DE69521693T2 - Taxanderivate enthaltende arzneizubereitungen - Google Patents

Taxanderivate enthaltende arzneizubereitungen

Info

Publication number
DE69521693T2
DE69521693T2 DE69521693T DE69521693T DE69521693T2 DE 69521693 T2 DE69521693 T2 DE 69521693T2 DE 69521693 T DE69521693 T DE 69521693T DE 69521693 T DE69521693 T DE 69521693T DE 69521693 T2 DE69521693 T2 DE 69521693T2
Authority
DE
Germany
Prior art keywords
taxa
derivatives
preparations containing
medicinal preparations
docetaxel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69521693T
Other languages
English (en)
Other versions
DE69521693D1 (de
Inventor
Manfred Durr
Joerg-Christian Hager
Armin Wendel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE69521693D1 publication Critical patent/DE69521693D1/de
Application granted granted Critical
Publication of DE69521693T2 publication Critical patent/DE69521693T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE69521693T 1994-04-25 1995-04-24 Taxanderivate enthaltende arzneizubereitungen Expired - Lifetime DE69521693T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404951A FR2718963B1 (fr) 1994-04-25 1994-04-25 Nouvelle composition pharmaceutique à base de taxoïdes.
PCT/FR1995/000532 WO1995028923A1 (fr) 1994-04-25 1995-04-24 Compositions pharmaceutiques a base de derives de la classe des taxanes

Publications (2)

Publication Number Publication Date
DE69521693D1 DE69521693D1 (de) 2001-08-16
DE69521693T2 true DE69521693T2 (de) 2002-05-02

Family

ID=9462475

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69521693T Expired - Lifetime DE69521693T2 (de) 1994-04-25 1995-04-24 Taxanderivate enthaltende arzneizubereitungen

Country Status (26)

Country Link
US (1) US5670536A (de)
EP (1) EP0758231B1 (de)
JP (1) JP3950993B2 (de)
KR (1) KR100401119B1 (de)
CN (1) CN1283243C (de)
AT (1) ATE202931T1 (de)
AU (1) AU691283B2 (de)
BR (1) BR9507846A (de)
CZ (1) CZ285720B6 (de)
DE (1) DE69521693T2 (de)
DK (1) DK0758231T3 (de)
ES (1) ES2160163T3 (de)
FI (1) FI118204B (de)
FR (1) FR2718963B1 (de)
GE (1) GEP20002069B (de)
GR (1) GR3036211T3 (de)
HU (1) HU225971B1 (de)
NO (1) NO314745B1 (de)
NZ (1) NZ285122A (de)
PL (1) PL179623B1 (de)
PT (1) PT758231E (de)
RU (1) RU2157200C2 (de)
SK (1) SK283255B6 (de)
TW (1) TW416849B (de)
WO (1) WO1995028923A1 (de)
ZA (1) ZA953358B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6096331A (en) * 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US6395770B1 (en) * 1995-10-26 2002-05-28 Baker Norton Pharmaceuticals, Inc. Method and compositions for administering taxanes orally to human patients
US6245805B1 (en) * 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
CN100462066C (zh) * 1997-06-27 2009-02-18 美国生物科学有限公司 药剂的新制剂及其制备和应用方法
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
CA2320182C (en) * 1998-02-05 2008-11-25 Novartis Ag Compositions containing organic compounds
US6071952A (en) * 1998-12-02 2000-06-06 Mylan Pharmaceuticals, Inc. Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
DE10255285A1 (de) * 2002-11-26 2004-06-03 Mcs Micro Carrier Systems Gmbh Selbst formende Phospholipid-Gele
US20050152979A1 (en) * 2003-09-05 2005-07-14 Cell Therapeutics, Inc. Hydrophobic drug compositions containing reconstitution enhancer
US8557861B2 (en) * 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
TWI376239B (en) * 2006-02-01 2012-11-11 Andrew Xian Chen Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
EP2146695A4 (de) * 2007-04-23 2010-05-19 Sun Pharmaceuticals Ind Ltd Pharmazeutische zusammensetzungen
EP1987813A1 (de) * 2007-05-04 2008-11-05 Pharmatex Italia Srl Injizierbare pharmazeutische Formulierung aus Taxoiden in stabilen Liposomen
EP2205215A2 (de) * 2007-10-01 2010-07-14 Intas Pharmaceuticals Limited Absolut ethanolfreie injizierbare docetaxelzusammensetzung
WO2009061458A1 (en) * 2007-11-07 2009-05-14 Amfit, Inc. Impression foam digital scanner
ES2344674B1 (es) * 2008-08-07 2011-06-29 Gp Pharm, S.A. Composicion farmaceutica inyectable de taxanos.
US8541360B2 (en) * 2008-11-19 2013-09-24 Ben Venue Laboratories, Inc. Parenteral formulations comprising sugar-based esters and ethers
WO2012156999A1 (en) * 2011-05-19 2012-11-22 Manu Chaudhary Ready to use docetaxel formulation
EP2875814B1 (de) 2012-07-19 2018-08-22 FUJIFILM Corporation Flüssige zusammensetzung mit wirkstoff auf taxanbasis, verfahren zur herstellung davon und flüssiges arzneimittel
EA022182B1 (ru) * 2012-12-24 2015-11-30 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы доцетаксела

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4507217A (en) * 1983-03-07 1985-03-26 Lipid Specialties, Inc. Magnetic compositions and magnetic memory devices prepared therefrom
US5411947A (en) * 1989-06-28 1995-05-02 Vestar, Inc. Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
WO1993018751A1 (en) * 1992-03-23 1993-09-30 Georgetown University Liposome encapsulated taxol and a method of using the same
AU6833994A (en) * 1993-05-17 1994-12-12 Liposome Company, Inc., The Incorporation of taxol into liposomes and gels
WO1994026253A1 (en) * 1993-05-19 1994-11-24 The Liposome Company, Inc. Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation

Also Published As

Publication number Publication date
PT758231E (pt) 2001-11-30
NO314745B1 (no) 2003-05-19
CZ309396A3 (en) 1997-01-15
RU2157200C2 (ru) 2000-10-10
NO964433L (no) 1996-10-18
EP0758231A1 (de) 1997-02-19
CN1146722A (zh) 1997-04-02
DK0758231T3 (da) 2001-09-24
DE69521693D1 (de) 2001-08-16
US5670536A (en) 1997-09-23
PL316942A1 (en) 1997-02-17
ES2160163T3 (es) 2001-11-01
HU9602942D0 (en) 1996-12-30
FR2718963A1 (fr) 1995-10-27
WO1995028923A1 (fr) 1995-11-02
GR3036211T3 (en) 2001-10-31
JP3950993B2 (ja) 2007-08-01
NO964433D0 (no) 1996-10-18
FI964285A (fi) 1996-10-24
HUT75513A (en) 1997-05-28
BR9507846A (pt) 1997-09-16
AU2412695A (en) 1995-11-16
HU225971B1 (en) 2008-01-28
ATE202931T1 (de) 2001-07-15
KR970702033A (ko) 1997-05-13
KR100401119B1 (ko) 2004-03-19
TW416849B (en) 2001-01-01
FI118204B (fi) 2007-08-31
CZ285720B6 (cs) 1999-10-13
EP0758231B1 (de) 2001-07-11
GEP20002069B (en) 2000-05-10
FI964285A0 (fi) 1996-10-24
PL179623B1 (pl) 2000-10-31
NZ285122A (en) 1998-06-26
FR2718963B1 (fr) 1996-05-24
SK283255B6 (sk) 2003-04-01
JPH09512261A (ja) 1997-12-09
ZA953358B (en) 1996-01-17
AU691283B2 (en) 1998-05-14
SK135696A3 (en) 1997-05-07
CN1283243C (zh) 2006-11-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC