar compound and its production method |
| GB2016497A (en) * | 1978-02-10 | 1979-09-26 | Taisho Pharmaceutical Co Ltd | Microbiological production of amylase inhibitor |
| CA1121290A (en) * | 1978-02-14 | 1982-04-06 | Yasuji Suhara | Amino sugar derivatives |
| DE3134591A1 (en) * | 1981-09-01 | 1983-03-10 | Bayer Ag, 5090 Leverkusen | NEW MEDICINE PREPARATIONS FOR GLYCOSIDE HYDROLASE INHIBITORS |
| DE3543999A1 (en) * | 1985-12-13 | 1987-06-19 | Bayer Ag | HIGH PURITY ACARBOSE |
| DE19507214A1 (en) * | 1995-03-02 | 1996-10-31 | Bayer Ag | Acarbose biosynthesis genes from Actinoplanes sp., Process for their isolation and their use |
| EP0796915A3 (en) * | 1996-03-22 | 1999-04-14 | Bayer Ag | Process for the preparation and use of acarviosyl-transferase in the conversion of ascarbose-homologous in acarbose and in the preparation of acarbose-homologous |
| DE19637591A1 (en) * | 1996-09-13 | 1998-03-19 | Bayer Ag | Osmocontrolled fermentation process for the production of acarbose |
| IT1293819B1 (en) * | 1997-08-05 | 1999-03-10 | Univ Massachusetts Lowell | PROCEDURE FOR THE PREPARATION OF ACARBOSE |
| DE19844924A1 (en) * | 1998-09-30 | 2000-04-06 | Bayer Ag | Immobilized cells of Actinoplanes acarbosefaciens SE 50/110, immobilization method and use of the immobilizate for the production of acarbose |
| US7022684B2 (en) | 2000-05-24 | 2006-04-04 | Pfizer Inc. | Treatment of rumen acidosis with α-amylase inhibitors |
| HRP20010792A2 (en) | 2001-10-26 | 2003-04-30 | Pliva D D | Acarbose purification process |
| EP2145538A1 (en) | 2008-07-15 | 2010-01-20 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts | Plant and material preservative |
| TR201100150A2 (en) | 2011-01-06 | 2012-07-23 | Bi̇lgi̇ç Mahmut | Water soluble dosage forms |
| TR201100148A2 (en) | 2011-01-06 | 2012-07-23 | Bi̇lgi̇ç Mahmut | Stable acarbose formulations. |
| IN2014CN04155A (en) | 2011-12-08 | 2015-07-17 | Bayer Ip Gmbh | |
| WO2013115738A1 (en) | 2012-01-31 | 2013-08-08 | Mahmut Bilgic | Micronized acarbose |
| EP2774619B1 (en) | 2013-03-04 | 2016-05-18 | BioActive Food GmbH | Composition for the treatment of hyperglycaemic diseases |
| EP2944311A1 (en) | 2014-05-16 | 2015-11-18 | BioActive Food GmbH | Combination of biologically active substances for treating hyperglycemic diseases |
-
1973
- 1973-09-22 DE DE2347782A patent/DE2347782C3/en not_active Expired
-
1974
- 1974-09-06 NO NO74743210A patent/NO142755C/en unknown
- 1974-09-16 PH PH16285A patent/PH12530A/en unknown
- 1974-09-18 CA CA209,484A patent/CA1044164A/en not_active Expired
- 1974-09-18 CH CH1264974A patent/CH596312A5/xx not_active IP Right Cessation
- 1974-09-18 SE SE7411748A patent/SE432111B/en active Protection Beyond IP Right Term
- 1974-09-18 BG BG7400027718A patent/BG24959A3/en unknown
- 1974-09-19 AR AR255651A patent/AR210988A1/en active
- 1974-09-19 YU YU02545/74A patent/YU254574A/en unknown
- 1974-09-19 JP JP10721674A patent/JPS5439474B2/ja not_active Expired
- 1974-09-19 FI FI2740/74A patent/FI56698C/en active
- 1974-09-20 GB GB41073/74A patent/GB1482543A/en not_active Expired
- 1974-09-20 FR FR7431906A patent/FR2244536B1/fr not_active Expired
- 1974-09-20 AT AT757974A patent/AT338199B/en active Protection Beyond IP Right Term
- 1974-09-20 SU SU2063266A patent/SU562202A3/en active
- 1974-09-20 DK DK497374A patent/DK139979C/en active
- 1974-09-20 NL NLAANVRAGE7412478,A patent/NL180941C/en not_active IP Right Cessation
- 1974-09-20 BE BE148729A patent/BE820147A/en not_active IP Right Cessation
- 1974-09-20 IL IL7445685A patent/IL45685A/en unknown
- 1974-09-20 IE IE1946/74A patent/IE39856B1/en unknown
- 1974-09-20 CS CS746498A patent/CS200173B2/en unknown
- 1974-09-20 ZA ZA00745972A patent/ZA745972B/en unknown
- 1974-09-20 DD DD181235A patent/DD117249A5/xx unknown
- 1974-09-20 LU LU88274C patent/LU88274I2/xx unknown
- 1974-09-20 LU LU70953A patent/LU70953A1/xx active Protection Beyond IP Right Term
- 1974-09-21 ES ES430283A patent/ES430283A1/en not_active Expired
- 1974-09-21 EG EG411/74A patent/EG12207A/en active
- 1974-09-21 RO RO80038A patent/RO84246B/en unknown
-
1979
- 1979-07-20 JP JP9174679A patent/JPS5536479A/en active Granted
-
1980
- 1980-05-29 HK HK297/80A patent/HK29780A/en unknown
-
1993
- 1993-05-24 NL NL930036C patent/NL930036I2/en unknown
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