FI116999B - Menetelmä farmaseuttisen emulsion valmistamiseksi - Google Patents

Menetelmä farmaseuttisen emulsion valmistamiseksi Download PDF

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Publication number
FI116999B
FI116999B FI961999A FI961999A FI116999B FI 116999 B FI116999 B FI 116999B FI 961999 A FI961999 A FI 961999A FI 961999 A FI961999 A FI 961999A FI 116999 B FI116999 B FI 116999B
Authority
FI
Finland
Prior art keywords
dichlorophenyl
dicarboxylate
dimethyl
eller
emulsion
Prior art date
Application number
FI961999A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI961999A (fi
FI961999A0 (fi
Inventor
Kjell Hjalmar Andersson
Eva Kristina Byroed
Anna-Carin Hansson
Margareta Nordlander
Rolf Christer Westerlund
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of FI961999A publication Critical patent/FI961999A/fi
Publication of FI961999A0 publication Critical patent/FI961999A0/fi
Application granted granted Critical
Publication of FI116999B publication Critical patent/FI116999B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI961999A 1993-11-12 1996-05-10 Menetelmä farmaseuttisen emulsion valmistamiseksi FI116999B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9303744A SE9303744D0 (sv) 1993-11-12 1993-11-12 Pharmaceutical emulsion
SE9303744 1993-11-12
SE9401032 1994-11-03
PCT/SE1994/001032 WO1995013066A1 (en) 1993-11-12 1994-11-03 Pharmaceutical emulsion

Publications (3)

Publication Number Publication Date
FI961999A FI961999A (fi) 1996-05-10
FI961999A0 FI961999A0 (fi) 1996-05-10
FI116999B true FI116999B (fi) 2006-05-15

Family

ID=20391731

Family Applications (1)

Application Number Title Priority Date Filing Date
FI961999A FI116999B (fi) 1993-11-12 1996-05-10 Menetelmä farmaseuttisen emulsion valmistamiseksi

Country Status (31)

Country Link
US (1) US5739152A (ru)
EP (1) EP0727997B1 (ru)
JP (1) JP3759951B2 (ru)
KR (1) KR100345627B1 (ru)
CN (1) CN1072934C (ru)
AT (1) ATE213158T1 (ru)
AU (1) AU678650B2 (ru)
CA (1) CA2176360C (ru)
CZ (1) CZ290772B6 (ru)
DE (1) DE69429871T2 (ru)
DK (1) DK0727997T3 (ru)
EE (1) EE03223B1 (ru)
EG (1) EG20764A (ru)
ES (1) ES2172572T3 (ru)
FI (1) FI116999B (ru)
HK (1) HK1013261A1 (ru)
HU (1) HU223142B1 (ru)
IL (1) IL111345A (ru)
IS (1) IS2036B (ru)
MY (1) MY121201A (ru)
NO (1) NO314877B1 (ru)
NZ (1) NZ276197A (ru)
PL (1) PL181462B1 (ru)
PT (1) PT727997E (ru)
RU (1) RU2144358C1 (ru)
SA (1) SA94150314B1 (ru)
SE (1) SE9303744D0 (ru)
SK (1) SK283271B6 (ru)
UA (1) UA40633C2 (ru)
WO (1) WO1995013066A1 (ru)
ZA (1) ZA948180B (ru)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
DK1079808T3 (da) * 1998-05-29 2004-06-07 Skyepharma Canada Inc Præparater med termisk beskyttede mikropartikler og fremgangsmåde til slutdampsterilisering deraf
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
JP2005500293A (ja) 2001-06-15 2005-01-06 コーナーストーン ファーマシューティカルズ 標的とする組織及び細胞の治療に有用なナノ粒子を含む薬剤組成物及び診断のための組成物
ES2528669T3 (es) * 2003-04-08 2015-02-11 Progenics Pharmaceuticals, Inc. Formulaciones farmacéuticas que contienen metilnaltrexona
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
MX2009010550A (es) * 2007-03-29 2009-12-14 Progenics Pharm Inc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
PE20090700A1 (es) * 2007-03-29 2009-07-13 Progenics Pharm Inc Compuestos heterociclicos como antagonistas del receptor opioide periferico
PT2139890E (pt) * 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
WO2009099411A1 (en) 2008-02-06 2009-08-13 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
AU2009277100B2 (en) * 2008-08-01 2015-05-28 Chiesi Farmaceutici S.P.A. Pharmaceutical compositions and methods for stabilizing the same
AU2009276560B2 (en) * 2008-08-01 2015-04-16 Chiesi Farmaceutici S.P.A. Pharmaceutical compositions and methods for producing low impurity concentrations of the same
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
US9034389B2 (en) * 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
CN101780036B (zh) * 2010-03-30 2011-11-16 武汉武药科技有限公司 丁酸氯维地平脂微球注射液及其制备方法
ES2539861T5 (es) 2010-10-12 2018-11-16 Chiesi Farmaceutici S.P.A. Formulaciones en emulsión de clevidipina que contienen agentes antimicrobianos
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
CN102531998A (zh) * 2010-12-09 2012-07-04 天津药物研究院 α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) * 2010-12-30 2012-07-04 天津药物研究院 一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) * 2011-02-17 2012-08-23 Cima Labs Inc. Dosage forms for weakly ionizable compounds
US20150094344A1 (en) * 2011-04-01 2015-04-02 The Medicines Company Short-acting dihydropyridines (clevidipine) for use in reducing stroke damage
JP6339940B2 (ja) 2011-12-20 2018-06-06 ビョーメ バイオサイエンシズ ピーブイティー．リミテッド 真菌感染症の治療用の局所用オイル組成物
NZ708511A (en) 2012-10-26 2018-11-30 Chiesi Farm Spa Methods for controlling blood pressure and reducing dyspnea in heart failure
CN103110580B (zh) * 2013-02-20 2014-09-17 北京德立福瑞医药科技有限公司 丁酸氯维地平注射剂
EA201591954A1 (ru) * 2013-04-12 2016-04-29 Вайом Байосайнсиз Пвт. Лтд. Композиция и состав противомикробных средств, способы их получения и способы лечения микробных инфекций
PL3145508T3 (pl) 2014-05-19 2023-10-23 Chiesi Farmaceutici S.P.A. Nanocząstki klewidypiny i ich kompozycje farmaceutyczne

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) * 1992-05-29 1993-12-02 Dietl Hans Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
IS2036B (is) 2005-08-15
EE03223B1 (et) 1999-10-15
US5739152A (en) 1998-04-14
NO961898L (no) 1996-06-25
EG20764A (en) 2000-01-31
DE69429871T2 (de) 2002-08-22
HK1013261A1 (en) 1999-08-20
IL111345A0 (en) 1994-12-29
FI961999A (fi) 1996-05-10
CZ290772B6 (cs) 2002-10-16
HUT74474A (en) 1996-12-30
NZ276197A (en) 1997-04-24
SE9303744D0 (sv) 1993-11-12
MY121201A (en) 2006-01-28
NO961898D0 (no) 1996-05-10
UA40633C2 (ru) 2001-08-15
AU1037195A (en) 1995-05-29
CA2176360C (en) 2005-08-23
SK59796A3 (en) 1996-12-04
CN1072934C (zh) 2001-10-17
ES2172572T3 (es) 2002-10-01
IL111345A (en) 2000-08-31
HU9601268D0 (en) 1996-07-29
EP0727997B1 (en) 2002-02-13
CZ133896A3 (en) 1996-09-11
AU678650B2 (en) 1997-06-05
IS4224A (is) 1995-05-13
EP0727997A1 (en) 1996-08-28
KR100345627B1 (ko) 2003-03-15
PL181462B1 (pl) 2001-07-31
HU223142B1 (hu) 2004-03-29
PT727997E (pt) 2002-07-31
ZA948180B (en) 1995-05-12
DK0727997T3 (da) 2002-04-22
SA94150314B1 (ar) 2005-06-14
CA2176360A1 (en) 1995-05-18
CN1136774A (zh) 1996-11-27
JP3759951B2 (ja) 2006-03-29
PL314263A1 (en) 1996-09-02
WO1995013066A1 (en) 1995-05-18
RU2144358C1 (ru) 2000-01-20
DE69429871D1 (de) 2002-03-21
ATE213158T1 (de) 2002-02-15
JPH09505045A (ja) 1997-05-20
SK283271B6 (sk) 2003-04-01
FI961999A0 (fi) 1996-05-10
NO314877B1 (no) 2003-06-10

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