FI118204B - Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet - Google Patents

Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet Download PDF

Info

Publication number
FI118204B
FI118204B FI964285A FI964285A FI118204B FI 118204 B FI118204 B FI 118204B FI 964285 A FI964285 A FI 964285A FI 964285 A FI964285 A FI 964285A FI 118204 B FI118204 B FI 118204B
Authority
FI
Finland
Prior art keywords
pharmaceutical preparation
radical
preparation according
phospholipids
docetaxel
Prior art date
Application number
FI964285A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI964285A (fi
FI964285A0 (fi
Inventor
Armin Wendel
Manfred Durr
Joerg-Christian Hager
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of FI964285A publication Critical patent/FI964285A/fi
Publication of FI964285A0 publication Critical patent/FI964285A0/fi
Application granted granted Critical
Publication of FI118204B publication Critical patent/FI118204B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
FI964285A 1994-04-25 1996-10-24 Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet FI118204B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9404951 1994-04-25
FR9404951A FR2718963B1 (fr) 1994-04-25 1994-04-25 Nouvelle composition pharmaceutique à base de taxoïdes.
PCT/FR1995/000532 WO1995028923A1 (fr) 1994-04-25 1995-04-24 Compositions pharmaceutiques a base de derives de la classe des taxanes
FR9500532 1995-04-24

Publications (3)

Publication Number Publication Date
FI964285A FI964285A (fi) 1996-10-24
FI964285A0 FI964285A0 (fi) 1996-10-24
FI118204B true FI118204B (fi) 2007-08-31

Family

ID=9462475

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964285A FI118204B (fi) 1994-04-25 1996-10-24 Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet

Country Status (26)

Country Link
US (1) US5670536A (cs)
EP (1) EP0758231B1 (cs)
JP (1) JP3950993B2 (cs)
KR (1) KR100401119B1 (cs)
CN (1) CN1283243C (cs)
AT (1) ATE202931T1 (cs)
AU (1) AU691283B2 (cs)
BR (1) BR9507846A (cs)
CZ (1) CZ285720B6 (cs)
DE (1) DE69521693T2 (cs)
DK (1) DK0758231T3 (cs)
ES (1) ES2160163T3 (cs)
FI (1) FI118204B (cs)
FR (1) FR2718963B1 (cs)
GE (1) GEP20002069B (cs)
GR (1) GR3036211T3 (cs)
HU (1) HU225971B1 (cs)
NO (1) NO314745B1 (cs)
NZ (1) NZ285122A (cs)
PL (1) PL179623B1 (cs)
PT (1) PT758231E (cs)
RU (1) RU2157200C2 (cs)
SK (1) SK283255B6 (cs)
TW (1) TW416849B (cs)
WO (1) WO1995028923A1 (cs)
ZA (1) ZA953358B (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6096331A (en) * 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US6395770B1 (en) * 1995-10-26 2002-05-28 Baker Norton Pharmaceuticals, Inc. Method and compositions for administering taxanes orally to human patients
US6245805B1 (en) 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
KR100789008B1 (ko) * 1997-06-27 2007-12-26 아브락시스 바이오사이언스 인크. 신규 약물 제제
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
BR9907647B1 (pt) * 1998-02-05 2014-04-01 Novartis Ag Novartis S A Novartis Inc Formulação farmacêutica na forma de um concentrado para infusão, o qual deve ser diluído antes da administração, e solução para infusão
US6071952A (en) * 1998-12-02 2000-06-06 Mylan Pharmaceuticals, Inc. Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
DE10255285A1 (de) * 2002-11-26 2004-06-03 Mcs Micro Carrier Systems Gmbh Selbst formende Phospholipid-Gele
US20050152979A1 (en) * 2003-09-05 2005-07-14 Cell Therapeutics, Inc. Hydrophobic drug compositions containing reconstitution enhancer
US8557861B2 (en) * 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
TWI376239B (en) * 2006-02-01 2012-11-11 Andrew Xian Chen Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
CA2683712A1 (en) * 2007-04-20 2009-01-15 Sun Pharmaceutical Industries Limited Pharmaceutical compositions
EP1987813A1 (en) * 2007-05-04 2008-11-05 Pharmatex Italia Srl Injectable pharmaceutical formulation of taxoids in stable liposomes
EP2205215A2 (en) * 2007-10-01 2010-07-14 Intas Pharmaceuticals Limited Docetaxel injectable composition, being absolutely free of ethanol
WO2009061458A1 (en) * 2007-11-07 2009-05-14 Amfit, Inc. Impression foam digital scanner
ES2344674B1 (es) * 2008-08-07 2011-06-29 Gp Pharm, S.A. Composicion farmaceutica inyectable de taxanos.
US8541360B2 (en) * 2008-11-19 2013-09-24 Ben Venue Laboratories, Inc. Parenteral formulations comprising sugar-based esters and ethers
WO2012156999A1 (en) * 2011-05-19 2012-11-22 Manu Chaudhary Ready to use docetaxel formulation
EP2875814B1 (en) 2012-07-19 2018-08-22 FUJIFILM Corporation Liquid composition containing taxane-based active ingredient, process for producing same, and liquid medicinal preparation
EA022182B1 (ru) * 2012-12-24 2015-11-30 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы доцетаксела

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4507217A (en) * 1983-03-07 1985-03-26 Lipid Specialties, Inc. Magnetic compositions and magnetic memory devices prepared therefrom
US5411947A (en) * 1989-06-28 1995-05-02 Vestar, Inc. Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
DK0706373T3 (da) * 1992-03-23 2000-09-18 Univ Georgetown Liposomindkapslet taxol og en fremgangsmåde til anvendelse heraf
WO1994026254A1 (en) * 1993-05-17 1994-11-24 The Liposome Company, Inc. Incorporation of taxol into liposomes and gels
WO1994026253A1 (en) * 1993-05-19 1994-11-24 The Liposome Company, Inc. Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation

Also Published As

Publication number Publication date
WO1995028923A1 (fr) 1995-11-02
SK135696A3 (en) 1997-05-07
CZ309396A3 (en) 1997-01-15
KR100401119B1 (ko) 2004-03-19
TW416849B (en) 2001-01-01
NO964433D0 (no) 1996-10-18
DK0758231T3 (da) 2001-09-24
RU2157200C2 (ru) 2000-10-10
NO314745B1 (no) 2003-05-19
ZA953358B (en) 1996-01-17
DE69521693T2 (de) 2002-05-02
GEP20002069B (en) 2000-05-10
NO964433L (no) 1996-10-18
AU691283B2 (en) 1998-05-14
JPH09512261A (ja) 1997-12-09
DE69521693D1 (de) 2001-08-16
CZ285720B6 (cs) 1999-10-13
PL316942A1 (en) 1997-02-17
BR9507846A (pt) 1997-09-16
HU9602942D0 (en) 1996-12-30
SK283255B6 (sk) 2003-04-01
EP0758231A1 (fr) 1997-02-19
FR2718963A1 (fr) 1995-10-27
HU225971B1 (en) 2008-01-28
ATE202931T1 (de) 2001-07-15
US5670536A (en) 1997-09-23
FI964285A (fi) 1996-10-24
GR3036211T3 (en) 2001-10-31
NZ285122A (en) 1998-06-26
PT758231E (pt) 2001-11-30
FR2718963B1 (fr) 1996-05-24
PL179623B1 (pl) 2000-10-31
CN1146722A (zh) 1997-04-02
CN1283243C (zh) 2006-11-08
AU2412695A (en) 1995-11-16
FI964285A0 (fi) 1996-10-24
ES2160163T3 (es) 2001-11-01
KR970702033A (ko) 1997-05-13
HUT75513A (en) 1997-05-28
JP3950993B2 (ja) 2007-08-01
EP0758231B1 (fr) 2001-07-11

Similar Documents

Publication Publication Date Title
FI118204B (fi) Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet
KR0136722B1 (ko) 택산류 유도체를 기재로한 신규한 조성물
EP2054036B1 (en) Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
TW200522978A (en) Tocopherol-modified therapeutic drug compounds
WO2001025223A1 (en) Stabilization of taxane-containing dispersed systems
EP1694660B1 (en) Process for the preparation of anhydrous and hydrated active pharmaceutical ingredients (apis); stable pharmaceutical compositions prepared from the same and uses of said compositions
BRPI0821740B1 (pt) sistema i de liberação de droga
TW422706B (en) An oil-in-water emulsion type of paclitaxel
CA2701789A1 (fr) Nouvelles compositions a base de taxoides
JP2019500406A (ja) 抗癌薬の新規ナノ製剤及びその製造方法
CN105380906A (zh) 一种卡巴他赛肿瘤靶向脂质体注射剂及其制备方法
FR2715846A1 (fr) Nouvelle composition pharmceutique à base de taxoïdes.
US20070032438A1 (en) Pharmaceutical compositions containing taxanes and methods for preparing the pharmaceutical compositions
CA2188599C (fr) Compositions pharmaceutiques a base de derives de la classe des taxanes
SK287850B6 (sk) Stable pharmaceutical form of the anti-cancer drug
CN101081219A (zh) 一种含紫杉烷类化合物的组合物、其制备方法和用途
GB2285804A (en) Terpinol esters & their use as biotenside solvents for pharmaceuticals and cosmetics
WO2013026989A2 (fr) Liposome comprenant au moins un derive de cholesterol
US20050129719A1 (en) Concentrated emulsion formulation for silatecan
MXPA00004456A (en) Pharmaceutical compositions containing cyclodextrins and taxoids

Legal Events

Date Code Title Description
FG Patent granted

Ref document number: 118204

Country of ref document: FI

MM Patent lapsed