ES2172572T3 - Emulsion farmaceutica. - Google Patents

Emulsion farmaceutica.

Info

Publication number
ES2172572T3
ES2172572T3 ES95900965T ES95900965T ES2172572T3 ES 2172572 T3 ES2172572 T3 ES 2172572T3 ES 95900965 T ES95900965 T ES 95900965T ES 95900965 T ES95900965 T ES 95900965T ES 2172572 T3 ES2172572 T3 ES 2172572T3
Authority
ES
Spain
Prior art keywords
pharmaceutical emulsion
emulsion
pharmaceutical
dihydropiridine
emulsor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95900965T
Other languages
English (en)
Inventor
Kjell Hjalmar Andersson
Eva Kristina Byrod
Anna-Carin Hansson
Margareta Nordlander
Rolf Christer Westerlund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2172572T3 publication Critical patent/ES2172572T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA EMULSION FARMACEUTICA QUE CONTIENE (A) UN COMPUESTO DE DIHIDROPIRIDINA DE ACTUACION RAPIDA; (B) UNA FASE LIPIDA; (C) UN EMULSOR; Y (D) AGUA O UN TAMPON, AL USO DE Y AL PROCEDIMIENTO PARA LA PREPARACION DE LA EMULSION.
ES95900965T 1993-11-12 1994-11-03 Emulsion farmaceutica. Expired - Lifetime ES2172572T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9303744A SE9303744D0 (sv) 1993-11-12 1993-11-12 Pharmaceutical emulsion

Publications (1)

Publication Number Publication Date
ES2172572T3 true ES2172572T3 (es) 2002-10-01

Family

ID=20391731

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95900965T Expired - Lifetime ES2172572T3 (es) 1993-11-12 1994-11-03 Emulsion farmaceutica.

Country Status (30)

Country Link
US (1) US5739152A (es)
EP (1) EP0727997B1 (es)
JP (1) JP3759951B2 (es)
KR (1) KR100345627B1 (es)
CN (1) CN1072934C (es)
AT (1) ATE213158T1 (es)
AU (1) AU678650B2 (es)
CA (1) CA2176360C (es)
CZ (1) CZ290772B6 (es)
DE (1) DE69429871T2 (es)
DK (1) DK0727997T3 (es)
EE (1) EE03223B1 (es)
EG (1) EG20764A (es)
ES (1) ES2172572T3 (es)
FI (1) FI116999B (es)
HU (1) HU223142B1 (es)
IL (1) IL111345A (es)
IS (1) IS2036B (es)
MY (1) MY121201A (es)
NO (1) NO314877B1 (es)
NZ (1) NZ276197A (es)
PL (1) PL181462B1 (es)
PT (1) PT727997E (es)
RU (1) RU2144358C1 (es)
SA (1) SA94150314B1 (es)
SE (1) SE9303744D0 (es)
SK (1) SK283271B6 (es)
UA (1) UA40633C2 (es)
WO (1) WO1995013066A1 (es)
ZA (1) ZA948180B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
ES2216517T3 (es) * 1998-05-29 2004-10-16 Skyepharma Canada Inc. Composiciones de microcapsulas termoprotegidas y procedimiento para su esterilizacion terminal con vapor.
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
WO2002102311A2 (en) 2001-06-15 2002-12-27 Cornerstone Pharmaceuticals Nanoparticles for treating targeted tissues and cells
ES2528669T3 (es) * 2003-04-08 2015-02-11 Progenics Pharmaceuticals, Inc. Formulaciones farmacéuticas que contienen metilnaltrexona
AR057325A1 (es) * 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) * 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
PE20090700A1 (es) * 2007-03-29 2009-07-13 Progenics Pharm Inc Compuestos heterociclicos como antagonistas del receptor opioide periferico
BRPI0809579B8 (pt) 2007-03-29 2021-05-25 Progenics Pharm Inc formas cristalinas e seus usos
PL2139890T3 (pl) * 2007-03-29 2014-11-28 Wyeth Llc Antagoniści obwodowych receptorów opioidowych i ich zastosowania
WO2009099411A1 (en) 2008-02-06 2009-08-13 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
EP2320740B1 (en) * 2008-08-01 2014-03-26 The Medicines Company Pharmaceutical compositions of clevidipine and methods for producing low impurity concentrations of the same
MX2011001241A (es) * 2008-08-01 2011-08-03 Medicines Co Composiciones farmaceuticas y metodos para estabilizar las mismas.
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
US9034389B2 (en) * 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
CN101780036B (zh) * 2010-03-30 2011-11-16 武汉武药科技有限公司 丁酸氯维地平脂微球注射液及其制备方法
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
BR112013008601B1 (pt) 2010-10-12 2020-03-31 Chiesi Farmaceutici S.P.A. Formulações de emulsão de clevidipina contendo agentes antimicrobianos
CN102531998A (zh) * 2010-12-09 2012-07-04 天津药物研究院 α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) * 2010-12-30 2012-07-04 天津药物研究院 一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) * 2011-02-17 2012-08-23 Cima Labs Inc. Dosage forms for weakly ionizable compounds
BR112013025368A8 (pt) * 2011-04-01 2018-06-12 The Medicines Co Medicamento, método para preparar um medicamento útil para reduzir danos por derrame em um sujeito com derrame, método para preparar um medicamento útil para reduzir a pressão sanguínea e reduzir danos por derrame em um sujeito com derrame
EP2793833B1 (en) 2011-12-20 2020-06-24 Vyome Therapeutics Limited Topical oil composition for the treatment of fungal infections
CN110840890A (zh) 2012-10-26 2020-02-28 凯西制药公司 用于在心力衰竭中控制血压和减轻呼吸困难的方法
CN103110580B (zh) * 2013-02-20 2014-09-17 北京德立福瑞医药科技有限公司 丁酸氯维地平注射剂
CN105263525A (zh) * 2013-04-12 2016-01-20 维奥姆生物科学有限公司 抗微生物剂的组合物和制剂、它们的方法以及用于治疗微生物感染的方法
MX385243B (es) 2014-05-19 2025-03-14 The Medicines Co Nanoparticulas de clevidipina y composiciones farmaceuticas que las contienen.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) * 1992-05-29 1993-12-02 Dietl Hans Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
JP3759951B2 (ja) 2006-03-29
HK1013261A1 (en) 1999-08-20
HU9601268D0 (en) 1996-07-29
US5739152A (en) 1998-04-14
NZ276197A (en) 1997-04-24
CN1072934C (zh) 2001-10-17
AU1037195A (en) 1995-05-29
MY121201A (en) 2006-01-28
CZ133896A3 (en) 1996-09-11
IL111345A0 (en) 1994-12-29
JPH09505045A (ja) 1997-05-20
EE03223B1 (et) 1999-10-15
ZA948180B (en) 1995-05-12
CA2176360C (en) 2005-08-23
CA2176360A1 (en) 1995-05-18
SK59796A3 (en) 1996-12-04
UA40633C2 (uk) 2001-08-15
PL181462B1 (pl) 2001-07-31
NO961898D0 (no) 1996-05-10
ATE213158T1 (de) 2002-02-15
FI961999A0 (fi) 1996-05-10
IL111345A (en) 2000-08-31
DE69429871D1 (de) 2002-03-21
NO314877B1 (no) 2003-06-10
EG20764A (en) 2000-01-31
EP0727997A1 (en) 1996-08-28
SA94150314B1 (ar) 2005-06-14
CN1136774A (zh) 1996-11-27
FI116999B (fi) 2006-05-15
WO1995013066A1 (en) 1995-05-18
DK0727997T3 (da) 2002-04-22
IS4224A (is) 1995-05-13
KR100345627B1 (ko) 2003-03-15
PL314263A1 (en) 1996-09-02
PT727997E (pt) 2002-07-31
RU2144358C1 (ru) 2000-01-20
EP0727997B1 (en) 2002-02-13
IS2036B (is) 2005-08-15
AU678650B2 (en) 1997-06-05
SE9303744D0 (sv) 1993-11-12
FI961999L (fi) 1996-05-10
CZ290772B6 (cs) 2002-10-16
HUT74474A (en) 1996-12-30
HU223142B1 (hu) 2004-03-29
SK283271B6 (sk) 2003-04-01
DE69429871T2 (de) 2002-08-22
NO961898L (no) 1996-06-25

Similar Documents

Publication Publication Date Title
ES2172572T3 (es) Emulsion farmaceutica.
MX9204268A (es) Una composicion para la liberacion prolongada y controlada de substancias medicamentosas y un proceso para preparar la misma.
AR027162A1 (es) Compuestos de 2-fenil-3-fenoxilo-feniltio-benzotiofeno, sales farmaceuticamente aceptables de los mismos y composiciones farmaceuticas que los contienen
MX9205432A (es) Compuestos inhibidores de la biosintesis de leucotrienos y composicion farmaceutica que los contiene.
MX9201082A (es) Procedimiento para la preparacion de una composicion farmaceutica que comprende gases propelentes libres de cloro.
ES556056A0 (es) Un procedimiento para la preparacion de una emulsion de lipidos.
MX9102501A (es) Derivados de metano sulfonamida, composiciones farderivados de metanosulfonamida, composiciones farmaceuticas que los contienen y procedimiento para smaceuticas que los contienen y procedimiento para u preparacion. su preparacion.
ES557835A0 (es) Un procedimiento para preparar una formulacion farmaceutica que contiene 3'-azido-3'-desoxitimidina o uno de sus derivados farmaceuticamente aceptables.
MX9202619A (es) Derivados de oxa tiolano cristalino, metodo para su preparacion y formulacion farmaceutica que los contiene.
ES2100151T3 (es) Nuevos derivados de benzopirano, procedimientos para su preparacion y su uso y composiciones que contienen los compuestos.
ES2177584T3 (es) Composicion de prostaglandinas transdermica.
ES547738A0 (es) Un procedimiento para la preparacion de una composicion terapeutica que contiene un fosfato de dialquilo.
DK155389D0 (da) Praeparater indeholdende thymol, herunder mundhygiejnepraeparater, til maskering af smagen af thymol
MX9204140A (es) Nuevos derivados de analogos de taxol, procedimiento para su preparacion y composicion farmaceutica que los contienen.
NO964639L (no) Substituerte sulfonimidamider, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen
ES2086771T3 (es) Composicion dermatologica y/o cosmetologica que contiene retinoides.
AR012125A1 (es) UNA SAL DE UN COMPUESTO DERIVADO DEL ÁCIDO NAFTIRIDINA CARBOXíLICO , SU USO PARA LA FABRICACIoN DE UN MEDICAMENTO , PROCEDIMIENTO PARA PREPARARLA Y UNA COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE
MX9207222A (es) Procedimiento para la preparacion de compuestos farmaceuticos que reducen selectivamente el nivel de lipidos de la sangre.
ES2183180T3 (es) Nuevos derivados de guanidina, procedimientos para su preparacion y su uso como medicamento.
SE8904298D0 (sv) New compounds
BR9609327A (pt) Novos derivados de oxazolidinona processos para sua preparação e agentes farmacêuticos que contêm estes compostos
AR002157A1 (es) Uso de una dosis inmunizante eficaz de esporozoitos o merozoitos de eimeria vivos, o una mezcla de los mismos
CY1105465T1 (el) Μορφη δοσολογιας πepιλαμβανουσα υγρο σκευασμα
MX9204237A (es) Nuevos derivados de ciclohexano y tetrahidropiran, procedimiento para su preparacion y composicion antifungal que los contiene.
ES2105605T3 (es) Antagonistas de taquiquinina, su preparacion y utilizacion en formulaciones farmaceuticas.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 727997

Country of ref document: ES