FI117123B - Farmaceutisk komposition för oral administration av flavonoider - Google Patents
Farmaceutisk komposition för oral administration av flavonoider Download PDFInfo
- Publication number
- FI117123B FI117123B FI955310A FI955310A FI117123B FI 117123 B FI117123 B FI 117123B FI 955310 A FI955310 A FI 955310A FI 955310 A FI955310 A FI 955310A FI 117123 B FI117123 B FI 117123B
- Authority
- FI
- Finland
- Prior art keywords
- diosmin
- pharmaceutical composition
- composition according
- flavonoids
- oral administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
Claims (6)
1. Farmaceutisk sammansättning för att oralt admir 5 flavonoider och speciellt diosmin extraherade ur E kannetecknad därav, att sammansättningen är en ski granul i form av tablett eller portionspäse, som j ler mikroniserad diosmin.
2. Farmaceutisk sammansättning enligt patentkravet kanne tecknad därav, att diosmin i sin mikroniserac har ett partikelstorlek av 0,1 - 10 pm.
3. Farmaceutisk sammansättning enligt patentkravet 15 netecknad därav, att granulen gjorts skummande ger använda karboxylsyra och en eller flera karbonater
4. Farmaceutisk sammansättning enligt patentkravet kännetecknad därav, att den skummande granulen inn 20 sötningsmedel, smaksättning och farmaceutiskt godt fyllmedel. Ml
*·.·* 5. Farmaceutisk sammansättning enligt patentkravet * kännetecknad därav, att den innehäller 0,1 - 5 g m «· · * 25 roniserad diosmin. • · « · · «It «Μ
♦ • :*: 6. Förfarande för framställning av en farmaceutisk ··* » sättning enligt patentkravet 1, kannetecknat därav * förfarandet är ett enfasigt granuleringsförfarande e 30 det i diosmin ingäende vattnet päbörjar granulerin * i t · *
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9413336A FR2726469B1 (fr) | 1994-11-08 | 1994-11-08 | Composition pharmaceutique pour l'administration orale de flavonoides |
FR9413336 | 1994-11-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI955310A0 FI955310A0 (sv) | 1995-11-06 |
FI955310A FI955310A (sv) | 1996-05-09 |
FI117123B true FI117123B (sv) | 2006-06-30 |
Family
ID=9468588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI955310A FI117123B (sv) | 1994-11-08 | 1995-11-06 | Farmaceutisk komposition för oral administration av flavonoider |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0711560B1 (sv) |
JP (1) | JP3022952B2 (sv) |
KR (1) | KR960016901A (sv) |
CN (1) | CN1131538A (sv) |
AT (1) | ATE202480T1 (sv) |
AU (1) | AU706027B2 (sv) |
CA (1) | CA2162299C (sv) |
CY (1) | CY2265B1 (sv) |
DE (1) | DE69521477T2 (sv) |
DK (1) | DK0711560T3 (sv) |
ES (1) | ES2160145T3 (sv) |
FI (1) | FI117123B (sv) |
FR (1) | FR2726469B1 (sv) |
GR (1) | GR3036244T3 (sv) |
NO (1) | NO311402B1 (sv) |
NZ (1) | NZ280418A (sv) |
PT (1) | PT711560E (sv) |
ZA (1) | ZA959473B (sv) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE1011151A3 (fr) * | 1997-05-13 | 1999-05-04 | Jose Remacle | Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie. |
US6350470B1 (en) * | 1998-04-29 | 2002-02-26 | Cima Labs Inc. | Effervescent drug delivery system for oral administration |
JP4273277B2 (ja) * | 1999-06-30 | 2009-06-03 | 大塚製薬株式会社 | オリゴ糖補給組成物 |
JP2001158796A (ja) * | 1999-11-30 | 2001-06-12 | Toyo Seito Kk | α−グルコシルジオスミンの製造方法及びフラボノイド組成物 |
FR2845597B1 (fr) * | 2002-10-11 | 2005-03-11 | Innothera Lab Sa | Formulation orale seche contenant de la diosmine sous forme pharmaceutique de comprime a croquer |
AU2003263162B2 (en) | 2002-10-24 | 2009-05-07 | Immupharm A/S | Pharmaceutical compositions comprising flavonoids and menthol |
AT501682A1 (de) | 2005-01-14 | 2006-10-15 | Hermine Dr Engl | Verfahren zur herstellung einer wirkstoffmischung |
ITMI20050517A1 (it) | 2005-03-30 | 2006-09-30 | Therapicon Srl | Composizione farmaceutica di una tipica frazione microcristallina di flavonoidi |
ITMI20051942A1 (it) * | 2005-10-14 | 2007-04-15 | S I I T S R L Servizio Interna | Composizioni galattogeniche a base di silimarina |
WO2007062415A1 (en) * | 2005-11-26 | 2007-05-31 | Grinrx | Corporeal delivery of carotenoids |
MX2007011002A (es) * | 2007-09-07 | 2009-03-09 | World Trade Imp Export Wtie Ag | Composicion farmaceutica que comprende la combinacion de diversos agentes venotonicos y vasoprotectores para el tratamiento de la insuficiencia venosa cronica. |
WO2011019654A1 (en) * | 2009-08-10 | 2011-02-17 | Stokely-Van Camp, Inc. | Method for suspending a flavonoid in a beverage |
MD3987C2 (ro) * | 2009-09-03 | 2010-07-31 | Георге АНГЕЛИЧ | Utilizare a Diosminei pentru tratamentul cirozei hepatice avansate asociate cu insuficienţă cardiacă |
MD3986C2 (ro) * | 2009-09-23 | 2010-07-31 | Георге АНГЕЛИЧ | Utilizare a Diosminei pentru tratamentul gastropatiilor portale în ciroza hepatică |
MD4232C1 (ro) * | 2012-11-08 | 2014-01-31 | Георге АНГЕЛИЧ | Remediu medicamentos pe bază de troxerutin şi carbazocrom pentru tratamentul cirozei hepatice avansate asociate cu insuficienţă cardiacă |
MD4231C1 (ro) * | 2012-11-08 | 2014-01-31 | Георге АНГЕЛИЧ | Remediu medicamentos pe bază de troxerutin şi carbazocrom pentru tratamentul gastropatiilor portale în ciroza hepatică |
FR2999934B1 (fr) * | 2012-12-21 | 2015-02-20 | Servier Lab | Composition pharmaceutique sous la forme d'une suspension orale comprenant une fraction flavonoique et de la gomme xanthane |
CA3018828C (en) | 2014-09-17 | 2021-05-11 | Steerlife India Private Limited | Effervescent composition and method of making it |
WO2017098481A1 (en) | 2015-12-12 | 2017-06-15 | Steerlife India Private Limited | Effervescent compositions of metformin and processes for preparation thereof |
FR3083980B1 (fr) * | 2018-07-20 | 2021-04-16 | Servier Lab | Composition pharmaceutique sous la forme d'un comprime a croquer de diosmine ou d'une fraction flavonoique |
US10639294B2 (en) | 2018-10-02 | 2020-05-05 | Janssen Pharmaceutica Nv | Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide metabolite |
US11304968B2 (en) | 2018-11-16 | 2022-04-19 | Janssen Pharmaceutica Nv | Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide |
WO2021123341A1 (en) | 2019-12-20 | 2021-06-24 | Krka, D.D., Novo Mesto | Composition comprising diosmin |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR6967M (sv) * | 1968-01-22 | 1969-05-19 | ||
JPS52156913A (en) * | 1976-06-21 | 1977-12-27 | Toko Yakuhin Kogyo Kk | Production of injectionable medicine |
RO81345B1 (ro) * | 1980-07-28 | 1983-02-28 | Nicolae Oita | Medicament destinat insuficientei circulatorii periferice |
EP0172893A4 (en) * | 1984-03-01 | 1987-05-13 | John Royle Casley-Smith | TREATMENT OF OEDEMAS WITH A HIGH PROTEIN CONTENT IN ANIMALS. |
FR2577437A1 (fr) * | 1985-02-21 | 1986-08-22 | Corbiere Jerome | Nouveau procede de solubilisation des composes chimiques et les preparations aqueuses ainsi obtenues |
IT1201149B (it) * | 1987-01-14 | 1989-01-27 | Indena Spa | Complessi di bioflavonoidi con fosfolipidi,loro preparazione,uso e composizioni farmaceutici e cosmetiche |
FR2634376B1 (fr) * | 1988-07-21 | 1992-04-17 | Farmalyoc | Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation |
FR2661610B1 (fr) * | 1990-05-02 | 1994-09-30 | Rhone Poulenc Sante | Nouvelle forme lyophilisee de la diosmine et sa preparation. |
FR2661830B1 (fr) * | 1990-05-11 | 1992-09-04 | Corbiere Jerome | Nouvelle compositions pharmaceutiques a base de flavonoside. |
FR2668705A1 (fr) * | 1990-11-06 | 1992-05-07 | Bouchara Sa | Nouvelles preparations dermiques a action phlebotonique et leur procede de preparation. |
-
1994
- 1994-11-08 FR FR9413336A patent/FR2726469B1/fr not_active Expired - Fee Related
-
1995
- 1995-11-06 AU AU36695/95A patent/AU706027B2/en not_active Ceased
- 1995-11-06 FI FI955310A patent/FI117123B/sv not_active IP Right Cessation
- 1995-11-07 NZ NZ280418A patent/NZ280418A/en not_active IP Right Cessation
- 1995-11-07 CA CA002162299A patent/CA2162299C/fr not_active Expired - Fee Related
- 1995-11-07 NO NO19954455A patent/NO311402B1/no not_active IP Right Cessation
- 1995-11-07 CN CN95118756A patent/CN1131538A/zh active Pending
- 1995-11-07 PT PT95402476T patent/PT711560E/pt unknown
- 1995-11-07 ES ES95402476T patent/ES2160145T3/es not_active Expired - Lifetime
- 1995-11-07 DK DK95402476T patent/DK0711560T3/da active
- 1995-11-07 DE DE69521477T patent/DE69521477T2/de not_active Expired - Lifetime
- 1995-11-07 EP EP95402476A patent/EP0711560B1/fr not_active Expired - Lifetime
- 1995-11-07 JP JP7288467A patent/JP3022952B2/ja not_active Expired - Fee Related
- 1995-11-07 AT AT95402476T patent/ATE202480T1/de active
- 1995-11-08 KR KR1019950040899A patent/KR960016901A/ko not_active Application Discontinuation
- 1995-11-08 ZA ZA959473A patent/ZA959473B/xx unknown
-
2001
- 2001-07-19 GR GR20010401093T patent/GR3036244T3/el unknown
-
2002
- 2002-04-12 CY CY0200016A patent/CY2265B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE69521477T2 (de) | 2002-04-18 |
ATE202480T1 (de) | 2001-07-15 |
NO311402B1 (no) | 2001-11-26 |
FI955310A0 (sv) | 1995-11-06 |
JPH08208469A (ja) | 1996-08-13 |
NO954455L (no) | 1996-05-09 |
JP3022952B2 (ja) | 2000-03-21 |
NO954455D0 (no) | 1995-11-07 |
NZ280418A (en) | 1997-03-24 |
AU706027B2 (en) | 1999-06-10 |
EP0711560B1 (fr) | 2001-06-27 |
CA2162299C (fr) | 2008-09-09 |
KR960016901A (ko) | 1996-06-17 |
ES2160145T3 (es) | 2001-11-01 |
AU3669595A (en) | 1996-05-16 |
DK0711560T3 (da) | 2001-09-03 |
FR2726469A1 (fr) | 1996-05-10 |
FR2726469B1 (fr) | 1996-12-13 |
CA2162299A1 (fr) | 1996-05-09 |
FI955310A (sv) | 1996-05-09 |
CN1131538A (zh) | 1996-09-25 |
EP0711560A1 (fr) | 1996-05-15 |
DE69521477D1 (de) | 2001-08-02 |
GR3036244T3 (en) | 2001-10-31 |
PT711560E (pt) | 2001-10-30 |
CY2265B1 (en) | 2003-07-04 |
ZA959473B (en) | 1996-05-15 |
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Legal Events
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FG | Patent granted |
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